This is a Validated Antibody Database (VAD) review about rat Top2b, based on 4 published articles (read how Labome selects the articles), using Top2b antibody in all methods. It is aimed to help Labome visitors find the most suited Top2b antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Top2b synonym: DNA topoisomerase 2-beta; topoisomerase (DNA) II beta; topoisomerase II beta

Santa Cruz Biotechnology
mouse monoclonal (H-8)
  • immunohistochemistry; mouse; 1:300; loading ...; fig 4b
Santa Cruz Biotechnology Top2b antibody (Santa Cruz, sc-25330) was used in immunohistochemistry on mouse samples at 1:300 (fig 4b). J Neurosci Res (2017) ncbi
mouse monoclonal (H-8)
  • western blot; human; 1:1000
Santa Cruz Biotechnology Top2b antibody (Santa Cruz Biotechnology, sc-25330) was used in western blot on human samples at 1:1000. J Neuroimmunol (2014) ncbi
mouse monoclonal (H-8)
  • immunohistochemistry; human; fig 3
  • western blot; human; fig 3
  • immunohistochemistry; mouse; fig 3
  • western blot; mouse; fig 3
In order to study the roles of Top2-alpha and -beta in mitochondria and the effect on mitochondrial DNA supercoiling of Top1mt deletion, Santa Cruz Biotechnology Top2b antibody (Santa Cruz, sc-25330) was used in immunohistochemistry on human samples (fig 3), in western blot on human samples (fig 3), in immunohistochemistry on mouse samples (fig 3) and in western blot on mouse samples (fig 3). Nucleic Acids Res (2014) ncbi
mouse monoclonal (H-8)
  • western blot; mouse
Santa Cruz Biotechnology Top2b antibody (Santa Cruz, sc-25330) was used in western blot on mouse samples . Drug Discov Ther (2014) ncbi
Articles Reviewed
  1. Li Y, Hao H, Swerdel M, Cho H, Lee K, Hart R, et al. Top2b is involved in the formation of outer segment and synapse during late-stage photoreceptor differentiation by controlling key genes of photoreceptor transcriptional regulatory network. J Neurosci Res. 2017;95:1951-1964 pubmed publisher
  2. Kong L, Wei J, Haider A, Liebelt B, Ling X, Conrad C, et al. Therapeutic targets in subependymoma. J Neuroimmunol. 2014;277:168-75 pubmed publisher
  3. Zhang H, Zhang Y, Yasukawa T, Dalla Rosa I, Khiati S, Pommier Y. Increased negative supercoiling of mtDNA in TOP1mt knockout mice and presence of topoisomerases II? and II? in vertebrate mitochondria. Nucleic Acids Res. 2014;42:7259-67 pubmed publisher
  4. Wang R, Wang Y, Gao Z, Qu X. The comparative study of acetyl-11-keto-beta-boswellic acid (AKBA) and aspirin in the prevention of intestinal adenomatous polyposis in APC(Min/+) mice. Drug Discov Ther. 2014;8:25-32 pubmed