This is a Validated Antibody Database (VAD) review about rat Tnfrsf1a, based on 36 published articles (read how Labome selects the articles), using Tnfrsf1a antibody in all methods. It is aimed to help Labome visitors find the most suited Tnfrsf1a antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Tnfrsf1a synonym: TNFR-1; Tnfr1

Santa Cruz Biotechnology
mouse monoclonal (H-5)
  • western blot; human; 1:1000; loading ...; fig 6b
Santa Cruz Biotechnology Tnfrsf1a antibody (Santa Cruz, sc-8436) was used in western blot on human samples at 1:1000 (fig 6b). EMBO Mol Med (2022) ncbi
mouse monoclonal (H-5)
  • western blot; human; loading ...; fig 3b
Santa Cruz Biotechnology Tnfrsf1a antibody (Santa Cruz Biotechnology, sc-8436) was used in western blot on human samples (fig 3b). Sci Rep (2021) ncbi
mouse monoclonal (H-5)
  • western blot; human; 1:1000; loading ...; fig 5a, 5e
Santa Cruz Biotechnology Tnfrsf1a antibody (Santa Cruz, sc-8436) was used in western blot on human samples at 1:1000 (fig 5a, 5e). Front Cell Dev Biol (2021) ncbi
mouse monoclonal (H-5)
  • western blot; mouse; loading ...; fig 2e
Santa Cruz Biotechnology Tnfrsf1a antibody (Santa Cruz, SC-8436) was used in western blot on mouse samples (fig 2e). Nat Commun (2020) ncbi
mouse monoclonal (H-5)
  • western blot; human; loading ...; fig 2d
Santa Cruz Biotechnology Tnfrsf1a antibody (Santa Cruz Biotechnology, sc-8436) was used in western blot on human samples (fig 2d). Sci Adv (2019) ncbi
mouse monoclonal (H-5)
  • western blot; human; fig 3f
Santa Cruz Biotechnology Tnfrsf1a antibody (Santa Cruz, sc-8436) was used in western blot on human samples (fig 3f). Cell Death Differ (2019) ncbi
mouse monoclonal (H-5)
  • western blot; mouse; 1:1000; loading ...; fig 8a
Santa Cruz Biotechnology Tnfrsf1a antibody (Santa Cruz Biotechnology Inc, sc-8436) was used in western blot on mouse samples at 1:1000 (fig 8a). J Neuroinflammation (2018) ncbi
mouse monoclonal (H-5)
  • western blot; rat; loading ...; fig 2c
Santa Cruz Biotechnology Tnfrsf1a antibody (Santa Cruz Biotechnology, sc-8436) was used in western blot on rat samples (fig 2c). J Neurosci (2018) ncbi
mouse monoclonal (H-5)
  • western blot; human; loading ...; fig 2a
Santa Cruz Biotechnology Tnfrsf1a antibody (Santa Cruz Biotechnology, sc-8436) was used in western blot on human samples (fig 2a). Sci Rep (2017) ncbi
hamsters monoclonal (55R-170)
  • flow cytometry; mouse; loading ...; fig 1a
Santa Cruz Biotechnology Tnfrsf1a antibody (Santa Cruz Biotechnology, sc-12746) was used in flow cytometry on mouse samples (fig 1a). Cell Death Dis (2016) ncbi
mouse monoclonal (H-5)
  • western blot; human; fig 1
Santa Cruz Biotechnology Tnfrsf1a antibody (Santa Cruz, 8436) was used in western blot on human samples (fig 1). Cell Rep (2016) ncbi
mouse monoclonal (H-5)
  • western blot; human; fig 1
Santa Cruz Biotechnology Tnfrsf1a antibody (Santa Cruz, sc-8436) was used in western blot on human samples (fig 1). Int J Mol Med (2016) ncbi
mouse monoclonal (G-2)
  • immunohistochemistry; rat; 1:200; fig 6
Santa Cruz Biotechnology Tnfrsf1a antibody (Santa Cruz, sc-374185) was used in immunohistochemistry on rat samples at 1:200 (fig 6). Mol Med Rep (2016) ncbi
hamsters monoclonal (55R-170)
  • immunoprecipitation; mouse; fig 5
Santa Cruz Biotechnology Tnfrsf1a antibody (Santa Cruz, sc-12746) was used in immunoprecipitation on mouse samples (fig 5). Cell Rep (2016) ncbi
mouse monoclonal (H-5)
  • western blot; mouse; fig 5
Santa Cruz Biotechnology Tnfrsf1a antibody (Santa Cruz, sc-8436) was used in western blot on mouse samples (fig 5). Cell Rep (2016) ncbi
mouse monoclonal (H-5)
  • western blot; human; fig 3
Santa Cruz Biotechnology Tnfrsf1a antibody (Santa Cruz, sc-8436) was used in western blot on human samples (fig 3). Biochem Biophys Res Commun (2016) ncbi
mouse monoclonal (H-5)
  • immunoprecipitation; human; 1:100; fig 5
  • western blot; human; 1:200; fig 5
Santa Cruz Biotechnology Tnfrsf1a antibody (Santa Cruz, sc-8436) was used in immunoprecipitation on human samples at 1:100 (fig 5) and in western blot on human samples at 1:200 (fig 5). J Biol Chem (2016) ncbi
mouse monoclonal (H-5)
  • western blot; human; fig 6A
  • immunohistochemistry; mouse; fig 8A
Santa Cruz Biotechnology Tnfrsf1a antibody (Santa Cruz, sc-8436) was used in western blot on human samples (fig 6A) and in immunohistochemistry on mouse samples (fig 8A). PLoS ONE (2015) ncbi
mouse monoclonal (H-5)
  • immunohistochemistry; rat; 1:50; fig 4
Santa Cruz Biotechnology Tnfrsf1a antibody (Santa Cruz, sc8436) was used in immunohistochemistry on rat samples at 1:50 (fig 4). PLoS ONE (2015) ncbi
mouse monoclonal (H-5)
  • immunoprecipitation; human
Santa Cruz Biotechnology Tnfrsf1a antibody (Santa Cruz Biotechnology, sc-8436) was used in immunoprecipitation on human samples . Oncogene (2016) ncbi
mouse monoclonal (H-5)
  • western blot; human
In order to evaluate the effect of tumor necrosis factor on claudin-5 endothelial tight junction barriers, Santa Cruz Biotechnology Tnfrsf1a antibody (Santa Cruz Biotechnology, sc-8436) was used in western blot on human samples . PLoS ONE (2015) ncbi
mouse monoclonal (H-5)
  • western blot; rat
Santa Cruz Biotechnology Tnfrsf1a antibody (Santa Cruz, Sc-8436) was used in western blot on rat samples . Cell Biol Toxicol (2015) ncbi
mouse monoclonal (H-5)
  • western blot; human
Santa Cruz Biotechnology Tnfrsf1a antibody (Santa Cruz Biotechnology, SC-8436) was used in western blot on human samples . J Biol Chem (2015) ncbi
mouse monoclonal (H-5)
  • western blot; human; fig 1
Santa Cruz Biotechnology Tnfrsf1a antibody (Santa Cruz, H5) was used in western blot on human samples (fig 1). Cell Death Dis (2015) ncbi
mouse monoclonal (H-5)
  • western blot; rat; 1:100
Santa Cruz Biotechnology Tnfrsf1a antibody (Santa Cruz Biotechnology, SC-8436) was used in western blot on rat samples at 1:100. Mol Vis (2014) ncbi
mouse monoclonal (H-5)
  • western blot; human; loading ...; fig 3
Santa Cruz Biotechnology Tnfrsf1a antibody (Santa Cruz Biotechnology, sc-8436) was used in western blot on human samples (fig 3). Breast Cancer Res Treat (2014) ncbi
mouse monoclonal (H-5)
  • immunoprecipitation; mouse
Santa Cruz Biotechnology Tnfrsf1a antibody (Santa Cruz Biotechnology, SC-8436) was used in immunoprecipitation on mouse samples . Cell Signal (2014) ncbi
mouse monoclonal (H-5)
  • immunoprecipitation; human; loading ...; fig 4a
  • western blot; human; 1:1000; loading ...; fig 4a
Santa Cruz Biotechnology Tnfrsf1a antibody (Santa Cruz Biotechnology, sc-8436) was used in immunoprecipitation on human samples (fig 4a) and in western blot on human samples at 1:1000 (fig 4a). Carcinogenesis (2014) ncbi
mouse monoclonal (H-5)
  • western blot; human
Santa Cruz Biotechnology Tnfrsf1a antibody (Santa Cruz Biotechnology, sc-8436) was used in western blot on human samples . Carcinogenesis (2009) ncbi
Abcam
domestic rabbit polyclonal
  • immunohistochemistry - frozen section; mouse; 1:150; loading ...; fig 4c
Abcam Tnfrsf1a antibody (Abcam, ab223352) was used in immunohistochemistry - frozen section on mouse samples at 1:150 (fig 4c). Nat Immunol (2022) ncbi
domestic rabbit polyclonal
  • immunohistochemistry; human; loading ...; fig 1d
Abcam Tnfrsf1a antibody (Abcam, ab19139) was used in immunohistochemistry on human samples (fig 1d). Exp Ther Med (2021) ncbi
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig 2e
Abcam Tnfrsf1a antibody (Abcam, ab223352) was used in western blot on mouse samples (fig 2e). Cell Death Dis (2021) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig 1a
Abcam Tnfrsf1a antibody (Abcam, ab19139) was used in western blot on mouse samples at 1:1000 (fig 1a). Mol Metab (2020) ncbi
domestic rabbit polyclonal
  • flow cytometry; human; loading ...; fig s4a
Abcam Tnfrsf1a antibody (Abcam, ab19139) was used in flow cytometry on human samples (fig s4a). Mol Cancer Res (2019) ncbi
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig 2a
Abcam Tnfrsf1a antibody (Abcam, ab19139) was used in western blot on mouse samples (fig 2a). Nature (2018) ncbi
domestic rabbit polyclonal
  • western blot; bovine; loading ...; fig s1
Abcam Tnfrsf1a antibody (Abcam, ab19139) was used in western blot on bovine samples (fig s1). Reprod Fertil Dev (2017) ncbi
R&D Systems
rat monoclonal (47803)
  • western blot; mouse; 1:2000; loading ...; fig 5a
R&D Systems Tnfrsf1a antibody (R&D Systems Inc, MAB425) was used in western blot on mouse samples at 1:2000 (fig 5a). J Cell Sci (2019) ncbi
Articles Reviewed
  1. Fischer A, Wannemacher J, Christ S, Koopmans T, Kadri S, Zhao J, et al. Neutrophils direct preexisting matrix to initiate repair in damaged tissues. Nat Immunol. 2022;23:518-531 pubmed publisher
  2. Zinngrebe J, Moepps B, Monecke T, Gierschik P, Schlichtig F, Barth T, et al. Compound heterozygous variants in OTULIN are associated with fulminant atypical late-onset ORAS. EMBO Mol Med. 2022;14:e14901 pubmed publisher
  3. Lin C, Huang P, Chen C, Wu M, Chen J, Chen J, et al. Sitagliptin attenuates arterial calcification by downregulating oxidative stress-induced receptor for advanced glycation end products in LDLR knockout mice. Sci Rep. 2021;11:17851 pubmed publisher
  4. Pang K, Ghim M, Liu C, Tay H, Fhu C, Chia R, et al. Leucine-Rich α-2-Glycoprotein 1 Suppresses Endothelial Cell Activation Through ADAM10-Mediated Shedding of TNF-α Receptor. Front Cell Dev Biol. 2021;9:706143 pubmed publisher
  5. Li Q, Cheng F, Zhou K, Fang L, Wu J, Xia Q, et al. Increased sensitivity to TNF-α promotes keloid fibroblast hyperproliferation by activating the NF-κB, JNK and p38 MAPK pathways. Exp Ther Med. 2021;21:502 pubmed publisher
  6. Moujalled D, Gangatirkar P, Kauppi M, Corbin J, Lebois M, Murphy J, et al. The necroptotic cell death pathway operates in megakaryocytes, but not in platelet synthesis. Cell Death Dis. 2021;12:133 pubmed publisher
  7. Li X, Zhang M, Huang X, Liang W, Li G, Lu X, et al. Ubiquitination of RIPK1 regulates its activation mediated by TNFR1 and TLRs signaling in distinct manners. Nat Commun. 2020;11:6364 pubmed publisher
  8. Xu M, Ge C, Qin Y, Lou D, Li Q, Feng J, et al. Functional loss of inactive rhomboid-like protein 2 mitigates obesity by suppressing pro-inflammatory macrophage activation-triggered adipose inflammation. Mol Metab. 2020;34:112-123 pubmed publisher
  9. Izadi D, Layton T, Williams L, McCann F, Cabrita M, Espirito Santo A, et al. Identification of TNFR2 and IL-33 as therapeutic targets in localized fibrosis. Sci Adv. 2019;5:eaay0370 pubmed publisher
  10. Wang Z, Feng J, Yu J, Chen G. FKBP12 mediates necroptosis by initiating RIPK1-RIPK3-MLKL signal transduction in response to TNF receptor 1 ligation. J Cell Sci. 2019;132: pubmed publisher
  11. Vickman R, Yang J, Lanman N, Cresswell G, Zheng F, Zhang C, et al. Cholesterol Sulfotransferase SULT2B1b Modulates Sensitivity to Death Receptor Ligand TNFα in Castration-Resistant Prostate Cancer. Mol Cancer Res. 2019;17:1253-1263 pubmed publisher
  12. Fauster A, Rebsamen M, Willmann K, César Razquin A, Girardi E, Bigenzahn J, et al. Systematic genetic mapping of necroptosis identifies SLC39A7 as modulator of death receptor trafficking. Cell Death Differ. 2019;26:1138-1155 pubmed publisher
  13. Han L, Wang L, Tang S, Yuan L, Wu S, Du X, et al. ITGB4 deficiency in bronchial epithelial cells directs airway inflammation and bipolar disorder-related behavior. J Neuroinflammation. 2018;15:246 pubmed publisher
  14. Peltzer N, Darding M, Montinaro A, Dráber P, Draberova H, Kupka S, et al. LUBAC is essential for embryogenesis by preventing cell death and enabling haematopoiesis. Nature. 2018;557:112-117 pubmed publisher
  15. Mironets E, Osei Owusu P, Bracchi Ricard V, Fischer R, Owens E, Ricard J, et al. Soluble TNFα Signaling within the Spinal Cord Contributes to the Development of Autonomic Dysreflexia and Ensuing Vascular and Immune Dysfunction after Spinal Cord Injury. J Neurosci. 2018;38:4146-4162 pubmed publisher
  16. Zhao L, Zhang B. Doxorubicin induces cardiotoxicity through upregulation of death receptors mediated apoptosis in cardiomyocytes. Sci Rep. 2017;7:44735 pubmed publisher
  17. Siegmund D, Kums J, Ehrenschwender M, Wajant H. Activation of TNFR2 sensitizes macrophages for TNFR1-mediated necroptosis. Cell Death Dis. 2016;7:e2375 pubmed publisher
  18. Kupka S, De Miguel D, Dráber P, Martino L, Surinova S, Rittinger K, et al. SPATA2-Mediated Binding of CYLD to HOIP Enables CYLD Recruitment to Signaling Complexes. Cell Rep. 2016;16:2271-80 pubmed publisher
  19. Wu S, Kanda T, Nakamoto S, Jiang X, Nakamura M, Sasaki R, et al. Cooperative effects of hepatitis B virus and TNF may play important roles in the activation of metabolic pathways through the activation of NF-?B. Int J Mol Med. 2016;38:475-81 pubmed publisher
  20. Dong Y, Bao C, Yu J, Liu X. Receptor-interacting protein kinase 3-mediated programmed cell necrosis in rats subjected to focal cerebral ischemia-reperfusion injury. Mol Med Rep. 2016;14:728-36 pubmed publisher
  21. Horihata K, Yoshioka S, Sano M, Yamamoto Y, Kimura K, Skarzynski D, et al. Expressions of lipoprotein receptors and cholesterol efflux regulatory proteins during luteolysis in bovine corpus luteum. Reprod Fertil Dev. 2017;29:1280-1286 pubmed publisher
  22. Tortola L, Nitsch R, Bertrand M, Kogler M, Redouane Y, Kozieradzki I, et al. The Tumor Suppressor Hace1 Is a Critical Regulator of TNFR1-Mediated Cell Fate. Cell Rep. 2016;15:1481-1492 pubmed publisher
  23. Emmerich C, Bakshi S, Kelsall I, Ortiz Guerrero J, Shpiro N, Cohen P. Lys63/Met1-hybrid ubiquitin chains are commonly formed during the activation of innate immune signalling. Biochem Biophys Res Commun. 2016;474:452-461 pubmed publisher
  24. Chhibber Goel J, Coleman Vaughan C, Agrawal V, Sawhney N, Hickey E, Powell J, et al. γ-Secretase Activity Is Required for Regulated Intramembrane Proteolysis of Tumor Necrosis Factor (TNF) Receptor 1 and TNF-mediated Pro-apoptotic Signaling. J Biol Chem. 2016;291:5971-85 pubmed publisher
  25. Lin C, Huang P, Lai C, Chen J, Lin S, Chen J. Simvastatin Attenuates Oxidative Stress, NF-κB Activation, and Artery Calcification in LDLR-/- Mice Fed with High Fat Diet via Down-regulation of Tumor Necrosis Factor-α and TNF Receptor 1. PLoS ONE. 2015;10:e0143686 pubmed publisher
  26. Yang H, Zhang M, Wang X, Zhang H, Zhang J, Jing L, et al. TNF Accelerates Death of Mandibular Condyle Chondrocytes in Rats with Biomechanical Stimulation-Induced Temporomandibular Joint Disease. PLoS ONE. 2015;10:e0141774 pubmed publisher
  27. Lee C, Yang Y, Chen C, Liu J. Syk-mediated tyrosine phosphorylation of mule promotes TNF-induced JNK activation and cell death. Oncogene. 2016;35:1988-95 pubmed publisher
  28. Clark P, Kim R, Pober J, Kluger M. Tumor necrosis factor disrupts claudin-5 endothelial tight junction barriers in two distinct NF-κB-dependent phases. PLoS ONE. 2015;10:e0120075 pubmed publisher
  29. Opperman C, Sishi B. Tumor necrosis factor alpha stimulates p62 accumulation and enhances proteasome activity independently of ROS. Cell Biol Toxicol. 2015;31:83-94 pubmed publisher
  30. Wang Y, Tan B, Mu R, Chang Y, Wu M, Tu H, et al. Ubiquitin-associated domain-containing ubiquitin regulatory X (UBX) protein UBXN1 is a negative regulator of nuclear factor κB (NF-κB) signaling. J Biol Chem. 2015;290:10395-405 pubmed publisher
  31. Morlé A, Garrido C, Micheau O. Hyperthermia restores apoptosis induced by death receptors through aggregation-induced c-FLIP cytosolic depletion. Cell Death Dis. 2015;6:e1633 pubmed publisher
  32. Gao S, Andreeva K, Cooper N. Ischemia-reperfusion injury of the retina is linked to necroptosis via the ERK1/2-RIP3 pathway. Mol Vis. 2014;20:1374-87 pubmed
  33. Varley K, Gertz J, Roberts B, Davis N, Bowling K, Kirby M, et al. Recurrent read-through fusion transcripts in breast cancer. Breast Cancer Res Treat. 2014;146:287-97 pubmed publisher
  34. Li M, Liu Y, Xia F, Wu Z, Deng L, Jiang R, et al. Progranulin is required for proper ER stress response and inhibits ER stress-mediated apoptosis through TNFR2. Cell Signal. 2014;26:1539-48 pubmed publisher
  35. Kim T, Kang Y, Park Z, Kim Y, Hong S, Oh S, et al. SH3RF2 functions as an oncogene by mediating PAK4 protein stability. Carcinogenesis. 2014;35:624-34 pubmed publisher
  36. Luce A, Courtin A, Levalois C, Altmeyer Morel S, Romeo P, Chevillard S, et al. Death receptor pathways mediate targeted and non-targeted effects of ionizing radiations in breast cancer cells. Carcinogenesis. 2009;30:432-9 pubmed publisher