This is a Validated Antibody Database (VAD) review about rat Tial1, based on 13 published articles (read how Labome selects the articles), using Tial1 antibody in all methods. It is aimed to help Labome visitors find the most suited Tial1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Tial1 synonym: nucleolysin TIAR; RNA binding protein TIAR (TIA-1 related); Tial 1 cytotoxic granule-associated RNA- binding protein-like 1; Tial1 cytotoxic granule-associated RNA binding protein-like 1

Cell Signaling Technology
rabbit monoclonal (D32D3)
  • western blot; human; loading ...; fig 3e
Cell Signaling Technology Tial1 antibody (Cell Signalling Tech, 8509P) was used in western blot on human samples (fig 3e). Nucleic Acids Res (2018) ncbi
rabbit monoclonal (D32D3)
  • western blot; human; loading ...; fig S1
Cell Signaling Technology Tial1 antibody (Cell signaling, D32D3) was used in western blot on human samples (fig S1). Nucleic Acids Res (2017) ncbi
rabbit monoclonal (D32D3)
  • immunocytochemistry; human; fig 1
Cell Signaling Technology Tial1 antibody (Cell signaling, 8509) was used in immunocytochemistry on human samples (fig 1). PLoS Pathog (2016) ncbi
rabbit monoclonal (D32D3)
  • immunocytochemistry; human; fig 1
Cell Signaling Technology Tial1 antibody (Cell Signaling Tech, 8509) was used in immunocytochemistry on human samples (fig 1). Front Microbiol (2015) ncbi
BD Biosciences
mouse monoclonal (6/TIAR)
  • immunohistochemistry; human; loading ...; fig 1s2b
BD Biosciences Tial1 antibody (BD Biosciences, 610352) was used in immunohistochemistry on human samples (fig 1s2b). elife (2019) ncbi
mouse monoclonal (6/TIAR)
  • immunocytochemistry; human; 1:200; loading ...; fig s3f
BD Biosciences Tial1 antibody (BD Biosciences, 610352) was used in immunocytochemistry on human samples at 1:200 (fig s3f). Nature (2018) ncbi
mouse monoclonal (6/TIAR)
  • immunocytochemistry; human; 1:1000; loading ...; fig 2c
BD Biosciences Tial1 antibody (BD, 610352) was used in immunocytochemistry on human samples at 1:1000 (fig 2c). Sci Rep (2017) ncbi
mouse monoclonal (6/TIAR)
  • immunohistochemistry - paraffin section; human; 1:60; loading ...; tbl 1
In order to examine eosinophilic neuronal cytoplasmic inclusions, BD Biosciences Tial1 antibody (BD Biosciences, 6/TIAR) was used in immunohistochemistry - paraffin section on human samples at 1:60 (tbl 1). Neuropathology (2016) ncbi
mouse monoclonal (6/TIAR)
  • immunocytochemistry; human; 1:1000; fig 4
In order to study induced pluripotent stem cells derived from patients with amyotrophic lateral sclerosis, BD Biosciences Tial1 antibody (BD Biosciences, 610352) was used in immunocytochemistry on human samples at 1:1000 (fig 4). Dis Model Mech (2015) ncbi
mouse monoclonal (6/TIAR)
  • immunohistochemistry; mouse; 1:1000; fig 3
BD Biosciences Tial1 antibody (BD laboratories, 10352) was used in immunohistochemistry on mouse samples at 1:1000 (fig 3). Amyotroph Lateral Scler Frontotemporal Degener (2015) ncbi
mouse monoclonal (6/TIAR)
  • immunocytochemistry; human; 1:200; fig 6
In order to examine the methylation state of ATXN2L and its contribution to ATXN2L localization, BD Biosciences Tial1 antibody (BD Biosciences, 610352) was used in immunocytochemistry on human samples at 1:200 (fig 6). Exp Cell Res (2015) ncbi
mouse monoclonal (6/TIAR)
  • immunohistochemistry - paraffin section; human; 1:60
In order to investigate the association of eosinophilic neuronal cytoplasmic inclusions with stress granules and autophagy in two clinical cases, BD Biosciences Tial1 antibody (BD Biosciences, 6/TIAR) was used in immunohistochemistry - paraffin section on human samples at 1:60. Neuropathology (2014) ncbi
mouse monoclonal (6/TIAR)
  • immunocytochemistry; human; 1:200
BD Biosciences Tial1 antibody (BD, 610352) was used in immunocytochemistry on human samples at 1:200. Nucleic Acids Res (2014) ncbi
Articles Reviewed
  1. Zhang P, Fan B, Yang P, Temirov J, Messing J, Kim H, et al. Chronic optogenetic induction of stress granules is cytotoxic and reveals the evolution of ALS-FTD pathology. elife. 2019;8: pubmed publisher
  2. Rai A, Chen J, Selbach M, Pelkmans L. Kinase-controlled phase transition of membraneless organelles in mitosis. Nature. 2018;559:211-216 pubmed publisher
  3. Kralovicova J, Sevcikova I, Stejskalova E, Obuca M, Hiller M, Stanek D, et al. PUF60-activated exons uncover altered 3' splice-site selection by germline missense mutations in a single RRM. Nucleic Acids Res. 2018;46:6166-6187 pubmed publisher
  4. Dimasi P, Quintiero A, Shelkovnikova T, Buchman V. Modulation of p-eIF2α cellular levels and stress granule assembly/disassembly by trehalose. Sci Rep. 2017;7:44088 pubmed publisher
  5. Kralovicova J, Vorechovsky I. Alternative splicing of U2AF1 reveals a shared repression mechanism for duplicated exons. Nucleic Acids Res. 2017;45:417-434 pubmed publisher
  6. Ito M, Nakamura K, Mori F, Miki Y, Tanji K, Wakabayashi K. Novel eosinophilic neuronal cytoplasmic inclusions in the external cuneate nucleus of humans. Neuropathology. 2016;36:441-447 pubmed publisher
  7. Oh S, Onomoto K, Wakimoto M, Onoguchi K, Ishidate F, Fujiwara T, et al. Leader-Containing Uncapped Viral Transcript Activates RIG-I in Antiviral Stress Granules. PLoS Pathog. 2016;12:e1005444 pubmed publisher
  8. Yoshida A, Kawabata R, Honda T, Tomonaga K, Sakaguchi T, Irie T. IFN-β-inducing, unusual viral RNA species produced by paramyxovirus infection accumulated into distinct cytoplasmic structures in an RNA-type-dependent manner. Front Microbiol. 2015;6:804 pubmed publisher
  9. Lenzi J, De Santis R, de Turris V, Morlando M, Laneve P, Calvo A, et al. ALS mutant FUS proteins are recruited into stress granules in induced pluripotent stem cell-derived motoneurons. Dis Model Mech. 2015;8:755-66 pubmed publisher
  10. Robinson H, Deykin A, Bronovitsky E, Ovchinnikov R, Ustyugov A, Shelkovnikova T, et al. Early lethality and neuronal proteinopathy in mice expressing cytoplasm-targeted FUS that lacks the RNA recognition motif. Amyotroph Lateral Scler Frontotemporal Degener. 2015;16:402-9 pubmed publisher
  11. Kaehler C, Guenther A, Uhlich A, Krobitsch S. PRMT1-mediated arginine methylation controls ATXN2L localization. Exp Cell Res. 2015;334:114-25 pubmed publisher
  12. Mori F, Watanabe Y, Miki Y, Tanji K, Odagiri S, Eto K, et al. Ubiquitin-negative, eosinophilic neuronal cytoplasmic inclusions associated with stress granules and autophagy: an immunohistochemical investigation of two cases. Neuropathology. 2014;34:140-7 pubmed
  13. Kaehler C, Isensee J, Hucho T, Lehrach H, Krobitsch S. 5-Fluorouracil affects assembly of stress granules based on RNA incorporation. Nucleic Acids Res. 2014;42:6436-47 pubmed publisher