This is a Validated Antibody Database (VAD) review about rat Tgfbr2, based on 14 published articles (read how Labome selects the articles), using Tgfbr2 antibody in all methods. It is aimed to help Labome visitors find the most suited Tgfbr2 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Tgfbr2 synonym: TGF-beta 2; Tgfbr2T

Knockout validation
Santa Cruz Biotechnology
mouse monoclonal (D-2)
  • western blot knockout validation; human; 1:1000; loading ...; fig 5e
Santa Cruz Biotechnology Tgfbr2 antibody (Santa Cruz, sc-17799) was used in western blot knockout validation on human samples at 1:1000 (fig 5e). Nat Commun (2021) ncbi
Santa Cruz Biotechnology
mouse monoclonal (C-4)
  • immunohistochemistry - paraffin section; mouse; 1:100; loading ...; fig 7a
Santa Cruz Biotechnology Tgfbr2 antibody (Santa Cruz, sc-17791) was used in immunohistochemistry - paraffin section on mouse samples at 1:100 (fig 7a). Mol Med Rep (2022) ncbi
mouse monoclonal (D-2)
  • western blot knockout validation; human; 1:1000; loading ...; fig 5e
Santa Cruz Biotechnology Tgfbr2 antibody (Santa Cruz, sc-17799) was used in western blot knockout validation on human samples at 1:1000 (fig 5e). Nat Commun (2021) ncbi
mouse monoclonal (D-2)
  • western blot; mouse; 1:300; loading ...; fig 5a, 5c
  • western blot; human; 1:1000; loading ...; fig 5a
Santa Cruz Biotechnology Tgfbr2 antibody (Santa Cruz, sc-17799) was used in western blot on mouse samples at 1:300 (fig 5a, 5c) and in western blot on human samples at 1:1000 (fig 5a). J Biol Chem (2021) ncbi
mouse monoclonal (E-6)
  • western blot; human; 1:500; fig 4
In order to examine TGFBR1 and TGFBR2 mutations in human vemurafenib-induced skin lesions and in sporadic cutaneous squamous cell carcinoma, Santa Cruz Biotechnology Tgfbr2 antibody (Santa Cruz, 17792) was used in western blot on human samples at 1:500 (fig 4). Nat Commun (2016) ncbi
mouse monoclonal (D-2)
  • western blot; human; 1:500
Santa Cruz Biotechnology Tgfbr2 antibody (Santa Cruz, sc-17799) was used in western blot on human samples at 1:500. PLoS ONE (2015) ncbi
mouse monoclonal (E-6)
  • western blot; human; fig s2
Santa Cruz Biotechnology Tgfbr2 antibody (Santa Cruz, sc-17792) was used in western blot on human samples (fig s2). Sci Rep (2015) ncbi
mouse monoclonal (D-2)
  • western blot; human; fig s3
Santa Cruz Biotechnology Tgfbr2 antibody (santa Cruz, sc-17799) was used in western blot on human samples (fig s3). Oncotarget (2015) ncbi
mouse monoclonal (C-4)
  • western blot; human; fig 3
Santa Cruz Biotechnology Tgfbr2 antibody (Santa Cruz, Sc-17791) was used in western blot on human samples (fig 3). Sci Rep (2015) ncbi
mouse monoclonal (E-6)
  • western blot; human; fig 2
Santa Cruz Biotechnology Tgfbr2 antibody (Santa Cruz Biotechnology, sc-17792) was used in western blot on human samples (fig 2). FASEB J (2014) ncbi
Abcam
domestic rabbit polyclonal
  • western blot; human; 1:2000; loading ...; fig 5c
Abcam Tgfbr2 antibody (Abcam, ab186838) was used in western blot on human samples at 1:2000 (fig 5c). Int J Oncol (2021) ncbi
domestic rabbit polyclonal
  • immunohistochemistry; human; loading ...; fig 4a
  • western blot; human; loading ...; fig 4c
Abcam Tgfbr2 antibody (Abcam, ab186838) was used in immunohistochemistry on human samples (fig 4a) and in western blot on human samples (fig 4c). Front Oncol (2020) ncbi
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig 5c
Abcam Tgfbr2 antibody (Abcam, ab186838) was used in western blot on mouse samples (fig 5c). Proc Natl Acad Sci U S A (2019) ncbi
Invitrogen
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig 6j
Invitrogen Tgfbr2 antibody (Invitrogen, PA5-36115) was used in western blot on mouse samples (fig 6j). Sci Adv (2021) ncbi
MilliporeSigma
domestic rabbit polyclonal
  • western blot; human; 1:2500; loading ...; fig 4a
MilliporeSigma Tgfbr2 antibody (Sigma-Aldrich, SAB4504269) was used in western blot on human samples at 1:2500 (fig 4a). Mol Med Rep (2018) ncbi
Articles Reviewed
  1. Yeh C, Liu H, Lee M, Leu Y, Chiang W, Chang H, et al. Phytochemical‑rich herbal formula ATG‑125 protects against sucrose‑induced gastrocnemius muscle atrophy by rescuing Akt signaling and improving mitochondrial dysfunction in young adult mice. Mol Med Rep. 2022;25: pubmed publisher
  2. Xi Y, Li Y, Xu P, Li S, Liu Z, Tung H, et al. The anti-fibrotic drug pirfenidone inhibits liver fibrosis by targeting the small oxidoreductase glutaredoxin-1. Sci Adv. 2021;7:eabg9241 pubmed publisher
  3. Huang J, Xiao R, Wang X, Khadka B, Fang Z, Yu M, et al. MicroRNA‑93 knockdown inhibits acute myeloid leukemia cell growth via inactivating the PI3K/AKT pathway by upregulating DAB2. Int J Oncol. 2021;59: pubmed publisher
  4. Bruce J, To K, Lui V, Chung G, Chan Y, Tsang C, et al. Whole-genome profiling of nasopharyngeal carcinoma reveals viral-host co-operation in inflammatory NF-κB activation and immune escape. Nat Commun. 2021;12:4193 pubmed publisher
  5. Pan Y, Iejima D, Nakayama M, Suga A, Noda T, Kaur I, et al. Binding of Gtf2i-β/δ transcription factors to the ARMS2 gene leads to increased circulating HTRA1 in AMD patients and in vitro. J Biol Chem. 2021;296:100456 pubmed publisher
  6. Fu X, Qie J, Fu Q, Chen J, Jin Y, Ding Z. miR-20a-5p/TGFBR2 Axis Affects Pro-inflammatory Macrophages and Aggravates Liver Fibrosis. Front Oncol. 2020;10:107 pubmed publisher
  7. Wang W, Chun H, Baek J, Sadik J, Shirazyan A, Razavi P, et al. The TGFβ type I receptor TGFβRI functions as an inhibitor of BMP signaling in cartilage. Proc Natl Acad Sci U S A. 2019;116:15570-15579 pubmed publisher
  8. Li T, Zhao J. Knockdown of elF3a inhibits TGF??1?induced extracellular matrix protein expression in keloid fibroblasts. Mol Med Rep. 2018;17:4057-4061 pubmed publisher
  9. Cammareri P, Rose A, Vincent D, Wang J, Nagano A, Libertini S, et al. Inactivation of TGFβ receptors in stem cells drives cutaneous squamous cell carcinoma. Nat Commun. 2016;7:12493 pubmed publisher
  10. Lee J, Fricke F, Warnken U, Schnölzer M, Kopitz J, Gebert J. Reconstitution of TGFBR2-Mediated Signaling Causes Upregulation of GDF-15 in HCT116 Colorectal Cancer Cells. PLoS ONE. 2015;10:e0131506 pubmed publisher
  11. Rojas Fernandez A, Herhaus L, MacArtney T, Lachaud C, Hay R, Sapkota G. Rapid generation of endogenously driven transcriptional reporters in cells through CRISPR/Cas9. Sci Rep. 2015;5:9811 pubmed publisher
  12. Uppal A, Wightman S, Mallon S, Oshima G, Pitroda S, Zhang Q, et al. 14q32-encoded microRNAs mediate an oligometastatic phenotype. Oncotarget. 2015;6:3540-52 pubmed
  13. Rao R, Dhele N, Cheemadan S, Ketkar A, Jayandharan G, Palakodeti D, et al. Ezh2 mediated H3K27me3 activity facilitates somatic transition during human pluripotent reprogramming. Sci Rep. 2015;5:8229 pubmed publisher
  14. Holtzhausen A, Golzio C, How T, Lee Y, Schiemann W, Katsanis N, et al. Novel bone morphogenetic protein signaling through Smad2 and Smad3 to regulate cancer progression and development. FASEB J. 2014;28:1248-67 pubmed publisher