This is a Validated Antibody Database (VAD) review about rat Tbx21, based on 12 published articles (read how Labome selects the articles), using Tbx21 antibody in all methods. It is aimed to help Labome visitors find the most suited Tbx21 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Tbx21 synonym: T-box transcription factor TBX21

Knockout validation
Santa Cruz Biotechnology
mouse monoclonal (4B10)
  • western blot knockout validation; mouse; 1:100; loading ...; fig 1b
In order to elucidate the role of Tbet in acute lung injury, Santa Cruz Biotechnology Tbx21 antibody (Santa Cruz, sc-21749) was used in western blot knockout validation on mouse samples at 1:100 (fig 1b). J Leukoc Biol (2017) ncbi
Santa Cruz Biotechnology
mouse monoclonal (4B10)
  • flow cytometry; mouse; fig s3b
In order to investigate the mechanisms by which eomesodermin regulates memory fitness in T cells, Santa Cruz Biotechnology Tbx21 antibody (Santa Cruz, 4B10) was used in flow cytometry on mouse samples (fig s3b). Proc Natl Acad Sci U S A (2017) ncbi
mouse monoclonal (4B10)
  • immunoprecipitation; mouse; fig 6f
  • western blot; mouse; fig 6f
In order to characterize Aire-mediated signaling in medullary thymic epithelial cells, Santa Cruz Biotechnology Tbx21 antibody (SantaCruz, 4B10) was used in immunoprecipitation on mouse samples (fig 6f) and in western blot on mouse samples (fig 6f). Nat Immunol (2017) ncbi
mouse monoclonal (4B10)
  • western blot knockout validation; mouse; 1:100; loading ...; fig 1b
In order to elucidate the role of Tbet in acute lung injury, Santa Cruz Biotechnology Tbx21 antibody (Santa Cruz, sc-21749) was used in western blot knockout validation on mouse samples at 1:100 (fig 1b). J Leukoc Biol (2017) ncbi
mouse monoclonal (4B10)
  • flow cytometry; mouse; loading ...; fig 2f
In order to propose that the ERK-AP-1 axis is important for translating TCR signal strength into proportional activation of downstream events, Santa Cruz Biotechnology Tbx21 antibody (SantaCruz, SC-21749) was used in flow cytometry on mouse samples (fig 2f). elife (2016) ncbi
mouse monoclonal (4B10)
  • western blot; mouse; 1:200; fig 4
Santa Cruz Biotechnology Tbx21 antibody (Santa Cruz, 4B10) was used in western blot on mouse samples at 1:200 (fig 4). PLoS ONE (2015) ncbi
mouse monoclonal (4B10)
  • flow cytometry; mouse; fig 8
Santa Cruz Biotechnology Tbx21 antibody (Santa Cruz, 4B10) was used in flow cytometry on mouse samples (fig 8). J Immunol (2015) ncbi
mouse monoclonal (4B10)
  • chromatin immunoprecipitation; human; loading ...; fig 4f
  • western blot; human; loading ...; fig 4c
Santa Cruz Biotechnology Tbx21 antibody (Santa Cruz Biotechnology, 4B10) was used in chromatin immunoprecipitation on human samples (fig 4f) and in western blot on human samples (fig 4c). Am J Pathol (2015) ncbi
mouse monoclonal (4B10)
  • immunohistochemistry; human; 1:100
Santa Cruz Biotechnology Tbx21 antibody (SANTA CRUZ, 4B10) was used in immunohistochemistry on human samples at 1:100. BMC Clin Pathol (2014) ncbi
mouse monoclonal (4B10)
  • chromatin immunoprecipitation; mouse
Santa Cruz Biotechnology Tbx21 antibody (Santa Cruz, sc-21749) was used in chromatin immunoprecipitation on mouse samples . J Immunol (2014) ncbi
mouse monoclonal (4B10)
  • western blot; mouse
Santa Cruz Biotechnology Tbx21 antibody (Santa Cruz Biotechnology, sc-21749) was used in western blot on mouse samples . J Immunol (2014) ncbi
mouse monoclonal (4B10)
  • western blot; mouse; fig 1
In order to examine how IL-2-signaling regulates the Bcl-6-Blimp-1 axis in Th1 cells, Santa Cruz Biotechnology Tbx21 antibody (Santa Cruz, 4B10) was used in western blot on mouse samples (fig 1). Nat Immunol (2012) ncbi
Invitrogen
mouse monoclonal (eBio39D (39D, 3-9D))
  • flow cytometry; human
In order to use semantic connectivity maps to find biomarkers for multiple sclerosis, Invitrogen Tbx21 antibody (eBioscience, 39D) was used in flow cytometry on human samples . Immun Ageing (2013) ncbi
Articles Reviewed
  1. Knudson K, Pritzl C, Saxena V, Altman A, Daniels M, Teixeiro E. NFκB-Pim-1-Eomesodermin axis is critical for maintaining CD8 T-cell memory quality. Proc Natl Acad Sci U S A. 2017;114:E1659-E1667 pubmed publisher
  2. Herzig Y, Nevo S, Bornstein C, Brezis M, Ben Hur S, Shkedy A, et al. Transcriptional programs that control expression of the autoimmune regulator gene Aire. Nat Immunol. 2017;18:161-172 pubmed publisher
  3. Hoegl S, Ehrentraut H, Brodsky K, Victorino F, Golden Mason L, Eltzschig H, et al. NK cells regulate CXCR2+ neutrophil recruitment during acute lung injury. J Leukoc Biol. 2017;101:471-480 pubmed publisher
  4. Allison K, Sajti E, Collier J, Gosselin D, Troutman T, Stone E, et al. Affinity and dose of TCR engagement yield proportional enhancer and gene activity in CD4+ T cells. elife. 2016;5: pubmed publisher
  5. Castiglioni A, Corna G, Rigamonti E, Basso V, Vezzoli M, Monno A, et al. FOXP3+ T Cells Recruited to Sites of Sterile Skeletal Muscle Injury Regulate the Fate of Satellite Cells and Guide Effective Tissue Regeneration. PLoS ONE. 2015;10:e0128094 pubmed publisher
  6. Pei B, Zhao M, Miller B, Véla J, Bruinsma M, Virgin H, et al. Invariant NKT cells require autophagy to coordinate proliferation and survival signals during differentiation. J Immunol. 2015;194:5872-84 pubmed publisher
  7. Chen H, Huang W, Yang L, Lin C. The PTEN-AKT-mTOR/RICTOR Pathway in Nasal Natural Killer Cell Lymphoma Is Activated by miR-494-3p via PTEN But Inhibited by miR-142-3p via RICTOR. Am J Pathol. 2015;185:1487-99 pubmed publisher
  8. Perino G, Ricciardi B, Jerabek S, Martignoni G, Wilner G, Maass D, et al. Implant based differences in adverse local tissue reaction in failed total hip arthroplasties: a morphological and immunohistochemical study. BMC Clin Pathol. 2014;14:39 pubmed publisher
  9. Collier S, Henderson M, Tossberg J, Aune T. Regulation of the Th1 genomic locus from Ifng through Tmevpg1 by T-bet. J Immunol. 2014;193:3959-65 pubmed publisher
  10. Tong Q, He S, Xie F, Mochizuki K, Liu Y, Mochizuki I, et al. Ezh2 regulates transcriptional and posttranslational expression of T-bet and promotes Th1 cell responses mediating aplastic anemia in mice. J Immunol. 2014;192:5012-22 pubmed publisher
  11. Gironi M, Saresella M, Rovaris M, Vaghi M, Nemni R, Clerici M, et al. A novel data mining system points out hidden relationships between immunological markers in multiple sclerosis. Immun Ageing. 2013;10:1 pubmed publisher
  12. Oestreich K, Mohn S, Weinmann A. Molecular mechanisms that control the expression and activity of Bcl-6 in TH1 cells to regulate flexibility with a TFH-like gene profile. Nat Immunol. 2012;13:405-11 pubmed publisher