This is a Validated Antibody Database (VAD) review about rat Syt1, based on 20 published articles (read how Labome selects the articles), using Syt1 antibody in all methods. It is aimed to help Labome visitors find the most suited Syt1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Syt1 synonym: P65

Synaptic Systems
domestic rabbit polyclonal
  • immunocytochemistry; rat; loading ...
Synaptic Systems Syt1 antibody (Synaptic Systems, 105103C5) was used in immunocytochemistry on rat samples . Sci Adv (2021) ncbi
domestic rabbit polyclonal
  • immunocytochemistry; mouse; loading ...; fig s6c
Synaptic Systems Syt1 antibody (Synaptic Systems, 105 103C3) was used in immunocytochemistry on mouse samples (fig s6c). Neuron (2021) ncbi
mouse monoclonal (41.1)
  • immunohistochemistry - frozen section; mouse; loading ...; fig s1f
  • western blot; mouse; loading ...; fig s6b
Synaptic Systems Syt1 antibody (Synaptic Systems, 105 011C5) was used in immunohistochemistry - frozen section on mouse samples (fig s1f) and in western blot on mouse samples (fig s6b). Neuron (2021) ncbi
guinea-pigs polyclonal
  • immunohistochemistry; mouse; 1:1000; loading ...
Synaptic Systems Syt1 antibody (Synaptic Systems, 105 105) was used in immunohistochemistry on mouse samples at 1:1000. Physiol Rep (2020) ncbi
mouse monoclonal (41.1)
  • immunocytochemistry; human; loading ...; fig s1e
Synaptic Systems Syt1 antibody (Synaptic Systems, 105 011C2) was used in immunocytochemistry on human samples (fig s1e). Cell (2019) ncbi
mouse monoclonal (41.1)
  • western blot; bovine; fig s1
Synaptic Systems Syt1 antibody (Synaptic Systems, 41.1) was used in western blot on bovine samples (fig s1). Sci Rep (2017) ncbi
guinea-pigs polyclonal
  • western blot; rat; 1:500; loading ...; fig 5b
In order to develop methods to study vesicle-associated proteins and exocytosis in stellate astrocytes, Synaptic Systems Syt1 antibody (Synaptic Systems, 105105) was used in western blot on rat samples at 1:500 (fig 5b). J Gen Physiol (2017) ncbi
mouse monoclonal (604.2)
  • immunocytochemistry; rat; 1:400; fig 2
Synaptic Systems Syt1 antibody (Synaptic System, 105 311C3) was used in immunocytochemistry on rat samples at 1:400 (fig 2). Sci Rep (2016) ncbi
mouse monoclonal (41.1)
  • western blot; mouse; 1:1000; loading ...; fig 3a
In order to investigate the function of extended synaptotagmins in knock out mice, Synaptic Systems Syt1 antibody (Synaptic systems, 41.1) was used in western blot on mouse samples at 1:1000 (fig 3a). PLoS ONE (2016) ncbi
mouse monoclonal (604.1)
  • western blot; rat; fig 1
In order to characterize inhibition of clathrin-mediated and bulk endocytosis by synaptotagmin-11, Synaptic Systems Syt1 antibody (Synaptic Systems, 105221) was used in western blot on rat samples (fig 1). EMBO Rep (2016) ncbi
mouse monoclonal (604.2)
  • immunocytochemistry; rat
In order to study the dynamics and regulation of neurexin trafficking, Synaptic Systems Syt1 antibody (SynapticSystems, 105311CpH) was used in immunocytochemistry on rat samples . J Neurosci (2015) ncbi
Abcam
mouse monoclonal (ASV30)
  • western blot; mouse; loading ...; fig 4p
Abcam Syt1 antibody (Abcam, ab13259) was used in western blot on mouse samples (fig 4p). EBioMedicine (2022) ncbi
mouse monoclonal (ASV30)
  • immunocytochemistry; rat; loading ...
Abcam Syt1 antibody (Abcam, ab13259) was used in immunocytochemistry on rat samples . Sci Adv (2021) ncbi
mouse monoclonal (ASV30)
  • western blot; rat; 1:1000; loading ...; fig 2f
Abcam Syt1 antibody (Abcam, ab13259) was used in western blot on rat samples at 1:1000 (fig 2f). Aging Cell (2020) ncbi
mouse monoclonal (ASV30)
  • immunocytochemistry; mouse; 1:500; loading ...; fig 2b
Abcam Syt1 antibody (Abcam, ab13259) was used in immunocytochemistry on mouse samples at 1:500 (fig 2b). J Immunol Methods (2017) ncbi
mouse monoclonal (ASV30)
  • immunohistochemistry; rat; 1:100; fig 5
In order to utilize a system for neuromuscular junction development and maintenance to study mechanisms, Abcam Syt1 antibody (Abcam, ab13259) was used in immunohistochemistry on rat samples at 1:100 (fig 5). Development (2016) ncbi
Invitrogen
mouse monoclonal (ASV30)
  • immunoprecipitation; mouse; fig 4b
  • western blot; mouse; fig 3b
In order to study the activity-driven interaction between presenilin 1 and synaptotagmin 1 and links to calcium, amyloid beta, and synapse, Invitrogen Syt1 antibody (Pierce, MA125568) was used in immunoprecipitation on mouse samples (fig 4b) and in western blot on mouse samples (fig 3b). BMC Biol (2016) ncbi
mouse monoclonal (ASV30)
  • immunocytochemistry; rat; fig 3
  • western blot; hamsters; 1:1000; fig 2
In order to assess the interaction of APP with synaptotagmins that promotes A-beta generation, Invitrogen Syt1 antibody (Thermo Fisher, ASV30) was used in immunocytochemistry on rat samples (fig 3) and in western blot on hamsters samples at 1:1000 (fig 2). Mol Neurodegener (2015) ncbi
Santa Cruz Biotechnology
mouse monoclonal (41)
  • western blot; human; loading ...; fig 2a
Santa Cruz Biotechnology Syt1 antibody (Santa Cruz, sc-136088) was used in western blot on human samples (fig 2a). Toxicol Lett (2015) ncbi
Developmental Studies Hybridoma Bank
mouse monoclonal (mAB 30 (asv30))
  • western blot; mouse; 1:50; loading ...; fig s6a
Developmental Studies Hybridoma Bank Syt1 antibody (DSHB, mAB30) was used in western blot on mouse samples at 1:50 (fig s6a). Proc Natl Acad Sci U S A (2018) ncbi
mouse monoclonal (mAB 30 (asv30))
  • immunohistochemistry; mouse; 1:100; fig 8
Developmental Studies Hybridoma Bank Syt1 antibody (DSHB, 30) was used in immunohistochemistry on mouse samples at 1:100 (fig 8). Nat Commun (2015) ncbi
MilliporeSigma
domestic rabbit polyclonal
  • immunocytochemistry; rat; loading ...; fig 3
In order to study the role of astrocytes to Alzheimer's disease, MilliporeSigma Syt1 antibody (Sigma, SAB4502907) was used in immunocytochemistry on rat samples (fig 3). J Alzheimers Dis (2016) ncbi
Articles Reviewed
  1. Zhou Q, Li S, Li M, Ke D, Wang Q, Yang Y, et al. Human tau accumulation promotes glycogen synthase kinase-3β acetylation and thus upregulates the kinase: A vicious cycle in Alzheimer neurodegeneration. EBioMedicine. 2022;78:103970 pubmed publisher
  2. Ivanova D, Dobson K, Gajbhiye A, Davenport E, Hacker D, Ultanir S, et al. Control of synaptic vesicle release probability via VAMP4 targeting to endolysosomes. Sci Adv. 2021;7: pubmed publisher
  3. Kuijpers M, Kochlamazashvili G, Stumpf A, Puchkov D, Swaminathan A, Lucht M, et al. Neuronal Autophagy Regulates Presynaptic Neurotransmission by Controlling the Axonal Endoplasmic Reticulum. Neuron. 2021;109:299-313.e9 pubmed publisher
  4. Arias Hervert E, Xu N, Njus M, Murphy G, Hou Y, Williams J, et al. Actions of Rab27B-GTPase on mammalian central excitatory synaptic transmission. Physiol Rep. 2020;8:e14428 pubmed publisher
  5. Ye J, Yin Y, Liu H, Fang L, Tao X, Wei L, et al. Tau inhibits PKA by nuclear proteasome-dependent PKAR2α elevation with suppressed CREB/GluA1 phosphorylation. Aging Cell. 2020;19:e13055 pubmed publisher
  6. Patzke C, Brockmann M, Dai J, Gan K, Grauel M, Fenske P, et al. Neuromodulator Signaling Bidirectionally Controls Vesicle Numbers in Human Synapses. Cell. 2019;179:498-513.e22 pubmed publisher
  7. Wang Y, Figueiredo D, Sun X, Dong Z, Chen W, Cui W, et al. Controlling of glutamate release by neuregulin3 via inhibiting the assembly of the SNARE complex. Proc Natl Acad Sci U S A. 2018;115:2508-2513 pubmed publisher
  8. Yadirgi G, Stickings P, Rajagopal S, Liu Y, Sesardic D. Immuno-detection of cleaved SNAP-25 from differentiated mouse embryonic stem cells provides a sensitive assay for determination of botulinum A toxin and antitoxin potency. J Immunol Methods. 2017;451:90-99 pubmed publisher
  9. Gümürdü A, Yildiz R, Eren E, Karakülah G, Unver T, Genc S, et al. MicroRNA exocytosis by large dense-core vesicle fusion. Sci Rep. 2017;7:45661 pubmed publisher
  10. Wolfes A, Ahmed S, Awasthi A, Stahlberg M, Rajput A, Magruder D, et al. A novel method for culturing stellate astrocytes reveals spatially distinct Ca2+ signaling and vesicle recycling in astrocytic processes. J Gen Physiol. 2017;149:149-170 pubmed publisher
  11. Hu H, Umemori H, Hsueh Y. Postsynaptic SDC2 induces transsynaptic signaling via FGF22 for bidirectional synaptic formation. Sci Rep. 2016;6:33592 pubmed publisher
  12. Li Y, Chang L, Song Y, Gao X, Roselli F, Liu J, et al. Astrocytic GluN2A and GluN2B Oppose the Synaptotoxic Effects of Amyloid-?1-40 in Hippocampal Cells. J Alzheimers Dis. 2016;54:135-48 pubmed publisher
  13. Sclip A, Bacaj T, Giam L, Sudhof T. Extended Synaptotagmin (ESyt) Triple Knock-Out Mice Are Viable and Fertile without Obvious Endoplasmic Reticulum Dysfunction. PLoS ONE. 2016;11:e0158295 pubmed publisher
  14. Vilmont V, Cadot B, Ouanounou G, Gomes E. A system for studying mechanisms of neuromuscular junction development and maintenance. Development. 2016;143:2464-77 pubmed publisher
  15. Kuzuya A, Zoltowska K, Post K, Arimon M, Li X, Svirsky S, et al. Identification of the novel activity-driven interaction between synaptotagmin 1 and presenilin 1 links calcium, synapse, and amyloid beta. BMC Biol. 2016;14:25 pubmed publisher
  16. Wang C, Wang Y, Hu M, Chai Z, Wu Q, Huang R, et al. Synaptotagmin-11 inhibits clathrin-mediated and bulk endocytosis. EMBO Rep. 2016;17:47-63 pubmed publisher
  17. Neupert C, Schneider R, Klatt O, Reissner C, Repetto D, Biermann B, et al. Regulated Dynamic Trafficking of Neurexins Inside and Outside of Synaptic Terminals. J Neurosci. 2015;35:13629-47 pubmed publisher
  18. Gautam V, D Avanzo C, Berezovska O, Tanzi R, Kovacs D. Synaptotagmins interact with APP and promote Aβ generation. Mol Neurodegener. 2015;10:31 pubmed publisher
  19. Chiou Y, Liou S, Wong R, Chen C, Lee H. Nickel may contribute to EGFR mutation and synergistically promotes tumor invasion in EGFR-mutated lung cancer via nickel-induced microRNA-21 expression. Toxicol Lett. 2015;237:46-54 pubmed publisher
  20. Adams K, Rousso D, Umbach J, Novitch B. Foxp1-mediated programming of limb-innervating motor neurons from mouse and human embryonic stem cells. Nat Commun. 2015;6:6778 pubmed publisher