This is a Validated Antibody Database (VAD) review about rat Sympk, based on 4 published articles (read how Labome selects the articles), using Sympk antibody in all methods. It is aimed to help Labome visitors find the most suited Sympk antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Sympk synonym: Hfn3g; symplekin; hepatocyte nuclear factor 3 gamma

Abcam
rabbit polyclonal
  • western blot; mouse; fig 4
In order to propose that a special mechanism of splicing occurs in the testis and brain whereby H2A.B.3 recruits RNA processing factors from splicing speckles, Abcam Sympk antibody (Abcam, ab80274) was used in western blot on mouse samples (fig 4). PLoS Genet (2017) ncbi
BD Biosciences
mouse monoclonal (25/Symplekin)
  • immunocytochemistry; human; loading ...; fig 1a
In order to study the effect of symplekin on cellular proliferation and dedifferentiation, BD Biosciences Sympk antibody (BD Biosciences, 610644) was used in immunocytochemistry on human samples (fig 1a). Sci Rep (2017) ncbi
mouse monoclonal (25/Symplekin)
  • western blot; human; loading ...; fig 6b
BD Biosciences Sympk antibody (BD Transduction Laboratories, 610644) was used in western blot on human samples (fig 6b). elife (2016) ncbi
mouse monoclonal (25/Symplekin)
  • western blot; human
In order to investigate the role of nuclear ARVCF protein during alternative splicing, BD Biosciences Sympk antibody (BD Biosciences, 610644) was used in western blot on human samples . J Biol Chem (2014) ncbi
Articles Reviewed
  1. Zhang C, Mao H, Cao Y. Nuclear accumulation of symplekin promotes cellular proliferation and dedifferentiation in an ERK1/2-dependent manner. Sci Rep. 2017;7:3769 pubmed publisher
  2. Soboleva T, Parker B, Nekrasov M, Hart Smith G, Tay Y, Tng W, et al. A new link between transcriptional initiation and pre-mRNA splicing: The RNA binding histone variant H2A.B. PLoS Genet. 2017;13:e1006633 pubmed publisher
  3. Guillén Boixet J, Buzon V, Salvatella X, Mendez R. CPEB4 is regulated during cell cycle by ERK2/Cdk1-mediated phosphorylation and its assembly into liquid-like droplets. elife. 2016;5: pubmed publisher
  4. Rappe U, Schlechter T, Aschoff M, Hotz Wagenblatt A, Hofmann I. Nuclear ARVCF protein binds splicing factors and contributes to the regulation of alternative splicing. J Biol Chem. 2014;289:12421-34 pubmed publisher