This is a Validated Antibody Database (VAD) review about rat Srsf2, based on 36 published articles (read how Labome selects the articles), using Srsf2 antibody in all methods. It is aimed to help Labome visitors find the most suited Srsf2 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Srsf2 synonym: Sfrs2

Abcam
mouse monoclonal (SC-35)
  • immunocytochemistry; human; loading ...; fig 3a
Abcam Srsf2 antibody (Abcam, ab11826) was used in immunocytochemistry on human samples (fig 3a). Nature (2020) ncbi
mouse monoclonal (SC-35)
  • western blot; human; 1:1000; loading ...; fig 2c
Abcam Srsf2 antibody (Abcam, ab11826) was used in western blot on human samples at 1:1000 (fig 2c). Nat Commun (2019) ncbi
mouse monoclonal (SC-35)
  • immunocytochemistry; human; 1:50; loading ...; fig s5a
Abcam Srsf2 antibody (Abcam, ab11826) was used in immunocytochemistry on human samples at 1:50 (fig s5a). Nat Commun (2018) ncbi
mouse monoclonal (SC-35)
  • immunocytochemistry; human; 1:300; loading ...; fig s2c
In order to study the function of SAF-A in interphase chromosome structure integrity and its mechanism, Abcam Srsf2 antibody (Abcam, ab11826) was used in immunocytochemistry on human samples at 1:300 (fig s2c). Cell (2017) ncbi
mouse monoclonal (SC-35)
  • immunohistochemistry - frozen section; mouse; 1:500; fig 5a
Abcam Srsf2 antibody (Abcam, ab11826) was used in immunohistochemistry - frozen section on mouse samples at 1:500 (fig 5a). Dis Model Mech (2017) ncbi
mouse monoclonal (SC-35)
  • immunocytochemistry; human; 1:100; fig 2
In order to investigate the impact of serine-arginine rich splicing factor 2 mutations to myelodysplastic syndrome, Abcam Srsf2 antibody (Abcam, ab11826) was used in immunocytochemistry on human samples at 1:100 (fig 2). BMC Mol Biol (2016) ncbi
mouse monoclonal (SC-35)
  • immunocytochemistry; mouse; 1:250; fig 2
Abcam Srsf2 antibody (Abcam, ab11826) was used in immunocytochemistry on mouse samples at 1:250 (fig 2). EMBO J (2016) ncbi
mouse monoclonal (SC-35)
  • immunohistochemistry - paraffin section; human; 1:1500; loading ...; tbl s2
In order to explore the relationship between hnRNP A1 and RON tumoral expression, Abcam Srsf2 antibody (Abcam, SC-35) was used in immunohistochemistry - paraffin section on human samples at 1:1500 (tbl s2). Oncotarget (2016) ncbi
mouse monoclonal (SC-35)
  • immunocytochemistry; human; fig 3
  • western blot; human; fig 3
Abcam Srsf2 antibody (Abcam, ab11826) was used in immunocytochemistry on human samples (fig 3) and in western blot on human samples (fig 3). Front Immunol (2015) ncbi
mouse monoclonal (SC-35)
  • immunocytochemistry; African green monkey; 1:1000
In order to research the inhibition of the growth arrest activity of C/EBPalpha requiring the glutamin-alanine repeat domain of TCERG1, Abcam Srsf2 antibody (abcam, ab11826) was used in immunocytochemistry on African green monkey samples at 1:1000. J Cell Biochem (2016) ncbi
mouse monoclonal (SC-35)
  • immunohistochemistry - paraffin section; human; loading ...; fig 3
Abcam Srsf2 antibody (Abcam, ab11826) was used in immunohistochemistry - paraffin section on human samples (fig 3). Acta Neuropathol (2015) ncbi
mouse monoclonal (SC-35)
  • western blot; mouse; 1:200
Abcam Srsf2 antibody (Abcam, ab11826) was used in western blot on mouse samples at 1:200. Dev Biol (2015) ncbi
mouse monoclonal (SC-35)
  • immunocytochemistry; human
Abcam Srsf2 antibody (Abcam, ab11826) was used in immunocytochemistry on human samples . J Neurochem (2014) ncbi
mouse monoclonal (SC-35)
  • immunohistochemistry; human
Abcam Srsf2 antibody (Abcam, ab11826) was used in immunohistochemistry on human samples . PLoS ONE (2014) ncbi
mouse monoclonal (SC-35)
  • immunocytochemistry; human
Abcam Srsf2 antibody (Abcam, ab11826) was used in immunocytochemistry on human samples . J Mol Cell Biol (2014) ncbi
mouse monoclonal (SC-35)
  • immunohistochemistry - paraffin section; human
Abcam Srsf2 antibody (Abcam, ab11826) was used in immunohistochemistry - paraffin section on human samples . Brain (2014) ncbi
mouse monoclonal (SC-35)
  • immunocytochemistry; human; 1:200
Abcam Srsf2 antibody (Abcam, Ab11826) was used in immunocytochemistry on human samples at 1:200. PLoS ONE (2013) ncbi
mouse monoclonal (SC-35)
  • immunohistochemistry - frozen section; human; 1:300
  • immunohistochemistry - paraffin section; human; 1:300
Abcam Srsf2 antibody (Abcam, ab11826) was used in immunohistochemistry - frozen section on human samples at 1:300 and in immunohistochemistry - paraffin section on human samples at 1:300. PLoS ONE (2013) ncbi
mouse monoclonal (SC-35)
  • immunocytochemistry; human; 1:1000
Abcam Srsf2 antibody (Abcam, ab11826) was used in immunocytochemistry on human samples at 1:1000. J Virol (2013) ncbi
mouse monoclonal (SC-35)
  • immunocytochemistry; human
Abcam Srsf2 antibody (Abcam, ab11826) was used in immunocytochemistry on human samples . Biochem J (2013) ncbi
mouse monoclonal (SC-35)
  • immunocytochemistry; mouse
Abcam Srsf2 antibody (Abcam, ab11826) was used in immunocytochemistry on mouse samples . Nucleic Acids Res (2013) ncbi
mouse monoclonal (SC-35)
  • western blot; human
Abcam Srsf2 antibody (Abcam, ab11826) was used in western blot on human samples . FEBS Lett (2013) ncbi
Santa Cruz Biotechnology
mouse monoclonal (SC-35)
  • immunocytochemistry; human
In order to study the mechanism for RNA splicing and termination factor recruitment to RNA polymerase II in vivo, Santa Cruz Biotechnology Srsf2 antibody (Santa Cruz, sc53518) was used in immunocytochemistry on human samples . Nucleic Acids Res (2013) ncbi
MilliporeSigma
mouse monoclonal (SC-35)
  • western blot; mouse; 1:500; loading ...; fig 2e
MilliporeSigma Srsf2 antibody (Sigma-Aldrich, S4045) was used in western blot on mouse samples at 1:500 (fig 2e). Mol Psychiatry (2018) ncbi
mouse monoclonal (SC-35)
  • immunocytochemistry; human; 1:400; loading ...; fig 2a
MilliporeSigma Srsf2 antibody (Sigma-Aldrich, S4045) was used in immunocytochemistry on human samples at 1:400 (fig 2a). Nature (2018) ncbi
mouse monoclonal (SC-35)
  • immunohistochemistry - paraffin section; human; loading ...; fig 1e
  • immunocytochemistry; human; loading ...; fig 2b
In order to study factors that influence the localization of casein kinase 1, MilliporeSigma Srsf2 antibody (Sigma, S4045) was used in immunohistochemistry - paraffin section on human samples (fig 1e) and in immunocytochemistry on human samples (fig 2b). Sci Rep (2016) ncbi
mouse monoclonal (SC-35)
  • immunocytochemistry; human; 1:5000; fig 1
MilliporeSigma Srsf2 antibody (Sigma, S4045) was used in immunocytochemistry on human samples at 1:5000 (fig 1). PLoS ONE (2016) ncbi
mouse monoclonal (SC-35)
  • immunocytochemistry; human; fig s2
MilliporeSigma Srsf2 antibody (Sigma, S4045) was used in immunocytochemistry on human samples (fig s2). J Cell Biol (2016) ncbi
mouse monoclonal (SC-35)
  • immunohistochemistry; human; loading ...; fig 6a
MilliporeSigma Srsf2 antibody (Sigma Aldrich, S4045) was used in immunohistochemistry on human samples (fig 6a). Epigenetics Chromatin (2015) ncbi
mouse monoclonal (SC-35)
  • immunocytochemistry; human; 1:500; fig 3
MilliporeSigma Srsf2 antibody (Sigma, 4045) was used in immunocytochemistry on human samples at 1:500 (fig 3). Front Microbiol (2015) ncbi
mouse monoclonal (SC-35)
  • immunocytochemistry; human; 1:200; fig s3
MilliporeSigma Srsf2 antibody (Sigma, S4045) was used in immunocytochemistry on human samples at 1:200 (fig s3). Sci Rep (2015) ncbi
mouse monoclonal (SC-35)
  • immunocytochemistry; human; fig 7a
MilliporeSigma Srsf2 antibody (Sigma-Aldrich, s4045) was used in immunocytochemistry on human samples (fig 7a). Oncogenesis (2015) ncbi
mouse monoclonal (SC-35)
  • immunocytochemistry; human; fig 1b
In order to investigate the function of the alanine repeat-containing C-terminal domain of RNA-binding motif protein 4, MilliporeSigma Srsf2 antibody (Sigma, S4045) was used in immunocytochemistry on human samples (fig 1b). Nucleic Acids Res (2014) ncbi
mouse monoclonal (SC-35)
  • immunocytochemistry; human
MilliporeSigma Srsf2 antibody (Sigma, 4045) was used in immunocytochemistry on human samples . PLoS ONE (2014) ncbi
mouse monoclonal (SC-35)
  • immunocytochemistry; human; 1:2000
In order to study the localization of AID and it's associated proteins, MilliporeSigma Srsf2 antibody (Sigma, S4045) was used in immunocytochemistry on human samples at 1:2000. Exp Cell Res (2014) ncbi
mouse monoclonal (SC-35)
  • immunocytochemistry; human; fig s1
In order to study the role of loss of spliceosome integrity in the development of amyotrophic lateral sclerosis and spinal muscular atrophy, MilliporeSigma Srsf2 antibody (Sigma, SC-35) was used in immunocytochemistry on human samples (fig s1). EMBO Mol Med (2013) ncbi
Articles Reviewed
  1. Yasuda S, Tsuchiya H, Kaiho A, Guo Q, Ikeuchi K, Endo A, et al. Stress- and ubiquitylation-dependent phase separation of the proteasome. Nature. 2020;578:296-300 pubmed publisher
  2. Sajini A, Choudhury N, Wagner R, Bornelöv S, Selmi T, Spanos C, et al. Loss of 5-methylcytosine alters the biogenesis of vault-derived small RNAs to coordinate epidermal differentiation. Nat Commun. 2019;10:2550 pubmed publisher
  3. Tanaka H, Kondo K, Chen X, Homma H, Tagawa K, Kerever A, et al. The intellectual disability gene PQBP1 rescues Alzheimer's disease pathology. Mol Psychiatry. 2018;23:2090-2110 pubmed publisher
  4. Rai A, Chen J, Selbach M, Pelkmans L. Kinase-controlled phase transition of membraneless organelles in mitosis. Nature. 2018;559:211-216 pubmed publisher
  5. Lino Cardenas C, Kessinger C, Cheng Y, MacDonald C, Macgillivray T, Ghoshhajra B, et al. An HDAC9-MALAT1-BRG1 complex mediates smooth muscle dysfunction in thoracic aortic aneurysm. Nat Commun. 2018;9:1009 pubmed publisher
  6. Nozawa R, Boteva L, Soares D, Naughton C, Dun A, Buckle A, et al. SAF-A Regulates Interphase Chromosome Structure through Oligomerization with Chromatin-Associated RNAs. Cell. 2017;169:1214-1227.e18 pubmed publisher
  7. Kobayashi M, Chandrasekhar A, Cheng C, Martinez J, Ng H, de La Hoz C, et al. Diabetic polyneuropathy, sensory neurons, nuclear structure and spliceosome alterations: a role for CWC22. Dis Model Mech. 2017;10:215-224 pubmed publisher
  8. Kuga T, Kume H, Adachi J, Kawasaki N, Shimizu M, Hoshino I, et al. Casein kinase 1 is recruited to nuclear speckles by FAM83H and SON. Sci Rep. 2016;6:34472 pubmed publisher
  9. Skrdlant L, Stark J, Lin R. Myelodysplasia-associated mutations in serine/arginine-rich splicing factor SRSF2 lead to alternative splicing of CDC25C. BMC Mol Biol. 2016;17:18 pubmed publisher
  10. Marzahn M, Marada S, Lee J, Nourse A, Kenrick S, Zhao H, et al. Higher-order oligomerization promotes localization of SPOP to liquid nuclear speckles. EMBO J. 2016;35:1254-75 pubmed publisher
  11. Cammas A, Lacroix Triki M, Pierredon S, Le Bras M, Iacovoni J, Teulade Fichou M, et al. hnRNP A1-mediated translational regulation of the G quadruplex-containing RON receptor tyrosine kinase mRNA linked to tumor progression. Oncotarget. 2016;7:16793-805 pubmed publisher
  12. Even Y, Escande M, Fayet C, Geneviere A. CDK13, a Kinase Involved in Pre-mRNA Splicing, Is a Component of the Perinucleolar Compartment. PLoS ONE. 2016;11:e0149184 pubmed publisher
  13. Ohsaki Y, Kawai T, Yoshikawa Y, Cheng J, Jokitalo E, Fujimoto T. PML isoform II plays a critical role in nuclear lipid droplet formation. J Cell Biol. 2016;212:29-38 pubmed publisher
  14. McCuaig R, Dunn J, Li J, Masch A, Knaute T, Schutkowski M, et al. PKC-Theta is a Novel SC35 Splicing Factor Regulator in Response to T Cell Activation. Front Immunol. 2015;6:562 pubmed publisher
  15. Hübner B, Lomiento M, Mammoli F, Illner D, Markaki Y, Ferrari S, et al. Remodeling of nuclear landscapes during human myelopoietic cell differentiation maintains co-aligned active and inactive nuclear compartments. Epigenetics Chromatin. 2015;8:47 pubmed publisher
  16. Walker E, Jensen L, Croft S, Ghildyal R. Variation in the nuclear effects of infection by different human rhinovirus serotypes. Front Microbiol. 2015;6:875 pubmed publisher
  17. Stockley J, Markert E, Zhou Y, Robson C, Elliott D, Lindberg J, et al. The RNA-binding protein Sam68 regulates expression and transcription function of the androgen receptor splice variant AR-V7. Sci Rep. 2015;5:13426 pubmed publisher
  18. Miller N, Schick K, Timchenko N, Harrison E, Roesler W. The Glutamine-Alanine Repeat Domain of TCERG1 is Required for the Inhibition of the Growth Arrest Activity of C/EBPα. J Cell Biochem. 2016;117:612-20 pubmed publisher
  19. Lefèvre L, Omeiri H, Drougat L, Hantel C, Giraud M, Val P, et al. Combined transcriptome studies identify AFF3 as a mediator of the oncogenic effects of β-catenin in adrenocortical carcinoma. Oncogenesis. 2015;4:e161 pubmed publisher
  20. Cooper Knock J, Higginbottom A, Stopford M, Highley J, Ince P, Wharton S, et al. Antisense RNA foci in the motor neurons of C9ORF72-ALS patients are associated with TDP-43 proteinopathy. Acta Neuropathol. 2015;130:63-75 pubmed publisher
  21. Shishova K, Lavrentyeva E, Dobrucki J, Zatsepina O. Nucleolus-like bodies of fully-grown mouse oocytes contain key nucleolar proteins but are impoverished for rRNA. Dev Biol. 2015;397:267-81 pubmed publisher
  22. Chang S, Chang W, Lu C, Tarn W. Alanine repeats influence protein localization in splicing speckles and paraspeckles. Nucleic Acids Res. 2014;42:13788-98 pubmed publisher
  23. Khalouei S, Chow A, Brown I. Localization of heat shock protein HSPA6 (HSP70B') to sites of transcription in cultured differentiated human neuronal cells following thermal stress. J Neurochem. 2014;131:743-54 pubmed publisher
  24. Witek M, Snook A, Lin J, Blomain E, Xiang B, Magee M, et al. A novel CDX2 isoform regulates alternative splicing. PLoS ONE. 2014;9:e104293 pubmed publisher
  25. Ammon T, Mishra S, Kowalska K, Popowicz G, Holak T, Jentsch S. The conserved ubiquitin-like protein Hub1 plays a critical role in splicing in human cells. J Mol Cell Biol. 2014;6:312-23 pubmed publisher
  26. Cooper Knock J, Walsh M, Higginbottom A, Robin Highley J, Dickman M, Edbauer D, et al. Sequestration of multiple RNA recognition motif-containing proteins by C9orf72 repeat expansions. Brain. 2014;137:2040-51 pubmed publisher
  27. Hett A, West S. Inhibition of U4 snRNA in human cells causes the stable retention of polyadenylated pre-mRNA in the nucleus. PLoS ONE. 2014;9:e96174 pubmed publisher
  28. Hu Y, Ericsson I, Doseth B, Liabakk N, Krokan H, Kavli B. Activation-induced cytidine deaminase (AID) is localized to subnuclear domains enriched in splicing factors. Exp Cell Res. 2014;322:178-92 pubmed publisher
  29. Morchikh M, Naughtin M, Di Nunzio F, Xavier J, Charneau P, Jacob Y, et al. TOX4 and NOVA1 proteins are partners of the LEDGF PWWP domain and affect HIV-1 replication. PLoS ONE. 2013;8:e81217 pubmed publisher
  30. Karunakaran D, Banday A, Wu Q, Kanadia R. Expression analysis of an evolutionarily conserved alternative splicing factor, Sfrs10, in age-related macular degeneration. PLoS ONE. 2013;8:e75964 pubmed publisher
  31. Copeland A, Altamura L, Van Deusen N, Schmaljohn C. Nuclear relocalization of polyadenylate binding protein during rift valley fever virus infection involves expression of the NSs gene. J Virol. 2013;87:11659-69 pubmed publisher
  32. Wolf A, Mantri M, Heim A, Müller U, Fichter E, Mackeen M, et al. The polyserine domain of the lysyl-5 hydroxylase Jmjd6 mediates subnuclear localization. Biochem J. 2013;453:357-70 pubmed publisher
  33. Gavrilov A, Gushchanskaya E, Strelkova O, Zhironkina O, Kireev I, Iarovaia O, et al. Disclosure of a structural milieu for the proximity ligation reveals the elusive nature of an active chromatin hub. Nucleic Acids Res. 2013;41:3563-75 pubmed publisher
  34. Das S, Cong R, Shandilya J, Senapati P, Moindrot B, Monier K, et al. Characterization of nucleolin K88 acetylation defines a new pool of nucleolin colocalizing with pre-mRNA splicing factors. FEBS Lett. 2013;587:417-24 pubmed publisher
  35. Gu B, Eick D, Bensaude O. CTD serine-2 plays a critical role in splicing and termination factor recruitment to RNA polymerase II in vivo. Nucleic Acids Res. 2013;41:1591-603 pubmed publisher
  36. Tsuiji H, Iguchi Y, Furuya A, Kataoka A, Hatsuta H, Atsuta N, et al. Spliceosome integrity is defective in the motor neuron diseases ALS and SMA. EMBO Mol Med. 2013;5:221-34 pubmed publisher