This is a Validated Antibody Database (VAD) review about rat Skp1, based on 18 published articles (read how Labome selects the articles), using Skp1 antibody in all methods. It is aimed to help Labome visitors find the most suited Skp1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Skp1 synonym: Skp1a

Santa Cruz Biotechnology
mouse monoclonal (H-6)
  • western blot; human; loading ...; fig 5d
Santa Cruz Biotechnology Skp1 antibody (Santa Cruz, sc-5281) was used in western blot on human samples (fig 5d). J Exp Clin Cancer Res (2022) ncbi
mouse monoclonal (H-6)
  • western blot; human; 1:1000; loading ...; fig 2d
Santa Cruz Biotechnology Skp1 antibody (Santa Cruz, sc-5281) was used in western blot on human samples at 1:1000 (fig 2d). Cell Death Dis (2021) ncbi
mouse monoclonal (H-6)
  • western blot; human; loading ...; fig 3b
Santa Cruz Biotechnology Skp1 antibody (Santa, sc-5281) was used in western blot on human samples (fig 3b). J Pathol (2019) ncbi
mouse monoclonal (H-6)
  • western blot; human; loading ...; fig 8c
Santa Cruz Biotechnology Skp1 antibody (SantaCruz, sc-5281) was used in western blot on human samples (fig 8c). J Virol (2018) ncbi
mouse monoclonal (H-6)
  • western blot; human; loading ...; fig 3b
Santa Cruz Biotechnology Skp1 antibody (Santa Cruz Biotechnology, sc-5281) was used in western blot on human samples (fig 3b). J Cell Biol (2018) ncbi
mouse monoclonal (H-6)
  • western blot; human; fig 1
In order to study the involvement of TIMELESS in the PARP1-mediated DNA damage response, Santa Cruz Biotechnology Skp1 antibody (Santa Cruz, sc-5281) was used in western blot on human samples (fig 1). Cell Rep (2015) ncbi
mouse monoclonal (H-6)
  • western blot; human; fig 5
Santa Cruz Biotechnology Skp1 antibody (santa Cruz, sc-5281) was used in western blot on human samples (fig 5). Oncotarget (2015) ncbi
mouse monoclonal (H-6)
  • western blot; human; loading ...; fig 1f
Santa Cruz Biotechnology Skp1 antibody (Santa Cruz, sc-5281) was used in western blot on human samples (fig 1f). Nucleic Acids Res (2014) ncbi
Abcam
domestic rabbit monoclonal (EPR3304)
  • immunoprecipitation; human; fig 2
Abcam Skp1 antibody (Epitomics, 2538-1) was used in immunoprecipitation on human samples (fig 2). Oncogene (2016) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (D3J4N)
  • western blot; human; 1:1000; fig 5l
Cell Signaling Technology Skp1 antibody (CST, 12248) was used in western blot on human samples at 1:1000 (fig 5l). Nat Commun (2021) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; human; 1:100; fig 4d, s8
  • western blot; human; 1:100; loading ...; fig s5b, s6e
Cell Signaling Technology Skp1 antibody (Cell Signaling, 2156S) was used in immunohistochemistry - paraffin section on human samples at 1:100 (fig 4d, s8) and in western blot on human samples at 1:100 (fig s5b, s6e). Sci Transl Med (2021) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig 2a
In order to identify and characterize an inhibitor of the COP9 signalosome, Cell Signaling Technology Skp1 antibody (Cell Signaling, 2156) was used in western blot on human samples at 1:1000 (fig 2a). Nat Commun (2016) ncbi
domestic rabbit monoclonal (D3J4N)
  • western blot; mouse; loading ...
Cell Signaling Technology Skp1 antibody (Cell signaling, 12248) was used in western blot on mouse samples . elife (2016) ncbi
domestic rabbit monoclonal (D3J4N)
  • western blot; human; fig 5c
Cell Signaling Technology Skp1 antibody (Cell Signaling, 12248) was used in western blot on human samples (fig 5c). PLoS ONE (2015) ncbi
BD Biosciences
mouse monoclonal (52/p19 [Skp1)
  • western blot; human; loading ...; fig 3a
In order to report the proteome of CADA-treated SUP-T1 human CD4+ T lymphocytes, BD Biosciences Skp1 antibody (BD Biosciences, 52) was used in western blot on human samples (fig 3a). Mol Cell Proteomics (2017) ncbi
mouse monoclonal (52/p19 [Skp1)
  • western blot; human
  • western blot; mouse
In order to identify the mechanistic link between Cullin neddylation and Myc ubiquitination/degradation, BD Biosciences Skp1 antibody (BD Transduction Laboratories, 610530) was used in western blot on human samples and in western blot on mouse samples . Nat Commun (2014) ncbi
mouse monoclonal (52/p19 [Skp1)
  • western blot; human; 1:500; fig 1
In order to investigate the regulation of d-serine synthesis, BD Biosciences Skp1 antibody (BD Biosciences, 610530) was used in western blot on human samples at 1:500 (fig 1). J Biol Chem (2014) ncbi
mouse monoclonal (52/p19 [Skp1)
  • western blot; human
In order to study the role of HERC2 in FBXL5 degradation and iron metabolism, BD Biosciences Skp1 antibody (BD Biosciences, 610530) was used in western blot on human samples . J Biol Chem (2014) ncbi
Articles Reviewed
  1. Salaroglio I, Belisario D, Bironzo P, Ananthanarayanan P, Ricci L, Digiovanni S, et al. SKP2 drives the sensitivity to neddylation inhibitors and cisplatin in malignant pleural mesothelioma. J Exp Clin Cancer Res. 2022;41:75 pubmed publisher
  2. Tang X, Li G, Shi L, Su F, Qian M, Liu Z, et al. Combined intermittent fasting and ERK inhibition enhance the anti-tumor effects of chemotherapy via the GSK3β-SIRT7 axis. Nat Commun. 2021;12:5058 pubmed publisher
  3. Ji M, Zhao Z, Li Y, Xu P, Shi J, Li Z, et al. FBXO6-mediated RNASET2 ubiquitination and degradation governs the development of ovarian cancer. Cell Death Dis. 2021;12:317 pubmed publisher
  4. Li Y, Sun Y, Kulke M, Hechler T, Van der Jeught K, Dong T, et al. Targeted immunotherapy for HER2-low breast cancer with 17p loss. Sci Transl Med. 2021;13: pubmed publisher
  5. Paul D, Islam S, Manne R, Dinesh U, Malonia S, Maity B, et al. F-box protein FBXO16 functions as a tumor suppressor by attenuating nuclear β-catenin function. J Pathol. 2019;248:266-279 pubmed publisher
  6. Liu R, Moss B. Vaccinia Virus C9 Ankyrin Repeat/F-Box Protein Is a Newly Identified Antagonist of the Type I Interferon-Induced Antiviral State. J Virol. 2018;92: pubmed publisher
  7. Pleiner T, Bates M, Gorlich D. A toolbox of anti-mouse and anti-rabbit IgG secondary nanobodies. J Cell Biol. 2018;217:1143-1154 pubmed publisher
  8. Van Puyenbroeck V, Claeys E, Schols D, Bell T, Vermeire K. A Proteomic Survey Indicates Sortilin as a Secondary Substrate of the ER Translocation Inhibitor Cyclotriazadisulfonamide (CADA). Mol Cell Proteomics. 2017;16:157-167 pubmed publisher
  9. Schlierf A, Altmann E, Quancard J, Jefferson A, Assenberg R, Renatus M, et al. Targeted inhibition of the COP9 signalosome for treatment of cancer. Nat Commun. 2016;7:13166 pubmed publisher
  10. Yu Z, Chen T, Li X, Yang M, Tang S, Zhu X, et al. Lys29-linkage of ASK1 by Skp1-Cullin 1-Fbxo21 ubiquitin ligase complex is required for antiviral innate response. elife. 2016;5: pubmed publisher
  11. Han X, Zha Z, Yuan H, Feng X, Xia Y, Lei Q, et al. KDM2B/FBXL10 targets c-Fos for ubiquitylation and degradation in response to mitogenic stimulation. Oncogene. 2016;35:4179-90 pubmed publisher
  12. Young L, Marzio A, Pérez Durán P, Reid D, Meredith D, Roberti D, et al. TIMELESS Forms a Complex with PARP1 Distinct from Its Complex with TIPIN and Plays a Role in the DNA Damage Response. Cell Rep. 2015;13:451-459 pubmed publisher
  13. Sjögren B, Swaney S, Neubig R. FBXO44-Mediated Degradation of RGS2 Protein Uniquely Depends on a Cullin 4B/DDB1 Complex. PLoS ONE. 2015;10:e0123581 pubmed publisher
  14. Cruz Bermúdez A, Vallejo C, Vicente Blanco R, Gallardo M, Fernández Moreno M, Quintanilla M, et al. Enhanced tumorigenicity by mitochondrial DNA mild mutations. Oncotarget. 2015;6:13628-43 pubmed
  15. Chen J, Shin J, Zhao R, Phan L, Wang H, Xue Y, et al. CSN6 drives carcinogenesis by positively regulating Myc stability. Nat Commun. 2014;5:5384 pubmed publisher
  16. Dikopoltsev E, Foltyn V, Zehl M, Jensen O, Mori H, Radzishevsky I, et al. FBXO22 protein is required for optimal synthesis of the N-methyl-D-aspartate (NMDA) receptor coagonist D-serine. J Biol Chem. 2014;289:33904-15 pubmed publisher
  17. Chen Z, Liu B, Tang N, Xu Y, Ye X, Li Z, et al. FBXL5-mediated degradation of single-stranded DNA-binding protein hSSB1 controls DNA damage response. Nucleic Acids Res. 2014;42:11560-9 pubmed publisher
  18. Moroishi T, Yamauchi T, Nishiyama M, Nakayama K. HERC2 targets the iron regulator FBXL5 for degradation and modulates iron metabolism. J Biol Chem. 2014;289:16430-41 pubmed publisher