This is a Validated Antibody Database (VAD) review about rat Sirt7, based on 5 published articles (read how Labome selects the articles), using Sirt7 antibody in all methods. It is aimed to help Labome visitors find the most suited Sirt7 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Sirt7 synonym: NAD-dependent protein deacetylase sirtuin-7; NAD-dependent deacetylase sirtuin-7; SIR2-like protein 7; regulatory protein SIR2 homolog 7

Knockout validation
Cell Signaling Technology
rabbit monoclonal (D3K5A)
  • western blot; rat; loading ...; fig 5a
  • immunohistochemistry knockout validation; mouse; 1:300; loading ...; fig 1c
  • western blot knockout validation; mouse; loading ...; fig 1a
Cell Signaling Technology Sirt7 antibody (Cell Signaling, 5360) was used in western blot on rat samples (fig 5a), in immunohistochemistry knockout validation on mouse samples at 1:300 (fig 1c) and in western blot knockout validation on mouse samples (fig 1a). Sci Rep (2018) ncbi
Cell Signaling Technology
rabbit monoclonal (D3K5A)
  • western blot; rat; loading ...; fig 5a
  • immunohistochemistry knockout validation; mouse; 1:300; loading ...; fig 1c
  • western blot knockout validation; mouse; loading ...; fig 1a
Cell Signaling Technology Sirt7 antibody (Cell Signaling, 5360) was used in western blot on rat samples (fig 5a), in immunohistochemistry knockout validation on mouse samples at 1:300 (fig 1c) and in western blot knockout validation on mouse samples (fig 1a). Sci Rep (2018) ncbi
rabbit monoclonal (D3K5A)
  • immunoprecipitation; human; loading ...; fig 2a
  • western blot; human; loading ...; fig 5i
Cell Signaling Technology Sirt7 antibody (Cell Signaling, D3K5A) was used in immunoprecipitation on human samples (fig 2a) and in western blot on human samples (fig 5i). Oncogene (2017) ncbi
rabbit monoclonal (D3K5A)
  • immunocytochemistry; human; loading ...; fig 2b
  • western blot; human; loading ...; fig 1a
Cell Signaling Technology Sirt7 antibody (Cell Signaling, 5360) was used in immunocytochemistry on human samples (fig 2b) and in western blot on human samples (fig 1a). Nucleic Acids Res (2016) ncbi
rabbit monoclonal (D3K5A)
  • western blot; mouse; 1:1000; fig 5
Cell Signaling Technology Sirt7 antibody (Cell Signaling, 5360) was used in western blot on mouse samples at 1:1000 (fig 5). Nat Commun (2015) ncbi
rabbit monoclonal (D3K5A)
  • western blot; human; 1:250
In order to determine if curcumin can diminish/prevent the development of cardiovascular pathologies, Cell Signaling Technology Sirt7 antibody (Cell Signaling Technology, 9787) was used in western blot on human samples at 1:250. Toxicol Lett (2015) ncbi
Articles Reviewed
  1. Miyasato Y, Yoshizawa T, Sato Y, Nakagawa T, Miyasato Y, Kakizoe Y, et al. Sirtuin 7 Deficiency Ameliorates Cisplatin-induced Acute Kidney Injury Through Regulation of the Inflammatory Response. Sci Rep. 2018;8:5927 pubmed publisher
  2. Li Z, Bridges B, Olson J, Weinman S. The interaction between acetylation and serine-574 phosphorylation regulates the apoptotic function of FOXO3. Oncogene. 2017;36:1887-1898 pubmed publisher
  3. Zhang P, Li G, Deng Z, Liu L, Chen L, Tang J, et al. Dicer interacts with SIRT7 and regulates H3K18 deacetylation in response to DNA damaging agents. Nucleic Acids Res. 2016;44:3629-42 pubmed publisher
  4. Xiao X, Shi X, Fan Y, Zhang X, Wu M, Lan P, et al. GITR subverts Foxp3(+) Tregs to boost Th9 immunity through regulation of histone acetylation. Nat Commun. 2015;6:8266 pubmed publisher
  5. Lewinska A, Wnuk M, Grabowska W, Zabek T, Semik E, Sikora E, et al. Curcumin induces oxidation-dependent cell cycle arrest mediated by SIRT7 inhibition of rDNA transcription in human aortic smooth muscle cells. Toxicol Lett. 2015;233:227-38 pubmed publisher