This is a Validated Antibody Database (VAD) review about rat Shank2, based on 15 published articles (read how Labome selects the articles), using Shank2 antibody in all methods. It is aimed to help Labome visitors find the most suited Shank2 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Shank2 synonym: CortBP1; ProSAP1; Spank-3; SH3 and multiple ankyrin repeat domains protein 2; GKAP/SAPAP-interacting protein; SH3/ankyrin domain gene 2; cortactin-binding protein 1; proline-rich synapse-associated protein 1

Synaptic Systems
rabbit polyclonal (/)
  • western blot; mouse; 1:2000; loading ...; fig ev2f
Synaptic Systems Shank2 antibody (Synaptic Systems, 162202) was used in western blot on mouse samples at 1:2000 (fig ev2f). EMBO J (2019) ncbi
rabbit polyclonal (/)
  • immunocytochemistry; mouse; loading ...; fig 14a
Synaptic Systems Shank2 antibody (Synaptic Systems, 162202) was used in immunocytochemistry on mouse samples (fig 14a). elife (2017) ncbi
rabbit polyclonal (/)
  • western blot; rat; fig 3
Synaptic Systems Shank2 antibody (SYSY, 162202) was used in western blot on rat samples (fig 3). Front Cell Neurosci (2015) ncbi
rabbit polyclonal (/)
  • immunohistochemistry; mouse; 1:400; fig 5
Synaptic Systems Shank2 antibody (Synaptic Systems, 162-C202) was used in immunohistochemistry on mouse samples at 1:400 (fig 5). J Neurosci (2015) ncbi
Neuromab
mouse monoclonal (N23B/49)
  • immunocytochemistry; rat; fig 3
In order to characterize and identify PSD-95 depalmitoylating enzymes, Neuromab Shank2 antibody (NeuroMab, 75-089) was used in immunocytochemistry on rat samples (fig 3). J Neurosci (2016) ncbi
mouse monoclonal (N23B/6)
  • western blot; mouse; fig 7
In order to analyze selective partitioning into complexes and supercomplexes during synapse maturation by NMDA receptors, Neuromab Shank2 antibody (NeuroMab, 75-088) was used in western blot on mouse samples (fig 7). Nat Commun (2016) ncbi
mouse monoclonal (N23B/49)
  • immunocytochemistry; mouse; 1:200; fig 1
In order to assess how rabphilin 3A retains NMDA receptors through interaction with GluN2A/PSD-95 complex synapse sites, Neuromab Shank2 antibody (Neuromab, 75-089) was used in immunocytochemistry on mouse samples at 1:200 (fig 1). Nat Commun (2015) ncbi
mouse monoclonal (N23B/6)
  • western blot; rat; 1:50
In order to characterize rat cerebellar, hippocampal and cortical postsynaptic densities, Neuromab Shank2 antibody (Neuromab, 75-088) was used in western blot on rat samples at 1:50. Neuroscience (2015) ncbi
mouse monoclonal (N23B/49)
  • western blot; mouse; fig 1d
Neuromab Shank2 antibody (NeuroMab, N23B49) was used in western blot on mouse samples (fig 1d). J Neurosci (2015) ncbi
mouse monoclonal (N23B/6)
  • immunohistochemistry; mouse
Neuromab Shank2 antibody (Neuromab, 75-088) was used in immunohistochemistry on mouse samples . Hear Res (2015) ncbi
mouse monoclonal (N23B/49)
  • western blot; mouse; fig 3
In order to assess the effect of andrographolide in a mouse model of Alzheimer's disease, Neuromab Shank2 antibody (NeuroMab, N23B/49) was used in western blot on mouse samples (fig 3). Mol Neurodegener (2014) ncbi
mouse monoclonal (N23B/49)
  • immunohistochemistry; mouse; 1:400
In order to study the role of down syndrome cell adhesion molecule during mice retina development, Neuromab Shank2 antibody (NeuroMab, 75-089) was used in immunohistochemistry on mouse samples at 1:400. Mol Vis (2014) ncbi
mouse monoclonal (N23B/49)
  • immunohistochemistry; mouse
Neuromab Shank2 antibody (NeuroMab, N23B/49) was used in immunohistochemistry on mouse samples . Neuroscience (2014) ncbi
mouse monoclonal (N23B/49)
  • immunohistochemistry - frozen section; mouse; 1:400
  • western blot; mouse; 1:1000
Neuromab Shank2 antibody (NeuroMab, N23B/49) was used in immunohistochemistry - frozen section on mouse samples at 1:400 and in western blot on mouse samples at 1:1000. J Neurosci (2013) ncbi
EMD Millipore
mouse monoclonal (N23B/49)
  • western blot; mouse; fig 5a
EMD Millipore Shank2 antibody (Millipore, MABN24) was used in western blot on mouse samples (fig 5a). Sci Rep (2015) ncbi
Articles Reviewed
  1. Fossati G, Pozzi D, Canzi A, Mirabella F, Valentino S, Morini R, et al. Pentraxin 3 regulates synaptic function by inducing AMPA receptor clustering via ECM remodeling and β1-integrin. EMBO J. 2019;38: pubmed publisher
  2. Daniel J, Cooper B, Palvimo J, Zhang F, Brose N, Tirard M. Analysis of SUMO1-conjugation at synapses. elife. 2017;6: pubmed publisher
  3. Yokoi N, Fukata Y, Sekiya A, Murakami T, Kobayashi K, Fukata M. Identification of PSD-95 Depalmitoylating Enzymes. J Neurosci. 2016;36:6431-44 pubmed publisher
  4. Frank R, Komiyama N, Ryan T, Zhu F, O Dell T, Grant S. NMDA receptors are selectively partitioned into complexes and supercomplexes during synapse maturation. Nat Commun. 2016;7:11264 pubmed publisher
  5. Stanic J, Carta M, Eberini I, Pelucchi S, Marcello E, Genazzani A, et al. Rabphilin 3A retains NMDA receptors at synaptic sites through interaction with GluN2A/PSD-95 complex. Nat Commun. 2015;6:10181 pubmed publisher
  6. Garcia Manteiga J, Bonfiglio S, Folladori L, Malosio M, Lazarevic D, Stupka E, et al. REST-Governed Gene Expression Profiling in a Neuronal Cell Model Reveals Novel Direct and Indirect Processes of Repression and Up-Regulation. Front Cell Neurosci. 2015;9:438 pubmed publisher
  7. Hatanaka Y, Watase K, Wada K, Nagai Y. Abnormalities in synaptic dynamics during development in a mouse model of spinocerebellar ataxia type 1. Sci Rep. 2015;5:16102 pubmed publisher
  8. Farley M, Swulius M, Waxham M. Electron tomographic structure and protein composition of isolated rat cerebellar, hippocampal and cortical postsynaptic densities. Neuroscience. 2015;304:286-301 pubmed publisher
  9. Zhang N, Zhong P, Shin S, Metallo J, Danielson E, Olsen C, et al. S-SCAM, a rare copy number variation gene, induces schizophrenia-related endophenotypes in transgenic mouse model. J Neurosci. 2015;35:1892-904 pubmed publisher
  10. Braude J, Vijayakumar S, Baumgarner K, Laurine R, Jones T, Jones S, et al. Deletion of Shank1 has minimal effects on the molecular composition and function of glutamatergic afferent postsynapses in the mouse inner ear. Hear Res. 2015;321:52-64 pubmed publisher
  11. Williams M, DeSpenza T, Li M, Gulledge A, Luikart B. Hyperactivity of newborn Pten knock-out neurons results from increased excitatory synaptic drive. J Neurosci. 2015;35:943-59 pubmed publisher
  12. Serrano F, Tapia Rojas C, Carvajal F, Hancke J, Cerpa W, Inestrosa N. Andrographolide reduces cognitive impairment in young and mature AβPPswe/PS-1 mice. Mol Neurodegener. 2014;9:61 pubmed publisher
  13. de Andrade G, Kunzelman L, Merrill M, Fuerst P. Developmentally dynamic colocalization patterns of DSCAM with adhesion and synaptic proteins in the mouse retina. Mol Vis. 2014;20:1422-33 pubmed
  14. Tao Cheng J, Thein S, Yang Y, Reese T, Gallant P. Homer is concentrated at the postsynaptic density and does not redistribute after acute synaptic stimulation. Neuroscience. 2014;266:80-90 pubmed publisher
  15. Hoy J, Haeger P, Constable J, Arias R, McCallum R, Kyweriga M, et al. Neuroligin1 drives synaptic and behavioral maturation through intracellular interactions. J Neurosci. 2013;33:9364-84 pubmed publisher