This is a Validated Antibody Database (VAD) review about rat Serpine1, based on 13 published articles (read how Labome selects the articles), using Serpine1 antibody in all methods. It is aimed to help Labome visitors find the most suited Serpine1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Serpine1 synonym: PAI1A; Pai1; Pai1aa; Planh; RATPAI1A; plasminogen activator inhibitor 1; PAI; PAI-1; endothelial plasminogen activator inhibitor; serine (or cysteine) peptidase inhibitor, clade E, member 1; serine (or cysteine) proteinase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1; serine (or cysteine) proteinase inhibitor, clade E, member 1; serine (or cysteine) proteinase inhibitor, member 1; serpin E1; serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1

Abcam
rabbit polyclonal
  • western blot; pig; fig 5
Abcam Serpine1 antibody (Abcam, ab66705) was used in western blot on pig samples (fig 5). J Am Heart Assoc (2016) ncbi
rabbit polyclonal
  • western blot; human; fig 1
Abcam Serpine1 antibody (Abcam, ab66705) was used in western blot on human samples (fig 1). Sci Rep (2015) ncbi
rabbit polyclonal
  • immunohistochemistry; human; 1:1000
Abcam Serpine1 antibody (Abcam, ab66705) was used in immunohistochemistry on human samples at 1:1000. FEBS Lett (2015) ncbi
rabbit polyclonal
  • western blot; human; 1:1000
Abcam Serpine1 antibody (Abcam, ab66705) was used in western blot on human samples at 1:1000. J Mol Endocrinol (2014) ncbi
BD Biosciences
mouse monoclonal (41/PAI-1)
  • other; human; loading ...; fig 4c
BD Biosciences Serpine1 antibody (BD Biosciences, 612024) was used in other on human samples (fig 4c). Cancer Cell (2018) ncbi
mouse monoclonal (41/PAI-1)
  • reverse phase protein lysate microarray; human; loading ...; fig st6
In order to characterize the molecular identity of uterine carcinosarcomas., BD Biosciences Serpine1 antibody (BD Biosciences, 612024) was used in reverse phase protein lysate microarray on human samples (fig st6). Cancer Cell (2017) ncbi
mouse monoclonal (41/PAI-1)
  • reverse phase protein lysate microarray; human; loading ...; fig 3a
In order to describe the features of 228 primary cervical cancers, BD Biosciences Serpine1 antibody (BD Biosciences, 612024) was used in reverse phase protein lysate microarray on human samples (fig 3a). Nature (2017) ncbi
mouse monoclonal (41/PAI-1)
  • western blot; human; loading ...; fig 7e
In order to propose that DLX1 modulates FOXM1 signaling to promote cancer aggressiveness via TGF-beta/SMAD4 signaling in high-grade serous ovarian cancer cells, BD Biosciences Serpine1 antibody (BD Transduction Laboratories, 612024) was used in western blot on human samples (fig 7e). Oncogene (2017) ncbi
mouse monoclonal (41/PAI-1)
  • western blot; human; loading ...; fig 6b
In order to study how CUB domain-containing protein1 contributes to metastasis and drug resistance, BD Biosciences Serpine1 antibody (BD Transduction Laboratories, 612024) was used in western blot on human samples (fig 6b). Breast Cancer Res (2016) ncbi
mouse monoclonal (41/PAI-1)
  • immunohistochemistry - paraffin section; human; 1:200; fig s1
In order to utilize ovarian cancer xenograft models to study dynamic modulation of phosphoprotein expression, BD Biosciences Serpine1 antibody (BD sciences, P612024) was used in immunohistochemistry - paraffin section on human samples at 1:200 (fig s1). BMC Cancer (2016) ncbi
mouse monoclonal (41/PAI-1)
  • western blot; human; 1:5000
In order to show that tamoxifen prevents myofibroblast differentiation, BD Biosciences Serpine1 antibody (BD Biosciences, 612025) was used in western blot on human samples at 1:5000. J Cell Physiol (2015) ncbi
mouse monoclonal (41/PAI-1)
  • western blot; human; fig 11
BD Biosciences Serpine1 antibody (BD Transduction, 612025) was used in western blot on human samples (fig 11). Nucleic Acids Res (2015) ncbi
EMD Millipore
mouse monoclonal
  • other; human; loading ...; fig s1
In order to investigate the mechanisms of toxicity by the negative allosteric modulators of metabotropic glutamate receptor 5, EMD Millipore Serpine1 antibody (Calbiochem, IM29L-100UG) was used in other on human samples (fig s1). Cell Chem Biol (2017) ncbi
Articles Reviewed
  1. Ng P, Li J, Jeong K, Shao S, Chen H, Tsang Y, et al. Systematic Functional Annotation of Somatic Mutations in Cancer. Cancer Cell. 2018;33:450-462.e10 pubmed publisher
  2. Shah F, Stepan A, O Mahony A, Velichko S, Folias A, Houle C, et al. Mechanisms of Skin Toxicity Associated with Metabotropic Glutamate Receptor 5 Negative Allosteric Modulators. Cell Chem Biol. 2017;24:858-869.e5 pubmed publisher
  3. Cherniack A, Shen H, Walter V, Stewart C, Murray B, Bowlby R, et al. Integrated Molecular Characterization of Uterine Carcinosarcoma. Cancer Cell. 2017;31:411-423 pubmed publisher
  4. . Integrated genomic and molecular characterization of cervical cancer. Nature. 2017;543:378-384 pubmed publisher
  5. Chan D, Hui W, Wang J, Yung M, Hui L, Qin Y, et al. DLX1 acts as a crucial target of FOXM1 to promote ovarian cancer aggressiveness by enhancing TGF-β/SMAD4 signaling. Oncogene. 2017;36:1404-1416 pubmed publisher
  6. LAW M, Ferreira R, Davis B, Higgins P, Kim J, Castellano R, et al. CUB domain-containing protein 1 and the epidermal growth factor receptor cooperate to induce cell detachment. Breast Cancer Res. 2016;18:80 pubmed publisher
  7. Eirin A, Ebrahimi B, Kwon S, Fiala J, Williams B, Woollard J, et al. Restoration of Mitochondrial Cardiolipin Attenuates Cardiac Damage in Swine Renovascular Hypertension. J Am Heart Assoc. 2016;5: pubmed publisher
  8. Koussounadis A, Langdon S, Um I, Kay C, Francis K, Harrison D, et al. Dynamic modulation of phosphoprotein expression in ovarian cancer xenograft models. BMC Cancer. 2016;16:205 pubmed publisher
  9. Carthy J, Sundqvist A, Heldin A, van Dam H, Kletsas D, Heldin C, et al. Tamoxifen Inhibits TGF-β-Mediated Activation of Myofibroblasts by Blocking Non-Smad Signaling Through ERK1/2. J Cell Physiol. 2015;230:3084-92 pubmed publisher
  10. Rojas Fernandez A, Herhaus L, MacArtney T, Lachaud C, Hay R, Sapkota G. Rapid generation of endogenously driven transcriptional reporters in cells through CRISPR/Cas9. Sci Rep. 2015;5:9811 pubmed publisher
  11. Liu X, Chen Z, Xu C, Leng X, Cao H, Ouyang G, et al. Repression of hypoxia-inducible factor α signaling by Set7-mediated methylation. Nucleic Acids Res. 2015;43:5081-98 pubmed publisher
  12. Li C, Zhu H, Bai W, Su L, Liu J, Cai W, et al. MiR-10a and miR-181c regulate collagen type I generation in hypertrophic scars by targeting PAI-1 and uPA. FEBS Lett. 2015;589:380-9 pubmed publisher
  13. Tian L, Zhang L, Liu J, Guo T, Gao C, Ni J. Effects of TSH on the function of human umbilical vein endothelial cells. J Mol Endocrinol. 2014;52:215-22 pubmed publisher