This is a Validated Antibody Database (VAD) review about rat SK3, based on 6 published articles (read how Labome selects the articles), using SK3 antibody in all methods. It is aimed to help Labome visitors find the most suited SK3 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
SK3 synonym: KCa2.3; SK3; small conductance calcium-activated potassium channel protein 3; SKCa 3; SKCa3; potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 3; potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3; small-conductance Ca2+-activated K+ channel 3

Alomone Labs
rabbit polyclonal
  • immunohistochemistry - frozen section; rat; 1:1000; loading ...; fig 4e
  • immunocytochemistry; rat; 1:1000; loading ...; fig 1
Alomone Labs SK3 antibody (Alomone, APC-025) was used in immunohistochemistry - frozen section on rat samples at 1:1000 (fig 4e) and in immunocytochemistry on rat samples at 1:1000 (fig 1). J Neurosci Methods (2018) ncbi
rabbit polyclonal
  • immunoprecipitation; rat; fig 2e
  • western blot; rat; 1:1000; fig 2e
Alomone Labs SK3 antibody (Alomone Labs, APC-025) was used in immunoprecipitation on rat samples (fig 2e) and in western blot on rat samples at 1:1000 (fig 2e). J Cell Biochem (2018) ncbi
rabbit polyclonal
  • western blot; rat; loading ...; fig 3a
In order to ask if SK channels in the mitochondria inner membrane play an important role in regulating mitochondrial function in chronic cardiac diseases, Alomone Labs SK3 antibody (Alomone, APC-025) was used in western blot on rat samples (fig 3a). Cardiovasc Res (2017) ncbi
rabbit polyclonal
  • immunohistochemistry - frozen section; mouse; 1:200; fig 5
  • immunocytochemistry; mouse; 1:100; fig 3
  • western blot; mouse; 1:1000; fig 1
In order to utilize the mechanosensitive TRPV4 channel in the collecting duct system of kidney that is coupled to expression of a diverse array of Ca2+-activated K+ channels (SK1/3, IK1, BK), Alomone Labs SK3 antibody (Alomone, APC-025) was used in immunohistochemistry - frozen section on mouse samples at 1:200 (fig 5), in immunocytochemistry on mouse samples at 1:100 (fig 3) and in western blot on mouse samples at 1:1000 (fig 1). PLoS ONE (2016) ncbi
rabbit polyclonal
  • western blot; mouse
Alomone Labs SK3 antibody (Alamone Labs, APC-025) was used in western blot on mouse samples . PLoS ONE (2014) ncbi
MilliporeSigma
rabbit polyclonal
  • western blot; human; 1:250; fig 4
MilliporeSigma SK3 antibody (Sigma-Aldrich, P0608) was used in western blot on human samples at 1:250 (fig 4). Pflugers Arch (2014) ncbi
Articles Reviewed
  1. Jager S, Pallesen L, Vaegter C. Isolation of satellite glial cells for high-quality RNA purification. J Neurosci Methods. 2018;297:1-8 pubmed publisher
  2. Pizzoni A, López González M, Di Giusto G, Rivarola V, Capurro C, Ford P. AQP2 can modulate the pattern of Ca2+ transients induced by store-operated Ca2+ entry under TRPV4 activation. J Cell Biochem. 2018;119:4120-4133 pubmed publisher
  3. Kim T, Terentyeva R, Roder K, Li W, Liu M, Greener I, et al. SK channel enhancers attenuate Ca2+-dependent arrhythmia in hypertrophic hearts by regulating mito-ROS-dependent oxidation and activity of RyR. Cardiovasc Res. 2017;113:343-353 pubmed publisher
  4. Li Y, Hu H, Butterworth M, Tian J, Zhu M, O Neil R. Expression of a Diverse Array of Ca2+-Activated K+ Channels (SK1/3, IK1, BK) that Functionally Couple to the Mechanosensitive TRPV4 Channel in the Collecting Duct System of Kidney. PLoS ONE. 2016;11:e0155006 pubmed publisher
  5. Wandall Frostholm C, Skaarup L, Sadda V, Nielsen G, Hedegaard E, Mogensen S, et al. Pulmonary hypertension in wild type mice and animals with genetic deficit in KCa2.3 and KCa3.1 channels. PLoS ONE. 2014;9:e97687 pubmed publisher
  6. Clarysse L, Gueguinou M, Potier Cartereau M, Vandecasteele G, Bougnoux P, Chevalier S, et al. cAMP-PKA inhibition of SK3 channel reduced both Ca2+ entry and cancer cell migration by regulation of SK3-Orai1 complex. Pflugers Arch. 2014;466:1921-32 pubmed publisher