This is a Validated Antibody Database (VAD) review about rat Rragc, based on 13 published articles (read how Labome selects the articles), using Rragc antibody in all methods. It is aimed to help Labome visitors find the most suited Rragc antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Rragc synonym: ras-related GTP-binding protein C

Knockout validation
Cell Signaling Technology
rabbit polyclonal
  • western blot knockout validation; mouse; 1:1000; fig s1a
Cell Signaling Technology Rragc antibody (Cell signaling, 3360) was used in western blot knockout validation on mouse samples at 1:1000 (fig s1a). Science (2015) ncbi
Cell Signaling Technology
rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig 1s1b
Cell Signaling Technology Rragc antibody (Cell signaling, 3360) was used in western blot on human samples at 1:1000 (fig 1s1b). elife (2019) ncbi
rabbit monoclonal (D31G9)
  • western blot; mouse; loading ...; fig s2g
Cell Signaling Technology Rragc antibody (Cell Signaling, 5466) was used in western blot on mouse samples (fig s2g). Science (2019) ncbi
rabbit monoclonal (D31G9)
  • western blot; human; 1:1000; loading ...; fig 4a
Cell Signaling Technology Rragc antibody (Cell Signaling, 5466) was used in western blot on human samples at 1:1000 (fig 4a). Nat Commun (2018) ncbi
rabbit monoclonal (D8H5)
  • western blot; human; loading ...; fig 2a
Cell Signaling Technology Rragc antibody (Cell Signaling, 9480) was used in western blot on human samples (fig 2a). Nature (2017) ncbi
rabbit polyclonal
  • western blot; human; loading ...; fig 4d
Cell Signaling Technology Rragc antibody (Cell Signaling Technology, 3360) was used in western blot on human samples (fig 4d). Nature (2017) ncbi
rabbit monoclonal (D8H5)
  • immunocytochemistry; human; loading ...; fig 3e
In order to research the role of polo like kinase 1 in MTOR complex 1 and autophagy, Cell Signaling Technology Rragc antibody (Cell Signaling, 9480) was used in immunocytochemistry on human samples (fig 3e). Autophagy (2017) ncbi
rabbit monoclonal (D31G9)
  • western blot; human; loading ...; fig 2a
In order to find and characterize a polypeptide encoded by the long non-coding RNA, LINC00961, Cell Signaling Technology Rragc antibody (Cell Signaling, 5466) was used in western blot on human samples (fig 2a). Nature (2017) ncbi
rabbit monoclonal (D8H5)
  • western blot; human; fig 6a
Cell Signaling Technology Rragc antibody (Cell Signaling, 9480) was used in western blot on human samples (fig 6a). Cell (2016) ncbi
rabbit monoclonal (D31G9)
  • western blot; human; 1:1000; fig s2
In order to elucidate the mechanisms by which mutant IDH1/2 contributes to oncogenesis, Cell Signaling Technology Rragc antibody (Cell signaling, D31G9) was used in western blot on human samples at 1:1000 (fig s2). Nat Commun (2016) ncbi
rabbit polyclonal
  • western blot knockout validation; mouse; 1:1000; fig s1a
Cell Signaling Technology Rragc antibody (Cell signaling, 3360) was used in western blot knockout validation on mouse samples at 1:1000 (fig s1a). Science (2015) ncbi
rabbit monoclonal (D31G9)
  • western blot; human; fig 1
Cell Signaling Technology Rragc antibody (Cell signaling, 5466) was used in western blot on human samples (fig 1). Nature (2015) ncbi
rabbit monoclonal (D8H5)
  • western blot; human; fig 3
Cell Signaling Technology Rragc antibody (Cell Signaling, 9480) was used in western blot on human samples (fig 3). Cell (2014) ncbi
rabbit polyclonal
  • immunocytochemistry; human
  • western blot; human
Cell Signaling Technology Rragc antibody (Cell Signaling Technology, 3360) was used in immunocytochemistry on human samples and in western blot on human samples . J Biol Chem (2014) ncbi
Articles Reviewed
  1. Jewell J, Fu V, Hong A, Yu F, Meng D, Melick C, et al. GPCR signaling inhibits mTORC1 via PKA phosphorylation of Raptor. elife. 2019;8: pubmed publisher
  2. He M, Chaurushiya M, Webster J, Kummerfeld S, Reja R, Chaudhuri S, et al. Intrinsic apoptosis shapes the tumor spectrum linked to inactivation of the deubiquitinase BAP1. Science. 2019;364:283-285 pubmed publisher
  3. Hsu C, Lee E, Gordon K, Paz E, Shen W, Ohnishi K, et al. MAP4K3 mediates amino acid-dependent regulation of autophagy via phosphorylation of TFEB. Nat Commun. 2018;9:942 pubmed publisher
  4. Peng M, Yin N, Li M. SZT2 dictates GATOR control of mTORC1 signalling. Nature. 2017;543:433-437 pubmed publisher
  5. Wolfson R, Chantranupong L, Wyant G, Gu X, Orozco J, Shen K, et al. KICSTOR recruits GATOR1 to the lysosome and is necessary for nutrients to regulate mTORC1. Nature. 2017;543:438-442 pubmed publisher
  6. Ruf S, Heberle A, Langelaar Makkinje M, Gelino S, Wilkinson D, Gerbeth C, et al. PLK1 (polo like kinase 1) inhibits MTOR complex 1 and promotes autophagy. Autophagy. 2017;13:486-505 pubmed publisher
  7. Matsumoto A, Pasut A, Matsumoto M, Yamashita R, Fung J, Monteleone E, et al. mTORC1 and muscle regeneration are regulated by the LINC00961-encoded SPAR polypeptide. Nature. 2017;541:228-232 pubmed publisher
  8. Wu L, Zhou B, Oshiro Rapley N, Li M, Paulo J, Webster C, et al. An Ancient, Unified Mechanism for Metformin Growth Inhibition in C. elegans and Cancer. Cell. 2016;167:1705-1718.e13 pubmed publisher
  9. Carbonneau M, M Gagné L, Lalonde M, Germain M, Motorina A, Guiot M, et al. The oncometabolite 2-hydroxyglutarate activates the mTOR signalling pathway. Nat Commun. 2016;7:12700 pubmed publisher
  10. Jewell J, Kim Y, Russell R, Yu F, Park H, Plouffe S, et al. Metabolism. Differential regulation of mTORC1 by leucine and glutamine. Science. 2015;347:194-8 pubmed publisher
  11. Rebsamen M, Pochini L, Stasyk T, de Araújo M, Galluccio M, Kandasamy R, et al. SLC38A9 is a component of the lysosomal amino acid sensing machinery that controls mTORC1. Nature. 2015;519:477-81 pubmed publisher
  12. Peng M, Yin N, Li M. Sestrins function as guanine nucleotide dissociation inhibitors for Rag GTPases to control mTORC1 signaling. Cell. 2014;159:122-133 pubmed publisher
  13. Oshiro N, Rapley J, Avruch J. Amino acids activate mammalian target of rapamycin (mTOR) complex 1 without changing Rag GTPase guanyl nucleotide charging. J Biol Chem. 2014;289:2658-74 pubmed publisher