This is a Validated Antibody Database (VAD) review about rat Rictor, based on 40 published articles (read how Labome selects the articles), using Rictor antibody in all methods. It is aimed to help Labome visitors find the most suited Rictor antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Knockout validation
Cell Signaling Technology
domestic rabbit monoclonal (53A2)
  • western blot knockout validation; mouse; 1:1000; loading ...; fig 1s1b
Cell Signaling Technology Rictor antibody (CST, 2114) was used in western blot knockout validation on mouse samples at 1:1000 (fig 1s1b). elife (2020) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (53A2)
  • western blot knockout validation; mouse; 1:1000; loading ...; fig ev1 a
Cell Signaling Technology Rictor antibody (Cell Signaling, cs-2114) was used in western blot knockout validation on mouse samples at 1:1000 (fig ev1 a). EMBO Mol Med (2016) ncbi
Santa Cruz Biotechnology
mouse monoclonal (H-11)
  • western blot; human; 1:2000; loading ...; fig 2b
  • western blot; mouse; 1:2000; loading ...; fig 1e
Santa Cruz Biotechnology Rictor antibody (Santa CRuz, sc-271081) was used in western blot on human samples at 1:2000 (fig 2b) and in western blot on mouse samples at 1:2000 (fig 1e). iScience (2022) ncbi
mouse monoclonal (H-11)
  • western blot; human; loading ...; fig s7
Santa Cruz Biotechnology Rictor antibody (Santa, sc-271081) was used in western blot on human samples (fig s7). Cells (2019) ncbi
mouse monoclonal
  • western blot; mouse; fig s5b
Santa Cruz Biotechnology Rictor antibody (Santa Cruz, H-11) was used in western blot on mouse samples (fig s5b). Immunity (2017) ncbi
mouse monoclonal (H-11)
  • western blot; mouse; fig s5b
Santa Cruz Biotechnology Rictor antibody (Santa Cruz, H-11) was used in western blot on mouse samples (fig s5b). Immunity (2017) ncbi
mouse monoclonal (H-11)
  • western blot; human; fig 2
Santa Cruz Biotechnology Rictor antibody (Santa Cruz, sc-271081) was used in western blot on human samples (fig 2). PLoS ONE (2016) ncbi
mouse monoclonal (H-11)
  • western blot; mouse; fig 8
Santa Cruz Biotechnology Rictor antibody (Santa Cruz Biotechnology, sc-271081) was used in western blot on mouse samples (fig 8). J Biol Chem (2014) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (53A2)
  • western blot; human; loading ...; fig 3d
Cell Signaling Technology Rictor antibody (Cell Signaling, 2114) was used in western blot on human samples (fig 3d). Cell Death Dis (2021) ncbi
domestic rabbit monoclonal (53A2)
  • western blot; human; 1:500; loading ...; fig s1d
  • western blot; mouse; 1:500; loading ...; fig s1d
Cell Signaling Technology Rictor antibody (Cell Signaling, 2114) was used in western blot on human samples at 1:500 (fig s1d) and in western blot on mouse samples at 1:500 (fig s1d). Mol Cancer (2021) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:1000; loading ...
Cell Signaling Technology Rictor antibody (Cell Signaling Technology, 2140) was used in western blot on human samples at 1:1000. Nat Commun (2021) ncbi
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig 6c
Cell Signaling Technology Rictor antibody (Cell Signaling Technology, 2140) was used in western blot on mouse samples (fig 6c). J Cell Mol Med (2020) ncbi
domestic rabbit monoclonal (53A2)
  • western blot; human; loading ...; fig 2b
Cell Signaling Technology Rictor antibody (Cell Signaling, 2114) was used in western blot on human samples (fig 2b). BMC Cancer (2020) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 2c
Cell Signaling Technology Rictor antibody (Cell Signaling Technology, 2140) was used in western blot on human samples (fig 2c). Cell (2020) ncbi
domestic rabbit monoclonal (53A2)
  • western blot knockout validation; mouse; 1:1000; loading ...; fig 1s1b
Cell Signaling Technology Rictor antibody (CST, 2114) was used in western blot knockout validation on mouse samples at 1:1000 (fig 1s1b). elife (2020) ncbi
domestic rabbit monoclonal (53A2)
  • western blot; mouse; loading ...; fig 6a
Cell Signaling Technology Rictor antibody (Cell Signaling Technologies, 2114) was used in western blot on mouse samples (fig 6a). Life Sci (2019) ncbi
domestic rabbit monoclonal (53A2)
  • western blot; human; 1:1000; loading ...; fig 5d
Cell Signaling Technology Rictor antibody (Cell Signaling, 2114) was used in western blot on human samples at 1:1000 (fig 5d). Int J Biol Sci (2019) ncbi
domestic rabbit monoclonal (53A2)
  • western blot; human; loading ...; fig 7b
Cell Signaling Technology Rictor antibody (Cell Signaling Technology, 2114) was used in western blot on human samples (fig 7b). J Clin Invest (2019) ncbi
domestic rabbit polyclonal
  • immunohistochemistry; mouse; 1:200; loading ...; fig 5c
  • western blot; mouse; 1:1000; loading ...; fig 5a
Cell Signaling Technology Rictor antibody (Cell Signaling, 2140) was used in immunohistochemistry on mouse samples at 1:200 (fig 5c) and in western blot on mouse samples at 1:1000 (fig 5a). Nature (2019) ncbi
domestic rabbit monoclonal (53A2)
  • western blot; mouse; 1:1000; loading ...; fig s1b
Cell Signaling Technology Rictor antibody (Cell Signaling, 2114) was used in western blot on mouse samples at 1:1000 (fig s1b). Nat Commun (2018) ncbi
domestic rabbit monoclonal (53A2)
  • western blot; human; 1:1000; loading ...; fig 3b
Cell Signaling Technology Rictor antibody (CST, 2114S) was used in western blot on human samples at 1:1000 (fig 3b). Sci Adv (2018) ncbi
domestic rabbit monoclonal (53A2)
  • other; human; loading ...; fig 4c
Cell Signaling Technology Rictor antibody (Cell Signaling, 2114) was used in other on human samples (fig 4c). Cancer Cell (2018) ncbi
domestic rabbit monoclonal (53A2)
  • immunohistochemistry; mouse; loading ...; fig 7e
In order to demonstrate that WHSC1 drives indolent PTEN-null tumors to become metastatic prostate cancer, Cell Signaling Technology Rictor antibody (Cell Signaling, 2114) was used in immunohistochemistry on mouse samples (fig 7e). J Clin Invest (2017) ncbi
domestic rabbit monoclonal (53A2)
  • western blot; human; loading ...; fig 2b
Cell Signaling Technology Rictor antibody (Cell Signaling, 2114) was used in western blot on human samples (fig 2b). Sci Rep (2017) ncbi
domestic rabbit monoclonal (53A2)
  • reverse phase protein lysate microarray; human; loading ...; fig st6
In order to characterize the molecular identity of uterine carcinosarcomas., Cell Signaling Technology Rictor antibody (CST, 2114) was used in reverse phase protein lysate microarray on human samples (fig st6). Cancer Cell (2017) ncbi
domestic rabbit monoclonal (53A2)
  • reverse phase protein lysate microarray; human; loading ...; fig 3a
In order to describe the features of 228 primary cervical cancers, Cell Signaling Technology Rictor antibody (Cell Signaling, 2114) was used in reverse phase protein lysate microarray on human samples (fig 3a). Nature (2017) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig s3g
In order to elucidate that mTORC1 presents tumor suppressor features in conditions of nutrient restrictions, Cell Signaling Technology Rictor antibody (Cell Signaling, 2140) was used in western blot on human samples at 1:1000 (fig s3g). Nat Commun (2017) ncbi
domestic rabbit monoclonal (53A2)
  • western blot; mouse; 1:1000; loading ...; fig 9e
Cell Signaling Technology Rictor antibody (Cell Signaling, 2114) was used in western blot on mouse samples at 1:1000 (fig 9e). J Neurosci (2017) ncbi
domestic rabbit monoclonal (53A2)
  • western blot; mouse; loading ...; fig 6b
In order to confirm that FBXL5 contributes to regulation of neural stem-progenitor cells proliferation during mammalian brain development, Cell Signaling Technology Rictor antibody (CST, 2114) was used in western blot on mouse samples (fig 6b). Mol Cell Biol (2017) ncbi
domestic rabbit monoclonal (53A2)
  • western blot; mouse; loading ...; fig 2e
  • western blot; rat; loading ...; fig 2f
Cell Signaling Technology Rictor antibody (Cell Signalling, 2114) was used in western blot on mouse samples (fig 2e) and in western blot on rat samples (fig 2f). Hum Mol Genet (2017) ncbi
domestic rabbit monoclonal (53A2)
  • western blot; human; 1:1000; loading ...; fig 6a
Cell Signaling Technology Rictor antibody (Cell Signaling, 2114) was used in western blot on human samples at 1:1000 (fig 6a). Oncotarget (2017) ncbi
domestic rabbit monoclonal (53A2)
  • western blot; human; loading ...; fig 2b
Cell Signaling Technology Rictor antibody (Cell Signaling, 2114) was used in western blot on human samples (fig 2b). Oncotarget (2017) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 3b
Cell Signaling Technology Rictor antibody (Cell Signaling Technology, 2140) was used in western blot on human samples (fig 3b). Cell Signal (2017) ncbi
domestic rabbit monoclonal (53A2)
  • western blot; human; 1:1000; fig 1
In order to elucidate the mechanisms by which mutant IDH1/2 contributes to oncogenesis, Cell Signaling Technology Rictor antibody (Cell signaling, 53A2) was used in western blot on human samples at 1:1000 (fig 1). Nat Commun (2016) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig 2h
In order to test if mammalian target of rapamycin complex 2 contributes to podocyte injury during diabetes, Cell Signaling Technology Rictor antibody (Cell Signaling, 2140) was used in western blot on mouse samples at 1:1000 (fig 2h). Antioxid Redox Signal (2016) ncbi
domestic rabbit monoclonal (53A2)
  • immunoprecipitation; human; loading ...; fig 3b
  • western blot; human; loading ...; fig 3b
In order to research the roles of HSF1 and mTORC1 in proteotoxic stress and cell growth, Cell Signaling Technology Rictor antibody (Cell Signaling, 2114) was used in immunoprecipitation on human samples (fig 3b) and in western blot on human samples (fig 3b). Nat Cell Biol (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:1000; fig 3
Cell Signaling Technology Rictor antibody (Cell Signaling Technologies, 2140) was used in western blot on human samples at 1:1000 (fig 3). Nat Commun (2016) ncbi
domestic rabbit monoclonal (53A2)
  • western blot knockout validation; mouse; 1:1000; loading ...; fig ev1 a
Cell Signaling Technology Rictor antibody (Cell Signaling, cs-2114) was used in western blot knockout validation on mouse samples at 1:1000 (fig ev1 a). EMBO Mol Med (2016) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:1000
Cell Signaling Technology Rictor antibody (Cell Signaling, 2140) was used in western blot on mouse samples at 1:1000. Nat Commun (2016) ncbi
domestic rabbit monoclonal (53A2)
  • western blot; human; fig 6
Cell Signaling Technology Rictor antibody (Cell Signaling, 2114) was used in western blot on human samples (fig 6). PLoS ONE (2015) ncbi
domestic rabbit monoclonal (53A2)
  • immunohistochemistry; human; loading ...; fig 2c
  • western blot; mouse; loading ...; fig 1d
Cell Signaling Technology Rictor antibody (Cell Signaling, 53A2) was used in immunohistochemistry on human samples (fig 2c) and in western blot on mouse samples (fig 1d). EMBO Rep (2015) ncbi
domestic rabbit monoclonal (53A2)
  • western blot; mouse; fig 3h
  • western blot; human; fig 1
Cell Signaling Technology Rictor antibody (Cell Signaling Technology, 2114) was used in western blot on mouse samples (fig 3h) and in western blot on human samples (fig 1). Oncotarget (2014) ncbi
domestic rabbit monoclonal (53A2)
  • western blot; mouse; fig 3
Cell Signaling Technology Rictor antibody (Cell Signaling, 2114) was used in western blot on mouse samples (fig 3). Autophagy (2014) ncbi
Articles Reviewed
  1. Serna R, Ramrakhiani A, Hernández J, Chen C, Nakagawa C, Machida T, et al. c-JUN inhibits mTORC2 and glucose uptake to promote self-renewal and obesity. iScience. 2022;25:104325 pubmed publisher
  2. Chen X, Miao M, Zhou M, Chen J, Li D, Zhang L, et al. Poly-L-arginine promotes asthma angiogenesis through induction of FGFBP1 in airway epithelial cells via activation of the mTORC1-STAT3 pathway. Cell Death Dis. 2021;12:761 pubmed publisher
  3. Yan C, Saleh N, Yang J, Nebhan C, Vilgelm A, Reddy E, et al. Novel induction of CD40 expression by tumor cells with RAS/RAF/PI3K pathway inhibition augments response to checkpoint blockade. Mol Cancer. 2021;20:85 pubmed publisher
  4. Zhang Y, Swanda R, Nie L, Liu X, Wang C, Lee H, et al. mTORC1 couples cyst(e)ine availability with GPX4 protein synthesis and ferroptosis regulation. Nat Commun. 2021;12:1589 pubmed publisher
  5. Zhao L, Fan M, Zhao L, Yun H, Yang Y, Wang C, et al. Fibroblast growth factor 1 ameliorates adipose tissue inflammation and systemic insulin resistance via enhancing adipocyte mTORC2/Rictor signal. J Cell Mol Med. 2020;24:12813-12825 pubmed publisher
  6. Saurabh K, Shah P, Doll M, Siskind L, Beverly L. UBR-box containing protein, UBR5, is over-expressed in human lung adenocarcinoma and is a potential therapeutic target. BMC Cancer. 2020;20:824 pubmed publisher
  7. Koundouros N, Karali E, Tripp A, Valle A, Inglese P, Perry N, et al. Metabolic Fingerprinting Links Oncogenic PIK3CA with Enhanced Arachidonic Acid-Derived Eicosanoids. Cell. 2020;181:1596-1611.e27 pubmed publisher
  8. McCabe M, Cullen E, Barrows C, Shore A, Tooke K, Laprade K, et al. Genetic inactivation of mTORC1 or mTORC2 in neurons reveals distinct functions in glutamatergic synaptic transmission. elife. 2020;9: pubmed publisher
  9. Barbero G, Castro M, Villanueva M, Quezada M, Fernández N, Demorrow S, et al. An Autocrine Wnt5a Loop Promotes NF-κB Pathway Activation and Cytokine/Chemokine Secretion in Melanoma. Cells. 2019;8: pubmed publisher
  10. Gao H, Freeling J, Wu P, Liang A, Wang X, Li Y. UCHL1 regulates muscle fibers and mTORC1 activity in skeletal muscle. Life Sci. 2019;233:116699 pubmed publisher
  11. Wang H, Huang F, Zhang Z, Wang P, Luo Y, Li H, et al. Feedback Activation of SGK3 and AKT Contributes to Rapamycin Resistance by Reactivating mTORC1/4EBP1 Axis via TSC2 in Breast Cancer. Int J Biol Sci. 2019;15:929-941 pubmed publisher
  12. Wang W, Shen T, Dong B, Creighton C, Meng Y, Zhou W, et al. MAPK4 overexpression promotes tumor progression via noncanonical activation of AKT/mTOR signaling. J Clin Invest. 2019;: pubmed publisher
  13. Poulopoulos A, Murphy A, Ozkan A, Davis P, Hatch J, Kirchner R, et al. Subcellular transcriptomes and proteomes of developing axon projections in the cerebral cortex. Nature. 2019;565:356-360 pubmed publisher
  14. Wang F, Meng M, Mo B, Yang Y, Ji Y, Huang P, et al. Crosstalks between mTORC1 and mTORC2 variagate cytokine signaling to control NK maturation and effector function. Nat Commun. 2018;9:4874 pubmed publisher
  15. NGUYEN J, Ray C, Fox A, Mendonça D, Kim J, Krebsbach P. Mammalian EAK-7 activates alternative mTOR signaling to regulate cell proliferation and migration. Sci Adv. 2018;4:eaao5838 pubmed publisher
  16. Ng P, Li J, Jeong K, Shao S, Chen H, Tsang Y, et al. Systematic Functional Annotation of Somatic Mutations in Cancer. Cancer Cell. 2018;33:450-462.e10 pubmed publisher
  17. Kishore M, Cheung K, Fu H, Bonacina F, Wang G, Coe D, et al. Regulatory T Cell Migration Is Dependent on Glucokinase-Mediated Glycolysis. Immunity. 2017;47:875-889.e10 pubmed publisher
  18. Li N, Xue W, Yuan H, Dong B, Ding Y, Liu Y, et al. AKT-mediated stabilization of histone methyltransferase WHSC1 promotes prostate cancer metastasis. J Clin Invest. 2017;127:1284-1302 pubmed publisher
  19. Merhi A, Delree P, Marini A. The metabolic waste ammonium regulates mTORC2 and mTORC1 signaling. Sci Rep. 2017;7:44602 pubmed publisher
  20. Cherniack A, Shen H, Walter V, Stewart C, Murray B, Bowlby R, et al. Integrated Molecular Characterization of Uterine Carcinosarcoma. Cancer Cell. 2017;31:411-423 pubmed publisher
  21. . Integrated genomic and molecular characterization of cervical cancer. Nature. 2017;543:378-384 pubmed publisher
  22. Villar V, Nguyen T, Delcroix V, Terés S, Bouchecareilh M, Salin B, et al. mTORC1 inhibition in cancer cells protects from glutaminolysis-mediated apoptosis during nutrient limitation. Nat Commun. 2017;8:14124 pubmed publisher
  23. Hussain R, Macklin W. Integrin-Linked Kinase (ILK) Deletion Disrupts Oligodendrocyte Development by Altering Cell Cycle. J Neurosci. 2017;37:397-412 pubmed publisher
  24. Yamauchi T, Nishiyama M, Moroishi T, Kawamura A, Nakayama K. FBXL5 Inactivation in Mouse Brain Induces Aberrant Proliferation of Neural Stem Progenitor Cells. Mol Cell Biol. 2017;37: pubmed publisher
  25. Jin F, Jiang K, Ji S, Wang L, Ni Z, Huang F, et al. Deficient TSC1/TSC2-complex suppression of SOX9-osteopontin-AKT signalling cascade constrains tumour growth in tuberous sclerosis complex. Hum Mol Genet. 2017;26:407-419 pubmed publisher
  26. Fourneaux B, Chaire V, Lucchesi C, Karanian M, Pineau R, Laroche Clary A, et al. Dual inhibition of the PI3K/AKT/mTOR pathway suppresses the growth of leiomyosarcomas but leads to ERK activation through mTORC2: biological and clinical implications. Oncotarget. 2017;8:7878-7890 pubmed publisher
  27. Sakre N, Wildey G, Behtaj M, Kresak A, Yang M, Fu P, et al. RICTOR amplification identifies a subgroup in small cell lung cancer and predicts response to drugs targeting mTOR. Oncotarget. 2017;8:5992-6002 pubmed publisher
  28. Hau A, Leivo M, Gilder A, Hu J, Gonias S, Hansel D. mTORC2 activation is regulated by the urokinase receptor (uPAR) in bladder cancer. Cell Signal. 2017;29:96-106 pubmed publisher
  29. Carbonneau M, M Gagné L, Lalonde M, Germain M, Motorina A, Guiot M, et al. The oncometabolite 2-hydroxyglutarate activates the mTOR signalling pathway. Nat Commun. 2016;7:12700 pubmed publisher
  30. Eid S, Boutary S, Braych K, Sabra R, Massaad C, Hamdy A, et al. mTORC2 Signaling Regulates Nox4-Induced Podocyte Depletion in Diabetes. Antioxid Redox Signal. 2016;25:703-719 pubmed
  31. Cui Y, Zhao J, Yi L, Jiang Y. microRNA-153 Targets mTORC2 Component Rictor to Inhibit Glioma Cells. PLoS ONE. 2016;11:e0156915 pubmed publisher
  32. Su K, Cao J, Tang Z, Dai S, He Y, Sampson S, et al. HSF1 critically attunes proteotoxic stress sensing by mTORC1 to combat stress and promote growth. Nat Cell Biol. 2016;18:527-39 pubmed publisher
  33. Gandin V, Masvidal L, Cargnello M, Gyenis L, McLaughlan S, Cai Y, et al. mTORC1 and CK2 coordinate ternary and eIF4F complex assembly. Nat Commun. 2016;7:11127 pubmed publisher
  34. Albert V, Svensson K, Shimobayashi M, Colombi M, Munoz S, Jimenez V, et al. mTORC2 sustains thermogenesis via Akt-induced glucose uptake and glycolysis in brown adipose tissue. EMBO Mol Med. 2016;8:232-46 pubmed publisher
  35. Kim K, Qiang L, Hayden M, Sparling D, Purcell N, Pajvani U. mTORC1-independent Raptor prevents hepatic steatosis by stabilizing PHLPP2. Nat Commun. 2016;7:10255 pubmed publisher
  36. Yasuda K, Takahashi M, Mori N. Mdm20 Modulates Actin Remodeling through the mTORC2 Pathway via Its Effect on Rictor Expression. PLoS ONE. 2015;10:e0142943 pubmed publisher
  37. Zidek L, Ackermann T, Hartleben G, Eichwald S, Kortman G, Kiehntopf M, et al. Deficiency in mTORC1-controlled C/EBPβ-mRNA translation improves metabolic health in mice. EMBO Rep. 2015;16:1022-36 pubmed publisher
  38. Kazyken D, Kaz Y, Kiyan V, Zhylkibayev A, Chen C, Agarwal N, et al. The nuclear import of ribosomal proteins is regulated by mTOR. Oncotarget. 2014;5:9577-93 pubmed
  39. Zhang D, Tong X, Arthurs B, Guha A, Rui L, Kamath A, et al. Liver clock protein BMAL1 promotes de novo lipogenesis through insulin-mTORC2-AKT signaling. J Biol Chem. 2014;289:25925-35 pubmed publisher
  40. Tan S, Shui G, Zhou J, Shi Y, Huang J, Xia D, et al. Critical role of SCD1 in autophagy regulation via lipogenesis and lipid rafts-coupled AKT-FOXO1 signaling pathway. Autophagy. 2014;10:226-42 pubmed publisher