This is a Validated Antibody Database (VAD) review about rat RGD1562690, based on 25 published articles (read how Labome selects the articles), using RGD1562690 antibody in all methods. It is aimed to help Labome visitors find the most suited RGD1562690 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Knockout validation
Cell Signaling Technology
rabbit polyclonal
  • western blot knockout validation; human; loading ...; fig s3a
In order to study the activation of TAK1 by interleukin-1 and TRAF6, Cell Signaling Technology RGD1562690 antibody (Cell Signaling, 2012) was used in western blot knockout validation on human samples (fig s3a). Biochem J (2017) ncbi
Cell Signaling Technology
rabbit polyclonal
  • western blot knockout validation; mouse; loading ...; fig s1b
Cell Signaling Technology RGD1562690 antibody (Cell Signaling, 2012S) was used in western blot knockout validation on mouse samples (fig s1b). Science (2016) ncbi
Abcam
rabbit monoclonal (EP1566Y)
  • immunocytochemistry; rat; 1:100; fig 1f
  • western blot; rat; 1:1000; loading ...; fig 1e
In order to describe a critical role of the ion channel subunit KChIP2 in maintaining electrical stability in cardiac pathology, Abcam RGD1562690 antibody (Abcam, ab52488) was used in immunocytochemistry on rat samples at 1:100 (fig 1f) and in western blot on rat samples at 1:1000 (fig 1e). elife (2017) ncbi
rabbit monoclonal (EP1566Y)
  • western blot; rat; 1:10,000; loading ...; tbl 1
In order to test if white tea improves prediabetes-induced male reproductive dysfunction, Abcam RGD1562690 antibody (Abcam, ab52488) was used in western blot on rat samples at 1:10,000 (tbl 1). J Nutr Biochem (2016) ncbi
Invitrogen
rabbit polyclonal
  • other; human; 1:100; loading ...; fig 4a
In order to determine if cytosolic lactate is metabolized by the mitochondria of fermenting mammalian cells, Invitrogen RGD1562690 antibody (Thermo Scientific, PA5-17183) was used in other on human samples at 1:100 (fig 4a). Nat Chem Biol (2016) ncbi
rabbit polyclonal
  • western blot; human
In order to identify the metabolic phenotype associated with breast cancer stem cells, Invitrogen RGD1562690 antibody (Thermo Scientific, PA5-27406) was used in western blot on human samples . Cell Death Dis (2014) ncbi
Cell Signaling Technology
rabbit polyclonal
  • western blot knockout validation; human; loading ...; fig s3a
In order to study the activation of TAK1 by interleukin-1 and TRAF6, Cell Signaling Technology RGD1562690 antibody (Cell Signaling, 2012) was used in western blot knockout validation on human samples (fig s3a). Biochem J (2017) ncbi
rabbit polyclonal
  • immunohistochemistry; human; 1:200; fig 7a
  • western blot; human; loading ...; fig 2a
In order to report that lactate dehydrogenase A phosphorylation results in pro-invasive, anti-anoikis, and pro-metastatic advantages to cancer cells, Cell Signaling Technology RGD1562690 antibody (Cell Signaling Technology, 8176) was used in immunohistochemistry on human samples at 1:200 (fig 7a) and in western blot on human samples (fig 2a). Oncogene (2017) ncbi
rabbit polyclonal
  • western blot knockout validation; mouse; loading ...; fig s1b
Cell Signaling Technology RGD1562690 antibody (Cell Signaling, 2012S) was used in western blot knockout validation on mouse samples (fig s1b). Science (2016) ncbi
rabbit polyclonal
  • western blot; human; 1:200; fig st1
In order to identify and characterize alterations in signal transduction that occur during the development Lapatinib resistance, Cell Signaling Technology RGD1562690 antibody (Cell Signaling, 2012) was used in western blot on human samples at 1:200 (fig st1). Nat Commun (2016) ncbi
rabbit polyclonal
  • western blot; human; fig 3
In order to study the reprogramming of glucose metabolism in cancer cells by ROS-mediated stabilization of HIF1alpha via the immunoregulatory protein B7-H3, Cell Signaling Technology RGD1562690 antibody (Cell Signaling Technology, 2012) was used in western blot on human samples (fig 3). Cancer Res (2016) ncbi
rabbit polyclonal
  • western blot; human; fig 4
In order to investigate protection of ovarian cancer-associated fibroblasts against oxidative stress by autophagy, Cell Signaling Technology RGD1562690 antibody (Cell Signaling Technology, 2012) was used in western blot on human samples (fig 4). Cell Cycle (2016) ncbi
rabbit monoclonal (C28H7)
  • immunohistochemistry - paraffin section; human; 1:250; fig 2
Cell Signaling Technology RGD1562690 antibody (Cell Signaling, 3558) was used in immunohistochemistry - paraffin section on human samples at 1:250 (fig 2). PLoS ONE (2016) ncbi
rabbit polyclonal
  • western blot; human; fig 3
In order to study the cellular origin of human induced pluripotent stem cells and human embryonic stem cells, Cell Signaling Technology RGD1562690 antibody (Cell Signaling, 2012S) was used in western blot on human samples (fig 3). Nat Biotechnol (2015) ncbi
rabbit polyclonal
  • western blot; human; fig 4
Cell Signaling Technology RGD1562690 antibody (Cell Signaling Technology, 2012) was used in western blot on human samples (fig 4). Mol Cancer Res (2016) ncbi
rabbit polyclonal
  • western blot; human; 1:1000; fig 4g
  • western blot; mouse; 1:1000; fig 6l
Cell Signaling Technology RGD1562690 antibody (Cell Signaling Technology, 2012) was used in western blot on human samples at 1:1000 (fig 4g) and in western blot on mouse samples at 1:1000 (fig 6l). FASEB J (2016) ncbi
rabbit polyclonal
  • western blot; mouse; fig 3
Cell Signaling Technology RGD1562690 antibody (Cell Signaling, 2012) was used in western blot on mouse samples (fig 3). PLoS ONE (2015) ncbi
rabbit polyclonal
  • western blot; human
  • western blot; rat
Cell Signaling Technology RGD1562690 antibody (Cell Signaling, #2012) was used in western blot on human samples and in western blot on rat samples . Mol Cell Biochem (2015) ncbi
rabbit monoclonal (C28H7)
  • western blot; human; fig 1
Cell Signaling Technology RGD1562690 antibody (Cell Signaling, 3558) was used in western blot on human samples (fig 1). Mol Cancer Ther (2015) ncbi
rabbit polyclonal
  • western blot; human
Cell Signaling Technology RGD1562690 antibody (Cell signaling, 2012) was used in western blot on human samples . PLoS ONE (2015) ncbi
rabbit polyclonal
  • western blot; human
Cell Signaling Technology RGD1562690 antibody (Cell signaling, 2012) was used in western blot on human samples . Cancer Cell Int (2015) ncbi
rabbit monoclonal (C28H7)
  • western blot; human; fig 1f
Cell Signaling Technology RGD1562690 antibody (Cell Signaling Technology, 3558) was used in western blot on human samples (fig 1f). Oncogene (2015) ncbi
rabbit polyclonal
  • western blot; human
Cell Signaling Technology RGD1562690 antibody (Cell Signaling, 2012) was used in western blot on human samples . J Proteome Res (2014) ncbi
rabbit polyclonal
  • western blot; human
Cell Signaling Technology RGD1562690 antibody (Cell Signaling, 2012) was used in western blot on human samples . Mol Cancer Ther (2014) ncbi
rabbit polyclonal
  • western blot; rat
Cell Signaling Technology RGD1562690 antibody (CST, 2012S) was used in western blot on rat samples . FASEB J (2014) ncbi
rabbit polyclonal
  • western blot; rat; 1:1000
In order to study HIF-1alpha mediated metabolic switching and mitochondrial remodeling in bladder outlet obstruction, Cell Signaling Technology RGD1562690 antibody (Cell Signaling, 2012) was used in western blot on rat samples at 1:1000. Lab Invest (2014) ncbi
rabbit polyclonal
  • western blot; human
Cell Signaling Technology RGD1562690 antibody (Cell Signaling Technology, 2012) was used in western blot on human samples . Mol Genet Metab (2013) ncbi
Articles Reviewed
  1. Zhang J, MacArtney T, Peggie M, Cohen P. Interleukin-1 and TRAF6-dependent activation of TAK1 in the absence of TAB2 and TAB3. Biochem J. 2017;474:2235-2248 pubmed publisher
  2. Nassal D, Wan X, Liu H, Maleski D, Ramirez Navarro A, Moravec C, et al. KChIP2 is a core transcriptional regulator of cardiac excitability. elife. 2017;6: pubmed publisher
  3. Jin L, Chun J, Pan C, Alesi G, Li D, Magliocca K, et al. Phosphorylation-mediated activation of LDHA promotes cancer cell invasion and tumour metastasis. Oncogene. 2017;36:3797-3806 pubmed publisher
  4. Peng M, Yin N, Chhangawala S, Xu K, Leslie C, Li M. Aerobic glycolysis promotes T helper 1 cell differentiation through an epigenetic mechanism. Science. 2016;354:481-484 pubmed
  5. Treindl F, Ruprecht B, Beiter Y, Schultz S, Döttinger A, Staebler A, et al. A bead-based western for high-throughput cellular signal transduction analyses. Nat Commun. 2016;7:12852 pubmed publisher
  6. Dias T, Alves M, Rato L, Casal S, Silva B, Oliveira P. White tea intake prevents prediabetes-induced metabolic dysfunctions in testis and epididymis preserving sperm quality. J Nutr Biochem. 2016;37:83-93 pubmed publisher
  7. Chen Y, Mahieu N, Huang X, Singh M, Crawford P, Johnson S, et al. Lactate metabolism is associated with mammalian mitochondria. Nat Chem Biol. 2016;12:937-943 pubmed publisher
  8. Lim S, Liu H, Madeira da Silva L, Arora R, Liu Z, Phillips J, et al. Immunoregulatory Protein B7-H3 Reprograms Glucose Metabolism in Cancer Cells by ROS-Mediated Stabilization of HIF1?. Cancer Res. 2016;76:2231-42 pubmed publisher
  9. Wang Q, Xue L, Zhang X, Bu S, Zhu X, Lai D. Autophagy protects ovarian cancer-associated fibroblasts against oxidative stress. Cell Cycle. 2016;15:1376-85 pubmed publisher
  10. Mohammad G, Olde Damink S, Malago M, Dhar D, Pereira S. Pyruvate Kinase M2 and Lactate Dehydrogenase A Are Overexpressed in Pancreatic Cancer and Correlate with Poor Outcome. PLoS ONE. 2016;11:e0151635 pubmed publisher
  11. Choi J, Lee S, Mallard W, Clement K, Tagliazucchi G, Lim H, et al. A comparison of genetically matched cell lines reveals the equivalence of human iPSCs and ESCs. Nat Biotechnol. 2015;33:1173-81 pubmed publisher
  12. Agarwal S, Bell C, Taylor S, Moran R. p53 Deletion or Hotspot Mutations Enhance mTORC1 Activity by Altering Lysosomal Dynamics of TSC2 and Rheb. Mol Cancer Res. 2016;14:66-77 pubmed publisher
  13. Sharma B, Kolhe R, Black S, Keller J, Mivechi N, Satyanarayana A. Inhibitor of differentiation 1 transcription factor promotes metabolic reprogramming in hepatocellular carcinoma cells. FASEB J. 2016;30:262-75 pubmed publisher
  14. Ledee D, Smith L, Bruce M, Kajimoto M, Isern N, Portman M, et al. c-Myc Alters Substrate Utilization and O-GlcNAc Protein Posttranslational Modifications without Altering Cardiac Function during Early Aortic Constriction. PLoS ONE. 2015;10:e0135262 pubmed publisher
  15. Clarke C, Rudland P, Barraclough R. The metastasis-inducing protein AGR2 is O-glycosylated upon secretion from mammary epithelial cells. Mol Cell Biochem. 2015;408:245-52 pubmed publisher
  16. Khatri R, Shah P, Guha R, Rassool F, Tomkinson A, Brodie A, et al. Aromatase Inhibitor-Mediated Downregulation of INrf2 (Keap1) Leads to Increased Nrf2 and Resistance in Breast Cancer. Mol Cancer Ther. 2015;14:1728-37 pubmed publisher
  17. Bogaerts E, Heindryckx F, Devisscher L, Paridaens A, Vandewynckel Y, Van den Bussche A, et al. Time-dependent effect of hypoxia on tumor progression and liver progenitor cell markers in primary liver tumors. PLoS ONE. 2015;10:e0119555 pubmed publisher
  18. Li Y, Cao Y, Wu X, Han G, Wang L, Zhang Y, et al. The association between Salt-inducible kinase 2 (SIK2) and gamma isoform of the regulatory subunit B55 of PP2A (B55gamma) contributes to the survival of glioma cells under glucose depletion through inhibiting the phosphorylation of S6K. Cancer Cell Int. 2015;15:21 pubmed publisher
  19. Ciavardelli D, Rossi C, Barcaroli D, Volpe S, Consalvo A, Zucchelli M, et al. Breast cancer stem cells rely on fermentative glycolysis and are sensitive to 2-deoxyglucose treatment. Cell Death Dis. 2014;5:e1336 pubmed publisher
  20. Liu X, Yao J, Tripathi D, Ding Z, Xu Y, Sun M, et al. Autophagy mediates HIF2? degradation and suppresses renal tumorigenesis. Oncogene. 2015;34:2450-60 pubmed publisher
  21. Cholewa B, Pellitteri Hahn M, Scarlett C, Ahmad N. Large-scale label-free comparative proteomics analysis of polo-like kinase 1 inhibition via the small-molecule inhibitor BI 6727 (Volasertib) in BRAF(V600E) mutant melanoma cells. J Proteome Res. 2014;13:5041-50 pubmed publisher
  22. Unger G, Kren B, Korman V, Kimbrough T, Vogel R, Ondrey F, et al. Mechanism and efficacy of sub-50-nm tenfibgen nanocapsules for cancer cell-directed delivery of anti-CK2 RNAi to primary and metastatic squamous cell carcinoma. Mol Cancer Ther. 2014;13:2018-29 pubmed publisher
  23. Smith I, Godinez G, Singh B, McCaughey K, Alcantara R, Gururaja T, et al. Inhibition of Janus kinase signaling during controlled mechanical ventilation prevents ventilation-induced diaphragm dysfunction. FASEB J. 2014;28:2790-803 pubmed publisher
  24. Ekman M, Uvelius B, Albinsson S, Swärd K. HIF-mediated metabolic switching in bladder outlet obstruction mitigates the relaxing effect of mitochondrial inhibition. Lab Invest. 2014;94:557-68 pubmed publisher
  25. Kitaoka Y, Ogborn D, Mocellin N, Schlattner U, Tarnopolsky M. Monocarboxylate transporters and mitochondrial creatine kinase protein content in McArdle disease. Mol Genet Metab. 2013;108:259-62 pubmed publisher