This is a Validated Antibody Database (VAD) review about rat RGD1359108, based on 3 published articles (read how Labome selects the articles), using RGD1359108 antibody in all methods. It is aimed to help Labome visitors find the most suited RGD1359108 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
RGD1359108 synonym: guanine nucleotide exchange C9orf72 homolog; protein C9orf72 homolog

Proteintech Group
mouse monoclonal (3D2H6)
  • western blot; mouse; 1:3000; loading ...; fig 3a
In order to elucidate the mechanism by which intronic hexanucleotide expansions in C9ORF72 contribute to amyotrophic lateral sclerosis, Proteintech Group RGD1359108 antibody (Proteintech, 66140-1-Ig) was used in western blot on mouse samples at 1:3000 (fig 3a). Nat Neurosci (2016) ncbi
rabbit polyclonal
  • western blot; mouse; fig 2
Proteintech Group RGD1359108 antibody (Proteintech, 22637-1-AP) was used in western blot on mouse samples (fig 2). EMBO J (2016) ncbi
rabbit polyclonal
  • immunocytochemistry; human; 1:500; loading ...; fig 1c
  • western blot; human; 1:1000; loading ...; fig 1a
  • immunocytochemistry; mouse; 1:500; loading ...; fig 1c
  • western blot; mouse; 1:1000; loading ...; fig 1a
Proteintech Group RGD1359108 antibody (Proteintech, 22637-1-AP) was used in immunocytochemistry on human samples at 1:500 (fig 1c), in western blot on human samples at 1:1000 (fig 1a), in immunocytochemistry on mouse samples at 1:500 (fig 1c) and in western blot on mouse samples at 1:1000 (fig 1a). Mol Neurobiol (2017) ncbi
Articles Reviewed
  1. Sivadasan R, Hornburg D, Drepper C, Frank N, Jablonka S, Hansel A, et al. C9ORF72 interaction with cofilin modulates actin dynamics in motor neurons. Nat Neurosci. 2016;19:1610-1618 pubmed publisher
  2. Sellier C, Campanari M, Julie Corbier C, Gaucherot A, Kolb Cheynel I, Oulad Abdelghani M, et al. Loss of C9ORF72 impairs autophagy and synergizes with polyQ Ataxin-2 to induce motor neuron dysfunction and cell death. EMBO J. 2016;35:1276-97 pubmed publisher
  3. Maharjan N, Künzli C, Buthey K, Saxena S. C9ORF72 Regulates Stress Granule Formation and Its Deficiency Impairs Stress Granule Assembly, Hypersensitizing Cells to Stress. Mol Neurobiol. 2017;54:3062-3077 pubmed publisher