This is a Validated Antibody Database (VAD) review about rat Prkdc, based on 13 published articles (read how Labome selects the articles), using Prkdc antibody in all methods. It is aimed to help Labome visitors find the most suited Prkdc antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Knockout validation
Santa Cruz Biotechnology
mouse monoclonal (G-12)
  • western blot knockout validation; human; loading ...; fig 5a
Santa Cruz Biotechnology Prkdc antibody (Santa Cruz, G12) was used in western blot knockout validation on human samples (fig 5a). elife (2020) ncbi
Santa Cruz Biotechnology
mouse monoclonal
  • western blot knockout validation; human; loading ...; fig 5a
Santa Cruz Biotechnology Prkdc antibody (Santa Cruz, G12) was used in western blot knockout validation on human samples (fig 5a). elife (2020) ncbi
Santa Cruz Biotechnology
mouse monoclonal
  • western blot knockout validation; human; loading ...; fig 5a
Santa Cruz Biotechnology Prkdc antibody (Santa Cruz, G12) was used in western blot knockout validation on human samples (fig 5a). elife (2020) ncbi
mouse monoclonal (G-12)
  • western blot knockout validation; human; loading ...; fig 5a
Santa Cruz Biotechnology Prkdc antibody (Santa Cruz, G12) was used in western blot knockout validation on human samples (fig 5a). elife (2020) ncbi
mouse monoclonal (G-12)
  • western blot; human; loading ...; fig 1b
Santa Cruz Biotechnology Prkdc antibody (Santa Cruz, sc-390849) was used in western blot on human samples (fig 1b). elife (2020) ncbi
mouse monoclonal (E-6)
  • immunocytochemistry; human; loading ...; fig 6i
Santa Cruz Biotechnology Prkdc antibody (Santa Cruz, sc390698) was used in immunocytochemistry on human samples (fig 6i). J Cell Physiol (2017) ncbi
mouse monoclonal (E-3)
  • western blot; human; 1:500; loading ...; fig s6b
Santa Cruz Biotechnology Prkdc antibody (Santa Cruz, sc-390495) was used in western blot on human samples at 1:500 (fig s6b). PLoS ONE (2016) ncbi
mouse monoclonal (E-6)
  • immunocytochemistry; human; fig 4
Santa Cruz Biotechnology Prkdc antibody (SantaCruz, sc390698) was used in immunocytochemistry on human samples (fig 4). Oncotarget (2015) ncbi
Abcam
domestic rabbit monoclonal (Y393)
  • western blot; human; 1:1000; loading ...; fig 1f
Abcam Prkdc antibody (Abcam, ab32566) was used in western blot on human samples at 1:1000 (fig 1f). J Exp Clin Cancer Res (2021) ncbi
mouse monoclonal (18-2)
  • western blot; human; 1:500-1:2000; loading ...; fig 5c, 6e
Abcam Prkdc antibody (Abcam, ab44815) was used in western blot on human samples at 1:500-1:2000 (fig 5c, 6e). Cell Rep (2019) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig 3e
Abcam Prkdc antibody (Abcam, ab70250) was used in western blot on human samples at 1:1000 (fig 3e). Cell Rep (2018) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 6c
In order to use knockout mice to determine if GRK6 contributes to hematopoiesis, Abcam Prkdc antibody (Abcam, ab70250) was used in western blot on human samples (fig 6c). Cell Death Dis (2016) ncbi
domestic rabbit monoclonal (Y393)
  • western blot; human; loading ...; fig 4c
In order to study the effect of cathepsin L on glioma stem cells both in vivo and in vitro, Abcam Prkdc antibody (Abcam, ab32566) was used in western blot on human samples (fig 4c). Cancer Lett (2016) ncbi
domestic rabbit monoclonal (Y393)
  • western blot; human; 1:1000; fig 1g
In order to elucidate the function of TRIM29 in double stranded break repair, Abcam Prkdc antibody (Abcam, ab32566) was used in western blot on human samples at 1:1000 (fig 1g). Nat Commun (2015) ncbi
Invitrogen
mouse monoclonal (18-2)
  • western blot; human; 1:200; fig 4
In order to determine how PAXX interacts with Ku to promote DNA double-strand break repair, Invitrogen Prkdc antibody (Thermo Scientific, MS-369-P1) was used in western blot on human samples at 1:200 (fig 4). Science (2015) ncbi
mouse monoclonal (18-2)
  • western blot; human; 1:200; tbl 2
In order to develop a new method to visualize DNA double-strand break complexes, Invitrogen Prkdc antibody (Thermo Fisher, 18.2) was used in western blot on human samples at 1:200 (tbl 2). J Cell Biol (2013) ncbi
Articles Reviewed
  1. Lei X, Cao K, Chen Y, Shen H, Liu Z, Qin H, et al. Nuclear Transglutaminase 2 interacts with topoisomerase II⍺ to promote DNA damage repair in lung cancer cells. J Exp Clin Cancer Res. 2021;40:224 pubmed publisher
  2. Brunner A, Suryo Rahmanto A, Johansson H, Franco M, Viiliäinen J, Gazi M, et al. PTEN and DNA-PK determine sensitivity and recovery in response to WEE1 inhibition in human breast cancer. elife. 2020;9: pubmed publisher
  3. Zhu S, Paydar M, Wang F, Li Y, Wang L, Barrette B, et al. Kinesin Kif2C in regulation of DNA double strand break dynamics and repair. elife. 2020;9: pubmed publisher
  4. Wall C, Rose C, Adrian M, Zeng Y, Kirkpatrick D, Bingol B. PPEF2 Opposes PINK1-Mediated Mitochondrial Quality Control by Dephosphorylating Ubiquitin. Cell Rep. 2019;29:3280-3292.e7 pubmed publisher
  5. Tay L, Krishnan V, Sankar H, Chong Y, Chuang L, Tan T, et al. RUNX Poly(ADP-Ribosyl)ation and BLM Interaction Facilitate the Fanconi Anemia Pathway of DNA Repair. Cell Rep. 2018;24:1747-1755 pubmed publisher
  6. Squillaro T, Antonucci I, Alessio N, Esposito A, Cipollaro M, Melone M, et al. Impact of lysosomal storage disorders on biology of mesenchymal stem cells: Evidences from in vitro silencing of glucocerebrosidase (GBA) and alpha-galactosidase A (GLA) enzymes. J Cell Physiol. 2017;232:3454-3467 pubmed publisher
  7. Zhang H, Sun L, Wang K, Wu D, Trappio M, Witting C, et al. Loss of H3K9me3 Correlates with ATM Activation and Histone H2AX Phosphorylation Deficiencies in Hutchinson-Gilford Progeria Syndrome. PLoS ONE. 2016;11:e0167454 pubmed publisher
  8. Le Q, Yao W, Chen Y, Yan B, Liu C, Yuan M, et al. GRK6 regulates ROS response and maintains hematopoietic stem cell self-renewal. Cell Death Dis. 2016;7:e2478 pubmed publisher
  9. Wang W, Long L, Wang L, Tan C, Fei X, Chen L, et al. Knockdown of Cathepsin L promotes radiosensitivity of glioma stem cells both in vivo and in vitro. Cancer Lett. 2016;371:274-84 pubmed publisher
  10. Masuda Y, Takahashi H, Sato S, Tomomori Sato C, Saraf A, Washburn M, et al. TRIM29 regulates the assembly of DNA repair proteins into damaged chromatin. Nat Commun. 2015;6:7299 pubmed publisher
  11. Ochi T, Blackford A, Coates J, Jhujh S, Mehmood S, Tamura N, et al. DNA repair. PAXX, a paralog of XRCC4 and XLF, interacts with Ku to promote DNA double-strand break repair. Science. 2015;347:185-188 pubmed publisher
  12. Alessio N, Del Gaudio S, Capasso S, Di Bernardo G, Cappabianca S, Cipollaro M, et al. Low dose radiation induced senescence of human mesenchymal stromal cells and impaired the autophagy process. Oncotarget. 2015;6:8155-66 pubmed
  13. Britton S, Coates J, Jackson S. A new method for high-resolution imaging of Ku foci to decipher mechanisms of DNA double-strand break repair. J Cell Biol. 2013;202:579-95 pubmed publisher