This is a Validated Antibody Database (VAD) review about rat Prdx2, based on 8 published articles (read how Labome selects the articles), using Prdx2 antibody in all methods. It is aimed to help Labome visitors find the most suited Prdx2 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Prdx2 synonym: Tdpx1; peroxiredoxin-2; TSA; thiol-specific antioxidant protein; thioredoxin peroxidase 1; thioredoxin-dependent peroxide reductase 1

Abcam
mouse monoclonal (1E8)
  • western blot; mouse; loading ...; fig 4a
Abcam Prdx2 antibody (Abcam, ab50862) was used in western blot on mouse samples (fig 4a). J Biol Chem (2018) ncbi
rabbit monoclonal (EPR5154)
  • western blot; mouse; 1:250
Abcam Prdx2 antibody (Abcam, ab109367) was used in western blot on mouse samples at 1:250. J Proteomics (2015) ncbi
Invitrogen
mouse monoclonal (1E8)
  • western blot; mouse; 1:2000; loading ...; fig 5c
In order to determine if aldose reductase enzyme deficiency contributes to Parkinson's disease., Invitrogen Prdx2 antibody (LabFrontier, LF-MA0144) was used in western blot on mouse samples at 1:2000 (fig 5c). Neurobiol Aging (2017) ncbi
Proteintech Group
rabbit polyclonal
  • immunohistochemistry; mouse; fig 1
  • immunohistochemistry; human; fig 7
Proteintech Group Prdx2 antibody (Proteintech, 10545-2-AP) was used in immunohistochemistry on mouse samples (fig 1) and in immunohistochemistry on human samples (fig 7). Oncogene (2016) ncbi
Santa Cruz Biotechnology
mouse monoclonal (C-6)
  • western blot; human; 1:300; fig s4
Santa Cruz Biotechnology Prdx2 antibody (Santa Cruz, sc-271047) was used in western blot on human samples at 1:300 (fig s4). Redox Biol (2015) ncbi
Sigma-Aldrich
rabbit polyclonal
  • immunoprecipitation; human; loading ...; fig 1b
  • western blot; human; loading ...; fig 1b
Sigma-Aldrich Prdx2 antibody (sigma, R8656) was used in immunoprecipitation on human samples (fig 1b) and in western blot on human samples (fig 1b). Free Radic Biol Med (2018) ncbi
rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig 4a
Sigma-Aldrich Prdx2 antibody (Sigma-Aldrich, R8656) was used in western blot on mouse samples at 1:1000 (fig 4a). Free Radic Biol Med (2018) ncbi
rabbit polyclonal
  • western blot; rat; 1:20000
  • western blot; mouse; 1:20000
In order to investigate the mechanism for the neuroprotective effect of Klotho, Sigma-Aldrich Prdx2 antibody (Sigma-Aldrich, R8656) was used in western blot on rat samples at 1:20000 and in western blot on mouse samples at 1:20000. J Biol Chem (2014) ncbi
Articles Reviewed
  1. Pace P, Peskin A, Königstorfer A, Jasoni C, Winterbourn C, Hampton M. Peroxiredoxin interaction with the cytoskeletal-regulatory protein CRMP2: Investigation of a putative redox relay. Free Radic Biol Med. 2018;129:383-393 pubmed publisher
  2. Hinchy E, Gruszczyk A, Willows R, Navaratnam N, Hall A, Bates G, et al. Mitochondria-derived ROS activate AMP-activated protein kinase (AMPK) indirectly. J Biol Chem. 2018;293:17208-17217 pubmed publisher
  3. Chen W, Maghzal G, Ayer A, Suarna C, Dunn L, Stocker R. Absence of the biliverdin reductase-a gene is associated with increased endogenous oxidative stress. Free Radic Biol Med. 2018;115:156-165 pubmed publisher
  4. Yeung P, Lai A, Son H, Zhang X, Hwang O, Chung S, et al. Aldose reductase deficiency leads to oxidative stress-induced dopaminergic neuronal loss and autophagic abnormality in an animal model of Parkinson's disease. Neurobiol Aging. 2017;50:119-133 pubmed publisher
  5. Park Y, Kim S, Kwon T, Kim J, Song I, Shin H, et al. Peroxiredoxin II promotes hepatic tumorigenesis through cooperation with Ras/Forkhead box M1 signaling pathway. Oncogene. 2016;35:3503-13 pubmed publisher
  6. Bagulho A, Vilas Boas F, Pena A, Peneda C, Santos F, Jerónimo A, et al. The extracellular matrix modulates H2O2 degradation and redox signaling in endothelial cells. Redox Biol. 2015;6:454-60 pubmed publisher
  7. Viennois E, Baker M, Xiao B, Wang L, Laroui H, Merlin D. Longitudinal study of circulating protein biomarkers in inflammatory bowel disease. J Proteomics. 2015;112:166-79 pubmed publisher
  8. Zeldich E, Chen C, Colvin T, Bove Fenderson E, Liang J, Tucker Zhou T, et al. The neuroprotective effect of Klotho is mediated via regulation of members of the redox system. J Biol Chem. 2014;289:24700-15 pubmed publisher