This is a Validated Antibody Database (VAD) review about rat Ppp1cb, based on 4 published articles (read how Labome selects the articles), using Ppp1cb antibody in all methods. It is aimed to help Labome visitors find the most suited Ppp1cb antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Ppp1cb synonym: PP1B; PP1beta; serine/threonine-protein phosphatase PP1-beta catalytic subunit; PP-1B; protein phosphatase 1, catalytic subunit, beta isoform; protein phosphatase 1, catalytic subunit, beta isozyme; protein phosphatase-1a

Abcam
rabbit monoclonal (EP1804Y)
  • western blot; human; 1:1000; loading ...; fig 3d
Abcam Ppp1cb antibody (abcam, ab53315) was used in western blot on human samples at 1:1000 (fig 3d). Nat Commun (2018) ncbi
rabbit monoclonal (EP1804Y)
  • western blot; human; 1:50,000; loading ...; fig 1a
In order to investigate the effect of actomyosin on cell nuclear morphology and genome stability, Abcam Ppp1cb antibody (Abcam, ab53315) was used in western blot on human samples at 1:50,000 (fig 1a). Nat Commun (2017) ncbi
rabbit monoclonal (EP1804Y)
  • western blot; mouse; fig 3c
Abcam Ppp1cb antibody (Abcam, ab53315) was used in western blot on mouse samples (fig 3c). elife (2016) ncbi
Santa Cruz Biotechnology
mouse monoclonal (C-5)
  • western blot; human; loading ...; fig 1c
In order to determine specific residues on four MCM helicase subunits that show hyperphosphorylation upon RIF1 depletion, Santa Cruz Biotechnology Ppp1cb antibody (Santa Cruz, sc-373782) was used in western blot on human samples (fig 1c). EMBO Rep (2017) ncbi
Articles Reviewed
  1. Dingar D, Tu W, Resetca D, Lourenco C, Tamachi A, De Melo J, et al. MYC dephosphorylation by the PP1/PNUTS phosphatase complex regulates chromatin binding and protein stability. Nat Commun. 2018;9:3502 pubmed publisher
  2. Takaki T, Montagner M, Serres M, Le Berre M, Russell M, Collinson L, et al. Actomyosin drives cancer cell nuclear dysmorphia and threatens genome stability. Nat Commun. 2017;8:16013 pubmed publisher
  3. Hiraga S, Ly T, Garzón J, Horejsi Z, Ohkubo Y, Endo A, et al. Human RIF1 and protein phosphatase 1 stimulate DNA replication origin licensing but suppress origin activation. EMBO Rep. 2017;18:403-419 pubmed publisher
  4. Shin J, Kim T, Kim H, Kim H, Suh M, Lee S, et al. Aurkb/PP1-mediated resetting of Oct4 during the cell cycle determines the identity of embryonic stem cells. elife. 2016;5:e10877 pubmed publisher