This is a Validated Antibody Database (VAD) review about rat Ppp1ca, based on 23 published articles (read how Labome selects the articles), using Ppp1ca antibody in all methods. It is aimed to help Labome visitors find the most suited Ppp1ca antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Ppp1ca synonym: PP1alpha

Santa Cruz Biotechnology
mouse monoclonal (E-9)
  • western blot; human; loading ...; fig 5a
Santa Cruz Biotechnology Ppp1ca antibody (Santa Cruz Biotechnologies, sc-7482) was used in western blot on human samples (fig 5a). Cell Death Differ (2021) ncbi
mouse monoclonal (E-9)
  • western blot; mouse; 1:1000; loading ...
Santa Cruz Biotechnology Ppp1ca antibody (Santa Cruz Biotechnology, sc-7482) was used in western blot on mouse samples at 1:1000. Oncogenesis (2020) ncbi
mouse monoclonal (G-4)
  • western blot; mouse; loading ...; fig 5g
Santa Cruz Biotechnology Ppp1ca antibody (Santa, G-4) was used in western blot on mouse samples (fig 5g). J Clin Invest (2019) ncbi
mouse monoclonal (E-9)
  • western blot; mouse; loading ...; fig 5b
Santa Cruz Biotechnology Ppp1ca antibody (Santa, E-9) was used in western blot on mouse samples (fig 5b). J Clin Invest (2019) ncbi
mouse monoclonal (G-4)
  • western blot; human; loading ...; fig 1c
In order to determine specific residues on four MCM helicase subunits that show hyperphosphorylation upon RIF1 depletion, Santa Cruz Biotechnology Ppp1ca antibody (Santa Cruz, sc-271762) was used in western blot on human samples (fig 1c). EMBO Rep (2017) ncbi
mouse monoclonal (E-9)
  • western blot; human; loading ...; tbl 4
Santa Cruz Biotechnology Ppp1ca antibody (Santa Cruz, sc-7482) was used in western blot on human samples (tbl 4). Transl Psychiatry (2016) ncbi
mouse monoclonal (E-9)
  • western blot; rat; 1:1000; fig s1
In order to investigate left ventricular cardiomyocytes from post-infaction rats with and without heart failure after beta-adrenoceptor stimulation to revela Ca2+ waves and sarcoplasmic reticulum Ca2+ depletion, Santa Cruz Biotechnology Ppp1ca antibody (Santa Cruz Biotechnology, Sc-7482) was used in western blot on rat samples at 1:1000 (fig s1). PLoS ONE (2016) ncbi
mouse monoclonal (E-9)
  • western blot; human; fig s3
Santa Cruz Biotechnology Ppp1ca antibody (Santa Cruz, sc-7482) was used in western blot on human samples (fig s3). Genes Dev (2016) ncbi
mouse monoclonal (E-9)
  • immunoprecipitation; human; fig 4B
  • immunocytochemistry; human; fig 4E
  • western blot; human; fig 4B
Santa Cruz Biotechnology Ppp1ca antibody (Santa Cruz, sc-7482) was used in immunoprecipitation on human samples (fig 4B), in immunocytochemistry on human samples (fig 4E) and in western blot on human samples (fig 4B). Oncotarget (2016) ncbi
mouse monoclonal (E-9)
  • western blot; mouse; 1:3000; fig 3
Santa Cruz Biotechnology Ppp1ca antibody (Santa Cruz, sc7482) was used in western blot on mouse samples at 1:3000 (fig 3). Nat Commun (2015) ncbi
mouse monoclonal (E-9)
  • blocking or activating experiments; human; fig 5
In order to investigate the regulatory mechanism and role of ATG16L1 phosphorylation in autophagy induction using cardiomyocytes, Santa Cruz Biotechnology Ppp1ca antibody (Santa Cruz Biotechnology, SC-7482) was used in blocking or activating experiments on human samples (fig 5). Autophagy (2015) ncbi
mouse monoclonal (E-9)
  • immunoprecipitation; human; 1:2000; fig 1c
In order to show that Sephin1, a selective inhibitor of protein phosphatase 1, protects mice from protein-misfolding disease, Santa Cruz Biotechnology Ppp1ca antibody (Santa, sc-7482) was used in immunoprecipitation on human samples at 1:2000 (fig 1c). Science (2015) ncbi
mouse monoclonal (E-9)
  • western blot; human; 1:1000; fig s1
Santa Cruz Biotechnology Ppp1ca antibody (Santa Cruz, sc-7482) was used in western blot on human samples at 1:1000 (fig s1). Oncotarget (2015) ncbi
mouse monoclonal (E-9)
  • western blot; human
In order to study PDE3 in human cardiac myocytes, Santa Cruz Biotechnology Ppp1ca antibody (Santa Cruz, sc7482) was used in western blot on human samples . J Biol Chem (2015) ncbi
mouse monoclonal (E-9)
  • immunoprecipitation; rat; 1:300
  • western blot; rat
In order to report the signaling mechanisms by which PKC-zeta activation affects EMAP-II-induced BTB hyperpermeability, Santa Cruz Biotechnology Ppp1ca antibody (Santa Cruz, sc-7482) was used in immunoprecipitation on rat samples at 1:300 and in western blot on rat samples . Exp Cell Res (2015) ncbi
mouse monoclonal (E-9)
  • western blot; green monkey; 1:200
Santa Cruz Biotechnology Ppp1ca antibody (Santa, sc-7482) was used in western blot on green monkey samples at 1:200. J Virol (2014) ncbi
mouse monoclonal (E-9)
  • western blot; human; 1:1000; fig 7
Santa Cruz Biotechnology Ppp1ca antibody (Santa Cruz Biotechnology, sc-7482) was used in western blot on human samples at 1:1000 (fig 7). FEBS Lett (2014) ncbi
Abcam
domestic rabbit monoclonal (EP1512Y)
  • western blot; mouse; 1:30,000; loading ...; fig 3b
Abcam Ppp1ca antibody (Abcam, ab62334) was used in western blot on mouse samples at 1:30,000 (fig 3b). Development (2019) ncbi
domestic rabbit monoclonal (EP1511Y)
  • western blot; mouse; 1:1000; fig 3a
  • proximity ligation assay; human; 1:1000; loading ...; fig 2b
In order to show that PP1alpha inhibits the ubiquitin ligase Mdm2 by dephosphorylation to prevent its interaction with the mineralocorticoid receptor, Abcam Ppp1ca antibody (Abcam, ab52619) was used in western blot on mouse samples at 1:1000 (fig 3a) and in proximity ligation assay on human samples at 1:1000 (fig 2b). Mol Cell Endocrinol (2017) ncbi
Invitrogen
mouse monoclonal (10C6-3)
  • immunocytochemistry; human; fig 1
  • western blot; human; fig 1
In order to characterize an apical junctional complex with cytoskeletal associations and miRNA-mediated growth implications defined by PLEKHA7, Invitrogen Ppp1ca antibody (Invitrogen, 438100) was used in immunocytochemistry on human samples (fig 1) and in western blot on human samples (fig 1). Cell Cycle (2016) ncbi
mouse monoclonal (10C6-3)
  • western blot; human
In order to elucidate the contribution of lncRNA BCAR4 in breast cancer metastasis, Invitrogen Ppp1ca antibody (Life Technologies, 10C6.3) was used in western blot on human samples . Cell (2014) ncbi
Cell Signaling Technology
domestic rabbit polyclonal
  • immunohistochemistry; rat; loading ...; fig 3c
Cell Signaling Technology Ppp1ca antibody (Cell Signaling, 2581) was used in immunohistochemistry on rat samples (fig 3c). Cell Rep (2021) ncbi
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig s4h
Cell Signaling Technology Ppp1ca antibody (Cell Signaling, 2581) was used in western blot on mouse samples (fig s4h). PLoS Biol (2021) ncbi
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig s4h
Cell Signaling Technology Ppp1ca antibody (Cell Signaling, 2582) was used in western blot on mouse samples (fig s4h). PLoS Biol (2021) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 5f
Cell Signaling Technology Ppp1ca antibody (Cell Signaling, 2582) was used in western blot on human samples (fig 5f). Mol Oncol (2020) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 5f
Cell Signaling Technology Ppp1ca antibody (Cell Signaling, 2581) was used in western blot on human samples (fig 5f). Mol Oncol (2020) ncbi
Articles Reviewed
  1. Doré K, Carrico Z, Alfonso S, Marino M, Koymans K, Kessels H, et al. PSD-95 protects synapses from β-amyloid. Cell Rep. 2021;35:109194 pubmed publisher
  2. Grisan F, Iannucci L, Surdo N, Gerbino A, Zanin S, Di Benedetto G, et al. PKA compartmentalization links cAMP signaling and autophagy. Cell Death Differ. 2021;28:2436-2449 pubmed publisher
  3. Lu Y, Kavianpour S, Zhang T, Zhang X, Nguyen D, Thombre R, et al. MARK2 phosphorylates eIF2α in response to proteotoxic stress. PLoS Biol. 2021;19:e3001096 pubmed publisher
  4. Ailiken G, Kitamura K, Hoshino T, Satoh M, Tanaka N, Minamoto T, et al. Post-transcriptional regulation of BRG1 by FIRΔexon2 in gastric cancer. Oncogenesis. 2020;9:26 pubmed publisher
  5. Wang H, Chen Z, Wang S, Gao X, Qian M, Qiu W, et al. TGFβ1-induced beta-site APP-cleaving enzyme 2 upregulation promotes tumorigenesis through the NF-κB signalling pathway in human gliomas. Mol Oncol. 2020;14:407-425 pubmed publisher
  6. Loh J, Xu S, Huo J, Kim S, Wang Y, Lam K. Dok3-protein phosphatase 1 interaction attenuates Card9 signaling and neutrophil-dependent antifungal immunity. J Clin Invest. 2019;129:2717-2729 pubmed publisher
  7. Daldello E, Luong X, Yang C, Kuhn J, Conti M. Cyclin B2 is required for progression through meiosis in mouse oocytes. Development. 2019;146: pubmed publisher
  8. Nagarajan S, Vohra T, Loffing J, Faresse N. Protein Phosphatase 1α enhances renal aldosterone signaling via mineralocorticoid receptor stabilization. Mol Cell Endocrinol. 2017;450:74-82 pubmed publisher
  9. Hiraga S, Ly T, Garzón J, Horejsi Z, Ohkubo Y, Endo A, et al. Human RIF1 and protein phosphatase 1 stimulate DNA replication origin licensing but suppress origin activation. EMBO Rep. 2017;18:403-419 pubmed publisher
  10. Lopes M, Leal R, Guarnieri R, Schwarzbold M, Hoeller A, Diaz A, et al. A single high dose of dexamethasone affects the phosphorylation state of glutamate AMPA receptors in the human limbic system. Transl Psychiatry. 2016;6:e986 pubmed publisher
  11. Sadredini M, Danielsen T, Aronsen J, Manotheepan R, Hougen K, Sjaastad I, et al. Beta-Adrenoceptor Stimulation Reveals Ca2+ Waves and Sarcoplasmic Reticulum Ca2+ Depletion in Left Ventricular Cardiomyocytes from Post-Infarction Rats with and without Heart Failure. PLoS ONE. 2016;11:e0153887 pubmed publisher
  12. Kourtidis A, Anastasiadis P. PLEKHA7 defines an apical junctional complex with cytoskeletal associations and miRNA-mediated growth implications. Cell Cycle. 2016;15:498-505 pubmed publisher
  13. Sansó M, Levin R, Lipp J, Wang V, Greifenberg A, Quezada E, et al. P-TEFb regulation of transcription termination factor Xrn2 revealed by a chemical genetic screen for Cdk9 substrates. Genes Dev. 2016;30:117-31 pubmed publisher
  14. Wang Z, Ma B, Li H, Xiao X, Zhou W, Liu F, et al. Protein 4.1N acts as a potential tumor suppressor linking PP1 to JNK-c-Jun pathway regulation in NSCLC. Oncotarget. 2016;7:509-23 pubmed publisher
  15. Wong P, Feng Y, Wang J, Shi R, Jiang X. Regulation of autophagy by coordinated action of mTORC1 and protein phosphatase 2A. Nat Commun. 2015;6:8048 pubmed publisher
  16. Song H, Pu J, Wang L, Wu L, Xiao J, Liu Q, et al. ATG16L1 phosphorylation is oppositely regulated by CSNK2/casein kinase 2 and PPP1/protein phosphatase 1 which determines the fate of cardiomyocytes during hypoxia/reoxygenation. Autophagy. 2015;11:1308-25 pubmed publisher
  17. Das I, Krzyzosiak A, Schneider K, Wrabetz L, D Antonio M, Barry N, et al. Preventing proteostasis diseases by selective inhibition of a phosphatase regulatory subunit. Science. 2015;348:239-42 pubmed publisher
  18. Li G, Zhou J, Budhraja A, Hu X, Chen Y, Cheng Q, et al. Mitochondrial translocation and interaction of cofilin and Drp1 are required for erucin-induced mitochondrial fission and apoptosis. Oncotarget. 2015;6:1834-49 pubmed
  19. Ahmad F, Shen W, Vandeput F, Szabo Fresnais N, Krall J, Degerman E, et al. Regulation of sarcoplasmic reticulum Ca2+ ATPase 2 (SERCA2) activity by phosphodiesterase 3A (PDE3A) in human myocardium: phosphorylation-dependent interaction of PDE3A1 with SERCA2. J Biol Chem. 2015;290:6763-76 pubmed publisher
  20. Li Z, Liu Y, Liu X, Xue Y, Wang P, Liu L. Low-dose endothelial monocyte-activating polypeptide-II increases permeability of blood-tumor barrier via a PKC-ζ/PP2A-dependent signaling mechanism. Exp Cell Res. 2015;331:257-66 pubmed publisher
  21. Xing Z, Lin A, Li C, Liang K, Wang S, Liu Y, et al. lncRNA directs cooperative epigenetic regulation downstream of chemokine signals. Cell. 2014;159:1110-1125 pubmed publisher
  22. Jamin A, Wicklund A, Wiebe M. Cell- and virus-mediated regulation of the barrier-to-autointegration factor's phosphorylation state controls its DNA binding, dimerization, subcellular localization, and antipoxviral activity. J Virol. 2014;88:5342-55 pubmed publisher
  23. Amsailale R, Beyaert M, Smal C, Janssens V, Van Den Neste E, Bontemps F. Protein phosphatase 2A regulates deoxycytidine kinase activity via Ser-74 dephosphorylation. FEBS Lett. 2014;588:727-32 pubmed publisher