This is a Validated Antibody Database (VAD) review about rat Pmaip1, based on 15 published articles (read how Labome selects the articles), using Pmaip1 antibody in all methods. It is aimed to help Labome visitors find the most suited Pmaip1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Pmaip1 synonym: Noxa; phorbol-12-myristate-13-acetate-induced protein 1; protein Noxa

Knockout validation
ProSci
rabbit polyclonal
  • western blot knockout validation; mouse; fig 2
ProSci Pmaip1 antibody (ProSci, 2437) was used in western blot knockout validation on mouse samples (fig 2). Cell Death Dis (2016) ncbi
Invitrogen
mouse monoclonal (114C307.1)
  • western blot; human; loading ...; fig 2c
In order to explore the role of chaperone-mediated autophagy in non-small-cell lung cancer, Invitrogen Pmaip1 antibody (Thermo Fisher, 114C307.1) was used in western blot on human samples (fig 2c). Biochem Biophys Res Commun (2017) ncbi
mouse monoclonal (114C307.1)
  • western blot; human; loading ...; fig 1b
In order to report that Noxa-mediated MCL-1 phosphorylation and subsequent MCL-1 degradation is critical for DNA damaging agent-induced apoptosis, Invitrogen Pmaip1 antibody (Thermo Fisher, 114C307.1) was used in western blot on human samples (fig 1b). Oncotarget (2016) ncbi
mouse monoclonal (114C307.1)
  • western blot; human; loading ...; fig 1a
In order to elucidate the mechanism of cisplatin-induced non-small-cell lung cancer cell apoptosis, Invitrogen Pmaip1 antibody (Thermo Fisher, 114C307.1) was used in western blot on human samples (fig 1a). Biochem Biophys Res Commun (2016) ncbi
mouse monoclonal (114C307.1)
  • western blot; human; loading ...; fig 1
In order to study the effects of HDAC inhibitors and BCL-2 inhibitors on small cell lung cancer lines, Invitrogen Pmaip1 antibody (Thermo Fisher, 114C307.1) was used in western blot on human samples (fig 1). Cancer Biol Ther (2016) ncbi
mouse monoclonal (114C307.1)
  • western blot; human
In order to evaluate the effect of Noxa on the localization and stability of MCL-1 in small cell lung cancer, Invitrogen Pmaip1 antibody (Thermo Fisher Scientific, 114C307.1) was used in western blot on human samples . Cell Death Dis (2014) ncbi
EMD Millipore
mouse monoclonal
  • western blot; human; fig s3
In order to report that cathepsin S inhibition sensitizes cancer cells to tumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis, EMD Millipore Pmaip1 antibody (Millipore, OP180) was used in western blot on human samples (fig s3). Antioxid Redox Signal (2017) ncbi
mouse monoclonal
  • western blot; human; 1:200; loading ...; fig s6d
EMD Millipore Pmaip1 antibody (Calbiochem, OP180) was used in western blot on human samples at 1:200 (fig s6d). Nat Cell Biol (2016) ncbi
mouse monoclonal
  • western blot; human; fig 2
In order to identify the mechanism for apoptosis in colon cancer cells after depletion of PTEN, EMD Millipore Pmaip1 antibody (Calbiochem, OP180) was used in western blot on human samples (fig 2). PLoS ONE (2015) ncbi
mouse monoclonal
  • western blot; mouse; fig 9a
EMD Millipore Pmaip1 antibody (EMD Millipore, OP180) was used in western blot on mouse samples (fig 9a). J Cell Biol (2015) ncbi
mouse monoclonal
  • western blot; human; fig 7
EMD Millipore Pmaip1 antibody (EMD Chemicals, OP180) was used in western blot on human samples (fig 7). J Biol Chem (2015) ncbi
ProSci
rabbit polyclonal
  • western blot knockout validation; mouse; fig 2
ProSci Pmaip1 antibody (ProSci, 2437) was used in western blot knockout validation on mouse samples (fig 2). Cell Death Dis (2016) ncbi
rabbit polyclonal
  • western blot; human; fig 5
ProSci Pmaip1 antibody (ProSci Inc, 2437) was used in western blot on human samples (fig 5). Oncogene (2015) ncbi
rabbit polyclonal
  • western blot; mouse
  • western blot; rat
  • western blot; human
ProSci Pmaip1 antibody (ProSci, 2437) was used in western blot on mouse samples , in western blot on rat samples and in western blot on human samples . J Neurosci (2014) ncbi
rabbit polyclonal
  • western blot; mouse
ProSci Pmaip1 antibody (ProSci Inc, 2437) was used in western blot on mouse samples . Eur J Immunol (2011) ncbi
Sigma-Aldrich
rabbit polyclonal
  • western blot; kangaroo rats; 1:500; fig 5
Sigma-Aldrich Pmaip1 antibody (sigma, PRS2437) was used in western blot on kangaroo rats samples at 1:500 (fig 5). Cell Mol Neurobiol (2015) ncbi
Articles Reviewed
  1. Suzuki J, Nakajima W, Suzuki H, Asano Y, Tanaka N. Chaperone-mediated autophagy promotes lung cancer cell survival through selective stabilization of the pro-survival protein, MCL1. Biochem Biophys Res Commun. 2017;482:1334-1340 pubmed publisher
  2. Seo B, Min K, Woo S, Choe M, Choi K, Lee Y, et al. Inhibition of Cathepsin S Induces Mitochondrial ROS That Sensitizes TRAIL-Mediated Apoptosis Through p53-Mediated Downregulation of Bcl-2 and c-FLIP. Antioxid Redox Signal. 2017;27:215-233 pubmed publisher
  3. Bilardi R, Anstee N, Glaser S, Robati M, Vandenberg C, Cory S. Impact of loss of BH3-only proteins on the development and treatment of MLL-fusion gene-driven AML in mice. Cell Death Dis. 2016;7:e2351 pubmed publisher
  4. Walerych D, Lisek K, Sommaggio R, Piazza S, Ciani Y, Dalla E, et al. Proteasome machinery is instrumental in a common gain-of-function program of the p53 missense mutants in cancer. Nat Cell Biol. 2016;18:897-909 pubmed publisher
  5. Nakajima W, Sharma K, Lee J, Maxim N, Hicks M, Vu T, et al. DNA damaging agent-induced apoptosis is regulated by MCL-1 phosphorylation and degradation mediated by the Noxa/MCL-1/CDK2 complex. Oncotarget. 2016;7:36353-36365 pubmed publisher
  6. Matsumoto M, Nakajima W, Seike M, Gemma A, Tanaka N. Cisplatin-induced apoptosis in non-small-cell lung cancer cells is dependent on Bax- and Bak-induction pathway and synergistically activated by BH3-mimetic ABT-263 in p53 wild-type and mutant cells. Biochem Biophys Res Commun. 2016;473:490-6 pubmed publisher
  7. Nakajima W, Sharma K, Hicks M, Le N, Brown R, Krystal G, et al. Combination with vorinostat overcomes ABT-263 (navitoclax) resistance of small cell lung cancer. Cancer Biol Ther. 2016;17:27-35 pubmed publisher
  8. Lauková J, Kozubík A, Hofmanová J, Nekvindová J, Sova P, Moyer M, et al. Loss of PTEN Facilitates Rosiglitazone-Mediated Enhancement of Platinum(IV) Complex LA-12-Induced Apoptosis in Colon Cancer Cells. PLoS ONE. 2015;10:e0141020 pubmed publisher
  9. Xie C, Wei D, Zhao L, Marchetto S, Mei L, Borg J, et al. Erbin is a novel substrate of the Sag-βTrCP E3 ligase that regulates KrasG12D-induced skin tumorigenesis. J Cell Biol. 2015;209:721-37 pubmed publisher
  10. Long J, Schoonen P, Graczyk D, O Prey J, Ryan K. p73 engages A2B receptor signalling to prime cancer cells to chemotherapy-induced death. Oncogene. 2015;34:5152-62 pubmed publisher
  11. Davis A, Qiao S, Lesson J, Rojo de la Vega M, Park S, Seanez C, et al. The quinone methide aurin is a heat shock response inducer that causes proteotoxic stress and Noxa-dependent apoptosis in malignant melanoma cells. J Biol Chem. 2015;290:1623-38 pubmed publisher
  12. Pilchova I, Klacanova K, Chomova M, Tatarkova Z, Dobrota D, Racay P. Possible contribution of proteins of Bcl-2 family in neuronal death following transient global brain ischemia. Cell Mol Neurobiol. 2015;35:23-31 pubmed publisher
  13. Sabirzhanov B, Zhao Z, Stoica B, Loane D, Wu J, Borroto C, et al. Downregulation of miR-23a and miR-27a following experimental traumatic brain injury induces neuronal cell death through activation of proapoptotic Bcl-2 proteins. J Neurosci. 2014;34:10055-71 pubmed publisher
  14. Nakajima W, Hicks M, Tanaka N, Krystal G, Harada H. Noxa determines localization and stability of MCL-1 and consequently ABT-737 sensitivity in small cell lung cancer. Cell Death Dis. 2014;5:e1052 pubmed publisher
  15. O Brien T, Gorentla B, Xie D, Srivatsan S, McLeod I, He Y, et al. Regulation of T-cell survival and mitochondrial homeostasis by TSC1. Eur J Immunol. 2011;41:3361-70 pubmed publisher