This is a Validated Antibody Database (VAD) review about rat Pik3r1, based on 61 published articles (read how Labome selects the articles), using Pik3r1 antibody in all methods. It is aimed to help Labome visitors find the most suited Pik3r1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Pik3r1 synonym: PI3KA

Santa Cruz Biotechnology
mouse monoclonal (B-9)
  • western blot; human; 1:1000; loading ...; fig 3b
Santa Cruz Biotechnology Pik3r1 antibody (Santa Cruz Biotechnology, sc-1637) was used in western blot on human samples at 1:1000 (fig 3b). Anal Cell Pathol (Amst) (2019) ncbi
mouse monoclonal (2B2.79)
  • western blot; human; loading ...; fig 5a
Santa Cruz Biotechnology Pik3r1 antibody (SantaCruz, sc-71891) was used in western blot on human samples (fig 5a). Lab Invest (2017) ncbi
mouse monoclonal (B-9)
  • western blot; human; loading ...; fig 6A
Santa Cruz Biotechnology Pik3r1 antibody (Santa Cruz, sc-1637) was used in western blot on human samples (fig 6A). Sci Rep (2017) ncbi
mouse monoclonal (B-9)
  • western blot; mouse; loading ...; fig 1e
In order to determine if PIK3CA mutations contribute to tumor initiation, Santa Cruz Biotechnology Pik3r1 antibody (Santa Cruz, sc-1637) was used in western blot on mouse samples (fig 1e). Oncogenesis (2016) ncbi
mouse monoclonal (B-9)
  • western blot; mouse; loading ...; fig 1a
Santa Cruz Biotechnology Pik3r1 antibody (Santa Cruz, B-9) was used in western blot on mouse samples (fig 1a). Diabetes (2016) ncbi
mouse monoclonal (2B2.79)
  • western blot; mouse; loading ...; fig 2a
In order to determine the role of forkhead box O1 in cannabinoid receptor type-mediated insulin resistance, Santa Cruz Biotechnology Pik3r1 antibody (Santa Cruz, 71891) was used in western blot on mouse samples (fig 2a). Int J Mol Med (2016) ncbi
mouse monoclonal (B-9)
  • western blot; human; 1:200; fig 4
Santa Cruz Biotechnology Pik3r1 antibody (Santa Cruz, sc-1637) was used in western blot on human samples at 1:200 (fig 4). Mol Med Rep (2015) ncbi
mouse monoclonal (C-1)
  • immunoprecipitation; human; fig 5
  • immunohistochemistry; human; fig 1
  • western blot; human; fig 2
Santa Cruz Biotechnology Pik3r1 antibody (Santa Cruz, sc-376112) was used in immunoprecipitation on human samples (fig 5), in immunohistochemistry on human samples (fig 1) and in western blot on human samples (fig 2). Sci Rep (2015) ncbi
mouse monoclonal (B-9)
  • western blot; chicken
In order to study the oncogenic effects of regulatory subunit p85beta of PI3K using primary avian fibroblasts, Santa Cruz Biotechnology Pik3r1 antibody (Santa Cruz, SC-1637) was used in western blot on chicken samples . Proc Natl Acad Sci U S A (2014) ncbi
mouse monoclonal (B-9)
  • western blot; mouse
Santa Cruz Biotechnology Pik3r1 antibody (Santa Cruz Biotechnology, Sc-1637) was used in western blot on mouse samples . Amino Acids (2014) ncbi
mouse monoclonal (B-9)
  • western blot; human
Santa Cruz Biotechnology Pik3r1 antibody (Santa cruz, sc-1637) was used in western blot on human samples . Biochem Biophys Res Commun (2014) ncbi
mouse monoclonal (B-9)
  • western blot; mouse; fig 9
Santa Cruz Biotechnology Pik3r1 antibody (Santa Cruz Biotechnology, sc-1637) was used in western blot on mouse samples (fig 9). Biochemistry (2013) ncbi
mouse monoclonal (B-9)
  • western blot; human
Santa Cruz Biotechnology Pik3r1 antibody (Santa Cruz Biotechnology, SC-1637) was used in western blot on human samples . Int J Biochem Cell Biol (2013) ncbi
mouse monoclonal (B-9)
  • western blot; human
In order to determine how HER2/HER3 regulates extracellular acidification and cell migration, Santa Cruz Biotechnology Pik3r1 antibody (Santa Cruz Biotechnology, sc-1637) was used in western blot on human samples . Cell Signal (2014) ncbi
mouse monoclonal (B-9)
  • western blot; human; fig 3
Santa Cruz Biotechnology Pik3r1 antibody (Santa Cruz Biotechnology, sc-1637) was used in western blot on human samples (fig 3). Evid Based Complement Alternat Med (2013) ncbi
Abcam
domestic rabbit monoclonal (EPR18702)
  • western blot; human; 1:1000; loading ...; fig 5b
  • western blot; mouse; 1:1000; loading ...; fig 5a
Abcam Pik3r1 antibody (Abcam, ab191606) was used in western blot on human samples at 1:1000 (fig 5b) and in western blot on mouse samples at 1:1000 (fig 5a). Aging (Albany NY) (2019) ncbi
domestic rabbit monoclonal (EPR18702)
  • western blot; human; loading ...; fig 7a
Abcam Pik3r1 antibody (Abcam, ab191606) was used in western blot on human samples (fig 7a). Cell Physiol Biochem (2018) ncbi
domestic rabbit monoclonal (EPR18702)
  • immunohistochemistry - paraffin section; mouse; 1:100; loading ...; fig 2a
  • western blot; mouse; 1:1000; loading ...; fig 10a
Abcam Pik3r1 antibody (BIOSS, ab191606) was used in immunohistochemistry - paraffin section on mouse samples at 1:100 (fig 2a) and in western blot on mouse samples at 1:1000 (fig 10a). Oncol Rep (2018) ncbi
domestic rabbit monoclonal (EPR5513)
  • western blot; mouse; fig 8
Abcam Pik3r1 antibody (CST, 5405-1) was used in western blot on mouse samples (fig 8). Sci Rep (2016) ncbi
domestic rabbit monoclonal (ep380y)
  • western blot; rat; fig 4
Abcam Pik3r1 antibody (abcam, ab40755) was used in western blot on rat samples (fig 4). Int J Mol Sci (2016) ncbi
domestic rabbit monoclonal (ep380y)
  • immunohistochemistry - paraffin section; human; loading ...; tbl 4
Abcam Pik3r1 antibody (Abcam, Ab 40755) was used in immunohistochemistry - paraffin section on human samples (tbl 4). Chin J Cancer (2016) ncbi
domestic rabbit monoclonal (ep380y)
  • immunohistochemistry - paraffin section; human; loading ...; fig 5a, b
Abcam Pik3r1 antibody (Abcam, ab40755) was used in immunohistochemistry - paraffin section on human samples (fig 5a, b). Int J Oncol (2016) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (19H8)
  • western blot; human; loading ...; fig s1f
Cell Signaling Technology Pik3r1 antibody (Cell Signaling, 4257) was used in western blot on human samples (fig s1f). Cell (2019) ncbi
domestic rabbit monoclonal (19H8)
  • western blot; human; loading ...; fig 5a
Cell Signaling Technology Pik3r1 antibody (Cell Signaling, 19H8) was used in western blot on human samples (fig 5a). J Exp Med (2019) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:500; loading ...; fig 1d
Cell Signaling Technology Pik3r1 antibody (Cell Signaling, 4292) was used in western blot on human samples at 1:500 (fig 1d). J Huntingtons Dis (2019) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 6f
Cell Signaling Technology Pik3r1 antibody (Cell Signaling, 4292) was used in western blot on human samples (fig 6f). Cell Rep (2018) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig 2a
Cell Signaling Technology Pik3r1 antibody (Cell Signaling, 4292) was used in western blot on mouse samples at 1:1000 (fig 2a). Basic Clin Pharmacol Toxicol (2018) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:2000; loading ...; fig 7a
Cell Signaling Technology Pik3r1 antibody (Cell signaling, 4292) was used in western blot on human samples at 1:2000 (fig 7a). J Exp Clin Cancer Res (2017) ncbi
domestic rabbit monoclonal (19H8)
  • western blot; mouse; 1:1000; loading ...; fig 3c
Cell Signaling Technology Pik3r1 antibody (cell signaling, 4257) was used in western blot on mouse samples at 1:1000 (fig 3c). Oncogene (2017) ncbi
domestic rabbit monoclonal (19H8)
  • western blot; human; fig 4a
Cell Signaling Technology Pik3r1 antibody (Cell Signalling Technology, 4257) was used in western blot on human samples (fig 4a). DNA Cell Biol (2017) ncbi
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig 1a
Cell Signaling Technology Pik3r1 antibody (Cell Signaling Technology, 4292s) was used in western blot on mouse samples (fig 1a). Diabetes (2017) ncbi
domestic rabbit monoclonal (19H8)
  • western blot; human; loading ...; fig 5a
Cell Signaling Technology Pik3r1 antibody (Cell Signaling Technology, 4257) was used in western blot on human samples (fig 5a). FEBS Open Bio (2017) ncbi
domestic rabbit monoclonal (19H8)
  • western blot; mouse; 1:1000; loading ...; fig s9a
In order to discuss how NLRC3 protects against colorectal cancer by modulating mTor signaling, Cell Signaling Technology Pik3r1 antibody (Cell Signaling, 4257) was used in western blot on mouse samples at 1:1000 (fig s9a). Nature (2016) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; mouse; loading ...
In order to clarify the impact of PI3K and PKA signaling to tongue epithelial differentiation, Cell Signaling Technology Pik3r1 antibody (Cell Signaling, 4292) was used in immunohistochemistry - paraffin section on mouse samples . Acta Histochem (2017) ncbi
domestic rabbit monoclonal (19H8)
  • western blot; human; loading ...; fig 6d
Cell Signaling Technology Pik3r1 antibody (Cell signaling, 4257) was used in western blot on human samples (fig 6d). J Exp Clin Cancer Res (2016) ncbi
domestic rabbit monoclonal (19H8)
  • western blot; mouse; loading ...; fig 7a
Cell Signaling Technology Pik3r1 antibody (Cell Signaling, 4257) was used in western blot on mouse samples (fig 7a). Int J Mol Med (2016) ncbi
domestic rabbit monoclonal (19H8)
  • western blot; rat; 1:1000; loading ...; fig 2
In order to measure brain insulin signaling in response to dexamethasone treatment in female Charles Foster rats, Cell Signaling Technology Pik3r1 antibody (Cell Signaling, 4257) was used in western blot on rat samples at 1:1000 (fig 2). Mol Neurobiol (2017) ncbi
domestic rabbit monoclonal (19H8)
  • western blot; Spodoptera litura; fig 3a
Cell Signaling Technology Pik3r1 antibody (Cell Signaling, 4257) was used in western blot on Spodoptera litura samples (fig 3a). Sci Rep (2016) ncbi
domestic rabbit monoclonal (19H8)
  • western blot; human; 1:1000; loading ...; fig 4f
Cell Signaling Technology Pik3r1 antibody (Cell Signaling, 4257) was used in western blot on human samples at 1:1000 (fig 4f). Oncotarget (2016) ncbi
domestic rabbit polyclonal
In order to evaluate the effects of epicatechin in the normal heart, Cell Signaling Technology Pik3r1 antibody (Cell Signaling, 4292) was used . Mol Nutr Food Res (2017) ncbi
domestic rabbit monoclonal (19H8)
  • western blot; rat; fig 2
Cell Signaling Technology Pik3r1 antibody (Cell Signaling, 4257) was used in western blot on rat samples (fig 2). Int J Mol Med (2016) ncbi
domestic rabbit polyclonal
  • immunoprecipitation; mouse; fig 5
  • western blot; mouse; fig 5
Cell Signaling Technology Pik3r1 antibody (Cell Signaling Tech, 4292) was used in immunoprecipitation on mouse samples (fig 5) and in western blot on mouse samples (fig 5). Mol Syst Biol (2016) ncbi
domestic rabbit monoclonal (19H8)
  • western blot; mouse; 1:500; fig 6
In order to study the attenuation of Alzheimer's pathology in mice due to kallikrein-8 inhibition, Cell Signaling Technology Pik3r1 antibody (Cell Signaling Technology, 4257) was used in western blot on mouse samples at 1:500 (fig 6). Alzheimers Dement (2016) ncbi
domestic rabbit monoclonal (19H8)
  • western blot; human; loading ...; fig 1a
Cell Signaling Technology Pik3r1 antibody (Cell Signaling, 4257) was used in western blot on human samples (fig 1a). Oncotarget (2016) ncbi
domestic rabbit monoclonal (19H8)
  • western blot; human; fig 1
Cell Signaling Technology Pik3r1 antibody (Cell Signaling, 4257) was used in western blot on human samples (fig 1). J Immunol (2016) ncbi
domestic rabbit monoclonal (19H8)
  • western blot; mouse; 1:1000; fig 6
Cell Signaling Technology Pik3r1 antibody (Cell Signaling, 4257) was used in western blot on mouse samples at 1:1000 (fig 6). Sci Rep (2016) ncbi
domestic rabbit monoclonal (19H8)
  • western blot; human; fig 6
In order to characterize induction of apoptosis in SH-SY5Y human neuroblastoma cells through up regulation of flotillin-2 in the lipid raft and the activation of BDNF/Trkb signaling due to cholesterol overload, Cell Signaling Technology Pik3r1 antibody (Cell Signaling Technology, 4257) was used in western blot on human samples (fig 6). Neuroscience (2016) ncbi
domestic rabbit monoclonal (19H8)
  • western blot; mouse; fig 6
Cell Signaling Technology Pik3r1 antibody (Cell Signaling, 4257) was used in western blot on mouse samples (fig 6). Oncotarget (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; fig 1
Cell Signaling Technology Pik3r1 antibody (Cell Signaling, 4292S) was used in western blot on human samples (fig 1). Sci Rep (2016) ncbi
domestic rabbit monoclonal (19H8)
  • western blot; human; fig 5
Cell Signaling Technology Pik3r1 antibody (Cell Signaling Tech, 4257) was used in western blot on human samples (fig 5). PLoS Pathog (2016) ncbi
domestic rabbit monoclonal (19H8)
  • western blot; human; fig 6
Cell Signaling Technology Pik3r1 antibody (Cell Signaling, 4257) was used in western blot on human samples (fig 6). Sci Rep (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; fig 6
Cell Signaling Technology Pik3r1 antibody (Cell Signaling Technology, 4292) was used in western blot on human samples (fig 6). Sci Rep (2016) ncbi
domestic rabbit polyclonal
  • western blot; mouse; fig 4
Cell Signaling Technology Pik3r1 antibody (CST, 4292) was used in western blot on mouse samples (fig 4). Stem Cell Reports (2016) ncbi
domestic rabbit monoclonal (19H8)
  • western blot; human; fig 4b
Cell Signaling Technology Pik3r1 antibody (Cell Signaling Technology, 4257) was used in western blot on human samples (fig 4b). Oncogene (2016) ncbi
domestic rabbit monoclonal (19H8)
  • western blot; human; loading ...; fig 5e
Cell Signaling Technology Pik3r1 antibody (Cell Signaling, 4257) was used in western blot on human samples (fig 5e). BMC Cancer (2015) ncbi
domestic rabbit monoclonal (19H8)
  • western blot; human; fig 3
Cell Signaling Technology Pik3r1 antibody (Cell Signaling, 4257) was used in western blot on human samples (fig 3). EBioMedicine (2015) ncbi
domestic rabbit monoclonal (19H8)
  • western blot; human; 1:1000
Cell Signaling Technology Pik3r1 antibody (Cell Signaling, 4257s) was used in western blot on human samples at 1:1000. Am J Physiol Endocrinol Metab (2015) ncbi
domestic rabbit monoclonal (19H8)
  • western blot; human; 1:800; fig 5
Cell Signaling Technology Pik3r1 antibody (Cell Signaling, 4257) was used in western blot on human samples at 1:800 (fig 5). PLoS ONE (2015) ncbi
EMD Millipore
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 4c
EMD Millipore Pik3r1 antibody (Millipore, ABS233) was used in western blot on human samples (fig 4c). Front Immunol (2019) ncbi
domestic rabbit polyclonal
  • immunoprecipitation; mouse; loading ...; fig 6a
  • western blot; mouse; loading ...; fig 6a
EMD Millipore Pik3r1 antibody (Millipore, ABS234) was used in immunoprecipitation on mouse samples (fig 6a) and in western blot on mouse samples (fig 6a). Sci Signal (2018) ncbi
domestic rabbit polyclonal
  • immunoprecipitation; mouse; fig 6
  • western blot; mouse; fig 5
EMD Millipore Pik3r1 antibody (Millipore, ABS233) was used in immunoprecipitation on mouse samples (fig 6) and in western blot on mouse samples (fig 5). J Clin Invest (2016) ncbi
Articles Reviewed
  1. Long R, Liu Z, Li J, Yu H. COL6A6 interacted with P4HA3 to suppress the growth and metastasis of pituitary adenoma via blocking PI3K-Akt pathway. Aging (Albany NY). 2019;11:8845-8859 pubmed publisher
  2. Lundby A, Franciosa G, Emdal K, Refsgaard J, Gnosa S, Bekker Jensen D, et al. Oncogenic Mutations Rewire Signaling Pathways by Switching Protein Recruitment to Phosphotyrosine Sites. Cell. 2019;179:543-560.e26 pubmed publisher
  3. El Kott A, Shati A, Al Kahtani M, Alqahtani S. Acylated Ghrelin Renders Chemosensitive Ovarian Cancer Cells Resistant to Cisplatin Chemotherapy via Activation of the PI3K/Akt/mTOR Survival Pathway. Anal Cell Pathol (Amst). 2019;2019:9627810 pubmed publisher
  4. Fenwick C, Loredo Varela J, Joo V, Pellaton C, Farina A, Rajah N, et al. Tumor suppression of novel anti-PD-1 antibodies mediated through CD28 costimulatory pathway. J Exp Med. 2019;: pubmed publisher
  5. Thauland T, Pellerin L, Ohgami R, Bacchetta R, Butte M. Case Study: Mechanism for Increased Follicular Helper T Cell Development in Activated PI3K Delta Syndrome. Front Immunol. 2019;10:753 pubmed publisher
  6. Tousley A, Iuliano M, Weisman E, Sapp E, Zhang N, Vodicka P, et al. Rac1 Activity Is Modulated by Huntingtin and Dysregulated in Models of Huntington's Disease. J Huntingtons Dis. 2019;8:53-69 pubmed publisher
  7. Roy N, MacKay J, Robertson T, Hammer D, Burkhardt J. Crk adaptor proteins mediate actin-dependent T cell migration and mechanosensing induced by the integrin LFA-1. Sci Signal. 2018;11: pubmed publisher
  8. Yin D, Li Y, Fu C, Feng Y. Pro-Angiogenic Role of LncRNA HULC in Microvascular Endothelial Cells via Sequestrating miR-124. Cell Physiol Biochem. 2018;50:2188-2202 pubmed publisher
  9. Chen Y, Huang Y, Lu X, Wang G, Chi P. Antitumor effects of the silencing of programmed cell death ligand 1 in colorectal cancer via immunoregulation. Oncol Rep. 2018;40:3370-3380 pubmed publisher
  10. Zhao Y, Harrison D, Song Y, Ji J, Huang J, Hui E. Antigen-Presenting Cell-Intrinsic PD-1 Neutralizes PD-L1 in cis to Attenuate PD-1 Signaling in T Cells. Cell Rep. 2018;24:379-390.e6 pubmed publisher
  11. Urbschat A, Baer P, Zacharowski K, Sprunck V, Scheller B, Raimann F, et al. Systemic TLR2 Antibody Application in Renal Ischaemia and Reperfusion Injury Decreases AKT Phosphorylation and Increases Apoptosis in the Mouse Kidney. Basic Clin Pharmacol Toxicol. 2018;122:223-232 pubmed publisher
  12. Yu L, Sun Y, Li J, Wang Y, Zhu Y, Shi Y, et al. Silencing the Girdin gene enhances radio-sensitivity of hepatocellular carcinoma via suppression of glycolytic metabolism. J Exp Clin Cancer Res. 2017;36:110 pubmed publisher
  13. Simond A, Rao T, Zuo D, Zhao J, Muller W. ErbB2-positive mammary tumors can escape PI3K-p110α loss through downregulation of the Pten tumor suppressor. Oncogene. 2017;36:6059-6066 pubmed publisher
  14. Liu X, Zhou X, Xu H, He Z, Shi X, Wu S. SLC34A2 Regulates the Proliferation, Migration, and Invasion of Human Osteosarcoma Cells Through PTEN/PI3K/AKT Signaling. DNA Cell Biol. 2017;36:775-780 pubmed publisher
  15. Wang K, Liu W, Song Y, Wu X, Zhang Y, Li S, et al. The role of angiopoietin-2 in nucleus pulposus cells during human intervertebral disc degeneration. Lab Invest. 2017;97:971-982 pubmed publisher
  16. Kuo T, Chen T, Lee R, Nguyen N, Broughton A, Zhang D, et al. Pik3r1 Is Required for Glucocorticoid-Induced Perilipin 1 Phosphorylation in Lipid Droplet for Adipocyte Lipolysis. Diabetes. 2017;66:1601-1610 pubmed publisher
  17. Chung C, Chang C, Hsu C, Lin K, Peng H, Huang T. Aggretin Venom Polypeptide as a Novel Anti-angiogenesis Agent by Targeting Integrin alpha2beta1. Sci Rep. 2017;7:43612 pubmed publisher
  18. Cao H, Yu S, Chen D, Jing C, Wang Z, Ma R, et al. Liver X receptor agonist T0901317 reverses resistance of A549 human lung cancer cells to EGFR-TKI treatment. FEBS Open Bio. 2017;7:35-43 pubmed publisher
  19. Karki R, Man S, Malireddi R, Kesavardhana S, Zhu Q, Burton A, et al. NLRC3 is an inhibitory sensor of PI3K-mTOR pathways in cancer. Nature. 2016;540:583-587 pubmed publisher
  20. Jung J, Jung H, Neupane S, Kim K, Kim J, Yamamoto H, et al. Involvement of PI3K and PKA pathways in mouse tongue epithelial differentiation. Acta Histochem. 2017;119:92-98 pubmed publisher
  21. Tanouchi A, Taniuchi K, Furihata M, Naganuma S, Dabanaka K, Kimura M, et al. CCDC88A, a prognostic factor for human pancreatic cancers, promotes the motility and invasiveness of pancreatic cancer cells. J Exp Clin Cancer Res. 2016;35:190 pubmed
  22. Kong Q, Zhang H, Zhao T, Zhang W, Yan M, Dong X, et al. Tangshen formula attenuates hepatic steatosis by inhibiting hepatic lipogenesis and augmenting fatty acid oxidation in db/db mice. Int J Mol Med. 2016;38:1715-1726 pubmed publisher
  23. Chruvattil R, Banerjee S, Nath S, Machhi J, Kharkwal G, Yadav M, et al. Dexamethasone Alters the Appetite Regulation via Induction of Hypothalamic Insulin Resistance in Rat Brain. Mol Neurobiol. 2017;54:7483-7496 pubmed publisher
  24. Sheen M, Marotti J, Allegrezza M, Rutkowski M, Conejo Garcia J, Fiering S. Constitutively activated PI3K accelerates tumor initiation and modifies histopathology of breast cancer. Oncogenesis. 2016;5:e267 pubmed publisher
  25. Shao X, Lai D, Zhang L, Xu H. Induction of Autophagy and Apoptosis via PI3K/AKT/TOR Pathways by Azadirachtin A in Spodoptera litura Cells. Sci Rep. 2016;6:35482 pubmed publisher
  26. Cao R, Meng Z, Liu T, Wang G, Qian G, Cao T, et al. Decreased TRPM7 inhibits activities and induces apoptosis of bladder cancer cells via ERK1/2 pathway. Oncotarget. 2016;7:72941-72960 pubmed publisher
  27. De Los Santos S, García Pérez V, Hernández Reséndiz S, Palma Flores C, González Gutiérrez C, Zazueta C, et al. (-)-Epicatechin induces physiological cardiac growth by activation of the PI3K/Akt pathway in mice. Mol Nutr Food Res. 2017;61: pubmed publisher
  28. Zhang Y, Hu S, Chen Y, Guo M, Wang S. Hepatocyte growth factor inhibits hypoxia/reoxygenation-induced activation of xanthine oxidase in endothelial cells through the JAK2 signaling pathway. Int J Mol Med. 2016;38:1055-62 pubmed publisher
  29. Voisinne G, García Blesa A, Chaoui K, Fiore F, Bergot E, Girard L, et al. Co-recruitment analysis of the CBL and CBLB signalosomes in primary T cells identifies CD5 as a key regulator of TCR-induced ubiquitylation. Mol Syst Biol. 2016;12:876 pubmed publisher
  30. Herring A, Münster Y, Akkaya T, Moghaddam S, Deinsberger K, Meyer J, et al. Kallikrein-8 inhibition attenuates Alzheimer's disease pathology in mice. Alzheimers Dement. 2016;12:1273-1287 pubmed publisher
  31. Shriver M, Marimuthu S, Paul C, Geist J, Seale T, Konstantopoulos K, et al. Giant obscurins regulate the PI3K cascade in breast epithelial cells via direct binding to the PI3K/p85 regulatory subunit. Oncotarget. 2016;7:45414-45428 pubmed publisher
  32. Kobayashi K, Araya J, Minagawa S, Hara H, Saito N, Kadota T, et al. Involvement of PARK2-Mediated Mitophagy in Idiopathic Pulmonary Fibrosis Pathogenesis. J Immunol. 2016;197:504-16 pubmed publisher
  33. Lu J, Ji W, Zhao M, Wang M, Yan W, Chen M, et al. Protamine zinc insulin combined with sodium selenite improves glycometabolism in the diabetic KKAy mice. Sci Rep. 2016;6:26563 pubmed publisher
  34. Wang K, Cao P, Wang H, Tang Z, Wang N, Wang J, et al. Chronic administration of Angelica sinensis polysaccharide effectively improves fatty liver and glucose homeostasis in high-fat diet-fed mice. Sci Rep. 2016;6:26229 pubmed publisher
  35. Huang Y, Lin C, Liao H, Liu C, Chen Y, Chiu W, et al. Cholesterol overload induces apoptosis in SH-SY5Y human neuroblastoma cells through the up regulation of flotillin-2 in the lipid raft and the activation of BDNF/Trkb signaling. Neuroscience. 2016;328:201-9 pubmed publisher
  36. Qiu X, Wei R, Li Y, Zhu Q, Xiong C, Chen Y, et al. NEDL2 regulates enteric nervous system and kidney development in its Nedd8 ligase activity-dependent manner. Oncotarget. 2016;7:31440-53 pubmed publisher
  37. Kumar A, Abbas W, Colin L, Khan K, Bouchat S, Varin A, et al. Tuning of AKT-pathway by Nef and its blockade by protease inhibitors results in limited recovery in latently HIV infected T-cell line. Sci Rep. 2016;6:24090 pubmed publisher
  38. Cornick S, Moreau F, Chadee K. Entamoeba histolytica Cysteine Proteinase 5 Evokes Mucin Exocytosis from Colonic Goblet Cells via αvβ3 Integrin. PLoS Pathog. 2016;12:e1005579 pubmed publisher
  39. Osinalde N, Sánchez Quiles V, Blagoev B, Kratchmarova I. Changes in Gab2 phosphorylation and interaction partners in response to interleukin (IL)-2 stimulation in T-lymphocytes. Sci Rep. 2016;6:23530 pubmed publisher
  40. Huang Y, Chen C, Tang K, Sheen J, Tiao M, Tain Y, et al. Postnatal High-Fat Diet Increases Liver Steatosis and Apoptosis Threatened by Prenatal Dexamethasone through the Oxidative Effect. Int J Mol Sci. 2016;17:369 pubmed publisher
  41. Afsar T, Trembley J, Salomon C, Razak S, Khan M, Ahmed K. Growth inhibition and apoptosis in cancer cells induced by polyphenolic compounds of Acacia hydaspica: Involvement of multiple signal transduction pathways. Sci Rep. 2016;6:23077 pubmed publisher
  42. Winnay J, Solheim M, Dirice E, Sakaguchi M, Noh H, Kang H, et al. PI3-kinase mutation linked to insulin and growth factor resistance in vivo. J Clin Invest. 2016;126:1401-12 pubmed publisher
  43. Li M, Lu G, Hu J, Shen X, Ju J, Gao Y, et al. EVA1A/TMEM166 Regulates Embryonic Neurogenesis by Autophagy. Stem Cell Reports. 2016;6:396-410 pubmed publisher
  44. Hung M, Chen Y, Chu P, Shih C, Yu H, Tai W, et al. Upregulation of the oncoprotein SET determines poor clinical outcomes in hepatocellular carcinoma and shows therapeutic potential. Oncogene. 2016;35:4891-902 pubmed publisher
  45. Adighibe O, Leek R, Fernandez Mercado M, Hu J, Snell C, Gatter K, et al. Why some tumours trigger neovascularisation and others don't: the story thus far. Chin J Cancer. 2016;35:18 pubmed publisher
  46. Lakshmipathi J, Alvarez Perez J, Rosselot C, Casinelli G, Stamateris R, Rausell Palamos F, et al. PKCζ Is Essential for Pancreatic β-Cell Replication During Insulin Resistance by Regulating mTOR and Cyclin-D2. Diabetes. 2016;65:1283-96 pubmed publisher
  47. Chen C, Lee T, Kwok C, Hsu Y, Shih K, Lin Y, et al. Cannabinoid receptor type 1 mediates high-fat diet-induced insulin resistance by increasing forkhead box O1 activity in a mouse model of obesity. Int J Mol Med. 2016;37:743-54 pubmed publisher
  48. Yan L, Liu Y, Xiang J, Wu Q, Xu L, Luo X, et al. PIK3R1 targeting by miR-21 suppresses tumor cell migration and invasion by reducing PI3K/AKT signaling and reversing EMT, and predicts clinical outcome of breast cancer. Int J Oncol. 2016;48:471-84 pubmed publisher
  49. Song G, Li Y, Lin L, Cao Y. Anti-autophagic and anti-apoptotic effects of memantine in a SH-SY5Y cell model of Alzheimer's disease via mammalian target of rapamycin-dependent and -independent pathways. Mol Med Rep. 2015;12:7615-22 pubmed publisher
  50. Salim H, Zong D, Hååg P, Novak M, Mörk B, Lewensohn R, et al. DKK1 is a potential novel mediator of cisplatin-refractoriness in non-small cell lung cancer cell lines. BMC Cancer. 2015;15:628 pubmed publisher
  51. Yang L, Li Y, Bhattacharya A, Zhang Y. Inhibition of ERBB2-overexpressing Tumors by Recombinant Human Prolidase and Its Enzymatically Inactive Mutant. EBioMedicine. 2015;2:396-405 pubmed
  52. Li C, Siragy H. (Pro)renin receptor regulates autophagy and apoptosis in podocytes exposed to high glucose. Am J Physiol Endocrinol Metab. 2015;309:E302-10 pubmed publisher
  53. Carnesecchi J, Malbouyres M, de Mets R, Balland M, Beauchef G, Vié K, et al. Estrogens induce rapid cytoskeleton re-organization in human dermal fibroblasts via the non-classical receptor GPR30. PLoS ONE. 2015;10:e0120672 pubmed publisher
  54. Lin Y, Yang Z, Xu A, Dong P, Huang Y, Liu H, et al. PIK3R1 negatively regulates the epithelial-mesenchymal transition and stem-like phenotype of renal cancer cells through the AKT/GSK3β/CTNNB1 signaling pathway. Sci Rep. 2015;5:8997 pubmed publisher
  55. Ito Y, Hart J, Ueno L, Vogt P. Oncogenic activity of the regulatory subunit p85β of phosphatidylinositol 3-kinase (PI3K). Proc Natl Acad Sci U S A. 2014;111:16826-9 pubmed publisher
  56. Ren W, Duan J, Yin J, Liu G, Cao Z, Xiong X, et al. Dietary L-glutamine supplementation modulates microbial community and activates innate immunity in the mouse intestine. Amino Acids. 2014;46:2403-13 pubmed publisher
  57. Kim K, Lee S, Ryu S, Han D. Efficient isolation and elution of cellular proteins using aptamer-mediated protein precipitation assay. Biochem Biophys Res Commun. 2014;448:114-9 pubmed publisher
  58. Wu J, Akkuratov E, Bai Y, Gaskill C, Askari A, Liu L. Cell signaling associated with Na(+)/K(+)-ATPase: activation of phosphatidylinositide 3-kinase IA/Akt by ouabain is independent of Src. Biochemistry. 2013;52:9059-67 pubmed publisher
  59. Luo J, Xu T, Li C, Ba X, Wang X, Jiang Y, et al. p85-RhoGDI2, a novel complex, is required for PSGL-1-induced ?1 integrin-mediated lymphocyte adhesion to VCAM-1. Int J Biochem Cell Biol. 2013;45:2764-73 pubmed publisher
  60. Sollome J, Thavathiru E, Camenisch T, Vaillancourt R. HER2/HER3 regulates extracellular acidification and cell migration through MTK1 (MEKK4). Cell Signal. 2014;26:70-82 pubmed publisher
  61. Chang C, Chen C, Wu M, Chen Y, Chen C, Sheu S, et al. Active Component of Antrodia cinnamomea Mycelia Targeting Head and Neck Cancer Initiating Cells through Exaggerated Autophagic Cell Death. Evid Based Complement Alternat Med. 2013;2013:946451 pubmed publisher