This is a Validated Antibody Database (VAD) review about rat Pias3, based on 6 published articles (read how Labome selects the articles), using Pias3 antibody in all methods. It is aimed to help Labome visitors find the most suited Pias3 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Pias3 synonym: E3 SUMO-protein ligase PIAS3; E3 SUMO-protein transferase PIAS3; KChAP; potassium channel regulatory protein KChAP; potassium channel-associated protein; protein inhibitor of activated STAT protein 3

Santa Cruz Biotechnology
mouse monoclonal (C-12)
  • western blot; human
Santa Cruz Biotechnology Pias3 antibody (Santa Cruz, sc-46682) was used in western blot on human samples . J Biol Chem (2014) ncbi
Invitrogen
rabbit polyclonal
  • immunohistochemistry - frozen section; mouse; loading ...; fig 1g
  • western blot; mouse; loading ...; fig 1e
In order to investigate the contribution of protein inhibitor of activated STAT3 on atherogenesis, Invitrogen Pias3 antibody (Thermo Fisher Scientific, PA5-20953) was used in immunohistochemistry - frozen section on mouse samples (fig 1g) and in western blot on mouse samples (fig 1e). Sci Rep (2016) ncbi
Cell Signaling Technology
rabbit polyclonal
  • western blot; rat; 1:1000; loading ...; fig s2a
Cell Signaling Technology Pias3 antibody (Cell Signaling, 4164) was used in western blot on rat samples at 1:1000 (fig s2a). Cell Death Differ (2017) ncbi
rabbit polyclonal
  • western blot; human; fig 4
In order to investigate the effect of a microtubule inhibitor, MPT0B098, on STAT3 signaling in oral squamous cell carcinoma, Cell Signaling Technology Pias3 antibody (Cell Signaling, 4164) was used in western blot on human samples (fig 4). PLoS ONE (2016) ncbi
rabbit polyclonal
  • western blot; human; fig 8
Cell Signaling Technology Pias3 antibody (Cell Signaling Tech, 4164) was used in western blot on human samples (fig 8). Oncotarget (2015) ncbi
rabbit polyclonal
  • western blot; human; 1:1000; fig 4
In order to determine the role of DBC1 sumoylation in p53-mediated apoptosis, Cell Signaling Technology Pias3 antibody (Cell Signaling, 4164S) was used in western blot on human samples at 1:1000 (fig 4). Nat Commun (2014) ncbi
Articles Reviewed
  1. Tao C, Hsu W, Ma Y, Cheng S, Lee E. Epigenetic regulation of HDAC1 SUMOylation as an endogenous neuroprotection against Aβ toxicity in a mouse model of Alzheimer's disease. Cell Death Differ. 2017;24:597-614 pubmed publisher
  2. Wang R, Zhang Y, Xu L, Lin Y, Yang X, Bai L, et al. Protein Inhibitor of Activated STAT3 Suppresses Oxidized LDL-induced Cell Responses during Atherosclerosis in Apolipoprotein E-deficient Mice. Sci Rep. 2016;6:36790 pubmed publisher
  3. Peng H, Cheng Y, Hsu Y, Wu G, Kuo C, Liou J, et al. MPT0B098, a Microtubule Inhibitor, Suppresses JAK2/STAT3 Signaling Pathway through Modulation of SOCS3 Stability in Oral Squamous Cell Carcinoma. PLoS ONE. 2016;11:e0158440 pubmed publisher
  4. Pitari M, Rossi M, Amodio N, Botta C, Morelli E, Federico C, et al. Inhibition of miR-21 restores RANKL/OPG ratio in multiple myeloma-derived bone marrow stromal cells and impairs the resorbing activity of mature osteoclasts. Oncotarget. 2015;6:27343-58 pubmed publisher
  5. Park J, Lee S, Yang S, Yoo H, Park J, Seong M, et al. Modification of DBC1 by SUMO2/3 is crucial for p53-mediated apoptosis in response to DNA damage. Nat Commun. 2014;5:5483 pubmed publisher
  6. Wang W, Chen Y, Wang S, Hu N, Cao Z, Wang W, et al. PIASx? ligase enhances SUMO1 modification of PTEN protein as a SUMO E3 ligase. J Biol Chem. 2014;289:3217-30 pubmed publisher