This is a Validated Antibody Database (VAD) review about rat Pdha1l1, based on 18 published articles (read how Labome selects the articles), using Pdha1l1 antibody in all methods. It is aimed to help Labome visitors find the most suited Pdha1l1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Pdha1l1 synonym: pyruvate dehydrogenase E1 alpha 1 pseudogene

Knockout validation
Cell Signaling Technology
rabbit monoclonal (C54G1)
  • western blot knockout validation; human; loading ...; fig 2c
  • immunohistochemistry - paraffin section; human; loading ...; fig 6a
Cell Signaling Technology Pdha1l1 antibody (Cell signaling, C54G1) was used in western blot knockout validation on human samples (fig 2c) and in immunohistochemistry - paraffin section on human samples (fig 6a). Oncotarget (2017) ncbi
Cell Signaling Technology
rabbit monoclonal (C54G1)
  • western blot knockout validation; human; loading ...; fig 3a
Cell Signaling Technology Pdha1l1 antibody (Cell Signaling Technology, C54G1) was used in western blot knockout validation on human samples (fig 3a). Oncotarget (2016) ncbi
Cell Signaling Technology
rabbit monoclonal (C54G1)
  • western blot; human; loading ...; fig 3f
Cell Signaling Technology Pdha1l1 antibody (Cell Signaling, 3205) was used in western blot on human samples (fig 3f). Cell (2019) ncbi
rabbit monoclonal (C54G1)
  • western blot; human; fig 5f
Cell Signaling Technology Pdha1l1 antibody (Cell Signaling, 3205) was used in western blot on human samples (fig 5f). Sci Rep (2017) ncbi
rabbit monoclonal (C54G1)
  • western blot; human; loading ...; fig 5e
Cell Signaling Technology Pdha1l1 antibody (Cell Signaling, 3205) was used in western blot on human samples (fig 5e). Sci Rep (2017) ncbi
rabbit monoclonal (C54G1)
  • western blot knockout validation; human; loading ...; fig 2c
  • immunohistochemistry - paraffin section; human; loading ...; fig 6a
Cell Signaling Technology Pdha1l1 antibody (Cell signaling, C54G1) was used in western blot knockout validation on human samples (fig 2c) and in immunohistochemistry - paraffin section on human samples (fig 6a). Oncotarget (2017) ncbi
rabbit monoclonal (C54G1)
  • western blot; human; fig 7
In order to describe the effects of long- and short-term exposure to erythropoietin on white adipose tissue, Cell Signaling Technology Pdha1l1 antibody (Cell signaling, 3205) was used in western blot on human samples (fig 7). Lipids Health Dis (2016) ncbi
rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig 5a
In order to research the role of ORP4L for T-cell acute lymphoblastic leukemia cell survival, Cell Signaling Technology Pdha1l1 antibody (cell signalling, 2784) was used in western blot on human samples at 1:1000 (fig 5a). Nat Commun (2016) ncbi
rabbit monoclonal (C54G1)
  • western blot; mouse; loading ...; fig 3g
In order to test if LKB1 mutations contribute to cervical cancer initiation and progress, Cell Signaling Technology Pdha1l1 antibody (Cell signaling, 3205) was used in western blot on mouse samples (fig 3g). Oncogene (2017) ncbi
rabbit monoclonal (C54G1)
  • western blot knockout validation; human; loading ...; fig 3a
Cell Signaling Technology Pdha1l1 antibody (Cell Signaling Technology, C54G1) was used in western blot knockout validation on human samples (fig 3a). Oncotarget (2016) ncbi
rabbit monoclonal (C54G1)
  • western blot; human; fig 3
Cell Signaling Technology Pdha1l1 antibody (Cell Signaling, C54G1) was used in western blot on human samples (fig 3). Sci Rep (2016) ncbi
rabbit monoclonal (C54G1)
  • western blot; human; 1:1000; loading ...; tbl 1
In order to examine the effect of ghrelin in human Sertoli cells metabolism, Cell Signaling Technology Pdha1l1 antibody (Cell Signaling, 3205) was used in western blot on human samples at 1:1000 (tbl 1). Mol Cell Endocrinol (2016) ncbi
rabbit monoclonal (C54G1)
  • western blot; mouse; 1:1000; loading ...; fig 1c
In order to develop a method to assess mitochondrial pyruvate carrier activity, Cell Signaling Technology Pdha1l1 antibody (Cell Signaling, 3205S) was used in western blot on mouse samples at 1:1000 (fig 1c). J Biol Chem (2016) ncbi
rabbit monoclonal (C54G1)
  • western blot; rat; 1:1000; fig 8
In order to investigate thyroid hormone-mediated autophagy in skeletal muscle, Cell Signaling Technology Pdha1l1 antibody (Cell Signaling Technology, 3205) was used in western blot on rat samples at 1:1000 (fig 8). Endocrinology (2016) ncbi
rabbit polyclonal
  • western blot; mouse; fig 3
Cell Signaling Technology Pdha1l1 antibody (Cell Signaling, 2784) was used in western blot on mouse samples (fig 3). PLoS ONE (2015) ncbi
rabbit monoclonal (C54G1)
  • western blot; human; 1:1000; loading ...; fig 4b
Cell Signaling Technology Pdha1l1 antibody (Cell Signaling, 3205) was used in western blot on human samples at 1:1000 (fig 4b). Oncotarget (2015) ncbi
rabbit polyclonal
  • western blot; pig; fig 10
Cell Signaling Technology Pdha1l1 antibody (Cell signaling, 2784S) was used in western blot on pig samples (fig 10). Am J Physiol Heart Circ Physiol (2015) ncbi
rabbit monoclonal (C54G1)
  • western blot; rat; 1:10000
In order to investigate the role of mitochondria-associated miRNAs in traumatic brain injury, Cell Signaling Technology Pdha1l1 antibody (Cell Signaling, 3205) was used in western blot on rat samples at 1:10000. Exp Neurol (2015) ncbi
rabbit polyclonal
  • immunohistochemistry - free floating section; mouse; 1:200
In order to use Nfix(-/-) mice to study development of the nervous system, Cell Signaling Technology Pdha1l1 antibody (Cell Signaling Technology, 2784) was used in immunohistochemistry - free floating section on mouse samples at 1:200. Cereb Cortex (2015) ncbi
rabbit monoclonal (C54G1)
  • western blot; mouse; fig 2
Cell Signaling Technology Pdha1l1 antibody (Cell Signaling Tech, 3205) was used in western blot on mouse samples (fig 2). Autophagy (2014) ncbi
Articles Reviewed
  1. Zhang W, Wang G, Xu Z, Tu H, Hu F, Dai J, et al. Lactate Is a Natural Suppressor of RLR Signaling by Targeting MAVS. Cell. 2019;: pubmed publisher
  2. Zhao X, Sun K, Lan Z, Song W, Cheng L, Chi W, et al. Tenofovir and adefovir down-regulate mitochondrial chaperone TRAP1 and succinate dehydrogenase subunit B to metabolically reprogram glucose metabolism and induce nephrotoxicity. Sci Rep. 2017;7:46344 pubmed publisher
  3. Møller A, Kampmann U, Hedegaard J, Thorsen K, Nordentoft I, Vendelbo M, et al. Altered gene expression and repressed markers of autophagy in skeletal muscle of insulin resistant patients with type 2 diabetes. Sci Rep. 2017;7:43775 pubmed publisher
  4. Zhong Y, Li X, Ji Y, Li X, Li Y, Yu D, et al. Pyruvate dehydrogenase expression is negatively associated with cell stemness and worse clinical outcome in prostate cancers. Oncotarget. 2017;8:13344-13356 pubmed publisher
  5. Christensen B, Nellemann B, Jørgensen J, Pedersen S, Jessen N. Erythropoietin does not activate erythropoietin receptor signaling or lipolytic pathways in human subcutaneous white adipose tissue in vivo. Lipids Health Dis. 2016;15:160 pubmed publisher
  6. Zhong W, Yi Q, Xu B, Li S, Wang T, Liu F, et al. ORP4L is essential for T-cell acute lymphoblastic leukemia cell survival. Nat Commun. 2016;7:12702 pubmed publisher
  7. Zeng Q, Chen J, Li Y, Werle K, Zhao R, Quan C, et al. LKB1 inhibits HPV-associated cancer progression by targeting cellular metabolism. Oncogene. 2017;36:1245-1255 pubmed publisher
  8. Li Y, Li X, Li X, Zhong Y, Ji Y, Yu D, et al. PDHA1 gene knockout in prostate cancer cells results in metabolic reprogramming towards greater glutamine dependence. Oncotarget. 2016;7:53837-53852 pubmed publisher
  9. Ma T, Fan B, Zhang C, Zhao H, Han C, Gao C, et al. Metabonomics applied in exploring the antitumour mechanism of physapubenolide on hepatocellular carcinoma cells by targeting glycolysis through the Akt-p53 pathway. Sci Rep. 2016;6:29926 pubmed publisher
  10. Martins A, Sá R, Monteiro M, Barros A, Sousa M, Carvalho R, et al. Ghrelin acts as energy status sensor of male reproduction by modulating Sertoli cells glycolytic metabolism and mitochondrial bioenergetics. Mol Cell Endocrinol. 2016;434:199-209 pubmed publisher
  11. Gray L, Rauckhorst A, Taylor E. A Method for Multiplexed Measurement of Mitochondrial Pyruvate Carrier Activity. J Biol Chem. 2016;291:7409-17 pubmed publisher
  12. Lesmana R, Sinha R, Singh B, Zhou J, Ohba K, Wu Y, et al. Thyroid Hormone Stimulation of Autophagy Is Essential for Mitochondrial Biogenesis and Activity in Skeletal Muscle. Endocrinology. 2016;157:23-38 pubmed publisher
  13. Ledee D, Smith L, Bruce M, Kajimoto M, Isern N, Portman M, et al. c-Myc Alters Substrate Utilization and O-GlcNAc Protein Posttranslational Modifications without Altering Cardiac Function during Early Aortic Constriction. PLoS ONE. 2015;10:e0135262 pubmed publisher
  14. Loureiro R, Magalhães Novais S, Mesquita K, Baldeiras I, Sousa I, Tavares L, et al. Melatonin antiproliferative effects require active mitochondrial function in embryonal carcinoma cells. Oncotarget. 2015;6:17081-96 pubmed
  15. Ledee D, Kajimoto M, O Kelly Priddy C, Olson A, Isern N, Robillard Frayne I, et al. Pyruvate modifies metabolic flux and nutrient sensing during extracorporeal membrane oxygenation in an immature swine model. Am J Physiol Heart Circ Physiol. 2015;309:H137-46 pubmed publisher
  16. Wang W, Visavadiya N, Pandya J, Nelson P, Sullivan P, Springer J. Mitochondria-associated microRNAs in rat hippocampus following traumatic brain injury. Exp Neurol. 2015;265:84-93 pubmed publisher
  17. Heng Y, Zhou B, Harris L, Harvey T, Smith A, Horne E, et al. NFIX Regulates Proliferation and Migration Within the Murine SVZ Neurogenic Niche. Cereb Cortex. 2015;25:3758-78 pubmed publisher
  18. Furuya N, Ikeda S, Sato S, Soma S, Ezaki J, Oliva Trejo J, et al. PARK2/Parkin-mediated mitochondrial clearance contributes to proteasome activation during slow-twitch muscle atrophy via NFE2L1 nuclear translocation. Autophagy. 2014;10:631-41 pubmed publisher