This is a Validated Antibody Database (VAD) review about rat Park7, based on 16 published articles (read how Labome selects the articles), using Park7 antibody in all methods. It is aimed to help Labome visitors find the most suited Park7 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Park7 synonym: CAP1; DJ-1; Dj1; SP22

Knockout validation
Cell Signaling Technology
domestic rabbit monoclonal (D29E5)
  • western blot knockout validation; pigs ; 1:1000; fig 6
Cell Signaling Technology Park7 antibody (Cell Signaling, 5933) was used in western blot knockout validation on pigs samples at 1:1000 (fig 6). Sci Rep (2014) ncbi
Abcam
domestic rabbit monoclonal (EP2815Y)
  • western blot; rat; 1:1000; loading ...; fig 2a
Abcam Park7 antibody (Abcam, ab76008) was used in western blot on rat samples at 1:1000 (fig 2a). J Neuroinflammation (2020) ncbi
domestic rabbit monoclonal
  • western blot; human; loading ...; fig 4e
Abcam Park7 antibody (Abcam, ab76241) was used in western blot on human samples (fig 4e). Cell (2019) ncbi
domestic rabbit monoclonal (EP2815Y)
  • other; human; loading ...; fig 4c
Abcam Park7 antibody (Abcam, ab76008) was used in other on human samples (fig 4c). Cancer Cell (2018) ncbi
domestic rabbit polyclonal
  • western blot; rat; ; loading ...; fig 5a
Abcam Park7 antibody (Abcam, ab18257) was used in western blot on rat samples at (fig 5a). PLoS ONE (2018) ncbi
domestic rabbit monoclonal (EP2815Y)
  • western blot; human; loading ...; fig 1g
Abcam Park7 antibody (Abcam, ab76008) was used in western blot on human samples (fig 1g). Cell Syst (2017) ncbi
domestic rabbit monoclonal (EP2815Y)
  • reverse phase protein lysate microarray; human; loading ...; fig st6
In order to characterize the molecular identity of uterine carcinosarcomas., Abcam Park7 antibody (Abcam, ab76008) was used in reverse phase protein lysate microarray on human samples (fig st6). Cancer Cell (2017) ncbi
domestic rabbit monoclonal (EP2815Y)
  • reverse phase protein lysate microarray; human; loading ...; fig 3a
In order to describe the features of 228 primary cervical cancers, Abcam Park7 antibody (Abcam, ab76008) was used in reverse phase protein lysate microarray on human samples (fig 3a). Nature (2017) ncbi
domestic rabbit polyclonal
  • immunohistochemistry; pigs ; 1:20,000; loading ...; tbl 1
In order to analyze oxidative stress markers after remote ischemic preconditioning in pig., Abcam Park7 antibody (Abcam, ab 18257) was used in immunohistochemistry on pigs samples at 1:20,000 (tbl 1). Semin Thorac Cardiovasc Surg (2016) ncbi
domestic rabbit monoclonal (EP2815Y)
  • immunocytochemistry; human; 1:50; loading ...; fig 3
Abcam Park7 antibody (abcam, ab76008) was used in immunocytochemistry on human samples at 1:50 (fig 3). J Biol Chem (2015) ncbi
domestic rabbit monoclonal (EP2815Y)
  • western blot; mouse; 1:15000
Abcam Park7 antibody (AbCam, ab76008) was used in western blot on mouse samples at 1:15000. Free Radic Biol Med (2014) ncbi
domestic rabbit monoclonal (EP2815Y)
  • immunocytochemistry; human
Abcam Park7 antibody (Abcam, ab76008) was used in immunocytochemistry on human samples . J Proteome Res (2014) ncbi
Santa Cruz Biotechnology
mouse monoclonal (A-9)
  • western blot; mouse; loading ...; fig 2a, 2b
Santa Cruz Biotechnology Park7 antibody (Santa Cruz, sc-55573) was used in western blot on mouse samples (fig 2a, 2b). Cell Death Dis (2021) ncbi
mouse monoclonal (D-4)
  • immunohistochemistry - paraffin section; human; loading ...; fig 5d
  • western blot; human; 1:1000; loading ...; fig 1b
Santa Cruz Biotechnology Park7 antibody (Santa Cruz Biotechnology, sc-55572) was used in immunohistochemistry - paraffin section on human samples (fig 5d) and in western blot on human samples at 1:1000 (fig 1b). Oncol Rep (2020) ncbi
Invitrogen
domestic rabbit polyclonal
  • western blot; human; 1:1000; fig 4a
In order to use a fruit fly model to identify compounds that alleviate Parkinson's disease, Invitrogen Park7 antibody (Thermo Fisher Scientific, PA1-32440) was used in western blot on human samples at 1:1000 (fig 4a). Free Radic Biol Med (2017) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (D29E5)
  • immunohistochemistry; human; loading ...; fig 1
Cell Signaling Technology Park7 antibody (cell signalling, 5933) was used in immunohistochemistry on human samples (fig 1). Oxid Med Cell Longev (2017) ncbi
domestic rabbit monoclonal (D29E5)
  • western blot knockout validation; pigs ; 1:1000; fig 6
Cell Signaling Technology Park7 antibody (Cell Signaling, 5933) was used in western blot knockout validation on pigs samples at 1:1000 (fig 6). Sci Rep (2014) ncbi
Articles Reviewed
  1. Lin Z, Chen C, Yang D, Ding J, Wang G, Ren H. DJ-1 inhibits microglial activation and protects dopaminergic neurons in vitro and in vivo through interacting with microglial p65. Cell Death Dis. 2021;12:715 pubmed publisher
  2. Wang W, Wang H, Xiang L, Ni T, Jin F, Deng J, et al. DJ‑1 is a new prognostic marker and predicts chemotherapy efficacy in colorectal cancer. Oncol Rep. 2020;44:77-90 pubmed publisher
  3. Peng L, Zhou Y, Jiang N, Wang T, Zhu J, Chen Y, et al. DJ-1 exerts anti-inflammatory effects and regulates NLRX1-TRAF6 via SHP-1 in stroke. J Neuroinflammation. 2020;17:81 pubmed publisher
  4. Jeppesen D, Fenix A, Franklin J, Higginbotham J, Zhang Q, Zimmerman L, et al. Reassessment of Exosome Composition. Cell. 2019;177:428-445.e18 pubmed publisher
  5. Ng P, Li J, Jeong K, Shao S, Chen H, Tsang Y, et al. Systematic Functional Annotation of Somatic Mutations in Cancer. Cancer Cell. 2018;33:450-462.e10 pubmed publisher
  6. Gravesen E, Lerche Mace M, Nordholm A, Hofman Bang J, Hruska K, Haagen Nielsen C, et al. Exogenous BMP7 in aortae of rats with chronic uremia ameliorates expression of profibrotic genes, but does not reverse established vascular calcification. PLoS ONE. 2018;13:e0190820 pubmed publisher
  7. Malty R, Aoki H, Kumar A, Phanse S, Amin S, Zhang Q, et al. A Map of Human Mitochondrial Protein Interactions Linked to Neurodegeneration Reveals New Mechanisms of Redox Homeostasis and NF-κB Signaling. Cell Syst. 2017;5:564-577.e12 pubmed publisher
  8. Sanz F, Solana Manrique C, Muñoz Soriano V, Calap Quintana P, Moltó M, Paricio N. Identification of potential therapeutic compounds for Parkinson's disease using Drosophila and human cell models. Free Radic Biol Med. 2017;108:683-691 pubmed publisher
  9. Qin L, Tan J, Zhang H, Rizwana K, Lu J, Tang J, et al. BAG5 Interacts with DJ-1 and Inhibits the Neuroprotective Effects of DJ-1 to Combat Mitochondrial Oxidative Damage. Oxid Med Cell Longev. 2017;2017:5094934 pubmed publisher
  10. Cherniack A, Shen H, Walter V, Stewart C, Murray B, Bowlby R, et al. Integrated Molecular Characterization of Uterine Carcinosarcoma. Cancer Cell. 2017;31:411-423 pubmed publisher
  11. . Integrated genomic and molecular characterization of cervical cancer. Nature. 2017;543:378-384 pubmed publisher
  12. Arvola O, Haapanen H, Herajärvi J, Anttila T, Puistola U, Karihtala P, et al. Remote Ischemic Preconditioning Reduces Cerebral Oxidative Stress Following Hypothermic Circulatory Arrest in a Porcine Model. Semin Thorac Cardiovasc Surg. 2016;28:92-102 pubmed publisher
  13. Takahashi Niki K, Kato Ose I, Murata H, Maita H, Iguchi Ariga S, Ariga H. Epidermal Growth Factor-dependent Activation of the Extracellular Signal-regulated Kinase Pathway by DJ-1 Protein through Its Direct Binding to c-Raf Protein. J Biol Chem. 2015;290:17838-47 pubmed publisher
  14. Yao J, Huang J, Hai T, Wang X, Qin G, Zhang H, et al. Efficient bi-allelic gene knockout and site-specific knock-in mediated by TALENs in pigs. Sci Rep. 2014;4:6926 pubmed publisher
  15. Tanti G, Goswami S. SG2NA recruits DJ-1 and Akt into the mitochondria and membrane to protect cells from oxidative damage. Free Radic Biol Med. 2014;75:1-13 pubmed publisher
  16. Pinto G, Alhaiek A, Amadi S, Qattan A, Crawford M, Radulovic M, et al. Systematic nucleo-cytoplasmic trafficking of proteins following exposure of MCF7 breast cancer cells to estradiol. J Proteome Res. 2014;13:1112-27 pubmed publisher