This is a Validated Antibody Database (VAD) review about rat Pak4, based on 8 published articles (read how Labome selects the articles), using Pak4 antibody in all methods. It is aimed to help Labome visitors find the most suited Pak4 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Pak4 synonym: serine/threonine-protein kinase PAK 4; p21 (CDKN1A)-activated kinase 4; p21 protein (Cdc42/Rac)-activated kinase 4; p21-activated kinase 4

Abcam
rabbit monoclonal (EPR2471(2))
  • western blot; mouse; fig 7e
Abcam Pak4 antibody (Abcam, EPR2471(2)) was used in western blot on mouse samples (fig 7e). Haematologica (2017) ncbi
Santa Cruz Biotechnology
mouse monoclonal (B-6)
  • immunohistochemistry - frozen section; human; fig 2
  • western blot; human; fig 1
Santa Cruz Biotechnology Pak4 antibody (Santa Cruz, sc-393367) was used in immunohistochemistry - frozen section on human samples (fig 2) and in western blot on human samples (fig 1). PLoS ONE (2016) ncbi
Cell Signaling Technology
rabbit polyclonal
  • other; human; loading ...; fig 4c
Cell Signaling Technology Pak4 antibody (Cell Signaling, 3242) was used in other on human samples (fig 4c). Cancer Cell (2018) ncbi
rabbit polyclonal
  • immunoprecipitation; mouse; loading ...; fig 1
  • western blot; mouse; 1:1000; loading ...; fig 1
Cell Signaling Technology Pak4 antibody (Cell Signaling, 3242) was used in immunoprecipitation on mouse samples (fig 1) and in western blot on mouse samples at 1:1000 (fig 1). Nat Commun (2015) ncbi
rabbit polyclonal
  • western blot; human; fig 4
In order to study the molecular mechanisms underlying malignant changes of meningioma cells, Cell Signaling Technology Pak4 antibody (Cell Signaling Technology, 3242) was used in western blot on human samples (fig 4). Oncotarget (2015) ncbi
rabbit polyclonal
  • western blot; human; fig 2
Cell Signaling Technology Pak4 antibody (Cell Signaling Technology, 3242) was used in western blot on human samples (fig 2). Cardiovasc Res (2015) ncbi
rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig 2a
Cell Signaling Technology Pak4 antibody (cell signalling, 3242) was used in western blot on human samples at 1:1000 (fig 2a). Carcinogenesis (2014) ncbi
Sigma-Aldrich
rabbit polyclonal
  • western blot; human; 1:2000; loading ...; fig 5a
Sigma-Aldrich Pak4 antibody (Sigma, SAB4504052) was used in western blot on human samples at 1:2000 (fig 5a). J Neurochem (2015) ncbi
Articles Reviewed
  1. Ng P, Li J, Jeong K, Shao S, Chen H, Tsang Y, et al. Systematic Functional Annotation of Somatic Mutations in Cancer. Cancer Cell. 2018;33:450-462.e10 pubmed publisher
  2. Beauchemin H, Shooshtarizadeh P, Vadnais C, Vassen L, Pastore Y, Moroy T. Gfi1b controls integrin signaling-dependent cytoskeleton dynamics and organization in megakaryocytes. Haematologica. 2017;102:484-497 pubmed publisher
  3. Wang Y, Gratzke C, Tamalunas A, Wiemer N, Ciotkowska A, Rutz B, et al. P21-Activated Kinase Inhibitors FRAX486 and IPA3: Inhibition of Prostate Stromal Cell Growth and Effects on Smooth Muscle Contraction in the Human Prostate. PLoS ONE. 2016;11:e0153312 pubmed publisher
  4. Civiero L, Cirnaru M, Beilina A, Rodella U, Russo I, Belluzzi E, et al. Leucine-rich repeat kinase 2 interacts with p21-activated kinase 6 to control neurite complexity in mammalian brain. J Neurochem. 2015;135:1242-56 pubmed publisher
  5. Singh N, Kotla S, Dyukova E, Traylor J, Orr A, Chernoff J, et al. Disruption of p21-activated kinase 1 gene diminishes atherosclerosis in apolipoprotein E-deficient mice. Nat Commun. 2015;6:7450 pubmed publisher
  6. Chow H, Dong B, Duron S, Campbell D, Ong C, Hoeflich K, et al. Group I Paks as therapeutic targets in NF2-deficient meningioma. Oncotarget. 2015;6:1981-94 pubmed
  7. Komaravolu R, Adam C, Moonen J, Harmsen M, Goebeler M, Schmidt M. Erk5 inhibits endothelial migration via KLF2-dependent down-regulation of PAK1. Cardiovasc Res. 2015;105:86-95 pubmed publisher
  8. Kim T, Kang Y, Park Z, Kim Y, Hong S, Oh S, et al. SH3RF2 functions as an oncogene by mediating PAK4 protein stability. Carcinogenesis. 2014;35:624-34 pubmed publisher