This is a Validated Antibody Database (VAD) review about rat P2ry12, based on 7 published articles (read how Labome selects the articles), using P2ry12 antibody in all methods. It is aimed to help Labome visitors find the most suited P2ry12 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
P2ry12 synonym: P2y12; P2Y purinoceptor 12; P2Y12 platelet ADP receptor; purinergic receptor P2Y, G-protein coupled, 12

Abcam
rabbit monoclonal (EPR18611)
  • immunohistochemistry - frozen section; rat; 1:150; loading ...; fig 2
Abcam P2ry12 antibody (Abcam, ab184411) was used in immunohistochemistry - frozen section on rat samples at 1:150 (fig 2). Cell Physiol Biochem (2018) ncbi
rabbit monoclonal (EPR18611)
  • western blot; human; loading ...; fig s4
Abcam P2ry12 antibody (Abcam, EPR18611) was used in western blot on human samples (fig s4). Cancers (Basel) (2017) ncbi
rabbit monoclonal (EPR18611)
  • western blot; rat; 1:1000; fig 2c
Abcam P2ry12 antibody (Abcam, ab184411) was used in western blot on rat samples at 1:1000 (fig 2c). J Neuroinflammation (2017) ncbi
Alomone Labs
rabbit polyclonal
  • immunocytochemistry; human; 1:100; fig 1b
Alomone Labs P2ry12 antibody (Alomone Labs, APR-020) was used in immunocytochemistry on human samples at 1:100 (fig 1b). Mol Psychiatry (2017) ncbi
rabbit polyclonal
  • immunohistochemistry - paraffin section; human; loading ...; tbl 1
In order to study P2Y12 expression in human brain tissue, Alomone Labs P2ry12 antibody (Alomone, APR-020) was used in immunohistochemistry - paraffin section on human samples (tbl 1). Glia (2017) ncbi
Invitrogen
rabbit polyclonal
  • immunohistochemistry; mouse; 1:100; loading ...; fig 3s1d
Invitrogen P2ry12 antibody (ThermoFisher, PA5-77671) was used in immunohistochemistry on mouse samples at 1:100 (fig 3s1d). elife (2019) ncbi
Sigma-Aldrich
rabbit polyclonal
  • immunohistochemistry - free floating section; rat; 1:100; fig 4a
In order to test if the microglial P2Y12 receptor in the trigeminal spinal subnucleus caudalis is involved in intraoral cancer pain, Sigma-Aldrich P2ry12 antibody (Sigma, P4871) was used in immunohistochemistry - free floating section on rat samples at 1:100 (fig 4a). J Dent Res (2016) ncbi
Articles Reviewed
  1. Ma W, Silverman S, Zhao L, Villasmil R, Campos M, Amaral J, et al. Absence of TGFβ signaling in retinal microglia induces retinal degeneration and exacerbates choroidal neovascularization. elife. 2019;8: pubmed publisher
  2. Sheng X, Wang J, Guo J, Xu Y, Jiang H, Zheng C, et al. Effects of Baicalin on Diabetic Cardiac Autonomic Neuropathy Mediated by the P2Y12 Receptor in Rat Stellate Ganglia. Cell Physiol Biochem. 2018;46:986-998 pubmed publisher
  3. Elaskalani O, Falasca M, Moran N, Berndt M, Metharom P. The Role of Platelet-Derived ADP and ATP in Promoting Pancreatic Cancer Cell Survival and Gemcitabine Resistance. Cancers (Basel). 2017;9: pubmed publisher
  4. Niu J, Huang D, Zhou R, Yue M, Xu T, Yang J, et al. Activation of dorsal horn cannabinoid CB2 receptor suppresses the expression of P2Y12 and P2Y13 receptors in neuropathic pain rats. J Neuroinflammation. 2017;14:185 pubmed publisher
  5. Sellgren C, Sheridan S, Gracias J, Xuan D, Fu T, Perlis R. Patient-specific models of microglia-mediated engulfment of synapses and neural progenitors. Mol Psychiatry. 2017;22:170-177 pubmed publisher
  6. Mildner A, Huang H, Radke J, Stenzel W, Priller J. P2Y12 receptor is expressed on human microglia under physiological conditions throughout development and is sensitive to neuroinflammatory diseases. Glia. 2017;65:375-387 pubmed publisher
  7. Tamagawa T, Shinoda M, Honda K, Furukawa A, Kaji K, Nagashima H, et al. Involvement of Microglial P2Y12 Signaling in Tongue Cancer Pain. J Dent Res. 2016;95:1176-82 pubmed publisher