This is a Validated Antibody Database (VAD) review about rat P2rx7, based on 9 published articles (read how Labome selects the articles), using P2rx7 antibody in all methods. It is aimed to help Labome visitors find the most suited P2rx7 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
P2rx7 synonym: P2X purinoceptor 7; ATP receptor; P2X7 purinoceptor; P2Z receptor; purinergic receptor P2X, ligand-gated ion channel, 7; purinergic receptor P2X7

Knockout validation
Alomone Labs
rabbit polyclonal
  • western blot knockout validation; mouse; loading ...; fig s2b
In order to characterize the P2X7R-secretome in M1 and M2 macrophages., Alomone Labs P2rx7 antibody (Alomone, APR-004) was used in western blot knockout validation on mouse samples (fig s2b). Sci Rep (2016) ncbi
Alomone Labs
rabbit polyclonal
  • immunohistochemistry - frozen section; mouse; 1:200; loading ...; fig 5a
  • western blot; mouse; 1:200; loading ...; fig 5a
Alomone Labs P2rx7 antibody (Alomone, APR-004) was used in immunohistochemistry - frozen section on mouse samples at 1:200 (fig 5a) and in western blot on mouse samples at 1:200 (fig 5a). Chin Med J (Engl) (2018) ncbi
rabbit polyclonal
  • western blot; mouse; 1:500; loading ...; fig 3a
In order to elucidate the role of P2X7 in alveolar epithelial cells, Alomone Labs P2rx7 antibody (alomone labs, APR-004) was used in western blot on mouse samples at 1:500 (fig 3a). Histochem Cell Biol (2016) ncbi
rabbit polyclonal
  • immunohistochemistry - paraffin section; human; 1:200; fig 4c
  • western blot; human; 1:500; fig 2f
In order to examine the contribution of the ATP-gated receptor P2X7 to pancreatic ductal adenocarcinoma, Alomone Labs P2rx7 antibody (Alomone, APR-004) was used in immunohistochemistry - paraffin section on human samples at 1:200 (fig 4c) and in western blot on human samples at 1:500 (fig 2f). Int J Cancer (2016) ncbi
rabbit polyclonal
  • western blot knockout validation; mouse; loading ...; fig s2b
In order to characterize the P2X7R-secretome in M1 and M2 macrophages., Alomone Labs P2rx7 antibody (Alomone, APR-004) was used in western blot knockout validation on mouse samples (fig s2b). Sci Rep (2016) ncbi
rabbit polyclonal
  • western blot; mouse; fig 2
Alomone Labs P2rx7 antibody (Alomone Labs, APR 004) was used in western blot on mouse samples (fig 2). Nat Commun (2016) ncbi
rabbit polyclonal
  • immunocytochemistry; mouse; 1:200; fig 1
  • western blot; mouse; 1:1000; fig 1
Alomone Labs P2rx7 antibody (Alomone Laboratories, PR-004) was used in immunocytochemistry on mouse samples at 1:200 (fig 1) and in western blot on mouse samples at 1:1000 (fig 1). Sci Rep (2015) ncbi
rabbit polyclonal
  • immunohistochemistry; mouse; 1:200; loading ...; fig 2c
  • western blot; mouse; 1:200; loading ...; fig 2b
Alomone Labs P2rx7 antibody (Alomone labs, APR-004) was used in immunohistochemistry on mouse samples at 1:200 (fig 2c) and in western blot on mouse samples at 1:200 (fig 2b). Sci Rep (2015) ncbi
rabbit polyclonal
  • immunohistochemistry - frozen section; mouse; 1:250-1:1000
  • western blot; mouse; 1:500-1:1000
Alomone Labs P2rx7 antibody (Alomone, APR-004) was used in immunohistochemistry - frozen section on mouse samples at 1:250-1:1000 and in western blot on mouse samples at 1:500-1:1000. J Neurosci Res (2014) ncbi
Invitrogen
rabbit polyclonal
  • immunohistochemistry - paraffin section; human; 1:900; fig 4d
In order to examine the contribution of the ATP-gated receptor P2X7 to pancreatic ductal adenocarcinoma, Invitrogen P2rx7 antibody (Life Technologies, PA5-28020) was used in immunohistochemistry - paraffin section on human samples at 1:900 (fig 4d). Int J Cancer (2016) ncbi
Sigma-Aldrich
rabbit polyclonal
  • immunoprecipitation; human; 1:200; loading ...; fig s1a
  • immunocytochemistry; human; 1:50; loading ...; fig s2g
  • western blot; human; 1:200; loading ...; fig s1a
Sigma-Aldrich P2rx7 antibody (Sigma-Aldrich, P8232) was used in immunoprecipitation on human samples at 1:200 (fig s1a), in immunocytochemistry on human samples at 1:50 (fig s2g) and in western blot on human samples at 1:200 (fig s1a). J Clin Invest (2018) ncbi
Articles Reviewed
  1. Hou X, Dong H, Sun L, Yang M, Cheng H, Chen Y. Purinergic 2X7 Receptor is Involved in the Podocyte Damage of Obesity-Related Glomerulopathy via Activating Nucleotide-Binding and Oligomerization Domain-Like Receptor Protein 3 Inflammasome. Chin Med J (Engl). 2018;131:2713-2725 pubmed publisher
  2. D Addio F, Vergani A, Potena L, Maestroni A, Usuelli V, Ben Nasr M, et al. P2X7R mutation disrupts the NLRP3-mediated Th program and predicts poor cardiac allograft outcomes. J Clin Invest. 2018;128:3490-3503 pubmed publisher
  3. Barth K, Blasche R, Neiser A, Bramke S, Frank J, Kasper M. P2X7R-dependent regulation of glycogen synthase kinase 3β and claudin-18 in alveolar epithelial type I cells of mice lung. Histochem Cell Biol. 2016;146:757-768 pubmed
  4. Giannuzzo A, Saccomano M, Napp J, Ellegaard M, Alves F, Novak I. Targeting of the P2X7 receptor in pancreatic cancer and stellate cells. Int J Cancer. 2016;139:2540-52 pubmed publisher
  5. de Torre Minguela C, Barberà Cremades M, Gómez A, Martín Sánchez F, Pelegrín P. Macrophage activation and polarization modify P2X7 receptor secretome influencing the inflammatory process. Sci Rep. 2016;6:22586 pubmed publisher
  6. Karmakar M, Katsnelson M, Dubyak G, Pearlman E. Neutrophil P2X7 receptors mediate NLRP3 inflammasome-dependent IL-1β secretion in response to ATP. Nat Commun. 2016;7:10555 pubmed publisher
  7. Gómez Villafuertes R, García Huerta P, Díaz Hernández J, Miras Portugal M. PI3K/Akt signaling pathway triggers P2X7 receptor expression as a pro-survival factor of neuroblastoma cells under limiting growth conditions. Sci Rep. 2015;5:18417 pubmed publisher
  8. Jimenez Mateos E, Arribas Blázquez M, Sanz Rodriguez A, Concannon C, Olivos Ore L, Reschke C, et al. microRNA targeting of the P2X7 purinoceptor opposes a contralateral epileptogenic focus in the hippocampus. Sci Rep. 2015;5:17486 pubmed publisher
  9. Faroni A, Smith R, Procacci P, Castelnovo L, Puccianti E, Reid A, et al. Purinergic signaling mediated by P2X7 receptors controls myelination in sciatic nerves. J Neurosci Res. 2014;92:1259-69 pubmed publisher