This is a Validated Antibody Database (VAD) review about rat Nras, based on 42 published articles (read how Labome selects the articles), using Nras antibody in all methods. It is aimed to help Labome visitors find the most suited Nras antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Knockout validation
Santa Cruz Biotechnology
mouse monoclonal (F155)
  • western blot knockout validation; human; 1:1000; fig s2
Santa Cruz Biotechnology Nras antibody (Santa Cruz, sc-31) was used in western blot knockout validation on human samples at 1:1000 (fig s2). Cell Death Dis (2016) ncbi
Santa Cruz Biotechnology
mouse monoclonal (F155)
  • western blot knockout validation; mouse; fig 1
In order to explore how different Ras isoforms contribute to transformation, Santa Cruz Biotechnology Nras antibody (Santa, sc-31) was used in western blot knockout validation on mouse samples (fig 1). Mol Cell Biol (2007) ncbi
Santa Cruz Biotechnology
mouse monoclonal (F155)
  • western blot; human; 1:150; loading ...; fig 3f
Santa Cruz Biotechnology Nras antibody (Santa Cruz Biotechnology, sc-31) was used in western blot on human samples at 1:150 (fig 3f). Cancers (Basel) (2021) ncbi
mouse monoclonal (F155)
  • immunohistochemistry; mouse; loading ...; fig 3b
Santa Cruz Biotechnology Nras antibody (Santa Cruz, sc-31) was used in immunohistochemistry on mouse samples (fig 3b). Cell Rep (2021) ncbi
mouse monoclonal (F155)
  • immunohistochemistry - frozen section; mouse; 1:50; loading ...; fig 1d
Santa Cruz Biotechnology Nras antibody (Santa Cruz, sc-31) was used in immunohistochemistry - frozen section on mouse samples at 1:50 (fig 1d). elife (2019) ncbi
mouse monoclonal (F155)
  • immunohistochemistry - paraffin section; mouse; 1:300; loading ...; fig 1e, s2c
Santa Cruz Biotechnology Nras antibody (Santa Cruz, sc-31) was used in immunohistochemistry - paraffin section on mouse samples at 1:300 (fig 1e, s2c). Sci Adv (2019) ncbi
mouse monoclonal (F155)
  • immunoprecipitation; human; loading ...; fig s2d
  • western blot; human; loading ...; fig s1b
Santa Cruz Biotechnology Nras antibody (Santa Cruz, sc-31) was used in immunoprecipitation on human samples (fig s2d) and in western blot on human samples (fig s1b). Cell (2019) ncbi
mouse monoclonal (F155)
  • western blot; mouse; 1:1000; loading ...; fig s1c
Santa Cruz Biotechnology Nras antibody (Santa Cruz Biotechnology, Inc, sc-31) was used in western blot on mouse samples at 1:1000 (fig s1c). Nat Commun (2018) ncbi
mouse monoclonal (F155)
  • other; human; loading ...; fig 4c
Santa Cruz Biotechnology Nras antibody (SantaCruz, sc-31) was used in other on human samples (fig 4c). Cancer Cell (2018) ncbi
mouse monoclonal (F155)
  • immunohistochemistry - paraffin section; human; loading ...; fig s2a
  • immunoprecipitation; human; loading ...; tbl 1
  • immunocytochemistry; human; 1:100; loading ...; fig 6b
  • western blot; human; loading ...; tbl 1
In order to evaluation isoform- and mutation-specific RAS antibodies, Santa Cruz Biotechnology Nras antibody (Santa Cruz, SC-31) was used in immunohistochemistry - paraffin section on human samples (fig s2a), in immunoprecipitation on human samples (tbl 1), in immunocytochemistry on human samples at 1:100 (fig 6b) and in western blot on human samples (tbl 1). Sci Signal (2017) ncbi
mouse monoclonal (F155)
  • western blot; human; loading ...; fig 2c
In order to study the effect of GNAQ mutations and GNA11/MAPK pathway activation in uveal melanoma, Santa Cruz Biotechnology Nras antibody (Santa Cruz, sc-31) was used in western blot on human samples (fig 2c). Cancer Cell (2017) ncbi
mouse monoclonal (F155)
  • reverse phase protein lysate microarray; human; loading ...; fig st6
In order to characterize the molecular identity of uterine carcinosarcomas., Santa Cruz Biotechnology Nras antibody (Santa Cruz, sc-31) was used in reverse phase protein lysate microarray on human samples (fig st6). Cancer Cell (2017) ncbi
mouse monoclonal (F155)
  • reverse phase protein lysate microarray; human; loading ...; fig 3a
In order to describe the features of 228 primary cervical cancers, Santa Cruz Biotechnology Nras antibody (SantaCruz, sc-31) was used in reverse phase protein lysate microarray on human samples (fig 3a). Nature (2017) ncbi
mouse monoclonal (F155)
  • western blot; human; loading ...
In order to analyze the context specificity of signaling networks within a causal conceptual framework using reverse-phase protein array time-course assays and network analysis approaches, Santa Cruz Biotechnology Nras antibody (Santa Cruz, sc-31) was used in western blot on human samples . Cell Syst (2017) ncbi
mouse monoclonal (F132)
  • western blot; human; loading ...; fig 7a
In order to explore the role of the S100A7 in oral squamous cell carcinoma, Santa Cruz Biotechnology Nras antibody (Santa Cruz, S-32) was used in western blot on human samples (fig 7a). Cancer Gene Ther (2016) ncbi
mouse monoclonal (F155)
  • western blot; mouse; fig 6
Santa Cruz Biotechnology Nras antibody (Santa Cruz, sc-31) was used in western blot on mouse samples (fig 6). Oncotarget (2016) ncbi
mouse monoclonal (F155)
  • western blot knockout validation; human; 1:1000; fig s2
Santa Cruz Biotechnology Nras antibody (Santa Cruz, sc-31) was used in western blot knockout validation on human samples at 1:1000 (fig s2). Cell Death Dis (2016) ncbi
mouse monoclonal (F155)
  • western blot; human; loading ...; fig 5b
Santa Cruz Biotechnology Nras antibody (Santa Cruz Biotechnology, sc-31) was used in western blot on human samples (fig 5b). FEBS Lett (2016) ncbi
mouse monoclonal (F155)
  • immunohistochemistry - frozen section; mouse; fig 7
Santa Cruz Biotechnology Nras antibody (Santa Cruz, sc-31) was used in immunohistochemistry - frozen section on mouse samples (fig 7). Cancer Discov (2016) ncbi
rat monoclonal (259)
  • immunoprecipitation; human; fig 6
  • western blot; human; fig 6
Santa Cruz Biotechnology Nras antibody (Santa Cruz, sc-35l) was used in immunoprecipitation on human samples (fig 6) and in western blot on human samples (fig 6). Oncotarget (2016) ncbi
mouse monoclonal (C-4)
  • western blot; mouse; fig 1
  • western blot; human; fig 1
Santa Cruz Biotechnology Nras antibody (Santa Cruz Biotechnology, sc-166691) was used in western blot on mouse samples (fig 1) and in western blot on human samples (fig 1). Cell Commun Signal (2016) ncbi
mouse monoclonal (F155)
  • western blot; mouse; loading ...; fig 1a
In order to present the role of Kras in B cell lymphopoiesis, Santa Cruz Biotechnology Nras antibody (Santa Cruz, sc-31) was used in western blot on mouse samples (fig 1a). J Immunol (2016) ncbi
mouse monoclonal (F155)
  • western blot; human; loading ...; fig 5c
Santa Cruz Biotechnology Nras antibody (Santa Cruz Biotechnology, SC-31) was used in western blot on human samples (fig 5c). Biochem J (2015) ncbi
mouse monoclonal (F155)
  • immunohistochemistry - paraffin section; human; fig 1
Santa Cruz Biotechnology Nras antibody (Santa Cruz, sc-31) was used in immunohistochemistry - paraffin section on human samples (fig 1). Oncotarget (2015) ncbi
mouse monoclonal (F155)
  • immunohistochemistry - paraffin section; mouse; 1:100; loading ...
Santa Cruz Biotechnology Nras antibody (Santa Cruz, Sc-31) was used in immunohistochemistry - paraffin section on mouse samples at 1:100. elife (2015) ncbi
mouse monoclonal (C-4)
  • western blot; human
Santa Cruz Biotechnology Nras antibody (Santa, sc-166691) was used in western blot on human samples . Oncogene (2014) ncbi
mouse monoclonal (F155)
  • western blot; human
Santa Cruz Biotechnology Nras antibody (Santa Cruz Biotechnology, sc-31) was used in western blot on human samples . Biochem J (2013) ncbi
mouse monoclonal (F155)
  • western blot; human
Santa Cruz Biotechnology Nras antibody (Santa Cruz, sc-31) was used in western blot on human samples . J Biol Chem (2013) ncbi
mouse monoclonal (F155)
  • western blot; hamsters
Santa Cruz Biotechnology Nras antibody (Santa Cruz Biotechnology, sc-31) was used in western blot on hamsters samples . Mol Cell Biol (2013) ncbi
mouse monoclonal (F155)
  • immunocytochemistry; dogs
  • western blot; dogs
Santa Cruz Biotechnology Nras antibody (Santa Cruz Biotechnology, sc-31) was used in immunocytochemistry on dogs samples and in western blot on dogs samples . J Biol Chem (2012) ncbi
mouse monoclonal (F155)
  • western blot knockout validation; mouse; fig 1
In order to explore how different Ras isoforms contribute to transformation, Santa Cruz Biotechnology Nras antibody (Santa, sc-31) was used in western blot knockout validation on mouse samples (fig 1). Mol Cell Biol (2007) ncbi
BD Biosciences
mouse monoclonal (18/Ras)
  • western blot; human; loading ...; fig 1a
BD Biosciences Nras antibody (BD Transduction Laboratories, 610001) was used in western blot on human samples (fig 1a). J Cell Biol (2021) ncbi
mouse monoclonal (18/Ras)
  • western blot; human; 1:1000; fig 1e
BD Biosciences Nras antibody (BD Sciences, 610001) was used in western blot on human samples at 1:1000 (fig 1e). Aging (Albany NY) (2021) ncbi
mouse monoclonal (18/Ras)
  • western blot; rat; 1:2000; loading ...; fig 1d
BD Biosciences Nras antibody (BD Biosciences, 610001) was used in western blot on rat samples at 1:2000 (fig 1d). Neuron (2018) ncbi
mouse monoclonal (18/Ras)
  • western blot; human; 1:1000; loading ...; fig 1b
In order to identify Aurora kinase A as a novel Ras binding protein, BD Biosciences Nras antibody (BD Transduction Laboratories, 610002) was used in western blot on human samples at 1:1000 (fig 1b). Oncotarget (2017) ncbi
mouse monoclonal (18/Ras)
  • western blot; human; loading ...; fig 1a
In order to study the effect of PIK3CA in breast cancer., BD Biosciences Nras antibody (BD Bioscience, 610001) was used in western blot on human samples (fig 1a). PLoS ONE (2016) ncbi
mouse monoclonal (18/Ras)
  • western blot; human; fig 6
BD Biosciences Nras antibody (BD Biosciences, 610001) was used in western blot on human samples (fig 6). Genome Biol (2016) ncbi
mouse monoclonal (18/Ras)
  • western blot; mouse; loading ...; fig 1a
In order to present the role of Kras in B cell lymphopoiesis, BD Biosciences Nras antibody (BD Biosciences, 610001) was used in western blot on mouse samples (fig 1a). J Immunol (2016) ncbi
mouse monoclonal (18/Ras)
  • western blot; mouse; 1:1000; loading ...; fig 3a
BD Biosciences Nras antibody (BD Bioscience, 610001) was used in western blot on mouse samples at 1:1000 (fig 3a). PLoS ONE (2015) ncbi
mouse monoclonal (18/Ras)
  • western blot; human; fig 1
BD Biosciences Nras antibody (BD Transduction Laboratories, 610001) was used in western blot on human samples (fig 1). Carcinogenesis (2015) ncbi
mouse monoclonal (18/Ras)
  • western blot; human; fig 1
In order to analyze the contribution of genetic alterations and cell type of origin in breast cancer phenotypes, BD Biosciences Nras antibody (BD Bioscience, 610001) was used in western blot on human samples (fig 1). Oncotarget (2015) ncbi
mouse monoclonal (18/Ras)
  • immunohistochemistry - paraffin section; human; fig 6
  • western blot; human; fig 2
  • immunohistochemistry - paraffin section; mouse; fig 6
BD Biosciences Nras antibody (BD Transduction labs, 61001) was used in immunohistochemistry - paraffin section on human samples (fig 6), in western blot on human samples (fig 2) and in immunohistochemistry - paraffin section on mouse samples (fig 6). Cell Cycle (2015) ncbi
mouse monoclonal (18/Ras)
  • western blot; mouse; fig 8
BD Biosciences Nras antibody (BD Biosciences, 610001) was used in western blot on mouse samples (fig 8). Mol Cell Biol (2015) ncbi
mouse monoclonal (18/Ras)
  • western blot; human
BD Biosciences Nras antibody (BD Biosciences, 18/Ras) was used in western blot on human samples . FASEB J (2014) ncbi
mouse monoclonal (18/Ras)
  • immunocytochemistry; rat
  • western blot; rat
In order to study the effect of a novel amyloid-binding small molecule on Ras-mediated spinogenesis, BD Biosciences Nras antibody (BD Biosciences, 610001) was used in immunocytochemistry on rat samples and in western blot on rat samples . J Neurosci (2013) ncbi
mouse monoclonal (18/Ras)
  • western blot; hamsters
BD Biosciences Nras antibody (BD Transduction Laboratories, 610001) was used in western blot on hamsters samples . Mol Cell Biol (2013) ncbi
mouse monoclonal (18/Ras)
  • immunocytochemistry; dogs
  • western blot; dogs
BD Biosciences Nras antibody (BD Transduction Laboratories, 610001) was used in immunocytochemistry on dogs samples and in western blot on dogs samples . J Biol Chem (2012) ncbi
Articles Reviewed
  1. Leon K, Buj R, Lesko E, Dahl E, Chen C, Tangudu N, et al. DOT1L modulates the senescence-associated secretory phenotype through epigenetic regulation of IL1A. J Cell Biol. 2021;220: pubmed publisher
  2. Loureiro J, Raimundo L, Calheiros J, Carvalho C, Barcherini V, Lima N, et al. Targeting p53 for Melanoma Treatment: Counteracting Tumour Proliferation, Dissemination and Therapeutic Resistance. Cancers (Basel). 2021;13: pubmed publisher
  3. Goncalves S, Yin K, Ito Y, Chan A, Olan I, Gough S, et al. COX2 regulates senescence secretome composition and senescence surveillance through PGE2. Cell Rep. 2021;34:108860 pubmed publisher
  4. Buj R, Leon K, Anguelov M, Aird K. Suppression of p16 alleviates the senescence-associated secretory phenotype. Aging (Albany NY). 2021;13:3290-3312 pubmed publisher
  5. McMahon M, Contreras A, Holm M, Uechi T, Forester C, Pang X, et al. A single H/ACA small nucleolar RNA mediates tumor suppression downstream of oncogenic RAS. elife. 2019;8: pubmed publisher
  6. Hari P, Millar F, Tarrats N, Birch J, Quintanilla A, Rink C, et al. The innate immune sensor Toll-like receptor 2 controls the senescence-associated secretory phenotype. Sci Adv. 2019;5:eaaw0254 pubmed publisher
  7. Yin C, Zhu B, Zhang T, Liu T, Chen S, Liu Y, et al. Pharmacological Targeting of STK19 Inhibits Oncogenic NRAS-Driven Melanomagenesis. Cell. 2019;176:1113-1127.e16 pubmed publisher
  8. Hyrenius Wittsten A, Pilheden M, Sturesson H, Hansson J, Walsh M, Song G, et al. De novo activating mutations drive clonal evolution and enhance clonal fitness in KMT2A-rearranged leukemia. Nat Commun. 2018;9:1770 pubmed publisher
  9. Zhang L, Zhang P, Wang G, Zhang H, Zhang Y, Yu Y, et al. Ras and Rap Signal Bidirectional Synaptic Plasticity via Distinct Subcellular Microdomains. Neuron. 2018;98:783-800.e4 pubmed publisher
  10. Ng P, Li J, Jeong K, Shao S, Chen H, Tsang Y, et al. Systematic Functional Annotation of Somatic Mutations in Cancer. Cancer Cell. 2018;33:450-462.e10 pubmed publisher
  11. Waters A, Ozkan Dagliyan I, Vaseva A, Fer N, Strathern L, Hobbs G, et al. Evaluation of the selectivity and sensitivity of isoform- and mutation-specific RAS antibodies. Sci Signal. 2017;10: pubmed publisher
  12. Chen X, Wu Q, Depeille P, Chen P, Thornton S, Kalirai H, et al. RasGRP3 Mediates MAPK Pathway Activation in GNAQ Mutant Uveal Melanoma. Cancer Cell. 2017;31:685-696.e6 pubmed publisher
  13. Cherniack A, Shen H, Walter V, Stewart C, Murray B, Bowlby R, et al. Integrated Molecular Characterization of Uterine Carcinosarcoma. Cancer Cell. 2017;31:411-423 pubmed publisher
  14. Umstead M, Xiong J, Qi Q, Du Y, Fu H. Aurora kinase A interacts with H-Ras and potentiates Ras-MAPK signaling. Oncotarget. 2017;8:28359-28372 pubmed publisher
  15. . Integrated genomic and molecular characterization of cervical cancer. Nature. 2017;543:378-384 pubmed publisher
  16. Hill S, Nesser N, Johnson Camacho K, Jeffress M, Johnson A, Boniface C, et al. Context Specificity in Causal Signaling Networks Revealed by Phosphoprotein Profiling. Cell Syst. 2017;4:73-83.e10 pubmed publisher
  17. Bhagirath D, Zhao X, Mirza S, West W, Band H, Band V. Mutant PIK3CA Induces EMT in a Cell Type Specific Manner. PLoS ONE. 2016;11:e0167064 pubmed publisher
  18. Dey K, Bharti R, Dey G, Pal I, Rajesh Y, Chavan S, et al. S100A7 has an oncogenic role in oral squamous cell carcinoma by activating p38/MAPK and RAB2A signaling pathway. Cancer Gene Ther. 2016;23:382-391 pubmed publisher
  19. Nowacka J, Baumgartner C, Pelorosso C, Roth M, Zuber J, Baccarini M. MEK1 is required for the development of NRAS-driven leukemia. Oncotarget. 2016;7:80113-80130 pubmed publisher
  20. Anta B, Pérez Rodríguez A, Castro J, García Domínguez C, Ibiza S, Martínez N, et al. PGA1-induced apoptosis involves specific activation of H-Ras and N-Ras in cellular endomembranes. Cell Death Dis. 2016;7:e2311 pubmed publisher
  21. Nelson D, Jaber Hijazi F, Cole J, Robertson N, Pawlikowski J, Norris K, et al. Mapping H4K20me3 onto the chromatin landscape of senescent cells indicates a function in control of cell senescence and tumor suppression through preservation of genetic and epigenetic stability. Genome Biol. 2016;17:158 pubmed publisher
  22. Ye S, Song W, Xu X, Zhao X, Yang L. IGF2BP2 promotes colorectal cancer cell proliferation and survival through interfering with RAF-1 degradation by miR-195. FEBS Lett. 2016;590:1641-50 pubmed publisher
  23. Tasdemir N, Banito A, Roe J, Alonso Curbelo D, Camiolo M, Tschaharganeh D, et al. BRD4 Connects Enhancer Remodeling to Senescence Immune Surveillance. Cancer Discov. 2016;6:612-29 pubmed publisher
  24. Carrero Z, Kollareddy M, Chauhan K, Ramakrishnan G, Martinez L. Mutant p53 protects ETS2 from non-canonical COP1/DET1 dependent degradation. Oncotarget. 2016;7:12554-67 pubmed publisher
  25. Hennig A, Markwart R, Wolff K, Schubert K, Cui Y, Prior I, et al. Feedback activation of neurofibromin terminates growth factor-induced Ras activation. Cell Commun Signal. 2016;14:5 pubmed publisher
  26. Chen Y, Zheng Y, You X, Yu M, Fu G, Su X, et al. Kras Is Critical for B Cell Lymphopoiesis. J Immunol. 2016;196:1678-85 pubmed publisher
  27. Cho S, Park H, Jarboe E, Peterson C, Bae Y, Janát Amsbury M. Design and Characterization of Bioengineered Cancer-Like Stem Cells. PLoS ONE. 2015;10:e0141172 pubmed publisher
  28. Lenain C, Gusyatiner O, Douma S, van den Broek B, Peeper D. Autophagy-mediated degradation of nuclear envelope proteins during oncogene-induced senescence. Carcinogenesis. 2015;36:1263-74 pubmed publisher
  29. Kloet D, Polderman P, Eijkelenboom A, Smits L, van Triest M, van den Berg M, et al. FOXO target gene CTDSP2 regulates cell cycle progression through Ras and p21(Cip1/Waf1). Biochem J. 2015;469:289-98 pubmed publisher
  30. Bhagirath D, Zhao X, West W, Qiu F, Band H, Band V. Cell type of origin as well as genetic alterations contribute to breast cancer phenotypes. Oncotarget. 2015;6:9018-30 pubmed
  31. Zhu M, Guo J, Li W, Lu Y, Fu S, Xie X, et al. Hepatitis B virus X protein induces expression of alpha-fetoprotein and activates PI3K/mTOR signaling pathway in liver cells. Oncotarget. 2015;6:12196-208 pubmed
  32. Raouf S, Weston C, Yucel N. Registered report: senescence surveillance of pre-malignant hepatocytes limits liver cancer development. elife. 2015;4: pubmed publisher
  33. Bele A, Mirza S, Zhang Y, Ahmad Mir R, Lin S, Kim J, et al. The cell cycle regulator ecdysoneless cooperates with H-Ras to promote oncogenic transformation of human mammary epithelial cells. Cell Cycle. 2015;14:990-1000 pubmed publisher
  34. Salotti J, Sakchaisri K, Tourtellotte W, Johnson P. An Arf-Egr-C/EBPβ pathway linked to ras-induced senescence and cancer. Mol Cell Biol. 2015;35:866-83 pubmed publisher
  35. Hoermann G, Blatt K, Greiner G, Putz E, Berger A, Herrmann H, et al. CD52 is a molecular target in advanced systemic mastocytosis. FASEB J. 2014;28:3540-51 pubmed publisher
  36. Zaganjor E, Osborne J, Weil L, Díaz Martínez L, Gonzales J, Singel S, et al. Ras regulates kinesin 13 family members to control cell migration pathways in transformed human bronchial epithelial cells. Oncogene. 2014;33:5457-66 pubmed publisher
  37. Megill A, Lee T, Dibattista A, Song J, Spitzer M, Rubinshtein M, et al. A tetra(ethylene glycol) derivative of benzothiazole aniline enhances Ras-mediated spinogenesis. J Neurosci. 2013;33:9306-18 pubmed publisher
  38. BENTLEY C, Jurinka S, Kljavin N, Vartanian S, Ramani S, Gonzalez L, et al. A requirement for wild-type Ras isoforms in mutant KRas-driven signalling and transformation. Biochem J. 2013;452:313-20 pubmed publisher
  39. Vartanian S, BENTLEY C, Brauer M, Li L, Shirasawa S, Sasazuki T, et al. Identification of mutant K-Ras-dependent phenotypes using a panel of isogenic cell lines. J Biol Chem. 2013;288:2403-13 pubmed publisher
  40. van der Hoeven D, Cho K, Ma X, Chigurupati S, Parton R, Hancock J. Fendiline inhibits K-Ras plasma membrane localization and blocks K-Ras signal transmission. Mol Cell Biol. 2013;33:237-51 pubmed publisher
  41. Cho K, Park J, Piggott A, Salim A, Gorfe A, Parton R, et al. Staurosporines disrupt phosphatidylserine trafficking and mislocalize Ras proteins. J Biol Chem. 2012;287:43573-84 pubmed publisher
  42. Fotiadou P, Takahashi C, Rajabi H, Ewen M. Wild-type NRas and KRas perform distinct functions during transformation. Mol Cell Biol. 2007;27:6742-55 pubmed