This is a Validated Antibody Database (VAD) review about rat Nol3, based on 13 published articles (read how Labome selects the articles), using Nol3 antibody in all methods. It is aimed to help Labome visitors find the most suited Nol3 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Nol3 synonym: Arc; nucleolar protein 3; apoptosis repressor with CARD; nucleolar protein 3 (apoptosis repressor with CARD domain)

Knockout validation
Synaptic Systems
rabbit polyclonal (/)
  • immunocytochemistry knockout validation; mouse; fig s4c
Synaptic Systems Nol3 antibody (Synaptic Systems, 156-003) was used in immunocytochemistry knockout validation on mouse samples (fig s4c). Cell (2018) ncbi
Synaptic Systems
rabbit polyclonal (/)
  • immunocytochemistry knockout validation; mouse; fig s4c
Synaptic Systems Nol3 antibody (Synaptic Systems, 156-003) was used in immunocytochemistry knockout validation on mouse samples (fig s4c). Cell (2018) ncbi
rabbit polyclonal (/)
  • western blot; mouse; fig 7
In order to analyze selective partitioning into complexes and supercomplexes during synapse maturation by NMDA receptors, Synaptic Systems Nol3 antibody (Synaptic Systems, 156 003) was used in western blot on mouse samples (fig 7). Nat Commun (2016) ncbi
rabbit polyclonal (/)
  • immunohistochemistry; rat; 1:1000; fig 1
Synaptic Systems Nol3 antibody (Synaptic system, 156-002) was used in immunohistochemistry on rat samples at 1:1000 (fig 1). Front Cell Neurosci (2016) ncbi
rabbit polyclonal (/)
  • immunohistochemistry; mouse; 1:1000; fig s1
Synaptic Systems Nol3 antibody (Synaptic Systems, 156 003) was used in immunohistochemistry on mouse samples at 1:1000 (fig s1). Sci Rep (2016) ncbi
rabbit polyclonal (/)
  • western blot; rat; 1:500; fig 4
In order to elucidate neuropathic pain and the critical role of intracellular mGluR5, Synaptic Systems Nol3 antibody (Synaptic Systems, 156-003) was used in western blot on rat samples at 1:500 (fig 4). Nat Commun (2016) ncbi
rabbit polyclonal (/)
  • immunohistochemistry; mouse; fig 6
Synaptic Systems Nol3 antibody (Synaptic Systems, 156-003) was used in immunohistochemistry on mouse samples (fig 6). Sci Rep (2015) ncbi
rabbit polyclonal (/)
  • western blot; rat; 1:2000; loading ...; fig 2b
Synaptic Systems Nol3 antibody (Synaptic Systems, 156002) was used in western blot on rat samples at 1:2000 (fig 2b). Transl Psychiatry (2015) ncbi
rabbit polyclonal (/)
  • immunohistochemistry - frozen section; mouse; 1:12,000; fig s5
Synaptic Systems Nol3 antibody (Synaptic Systems, 156-003) was used in immunohistochemistry - frozen section on mouse samples at 1:12,000 (fig s5). Nat Neurosci (2015) ncbi
rabbit polyclonal (/)
  • immunohistochemistry - free floating section; mouse; 1:1000
Synaptic Systems Nol3 antibody (Synaptic Systems, 156003) was used in immunohistochemistry - free floating section on mouse samples at 1:1000. J Neurosci (2015) ncbi
Santa Cruz Biotechnology
mouse monoclonal (F-11)
  • western blot; rat; loading ...; fig 1a
Santa Cruz Biotechnology Nol3 antibody (Santa Cruz, sc-374177) was used in western blot on rat samples (fig 1a). Redox Biol (2019) ncbi
BD Biosciences
mouse monoclonal (40/Arc)
  • immunohistochemistry; rat; fig 2
In order to research the role of BDNF-induced LTP in adult hippocampal neurogenesis, BD Biosciences Nol3 antibody (BD Biosciences, 612603) was used in immunohistochemistry on rat samples (fig 2). Sci Rep (2016) ncbi
mouse monoclonal (40/Arc)
  • other; human; loading ...; fig st1
In order to use size exclusion chromatography-microsphere-based affinity proteomics to study clinical samples obtained from pediatric acute leukemia patients, BD Biosciences Nol3 antibody (BD, 40) was used in other on human samples (fig st1). Mol Cell Proteomics (2016) ncbi
mouse monoclonal (40/Arc)
  • western blot; human; 1:1000; fig 7
BD Biosciences Nol3 antibody (BD Transduction Laboratories, 612603) was used in western blot on human samples at 1:1000 (fig 7). Sci Rep (2013) ncbi
Articles Reviewed
  1. Xu T, Ding W, Ao X, Chu X, Wan Q, Wang Y, et al. ARC regulates programmed necrosis and myocardial ischemia/reperfusion injury through the inhibition of mPTP opening. Redox Biol. 2019;20:414-426 pubmed publisher
  2. Pastuzyn E, Day C, Kearns R, Kyrke Smith M, Taibi A, McCormick J, et al. The Neuronal Gene Arc Encodes a Repurposed Retrotransposon Gag Protein that Mediates Intercellular RNA Transfer. Cell. 2018;172:275-288.e18 pubmed publisher
  3. Frank R, Komiyama N, Ryan T, Zhu F, O Dell T, Grant S. NMDA receptors are selectively partitioned into complexes and supercomplexes during synapse maturation. Nat Commun. 2016;7:11264 pubmed publisher
  4. Wang X, Song X, Wu L, Nadler J, Zhan R. Persistent Hyperactivity of Hippocampal Dentate Interneurons After a Silent Period in the Rat Pilocarpine Model of Epilepsy. Front Cell Neurosci. 2016;10:94 pubmed publisher
  5. Kuipers S, Trentani A, Tiron A, Mao X, Kuhl D, Bramham C. BDNF-induced LTP is associated with rapid Arc/Arg3.1-dependent enhancement in adult hippocampal neurogenesis. Sci Rep. 2016;6:21222 pubmed publisher
  6. Nakayama D, Hashikawa Yamasaki Y, Ikegaya Y, Matsuki N, Nomura H. Late Arc/Arg3.1 expression in the basolateral amygdala is essential for persistence of newly-acquired and reactivated contextual fear memories. Sci Rep. 2016;6:21007 pubmed publisher
  7. Vincent K, Cornea V, Jong Y, Laferrière A, Kumar N, Mickeviciute A, et al. Intracellular mGluR5 plays a critical role in neuropathic pain. Nat Commun. 2016;7:10604 pubmed publisher
  8. Kanderová V, Kuzilkova D, Stuchly J, Vaskova M, Brdicka T, Fiser K, et al. High-resolution Antibody Array Analysis of Childhood Acute Leukemia Cells. Mol Cell Proteomics. 2016;15:1246-61 pubmed publisher
  9. Scandaglia M, Benito E, Morenilla Palao C, Fiorenza A, Del Blanco B, Coca Y, et al. Fine-tuned SRF activity controls asymmetrical neuronal outgrowth: implications for cortical migration, neural tissue lamination and circuit assembly. Sci Rep. 2015;5:17470 pubmed publisher
  10. Quinn R, Brown A, Goldie B, Levi E, Dickson P, Smith D, et al. Distinct miRNA expression in dorsal striatal subregions is associated with risk for addiction in rats. Transl Psychiatry. 2015;5:e503 pubmed publisher
  11. Orr A, Hsiao E, Wang M, Ho K, Kim D, Wang X, et al. Astrocytic adenosine receptor A2A and Gs-coupled signaling regulate memory. Nat Neurosci. 2015;18:423-34 pubmed publisher
  12. Nakayama D, Iwata H, Teshirogi C, Ikegaya Y, Matsuki N, Nomura H. Long-delayed expression of the immediate early gene Arc/Arg3.1 refines neuronal circuits to perpetuate fear memory. J Neurosci. 2015;35:819-30 pubmed publisher
  13. Whittington R, Bretteville A, Virag L, Emala C, Maurin T, Marcouiller F, et al. Anesthesia-induced hypothermia mediates decreased ARC gene and protein expression through ERK/MAPK inactivation. Sci Rep. 2013;3:1388 pubmed publisher