This is a Validated Antibody Database (VAD) review about rat Nbr1, based on 10 published articles (read how Labome selects the articles), using Nbr1 antibody in all methods. It is aimed to help Labome visitors find the most suited Nbr1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Nbr1 synonym: Ca125; RGD1311421

Santa Cruz Biotechnology
mouse monoclonal (4BR)
  • immunohistochemistry - paraffin section; human; 1:50; fig s2e
  • immunohistochemistry - paraffin section; rat; 1:50; fig s2e
  • western blot; rat; 1:400; loading ...; fig s2b
Santa Cruz Biotechnology Nbr1 antibody (Santa Cruz, sc-130380) was used in immunohistochemistry - paraffin section on human samples at 1:50 (fig s2e), in immunohistochemistry - paraffin section on rat samples at 1:50 (fig s2e) and in western blot on rat samples at 1:400 (fig s2b). Theranostics (2021) ncbi
mouse monoclonal (4BR)
  • western blot; human; 1:500; loading ...; fig 2g
Santa Cruz Biotechnology Nbr1 antibody (Santa Cruz, 4BR) was used in western blot on human samples at 1:500 (fig 2g). Nature (2020) ncbi
mouse monoclonal (4BR)
  • western blot; human; loading ...; fig s1d
Santa Cruz Biotechnology Nbr1 antibody (Santa Cruz, sc-130380) was used in western blot on human samples (fig s1d). Dev Cell (2019) ncbi
mouse monoclonal (4BR)
  • western blot; human; loading ...; fig s6b
Santa Cruz Biotechnology Nbr1 antibody (Santa, sc-130380) was used in western blot on human samples (fig s6b). Autophagy (2019) ncbi
mouse monoclonal (4BR)
  • immunocytochemistry; human; 1:100; loading ...; fig s3b
In order to recognize the inner mitochondrial membrane protein, prohibitin 2, as a crucial mitophagy receptor involved in targeting mitochondria for autophagic degradation, Santa Cruz Biotechnology Nbr1 antibody (Santa Cruz, sc-130380) was used in immunocytochemistry on human samples at 1:100 (fig s3b). Cell (2017) ncbi
mouse monoclonal (4BR)
  • western blot; human; fig 2
  • western blot; mouse; fig 4
Santa Cruz Biotechnology Nbr1 antibody (Santa Cruz, sc-130380) was used in western blot on human samples (fig 2) and in western blot on mouse samples (fig 4). Cell Death Dis (2015) ncbi
mouse monoclonal (4BR)
  • western blot; human
Santa Cruz Biotechnology Nbr1 antibody (Santa Cruz Biotechnology, sc-130380) was used in western blot on human samples . Cell Death Differ (2014) ncbi
Abnova
mouse monoclonal (6B11)
  • western blot; human; 1:1000; loading ...; fig 4e
Abnova Nbr1 antibody (Abnova, H00004077-M01) was used in western blot on human samples at 1:1000 (fig 4e). Autophagy (2017) ncbi
mouse monoclonal (6B11)
  • western blot; human; fig 2
In order to determine stress resistance to breast cancer cells and neuroblastoma by BAG3 function and estrogen receptor alpha that regulates non-canonical autophagy, Abnova Nbr1 antibody (Abnova, 00004077-M01) was used in western blot on human samples (fig 2). Cell Death Dis (2015) ncbi
mouse monoclonal (6B11)
  • western blot; human; 1:5000; fig 3
Abnova Nbr1 antibody (Abnova, H00004077-M01) was used in western blot on human samples at 1:5000 (fig 3). Nat Cell Biol (2014) ncbi
Articles Reviewed
  1. Zheng Q, Shen H, Tong Z, Cheng L, Xu Y, Feng Z, et al. A thermosensitive, reactive oxygen species-responsive, MR409-encapsulated hydrogel ameliorates disc degeneration in rats by inhibiting the secretory autophagy pathway. Theranostics. 2021;11:147-163 pubmed publisher
  2. Yamamoto K, Venida A, Yano J, Biancur D, Kakiuchi M, Gupta S, et al. Autophagy promotes immune evasion of pancreatic cancer by degrading MHC-I. Nature. 2020;581:100-105 pubmed publisher
  3. Princely Abudu Y, Pankiv S, Mathai B, Håkon Lystad A, Bindesbøll C, Brenne H, et al. NIPSNAP1 and NIPSNAP2 Act as "Eat Me" Signals for Mitophagy. Dev Cell. 2019;49:509-525.e12 pubmed publisher
  4. Birgisdottir A, Mouilleron S, Bhujabal Z, Wirth M, Sjøttem E, Evjen G, et al. Members of the autophagy class III phosphatidylinositol 3-kinase complex I interact with GABARAP and GABARAPL1 via LIR motifs. Autophagy. 2019;15:1333-1355 pubmed publisher
  5. Law K, Bronte Tinkew D, Di Pietro E, Snowden A, Jones R, Moser A, et al. The peroxisomal AAA ATPase complex prevents pexophagy and development of peroxisome biogenesis disorders. Autophagy. 2017;13:868-884 pubmed publisher
  6. Wei Y, Chiang W, Sumpter R, Mishra P, Levine B. Prohibitin 2 Is an Inner Mitochondrial Membrane Mitophagy Receptor. Cell. 2017;168:224-238.e10 pubmed publisher
  7. Shi J, Fung G, Deng H, Zhang J, Fiesel F, Springer W, et al. NBR1 is dispensable for PARK2-mediated mitophagy regardless of the presence or absence of SQSTM1. Cell Death Dis. 2015;6:e1943 pubmed publisher
  8. Felzen V, Hiebel C, Koziollek Drechsler I, Reißig S, Wolfrum U, Kögel D, et al. Estrogen receptor α regulates non-canonical autophagy that provides stress resistance to neuroblastoma and breast cancer cells and involves BAG3 function. Cell Death Dis. 2015;6:e1812 pubmed publisher
  9. Dowdle W, Nyfeler B, Nagel J, Elling R, Liu S, Triantafellow E, et al. Selective VPS34 inhibitor blocks autophagy and uncovers a role for NCOA4 in ferritin degradation and iron homeostasis in vivo. Nat Cell Biol. 2014;16:1069-79 pubmed publisher
  10. Shi J, Fung G, Piesik P, Zhang J, Luo H. Dominant-negative function of the C-terminal fragments of NBR1 and SQSTM1 generated during enteroviral infection. Cell Death Differ. 2014;21:1432-41 pubmed publisher