This is a Validated Antibody Database (VAD) review about rat Mre11a, based on 19 published articles (read how Labome selects the articles), using Mre11a antibody in all methods. It is aimed to help Labome visitors find the most suited Mre11a antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Mre11a synonym: Mre11; double-strand break repair protein MRE11; double-strand break repair protein MRE11A; MRE11 homolog 1; MRE11 homolog, double strand break repair nuclease A; MRE11 meiotic recombination 11 homolog A; meiotic recombination 11 homolog 1; meiotic recombination 11 homolog A

Knockout validation
Cell Signaling Technology
rabbit polyclonal
  • western blot knockout validation; mouse; fig s1
Cell Signaling Technology Mre11a antibody (Cell Signaling, 4895) was used in western blot knockout validation on mouse samples (fig s1). Nat Struct Mol Biol (2015) ncbi
Abcam
mouse monoclonal (12D7)
  • immunoprecipitation; human; fig 5a
Abcam Mre11a antibody (Abcam, ab214) was used in immunoprecipitation on human samples (fig 5a). Nat Commun (2015) ncbi
mouse monoclonal (12D7)
  • western blot; mouse; fig 5a
  • western blot; human; fig s1c
Abcam Mre11a antibody (Abcam, ab214) was used in western blot on mouse samples (fig 5a) and in western blot on human samples (fig s1c). Cell Death Differ (2016) ncbi
mouse monoclonal (12D7)
  • western blot; human; 1:500; fig s2
Abcam Mre11a antibody (Abcam, ab214) was used in western blot on human samples at 1:500 (fig s2). Nat Cell Biol (2014) ncbi
mouse monoclonal (12D7)
  • immunocytochemistry; mouse
Abcam Mre11a antibody (Abcam, ab214) was used in immunocytochemistry on mouse samples . PLoS ONE (2014) ncbi
mouse monoclonal (12D7)
  • immunocytochemistry; human; 1:200 and 1:750
  • western blot; human
Abcam Mre11a antibody (Abcam, ab214) was used in immunocytochemistry on human samples at 1:200 and 1:750 and in western blot on human samples . PLoS ONE (2014) ncbi
mouse monoclonal (12D7)
  • western blot; human
Abcam Mre11a antibody (Abcam, AB214) was used in western blot on human samples . Oncotarget (2014) ncbi
mouse monoclonal (12D7)
  • immunocytochemistry; human; 1:1000
  • western blot; human; 1:500-1:1000
Abcam Mre11a antibody (Abcam, ab214) was used in immunocytochemistry on human samples at 1:1000 and in western blot on human samples at 1:500-1:1000. PLoS ONE (2013) ncbi
mouse monoclonal (12D7)
  • immunohistochemistry - paraffin section; human; 1:200
Abcam Mre11a antibody (Abcam, ab214) was used in immunohistochemistry - paraffin section on human samples at 1:200. World J Gastroenterol (2013) ncbi
Santa Cruz Biotechnology
mouse monoclonal (18)
  • immunocytochemistry; mouse; 1:500; loading ...; fig s9a
  • western blot; mouse; 1:100; loading ...; fig s13a
  • western blot; human; 1:100; loading ...; fig s12e
Santa Cruz Biotechnology Mre11a antibody (Santa Cruz, SC-135992) was used in immunocytochemistry on mouse samples at 1:500 (fig s9a), in western blot on mouse samples at 1:100 (fig s13a) and in western blot on human samples at 1:100 (fig s12e). Science (2016) ncbi
Novus Biologicals
rabbit polyclonal
  • immunocytochemistry; human; loading ...; fig s5l
  • western blot; human; loading ...; fig s5a
Novus Biologicals Mre11a antibody (Novus, NB 100-142) was used in immunocytochemistry on human samples (fig s5l) and in western blot on human samples (fig s5a). Cell (2019) ncbi
Cell Signaling Technology
rabbit polyclonal
  • western blot; human; 1:1000; fig 2
Cell Signaling Technology Mre11a antibody (Cell Signaling, 4895S) was used in western blot on human samples at 1:1000 (fig 2). Sci Rep (2016) ncbi
rabbit polyclonal
  • western blot; human; fig 1
Cell Signaling Technology Mre11a antibody (Cell Signaling, 4895) was used in western blot on human samples (fig 1). Mol Cancer Res (2016) ncbi
rabbit polyclonal
  • western blot knockout validation; mouse; fig s1
Cell Signaling Technology Mre11a antibody (Cell Signaling, 4895) was used in western blot knockout validation on mouse samples (fig s1). Nat Struct Mol Biol (2015) ncbi
rabbit polyclonal
  • western blot; mouse; fig 6
Cell Signaling Technology Mre11a antibody (Cell Signaling Technology, 4895) was used in western blot on mouse samples (fig 6). Oncogene (2016) ncbi
rabbit polyclonal
  • immunocytochemistry; mouse; 1:200; fig s3
Cell Signaling Technology Mre11a antibody (Cell Signaling, 4895) was used in immunocytochemistry on mouse samples at 1:200 (fig s3). FASEB J (2014) ncbi
BD Biosciences
mouse monoclonal (18/MRE11)
  • other; human; loading ...; fig st1
In order to use size exclusion chromatography-microsphere-based affinity proteomics to study clinical samples obtained from pediatric acute leukemia patients, BD Biosciences Mre11a antibody (BD, 18) was used in other on human samples (fig st1). Mol Cell Proteomics (2016) ncbi
mouse monoclonal (18/MRE11)
  • western blot; human; 1:1000; fig 3
BD Biosciences Mre11a antibody (BD Biosciences, 611366) was used in western blot on human samples at 1:1000 (fig 3). Nucleic Acids Res (2016) ncbi
EMD Millipore
rabbit polyclonal
  • western blot; mouse; fig 1
In order to determine if the capacity for de novo DNA methylation of developmentally regulated loci is preserved in differentiated somatic cells, EMD Millipore Mre11a antibody (Calbiochem, PC388) was used in western blot on mouse samples (fig 1). Nucleic Acids Res (2016) ncbi
rabbit polyclonal
  • immunohistochemistry - paraffin section; human; 1:100; fig s5c
EMD Millipore Mre11a antibody (Calbiochem, PC388) was used in immunohistochemistry - paraffin section on human samples at 1:100 (fig s5c). Nat Commun (2015) ncbi
rabbit polyclonal
  • western blot; human; fig 2
EMD Millipore Mre11a antibody (Millipore, (PC388) was used in western blot on human samples (fig 2). Tumour Biol (2014) ncbi
Articles Reviewed
  1. Jachimowicz R, Beleggia F, Isensee J, Velpula B, Goergens J, Bustos M, et al. UBQLN4 Represses Homologous Recombination and Is Overexpressed in Aggressive Tumors. Cell. 2019;176:505-519.e22 pubmed publisher
  2. Kanakkanthara A, Jeganathan K, Limzerwala J, Baker D, Hamada M, Nam H, et al. Cyclin A2 is an RNA binding protein that controls Mre11 mRNA translation. Science. 2016;353:1549-1552 pubmed
  3. Sun Y, Zheng W, Guo Z, Ju Q, Zhu L, Gao J, et al. A novel TP53 pathway influences the HGS-mediated exosome formation in colorectal cancer. Sci Rep. 2016;6:28083 pubmed publisher
  4. Termanis A, Torrea N, Culley J, Kerr A, Ramsahoye B, Stancheva I. The SNF2 family ATPase LSH promotes cell-autonomous de novo DNA methylation in somatic cells. Nucleic Acids Res. 2016;44:7592-604 pubmed publisher
  5. Kanderová V, Kuzilkova D, Stuchly J, Vaskova M, Brdicka T, Fiser K, et al. High-resolution Antibody Array Analysis of Childhood Acute Leukemia Cells. Mol Cell Proteomics. 2016;15:1246-61 pubmed publisher
  6. Tookman L, Browne A, Connell C, Bridge G, Ingemarsdotter C, Dowson S, et al. RAD51 and BRCA2 Enhance Oncolytic Adenovirus Type 5 Activity in Ovarian Cancer. Mol Cancer Res. 2016;14:44-55 pubmed publisher
  7. Ortega Atienza S, Wong V, Deloughery Z, Luczak M, Zhitkovich A. ATM and KAT5 safeguard replicating chromatin against formaldehyde damage. Nucleic Acids Res. 2016;44:198-209 pubmed publisher
  8. Hartlerode A, Morgan M, Wu Y, Buis J, Ferguson D. Recruitment and activation of the ATM kinase in the absence of DNA-damage sensors. Nat Struct Mol Biol. 2015;22:736-43 pubmed publisher
  9. Clynes D, Jelinska C, Xella B, Ayyub H, Scott C, Mitson M, et al. Suppression of the alternative lengthening of telomere pathway by the chromatin remodelling factor ATRX. Nat Commun. 2015;6:7538 pubmed publisher
  10. Wang J, Chen S, Sun C, Chien T, Chern Y. A central role of TRAX in the ATM-mediated DNA repair. Oncogene. 2016;35:1657-70 pubmed publisher
  11. Petroni M, Sardina F, Heil C, Sahún Roncero M, Colicchia V, Veschi V, et al. The MRN complex is transcriptionally regulated by MYCN during neural cell proliferation to control replication stress. Cell Death Differ. 2016;23:197-206 pubmed publisher
  12. Larsen D, Hari F, Clapperton J, Gwerder M, Gutsche K, Altmeyer M, et al. The NBS1-Treacle complex controls ribosomal RNA transcription in response to DNA damage. Nat Cell Biol. 2014;16:792-803 pubmed publisher
  13. Clynes D, Jelinska C, Xella B, Ayyub H, Taylor S, Mitson M, et al. ATRX dysfunction induces replication defects in primary mouse cells. PLoS ONE. 2014;9:e92915 pubmed publisher
  14. Becker A, Durante M, Taucher Scholz G, Jakob B. ATM alters the otherwise robust chromatin mobility at sites of DNA double-strand breaks (DSBs) in human cells. PLoS ONE. 2014;9:e92640 pubmed publisher
  15. Martin R, Kerr M, Teo M, Jevons S, Koritzinsky M, Wouters B, et al. Post-transcriptional regulation of MRE11 expression in muscle-invasive bladder tumours. Oncotarget. 2014;5:993-1003 pubmed
  16. Schröder Heurich B, Wieland B, Lavin M, Schindler D, Dork T. Protective role of RAD50 on chromatin bridges during abnormal cytokinesis. FASEB J. 2014;28:1331-41 pubmed publisher
  17. Sahlberg S, Gustafsson A, Pendekanti P, Glimelius B, Stenerlow B. The influence of AKT isoforms on radiation sensitivity and DNA repair in colon cancer cell lines. Tumour Biol. 2014;35:3525-34 pubmed publisher
  18. Birkenkamp Demtroder K, Hahn S, Mansilla F, Thorsen K, Maghnouj A, Christensen R, et al. Keratin23 (KRT23) knockdown decreases proliferation and affects the DNA damage response of colon cancer cells. PLoS ONE. 2013;8:e73593 pubmed publisher
  19. Zhang Z, Liu Y, Yin X, Zhan P, Gu Y, Ni X. Loss of BRCA1 expression leads to worse survival in patients with gastric carcinoma. World J Gastroenterol. 2013;19:1968-74 pubmed publisher