This is a Validated Antibody Database (VAD) review about rat Mmp3, based on 18 published articles (read how Labome selects the articles), using Mmp3 antibody in all methods. It is aimed to help Labome visitors find the most suited Mmp3 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Knockout validation
Abcam
domestic rabbit monoclonal (EP1186Y)
  • western blot knockout validation; mouse; 1:200; loading ...; fig 2a
  • immunohistochemistry; mouse; 1:200; loading ...; fig 1e
Abcam Mmp3 antibody (Abcam, Ab52915) was used in western blot knockout validation on mouse samples at 1:200 (fig 2a) and in immunohistochemistry on mouse samples at 1:200 (fig 1e). Int J Mol Sci (2016) ncbi
Abcam
domestic rabbit monoclonal (EP1186Y)
  • immunohistochemistry; mouse; 1:100; loading ...; fig 7b
Abcam Mmp3 antibody (Abcam, ab52915) was used in immunohistochemistry on mouse samples at 1:100 (fig 7b). Cells (2021) ncbi
domestic rabbit monoclonal (EP1186Y)
  • western blot; mouse; 1:10,000; loading ...; fig 4b
Abcam Mmp3 antibody (Abcam, ab52915) was used in western blot on mouse samples at 1:10,000 (fig 4b). Int J Mol Sci (2021) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig 3b
Abcam Mmp3 antibody (Abcam, ab53015) was used in western blot on human samples at 1:1000 (fig 3b). Arthritis Res Ther (2020) ncbi
domestic rabbit monoclonal (EP1186Y)
  • western blot; mouse; fig 1d
Abcam Mmp3 antibody (Abcam, EP1186Y, ab52915) was used in western blot on mouse samples (fig 1d). Cancers (Basel) (2020) ncbi
domestic rabbit monoclonal (EP1186Y)
  • western blot; mouse; 1:1000; fig 4d
Abcam Mmp3 antibody (Abcam, ab52915) was used in western blot on mouse samples at 1:1000 (fig 4d). elife (2020) ncbi
domestic rabbit monoclonal (EP1186Y)
  • western blot; rat; 1:1000; loading ...; fig 6a
Abcam Mmp3 antibody (Abcam, ab52915) was used in western blot on rat samples at 1:1000 (fig 6a). Aging (Albany NY) (2020) ncbi
domestic rabbit monoclonal (EP1186Y)
  • western blot; human; loading ...; fig 5e
Abcam Mmp3 antibody (Abcam, ab52915) was used in western blot on human samples (fig 5e). Br J Cancer (2019) ncbi
domestic rabbit monoclonal (EP1186Y)
  • immunohistochemistry - paraffin section; mouse; fig 5c
Abcam Mmp3 antibody (Abcam, ab52915) was used in immunohistochemistry - paraffin section on mouse samples (fig 5c). Br J Pharmacol (2018) ncbi
domestic rabbit monoclonal (EP1186Y)
  • western blot; human; loading ...; fig 3a
In order to report that hypoxia alters collagen and matrix metalloproteinase expression in human patients with keratoconus, Abcam Mmp3 antibody (Abcam, ab52915) was used in western blot on human samples (fig 3a). PLoS ONE (2017) ncbi
domestic rabbit monoclonal (EP1186Y)
  • western blot; mouse; loading ...; fig 4g
In order to demonstrate that inhibition of bromodomain and extra-terminal proteins suppresses chondrocyte differentiation and restrains bone growth, Abcam Mmp3 antibody (Abcam, ab52915) was used in western blot on mouse samples (fig 4g). J Biol Chem (2016) ncbi
domestic rabbit monoclonal (EP1186Y)
  • western blot knockout validation; mouse; 1:200; loading ...; fig 2a
  • immunohistochemistry; mouse; 1:200; loading ...; fig 1e
Abcam Mmp3 antibody (Abcam, Ab52915) was used in western blot knockout validation on mouse samples at 1:200 (fig 2a) and in immunohistochemistry on mouse samples at 1:200 (fig 1e). Int J Mol Sci (2016) ncbi
domestic rabbit monoclonal (EP1186Y)
  • western blot; human; 1:1000; loading ...; fig s2
In order to elucidate the relationship between protease prolyl endopeptidase and neural cell adhesion molecule, Abcam Mmp3 antibody (Abcam, ab52915) was used in western blot on human samples at 1:1000 (fig s2). J Cell Sci (2016) ncbi
domestic rabbit monoclonal (EP1186Y)
  • western blot; human; 1:200; fig 5c
Abcam Mmp3 antibody (Abcam, ab52915) was used in western blot on human samples at 1:200 (fig 5c). Arthritis Res Ther (2016) ncbi
domestic rabbit monoclonal (EP1186Y)
  • western blot; mouse; 1:1000; loading ...; fig 6h
Abcam Mmp3 antibody (Abcam, ab52915) was used in western blot on mouse samples at 1:1000 (fig 6h). Nat Commun (2016) ncbi
domestic rabbit monoclonal (EP1186Y)
  • western blot; human; 1:1000; fig 7
Abcam Mmp3 antibody (Abcam, ab52915) was used in western blot on human samples at 1:1000 (fig 7). J Cell Mol Med (2016) ncbi
domestic rabbit monoclonal (EP1186Y)
  • ELISA; human; fig s2g
Abcam Mmp3 antibody (Abcam, ab52915) was used in ELISA on human samples (fig s2g). Arthritis Res Ther (2015) ncbi
domestic rabbit monoclonal (EP1186Y)
  • immunohistochemistry - paraffin section; mouse; 1:300
  • western blot; mouse
Abcam Mmp3 antibody (Abcam, ab52915) was used in immunohistochemistry - paraffin section on mouse samples at 1:300 and in western blot on mouse samples . PLoS ONE (2015) ncbi
Santa Cruz Biotechnology
mouse monoclonal (1B4)
  • western blot; human; 1:1000; loading ...; fig 3f
  • immunohistochemistry - paraffin section; mouse; 1:1000; loading ...; fig 4f
Santa Cruz Biotechnology Mmp3 antibody (Santa Cruz Biotechnology, sc-21732) was used in western blot on human samples at 1:1000 (fig 3f) and in immunohistochemistry - paraffin section on mouse samples at 1:1000 (fig 4f). Int J Mol Med (2021) ncbi
Articles Reviewed
  1. Kang C, Li W, Yu K, Li X, Huang R, Ke P, et al. Long non‑coding RNA AL355711 promotes smooth muscle cell migration through the ABCG1/MMP3 pathway. Int J Mol Med. 2021;48: pubmed publisher
  2. Sebastian A, McCool J, Hum N, Murugesh D, Wilson S, Christiansen B, et al. Single-Cell RNA-Seq Reveals Transcriptomic Heterogeneity and Post-Traumatic Osteoarthritis-Associated Early Molecular Changes in Mouse Articular Chondrocytes. Cells. 2021;10: pubmed publisher
  3. Choi M, Jo J, Lee M, Park J, Park Y. Intra-Articular Administration of Cramp into Mouse Knee Joint Exacerbates Experimental Osteoarthritis Progression. Int J Mol Sci. 2021;22: pubmed publisher
  4. Xu J, Jiang C, Cai Y, Guo Y, Wang X, Zhang J, et al. Intervening upregulated SLC7A5 could mitigate inflammatory mediator by mTOR-P70S6K signal in rheumatoid arthritis synoviocytes. Arthritis Res Ther. 2020;22:200 pubmed publisher
  5. Okusha Y, Eguchi T, Tran M, Sogawa C, Yoshida K, Itagaki M, et al. Extracellular Vesicles Enriched with Moonlighting Metalloproteinase Are Highly Transmissive, Pro-Tumorigenic, and Trans-Activates Cellular Communication Network Factor (CCN2/CTGF): CRISPR against Cancer. Cancers (Basel). 2020;12: pubmed publisher
  6. Che H, Li J, Li Y, Ma C, Liu H, Qin J, et al. p16 deficiency attenuates intervertebral disc degeneration by adjusting oxidative stress and nucleus pulposus cell cycle. elife. 2020;9: pubmed publisher
  7. Jiang L, Xu K, Li J, Zhou X, Xu L, Wu Z, et al. Nesfatin-1 suppresses interleukin-1β-induced inflammation, apoptosis, and cartilage matrix destruction in chondrocytes and ameliorates osteoarthritis in rats. Aging (Albany NY). 2020;12:1760-1777 pubmed publisher
  8. Chen Q, Yang C, Chen L, Zhang J, Ge W, Yuan H, et al. YY1 targets tubulin polymerisation-promoting protein to inhibit migration, invasion and angiogenesis in pancreatic cancer via p38/MAPK and PI3K/AKT pathways. Br J Cancer. 2019;121:912-921 pubmed publisher
  9. Kang L, Kwon E, Lee K, Cho C, Lee J, Ryu Y, et al. 3'-Sialyllactose as an inhibitor of p65 phosphorylation ameliorates the progression of experimental rheumatoid arthritis. Br J Pharmacol. 2018;175:4295-4309 pubmed publisher
  10. McKay T, Hjortdal J, Priyadarsini S, Karamichos D. Acute hypoxia influences collagen and matrix metalloproteinase expression by human keratoconus cells in vitro. PLoS ONE. 2017;12:e0176017 pubmed publisher
  11. Niu N, Shao R, Yan G, Zou W. Bromodomain and Extra-terminal (BET) Protein Inhibitors Suppress Chondrocyte Differentiation and Restrain Bone Growth. J Biol Chem. 2016;291:26647-26657 pubmed publisher
  12. Van Hove I, Lefevere E, De Groef L, Sergeys J, Salinas Navarro M, Libert C, et al. MMP-3 Deficiency Alleviates Endotoxin-Induced Acute Inflammation in the Posterior Eye Segment. Int J Mol Sci. 2016;17: pubmed
  13. Jaako K, Waniek A, Parik K, Klimaviciusa L, Aonurm Helm A, Noortoots A, et al. Prolyl endopeptidase is involved in the degradation of neural cell adhesion molecules in vitro. J Cell Sci. 2016;129:3792-3802 pubmed
  14. Müller S, Acevedo L, Wang X, Karim M, Matta A, Mehrkens A, et al. Notochordal cell conditioned medium (NCCM) regenerates end-stage human osteoarthritic articular chondrocytes and promotes a healthy phenotype. Arthritis Res Ther. 2016;18:125 pubmed publisher
  15. Li C, Zhen G, Chai Y, Xie L, Crane J, Farber E, et al. RhoA determines lineage fate of mesenchymal stem cells by modulating CTGF-VEGF complex in extracellular matrix. Nat Commun. 2016;7:11455 pubmed publisher
  16. Zhao L, Li S, Gan L, Li C, Qiu Z, Feng Y, et al. Paired box 5 is a frequently methylated lung cancer tumour suppressor gene interfering β-catenin signalling and GADD45G expression. J Cell Mol Med. 2016;20:842-54 pubmed publisher
  17. Lowin T, Apitz M, Anders S, Straub R. Anti-inflammatory effects of N-acylethanolamines in rheumatoid arthritis synovial cells are mediated by TRPV1 and TRPA1 in a COX-2 dependent manner. Arthritis Res Ther. 2015;17:321 pubmed publisher
  18. Jakobs C, Perner S, Hornung V. AIM2 Drives Joint Inflammation in a Self-DNA Triggered Model of Chronic Polyarthritis. PLoS ONE. 2015;10:e0131702 pubmed publisher