This is a Validated Antibody Database (VAD) review about rat Me2, based on 3 published articles (read how Labome selects the articles), using Me2 antibody in all methods. It is aimed to help Labome visitors find the most suited Me2 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Knockout validation
Abcam
domestic rabbit monoclonal (EP7217)
  • immunohistochemistry - paraffin section; human; 1:75; loading ...; fig 1a
  • western blot; human; 1:2000; loading ...; fig s1c
  • western blot knockout validation; mouse; 1:2000; loading ...; fig s1b
Abcam Me2 antibody (Abcam, 139686) was used in immunohistochemistry - paraffin section on human samples at 1:75 (fig 1a), in western blot on human samples at 1:2000 (fig s1c) and in western blot knockout validation on mouse samples at 1:2000 (fig s1b). Chin J Cancer Res (2021) ncbi
Abcam
domestic rabbit monoclonal (EP7217)
  • immunohistochemistry - paraffin section; human; 1:75; loading ...; fig 1a
  • western blot; human; 1:2000; loading ...; fig s1c
  • western blot knockout validation; mouse; 1:2000; loading ...; fig s1b
Abcam Me2 antibody (Abcam, 139686) was used in immunohistochemistry - paraffin section on human samples at 1:75 (fig 1a), in western blot on human samples at 1:2000 (fig s1c) and in western blot knockout validation on mouse samples at 1:2000 (fig s1b). Chin J Cancer Res (2021) ncbi
domestic rabbit monoclonal (EP7217)
  • western blot; human; loading ...; fig 2b
Abcam Me2 antibody (Abcam, ab139686) was used in western blot on human samples (fig 2b). Nature (2017) ncbi
domestic rabbit monoclonal (EP7217)
  • western blot; mouse; 1:1000; loading ...; fig s9a
Abcam Me2 antibody (Abcam, ab139686) was used in western blot on mouse samples at 1:1000 (fig s9a). Nat Chem Biol (2016) ncbi
Articles Reviewed
  1. You D, Du D, Zhao X, Li X, Ying M, Hu X. Mitochondrial malic enzyme 2 promotes breast cancer metastasis via stabilizing HIF-1α under hypoxia. Chin J Cancer Res. 2021;33:308-322 pubmed publisher
  2. Dey P, Baddour J, Muller F, Wu C, Wang H, Liao W, et al. Genomic deletion of malic enzyme 2 confers collateral lethality in pancreatic cancer. Nature. 2017;542:119-123 pubmed publisher
  3. Liu L, Shah S, Fan J, Park J, Wellen K, Rabinowitz J. Malic enzyme tracers reveal hypoxia-induced switch in adipocyte NADPH pathway usage. Nat Chem Biol. 2016;12:345-52 pubmed publisher