This is a Validated Antibody Database (VAD) review about rat Mcm2, based on 20 published articles (read how Labome selects the articles), using Mcm2 antibody in all methods. It is aimed to help Labome visitors find the most suited Mcm2 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Abcam
domestic rabbit monoclonal (EPR4120)
  • immunohistochemistry; mouse; 1:5000; loading ...; fig 5a
Abcam Mcm2 antibody (Abcam, ab108935) was used in immunohistochemistry on mouse samples at 1:5000 (fig 5a). elife (2021) ncbi
domestic rabbit monoclonal (EP4120)
  • western blot; human; loading ...; fig 2d
Abcam Mcm2 antibody (Abcam, ab109133) was used in western blot on human samples (fig 2d). Nature (2019) ncbi
domestic rabbit monoclonal (EPR4170(2))
  • western blot; human; loading ...; fig 2a
In order to determine specific residues on four MCM helicase subunits that show hyperphosphorylation upon RIF1 depletion, Abcam Mcm2 antibody (Abcam, ab133243) was used in western blot on human samples (fig 2a). EMBO Rep (2017) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:2000; loading ...; fig 1a
Abcam Mcm2 antibody (Abcam, ab70371) was used in western blot on human samples at 1:2000 (fig 1a). Cancer Cell Int (2016) ncbi
domestic rabbit monoclonal (EPR4120)
  • western blot; human; 1:1000; loading ...; fig 1a
Abcam Mcm2 antibody (Abcam, ab108935) was used in western blot on human samples at 1:1000 (fig 1a). Cancer Cell Int (2016) ncbi
domestic rabbit monoclonal (EPR4120)
  • western blot; mouse; fig 1d
Abcam Mcm2 antibody (Abcam, ab108935) was used in western blot on mouse samples (fig 1d). PLoS Genet (2016) ncbi
Santa Cruz Biotechnology
mouse monoclonal (E-8)
  • immunohistochemistry - paraffin section; human; loading ...; fig 2a
Santa Cruz Biotechnology Mcm2 antibody (SantaCruz, sc-373702) was used in immunohistochemistry - paraffin section on human samples (fig 2a). Mol Med Rep (2016) ncbi
Cell Signaling Technology
domestic rabbit polyclonal
  • immunohistochemistry; mouse; loading ...; fig s22d
  • western blot; mouse; loading ...; fig s22c
Cell Signaling Technology Mcm2 antibody (Cell Signaling, 4007S) was used in immunohistochemistry on mouse samples (fig s22d) and in western blot on mouse samples (fig s22c). Science (2019) ncbi
domestic rabbit monoclonal (D7G11)
  • western blot; human; loading ...; fig s2a
In order to research the association between phosphorylated SIRT1 with replication origins and its effect on genomic stability, Cell Signaling Technology Mcm2 antibody (Cell Signaling, 3619) was used in western blot on human samples (fig s2a). Nucleic Acids Res (2017) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:500; loading ...; fig 1d
Cell Signaling Technology Mcm2 antibody (Cell Signaling, 4007) was used in western blot on human samples at 1:500 (fig 1d). Am J Pathol (2017) ncbi
domestic rabbit monoclonal (D7G11)
  • western blot; human; loading ...; fig 6e
Cell Signaling Technology Mcm2 antibody (Cell Signaling, 3619) was used in western blot on human samples (fig 6e). Oncotarget (2016) ncbi
domestic rabbit monoclonal (D7G11)
  • western blot; mouse; loading ...; fig s7e
In order to research the roles of HSF1 and mTORC1 in proteotoxic stress and cell growth, Cell Signaling Technology Mcm2 antibody (Cell Signaling, 3619) was used in western blot on mouse samples (fig s7e). Nat Cell Biol (2016) ncbi
domestic rabbit monoclonal (D7G11)
  • western blot; human; fig 7
Cell Signaling Technology Mcm2 antibody (Cell Signaling Technology, D7G11) was used in western blot on human samples (fig 7). PLoS ONE (2015) ncbi
domestic rabbit monoclonal (D7G11)
  • western blot; human; 1:1000; loading ...; fig 4a
Cell Signaling Technology Mcm2 antibody (Cell Signaling, CST-3619) was used in western blot on human samples at 1:1000 (fig 4a). Cell Death Dis (2014) ncbi
domestic rabbit monoclonal (D7G11)
  • flow cytometry; mouse
Cell Signaling Technology Mcm2 antibody (Cell Signaling Technologies, D7G11) was used in flow cytometry on mouse samples . Front Cell Neurosci (2014) ncbi
domestic rabbit monoclonal (D7G11)
  • immunohistochemistry - paraffin section; mouse; 1:400
Cell Signaling Technology Mcm2 antibody (Cell Signaling Technology, 3619) was used in immunohistochemistry - paraffin section on mouse samples at 1:400. Evid Based Complement Alternat Med (2012) ncbi
BD Biosciences
mouse monoclonal (46/BM28)
  • flow cytometry; human; 1:200; loading ...; fig 2d
BD Biosciences Mcm2 antibody (BD Biosciences, 610700) was used in flow cytometry on human samples at 1:200 (fig 2d). Nat Commun (2021) ncbi
mouse monoclonal (46/BM28)
  • immunohistochemistry - frozen section; mouse; 1:500; loading ...; fig 2a
BD Biosciences Mcm2 antibody (BD Bioscience, 610700) was used in immunohistochemistry - frozen section on mouse samples at 1:500 (fig 2a). Proc Natl Acad Sci U S A (2019) ncbi
mouse monoclonal (46/BM28)
  • flow cytometry; human; 1:200; loading ...; fig s2a
  • western blot; human; 1:10,000; loading ...; fig s2f
BD Biosciences Mcm2 antibody (BD Biosciences, 610700) was used in flow cytometry on human samples at 1:200 (fig s2a) and in western blot on human samples at 1:10,000 (fig s2f). elife (2017) ncbi
mouse monoclonal (46/BM28)
  • western blot; human; fig s1
BD Biosciences Mcm2 antibody (BD Transduction Lab, 610700) was used in western blot on human samples (fig s1). Nucleic Acids Res (2015) ncbi
mouse monoclonal (46/BM28)
  • immunohistochemistry - free floating section; mouse; 1:500; fig s3
BD Biosciences Mcm2 antibody (BD Biosciences, 610700) was used in immunohistochemistry - free floating section on mouse samples at 1:500 (fig s3). Nat Med (2015) ncbi
Articles Reviewed
  1. Zewdu R, Mehrabad E, Ingram K, Fang P, Gillis K, Camolotto S, et al. An NKX2-1/ERK/WNT feedback loop modulates gastric identity and response to targeted therapy in lung adenocarcinoma. elife. 2021;10: pubmed publisher
  2. Baxley R, Leung W, Schmit M, Matson J, Yin L, Oram M, et al. Bi-allelic MCM10 variants associated with immune dysfunction and cardiomyopathy cause telomere shortening. Nat Commun. 2021;12:1626 pubmed publisher
  3. Wang C, Vegna S, Jin H, Benedict B, Lieftink C, Ramirez C, et al. Inducing and exploiting vulnerabilities for the treatment of liver cancer. Nature. 2019;: pubmed publisher
  4. Nieto González J, Gómez Sánchez L, Mavillard F, Linares Clemente P, Rivero M, Valenzuela Villatoro M, et al. Loss of postnatal quiescence of neural stem cells through mTOR activation upon genetic removal of cysteine string protein-α. Proc Natl Acad Sci U S A. 2019;116:8000-8009 pubmed publisher
  5. Nicetto D, Donahue G, Jain T, Peng T, Sidoli S, Sheng L, et al. H3K9me3-heterochromatin loss at protein-coding genes enables developmental lineage specification. Science. 2019;363:294-297 pubmed publisher
  6. Matson J, Dumitru R, Coryell P, Baxley R, Chen W, Twaroski K, et al. Rapid DNA replication origin licensing protects stem cell pluripotency. elife. 2017;6: pubmed publisher
  7. Utani K, Fu H, Jang S, Marks A, Smith O, Zhang Y, et al. Phosphorylated SIRT1 associates with replication origins to prevent excess replication initiation and preserve genomic stability. Nucleic Acids Res. 2017;45:7807-7824 pubmed publisher
  8. Hiraga S, Ly T, Garzón J, Horejsi Z, Ohkubo Y, Endo A, et al. Human RIF1 and protein phosphatase 1 stimulate DNA replication origin licensing but suppress origin activation. EMBO Rep. 2017;18:403-419 pubmed publisher
  9. Hölzer K, Drucker E, Roessler S, Dauch D, Heinzmann F, Waldburger N, et al. Proteomic Analysis Reveals GMP Synthetase as p53 Repression Target in Liver Cancer. Am J Pathol. 2017;187:228-235 pubmed publisher
  10. Erbayraktar Z, Alural B, Erbayraktar R, Erkan E. Cell division cycle 7-kinase inhibitor PHA-767491 hydrochloride suppresses glioblastoma growth and invasiveness. Cancer Cell Int. 2016;16:88 pubmed publisher
  11. Liu Z, Yang Z, Jiang S, Zou Q, Yuan Y, Li J, et al. MCM2 and TIP30 are prognostic markers in squamous cell/adenosquamous carcinoma and adenocarcinoma of the gallbladder. Mol Med Rep. 2016;14:4581-4592 pubmed publisher
  12. Hong S, Eun J, Choi S, Shen Q, Choi W, Han J, et al. Epigenetic reader BRD4 inhibition as a therapeutic strategy to suppress E2F2-cell cycle regulation circuit in liver cancer. Oncotarget. 2016;7:32628-40 pubmed publisher
  13. Su K, Cao J, Tang Z, Dai S, He Y, Sampson S, et al. HSF1 critically attunes proteotoxic stress sensing by mTORC1 to combat stress and promote growth. Nat Cell Biol. 2016;18:527-39 pubmed publisher
  14. Bai G, Smolka M, Schimenti J. Chronic DNA Replication Stress Reduces Replicative Lifespan of Cells by TRP53-Dependent, microRNA-Assisted MCM2-7 Downregulation. PLoS Genet. 2016;12:e1005787 pubmed publisher
  15. Graindorge D, Martineau S, Machon C, Arnoux P, Guitton J, Francesconi S, et al. Singlet Oxygen-Mediated Oxidation during UVA Radiation Alters the Dynamic of Genomic DNA Replication. PLoS ONE. 2015;10:e0140645 pubmed publisher
  16. Rivera C, Saavedra F, Alvarez F, Díaz Celis C, Ugalde V, Li J, et al. Methylation of histone H3 lysine 9 occurs during translation. Nucleic Acids Res. 2015;43:9097-106 pubmed publisher
  17. Smith L, He Y, Park J, Bieri G, Snethlage C, Lin K, et al. β2-microglobulin is a systemic pro-aging factor that impairs cognitive function and neurogenesis. Nat Med. 2015;21:932-7 pubmed publisher
  18. Cao J, Lu Y, Qi J, An G, Mao Z, Jia H, et al. MiR-630 inhibits proliferation by targeting CDC7 kinase, but maintains the apoptotic balance by targeting multiple modulators in human lung cancer A549 cells. Cell Death Dis. 2014;5:e1426 pubmed publisher
  19. Marshall G, Deleyrolle L, Reynolds B, Steindler D, Laywell E. Microglia from neurogenic and non-neurogenic regions display differential proliferative potential and neuroblast support. Front Cell Neurosci. 2014;8:180 pubmed publisher
  20. Kawabata K, Tung N, Shoyama Y, Sugie S, Mori T, Tanaka T. Dietary Crocin Inhibits Colitis and Colitis-Associated Colorectal Carcinogenesis in Male ICR Mice. Evid Based Complement Alternat Med. 2012;2012:820415 pubmed publisher