This is a Validated Antibody Database (VAD) review about rat Mad2l1, based on 16 published articles (read how Labome selects the articles), using Mad2l1 antibody in all methods. It is aimed to help Labome visitors find the most suited Mad2l1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Mad2l1 synonym: mitotic spindle assembly checkpoint protein MAD2A; MAD2 (mitotic arrest deficient, homolog)-like 1; MAD2 mitotic arrest deficient-like 1

Santa Cruz Biotechnology
mouse monoclonal (C-9)
  • western blot; human; loading ...; fig 3c
Santa Cruz Biotechnology Mad2l1 antibody (Santa Cruz, C-9) was used in western blot on human samples (fig 3c). Cell Death Dis (2016) ncbi
mouse monoclonal (107-276-3)
  • immunocytochemistry; human; 1:75; fig 2
Santa Cruz Biotechnology Mad2l1 antibody (santa Cruz, sc-65492) was used in immunocytochemistry on human samples at 1:75 (fig 2). Oncotarget (2016) ncbi
mouse monoclonal (107-276-3)
  • immunocytochemistry; human; fig 2
In order to characterize the role of BAG3-HSPB8 in mitosis, Santa Cruz Biotechnology Mad2l1 antibody (Santa Cruz Biotechnology, sc-65492) was used in immunocytochemistry on human samples (fig 2). PLoS Genet (2015) ncbi
Cell Signaling Technology
rabbit monoclonal (D8A7)
  • western blot; mouse; loading ...; fig s3b
Cell Signaling Technology Mad2l1 antibody (Cell Signaling, 4636) was used in western blot on mouse samples (fig s3b). Oncogene (2017) ncbi
rabbit monoclonal (D8A7)
  • western blot; human; fig 5
Cell Signaling Technology Mad2l1 antibody (Cell signaling, 4636) was used in western blot on human samples (fig 5). J Biol Chem (2016) ncbi
rabbit monoclonal (D8A7)
  • western blot; human; loading ...; fig 4a
Cell Signaling Technology Mad2l1 antibody (Cell Signaling Technology, 4636) was used in western blot on human samples (fig 4a). PLoS ONE (2015) ncbi
rabbit monoclonal (D8A7)
  • western blot; human
Cell Signaling Technology Mad2l1 antibody (Cell Signaling Technology, D8A7) was used in western blot on human samples . Nat Commun (2014) ncbi
BD Biosciences
mouse monoclonal (48/MAD2)
  • western blot; mouse; loading ...; fig 1d
BD Biosciences Mad2l1 antibody (BD Biosciences, 48) was used in western blot on mouse samples (fig 1d). Cell Rep (2017) ncbi
mouse monoclonal (48/MAD2)
  • immunoprecipitation; mouse; 1:1000; fig 6
BD Biosciences Mad2l1 antibody (BD Transduction, 610679) was used in immunoprecipitation on mouse samples at 1:1000 (fig 6). elife (2016) ncbi
mouse monoclonal (48/MAD2)
  • immunohistochemistry; mouse; 1:2000; loading ...; fig 1c
  • western blot; mouse; 1:2000; loading ...; fig s1d
BD Biosciences Mad2l1 antibody (BD, 610679) was used in immunohistochemistry on mouse samples at 1:2000 (fig 1c) and in western blot on mouse samples at 1:2000 (fig s1d). Cell Rep (2016) ncbi
mouse monoclonal (48/MAD2)
  • western blot; human; fig s4b
BD Biosciences Mad2l1 antibody (BD Transduction Laboratorie, 610679) was used in western blot on human samples (fig s4b). Proc Natl Acad Sci U S A (2016) ncbi
mouse monoclonal (48/MAD2)
  • other; human; loading ...; fig st1
In order to use size exclusion chromatography-microsphere-based affinity proteomics to study clinical samples obtained from pediatric acute leukemia patients, BD Biosciences Mad2l1 antibody (BD, 48) was used in other on human samples (fig st1). Mol Cell Proteomics (2016) ncbi
mouse monoclonal (48/MAD2)
  • western blot; human; fig 1
BD Biosciences Mad2l1 antibody (BD Biosciences, 610678) was used in western blot on human samples (fig 1). Cell Cycle (2015) ncbi
mouse monoclonal (48/MAD2)
  • western blot; human; fig s4
BD Biosciences Mad2l1 antibody (BD Biosciences, 610678) was used in western blot on human samples (fig s4). Oncogene (2015) ncbi
mouse monoclonal (48/MAD2)
  • immunoprecipitation; human; 1:500; fig 4
BD Biosciences Mad2l1 antibody (BD transduction laboratories, 610679) was used in immunoprecipitation on human samples at 1:500 (fig 4). Nature (2015) ncbi
mouse monoclonal (48/MAD2)
  • western blot; human
BD Biosciences Mad2l1 antibody (BD biosciences, 610678) was used in western blot on human samples . Cell Cycle (2014) ncbi
Articles Reviewed
  1. Marks D, Thomas R, Chin Y, Shah R, Khoo C, Benezra R. Mad2 Overexpression Uncovers a Critical Role for TRIP13 in Mitotic Exit. Cell Rep. 2017;19:1832-1845 pubmed publisher
  2. Dawar S, Lim Y, Puccini J, White M, Thomas P, Bouchier Hayes L, et al. Caspase-2-mediated cell death is required for deleting aneuploid cells. Oncogene. 2017;36:2704-2714 pubmed publisher
  3. Weaver R, Limzerwala J, Naylor R, Jeganathan K, Baker D, van Deursen J. BubR1 alterations that reinforce mitotic surveillance act against aneuploidy and cancer. elife. 2016;5: pubmed publisher
  4. Zhang X, Ling Y, Guo Y, Bai Y, Shi X, Gong F, et al. Mps1 kinase regulates tumor cell viability via its novel role in mitochondria. Cell Death Dis. 2016;7:e2292 pubmed publisher
  5. Rowald K, Mantovan M, Passos J, Buccitelli C, Mardin B, Korbel J, et al. Negative Selection and Chromosome Instability Induced by Mad2 Overexpression Delay Breast Cancer but Facilitate Oncogene-Independent Outgrowth. Cell Rep. 2016;15:2679-91 pubmed publisher
  6. Chen X, Stauffer S, Chen Y, Dong J. Ajuba Phosphorylation by CDK1 Promotes Cell Proliferation and Tumorigenesis. J Biol Chem. 2016;291:14761-72 pubmed publisher
  7. Tambe M, Pruikkonen S, Mäki Jouppila J, Chen P, Elgaaen B, Straume A, et al. Novel Mad2-targeting miR-493-3p controls mitotic fidelity and cancer cells' sensitivity to paclitaxel. Oncotarget. 2016;7:12267-85 pubmed publisher
  8. Craney A, Kelly A, Jia L, Fedrigo I, Yu H, Rape M. Control of APC/C-dependent ubiquitin chain elongation by reversible phosphorylation. Proc Natl Acad Sci U S A. 2016;113:1540-5 pubmed publisher
  9. Kanderová V, Kuzilkova D, Stuchly J, Vaskova M, Brdicka T, Fiser K, et al. High-resolution Antibody Array Analysis of Childhood Acute Leukemia Cells. Mol Cell Proteomics. 2016;15:1246-61 pubmed publisher
  10. Fuchs M, Luthold C, Guilbert S, Varlet A, Lambert H, Jetté A, et al. A Role for the Chaperone Complex BAG3-HSPB8 in Actin Dynamics, Spindle Orientation and Proper Chromosome Segregation during Mitosis. PLoS Genet. 2015;11:e1005582 pubmed publisher
  11. Wang Z, Katsaros D, Shen Y, Fu Y, Canuto E, Benedetto C, et al. Biological and Clinical Significance of MAD2L1 and BUB1, Genes Frequently Appearing in Expression Signatures for Breast Cancer Prognosis. PLoS ONE. 2015;10:e0136246 pubmed publisher
  12. Chen D, Ito S, Yuan H, Hyodo T, Kadomatsu K, Hamaguchi M, et al. EML4 promotes the loading of NUDC to the spindle for mitotic progression. Cell Cycle. 2015;14:1529-39 pubmed publisher
  13. Kanu N, Grönroos E, Martinez P, Burrell R, Yi Goh X, Bartkova J, et al. SETD2 loss-of-function promotes renal cancer branched evolution through replication stress and impaired DNA repair. Oncogene. 2015;34:5699-708 pubmed publisher
  14. Brownlow N, Pike T, Zicha D, Collinson L, Parker P. Mitotic catenation is monitored and resolved by a PKCε-regulated pathway. Nat Commun. 2014;5:5685 pubmed publisher
  15. Izawa D, Pines J. The mitotic checkpoint complex binds a second CDC20 to inhibit active APC/C. Nature. 2015;517:631-4 pubmed publisher
  16. Singh A, Zapata M, Choi Y, Yoon S. GSI promotes vincristine-induced apoptosis by enhancing multi-polar spindle formation. Cell Cycle. 2014;13:157-66 pubmed publisher