This is a Validated Antibody Database (VAD) review about rat MT SP1, based on 2 published articles (read how Labome selects the articles), using MT SP1 antibody in all methods. It is aimed to help Labome visitors find the most suited MT SP1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
MT SP1 synonym: MT-SP1; suppressor of tumorigenicity 14 protein; matriptase; membrane-type serine protease; suppression of tumorigenicity 14 (colon carcinoma); suppression of tumorigenicity 14 (colon carcinoma, matriptase, epithin)

Abcam
rabbit polyclonal
  • immunocytochemistry; human; 1:500; fig 1
  • western blot; human; 1:1000; fig 2
Abcam MT SP1 antibody (abcam, ab28266) was used in immunocytochemistry on human samples at 1:500 (fig 1) and in western blot on human samples at 1:1000 (fig 2). Mol Med Rep (2016) ncbi
EMD Millipore
rabbit polyclonal
  • immunocytochemistry; human; loading ...; fig 2b
  • western blot; human; loading ...; fig 6c
In order to test if HAI-2, matriptase, EpCAM, and claudin-7 are functionally linked in the intestine, EMD Millipore MT SP1 antibody (EMD Biosciences, IM1014) was used in immunocytochemistry on human samples (fig 2b) and in western blot on human samples (fig 6c). J Clin Invest (2017) ncbi
Articles Reviewed
  1. Wu C, Feng X, Lu M, Morimura S, Udey M. Matriptase-mediated cleavage of EpCAM destabilizes claudins and dysregulates intestinal epithelial homeostasis. J Clin Invest. 2017;127:623-634 pubmed publisher
  2. Sun P, Jiang Z, Chen X, Xue L, Mao X, Ruan G, et al. Decreasing the ratio of matriptase/HAI?1 by downregulation of matriptase as a potential adjuvant therapy in ovarian cancer. Mol Med Rep. 2016;14:1465-74 pubmed publisher