This is a Validated Antibody Database (VAD) review about rat Lgr5, based on 6 published articles (read how Labome selects the articles), using Lgr5 antibody in all methods. It is aimed to help Labome visitors find the most suited Lgr5 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Lgr5 synonym: Gpr49; leucine-rich repeat-containing G-protein coupled receptor 5; G protein-coupled receptor 49

Abcam
rabbit monoclonal (EPR3065Y)
  • immunohistochemistry - paraffin section; human; 1:100; loading ...; fig 1a
Abcam Lgr5 antibody (Abcam, ab75850) was used in immunohistochemistry - paraffin section on human samples at 1:100 (fig 1a). Gastric Cancer (2018) ncbi
rabbit monoclonal (EPR3065Y)
  • flow cytometry; mouse; loading ...; fig st2
In order to identify a role for Sca-1 in mouse gastric cancer, Abcam Lgr5 antibody (Abcam, ab75850) was used in flow cytometry on mouse samples (fig st2). Stem Cells (2016) ncbi
rabbit monoclonal (EPR3065Y)
  • immunohistochemistry - paraffin section; human; fig s12
  • immunohistochemistry - paraffin section; mouse; fig 1
  • western blot; mouse; fig 3
Abcam Lgr5 antibody (Abcam, EPR3065Y) was used in immunohistochemistry - paraffin section on human samples (fig s12), in immunohistochemistry - paraffin section on mouse samples (fig 1) and in western blot on mouse samples (fig 3). Sci Rep (2015) ncbi
rabbit monoclonal (EPR3065Y)
  • western blot; human; loading ...; fig 2c
Abcam Lgr5 antibody (Abcam, ab75850) was used in western blot on human samples (fig 2c). Br J Cancer (2015) ncbi
rabbit monoclonal (EPR3065Y)
  • immunohistochemistry - paraffin section; rat; 1:250
Abcam Lgr5 antibody (Abcam, ab75850) was used in immunohistochemistry - paraffin section on rat samples at 1:250. BMC Cancer (2013) ncbi
GeneTex
rabbit monoclonal (EPR3065Y)
  • western blot; human; fig 1
In order to investigate the role of sciellin in colorectal cancer, GeneTex Lgr5 antibody (GeneTex, GTX62071) was used in western blot on human samples (fig 1). Oncotarget (2016) ncbi
Articles Reviewed
  1. Walker R, Poleszczuk J, Mejia J, Lee J, Pimiento J, Malafa M, et al. Toward early detection of Helicobacter pylori-associated gastric cancer. Gastric Cancer. 2018;21:196-203 pubmed publisher
  2. Chou C, Fan C, Lin P, Liao P, Tung J, Hsieh C, et al. Sciellin mediates mesenchymal-to-epithelial transition in colorectal cancer hepatic metastasis. Oncotarget. 2016;7:25742-54 pubmed publisher
  3. Park J, Park J, Park D, Kim D, Kim H. Stem Cells Antigen-1 Enriches for a Cancer Stem Cell-Like Subpopulation in Mouse Gastric Cancer. Stem Cells. 2016;34:1177-87 pubmed publisher
  4. Su X, Yan H, Huang Y, Yun H, Zeng B, Wang E, et al. Expression of FABP4, adipsin and adiponectin in Paneth cells is modulated by gut Lactobacillus. Sci Rep. 2015;5:18588 pubmed publisher
  5. Morgan R, Molnár E, Jones R, Collard T, Lane J, Greenhough A, et al. Nutrient stress alters the glycosylation status of LGR5 resulting in reduced protein stability and membrane localisation in colorectal tumour cells: implications for targeting cancer stem cells. Br J Cancer. 2015;112:714-9 pubmed publisher
  6. Femia A, Dolara P, Salvadori M, Caderni G. Expression of LGR-5, MSI-1 and DCAMKL-1, putative stem cell markers, in the early phases of 1,2-dimethylhydrazine-induced rat colon carcinogenesis: correlation with nuclear ?-catenin. BMC Cancer. 2013;13:48 pubmed publisher