This is a Validated Antibody Database (VAD) review about rat Lgi1, based on 2 published articles (read how Labome selects the articles), using Lgi1 antibody in all methods. It is aimed to help Labome visitors find the most suited Lgi1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Lgi1 synonym: leucine-rich glioma-inactivated protein 1; leucine-rich glioma-inactivated protein 1-like; leucine-rich repeat LGI family, member 1

Abcam
rabbit polyclonal
  • immunohistochemistry; mouse; 1 ug/ml; fig 2c
  • western blot; mouse; 1 ug/ml; fig 2a
  • western blot; human; 1 ug/ml; fig s2d
In order to use mouse models to discover mechanisms that lead to LGI1-related epilepsy, Abcam Lgi1 antibody (Abcam, ab30868) was used in immunohistochemistry on mouse samples at 1 ug/ml (fig 2c), in western blot on mouse samples at 1 ug/ml (fig 2a) and in western blot on human samples at 1 ug/ml (fig s2d). Nat Med (2015) ncbi
rabbit polyclonal
  • immunohistochemistry - paraffin section; mouse
  • western blot; mouse; 1:500
Abcam Lgi1 antibody (Abcam, ab30868) was used in immunohistochemistry - paraffin section on mouse samples and in western blot on mouse samples at 1:500. Brain (2014) ncbi
Articles Reviewed
  1. Yokoi N, Fukata Y, Kase D, Miyazaki T, Jaegle M, Ohkawa T, et al. Chemical corrector treatment ameliorates increased seizure susceptibility in a mouse model of familial epilepsy. Nat Med. 2015;21:19-26 pubmed publisher
  2. Boillot M, Huneau C, Marsan E, Lehongre K, Navarro V, Ishida S, et al. Glutamatergic neuron-targeted loss of LGI1 epilepsy gene results in seizures. Brain. 2014;137:2984-96 pubmed publisher