This is a Validated Antibody Database (VAD) review about rat Lepr, based on 9 published articles (read how Labome selects the articles), using Lepr antibody in all methods. It is aimed to help Labome visitors find the most suited Lepr antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Lepr synonym: leptin receptor; LEP-R; Leptin receptor (fatty); OB receptor; OB-R

Knockout validation
Santa Cruz Biotechnology
mouse monoclonal (B-3)
  • immunohistochemistry knockout validation; mouse; 1:100; fig 1
Santa Cruz Biotechnology Lepr antibody (Santa Cruz Biotechnology, sc8391) was used in immunohistochemistry knockout validation on mouse samples at 1:100 (fig 1). Mol Metab (2014) ncbi
Santa Cruz Biotechnology
mouse monoclonal (B-3)
  • western blot; mouse; 1:1000; loading ...; fig 10
Santa Cruz Biotechnology Lepr antibody (SantaCruz, sc-8391) was used in western blot on mouse samples at 1:1000 (fig 10). Am J Physiol Regul Integr Comp Physiol (2017) ncbi
mouse monoclonal (B-3)
  • western blot; human; fig 2
Santa Cruz Biotechnology Lepr antibody (Santa Cruz Biotechnology, sc-8391) was used in western blot on human samples (fig 2). Arthritis Res Ther (2016) ncbi
mouse monoclonal (B-3)
  • immunoprecipitation; mouse; fig 7
  • western blot; mouse; 1:1000; fig 7
Santa Cruz Biotechnology Lepr antibody (Santa Cruz, sc-8391) was used in immunoprecipitation on mouse samples (fig 7) and in western blot on mouse samples at 1:1000 (fig 7). PLoS Genet (2016) ncbi
mouse monoclonal (B-3)
  • immunohistochemistry; human; 1:25; loading ...; fig 1b
  • western blot; human; 1:500; loading ...; fig 3
Santa Cruz Biotechnology Lepr antibody (Santa Cruz, sc-8391) was used in immunohistochemistry on human samples at 1:25 (fig 1b) and in western blot on human samples at 1:500 (fig 3). PLoS ONE (2015) ncbi
mouse monoclonal (B-3)
  • immunohistochemistry knockout validation; mouse; 1:100; fig 1
Santa Cruz Biotechnology Lepr antibody (Santa Cruz Biotechnology, sc8391) was used in immunohistochemistry knockout validation on mouse samples at 1:100 (fig 1). Mol Metab (2014) ncbi
mouse monoclonal (B-3)
  • immunohistochemistry; human; fig 2
Santa Cruz Biotechnology Lepr antibody (santa cruz, sc-8391) was used in immunohistochemistry on human samples (fig 2). Reprod Sci (2015) ncbi
Abcam
rabbit polyclonal
  • western blot; human; 1:2000; fig 3
Abcam Lepr antibody (abcam, ab5593) was used in western blot on human samples at 1:2000 (fig 3). Cancer Chemother Pharmacol (2016) ncbi
rabbit polyclonal
  • western blot; rat; fig 3
Abcam Lepr antibody (abcam, ab5593) was used in western blot on rat samples (fig 3). Int J Mol Sci (2016) ncbi
rabbit polyclonal
  • immunohistochemistry - paraffin section; human; 1:1000; loading ...; fig 6c
Abcam Lepr antibody (Abcam, ab5593) was used in immunohistochemistry - paraffin section on human samples at 1:1000 (fig 6c). PLoS ONE (2015) ncbi
Articles Reviewed
  1. Yi X, Gao H, Chen D, Tang D, Huang W, Li T, et al. Effects of obesity and exercise on testicular leptin signal transduction and testosterone biosynthesis in male mice. Am J Physiol Regul Integr Comp Physiol. 2017;312:R501-R510 pubmed publisher
  2. Malaise O, Relic B, Charlier E, Zeddou M, Neuville S, Deroyer C, et al. Glucocorticoid-induced leucine zipper (GILZ) is involved in glucocorticoid-induced and mineralocorticoid-induced leptin production by osteoarthritis synovial fibroblasts. Arthritis Res Ther. 2016;18:219 pubmed
  3. Fiedor E, Gregoraszczuk E. The molecular mechanism of action of superactive human leptin antagonist (SHLA) and quadruple leptin mutein Lan-2 on human ovarian epithelial cell lines. Cancer Chemother Pharmacol. 2016;78:611-22 pubmed publisher
  4. Huang Y, Chen C, Tang K, Sheen J, Tiao M, Tain Y, et al. Postnatal High-Fat Diet Increases Liver Steatosis and Apoptosis Threatened by Prenatal Dexamethasone through the Oxidative Effect. Int J Mol Sci. 2016;17:369 pubmed publisher
  5. Guo D, Cui H, Zhang Q, Morgan D, Thedens D, Nishimura D, et al. The BBSome Controls Energy Homeostasis by Mediating the Transport of the Leptin Receptor to the Plasma Membrane. PLoS Genet. 2016;12:e1005890 pubmed publisher
  6. Ramirez H, Liang L, Pastar I, Rosa A, Stojadinovic O, Zwick T, et al. Comparative Genomic, MicroRNA, and Tissue Analyses Reveal Subtle Differences between Non-Diabetic and Diabetic Foot Skin. PLoS ONE. 2015;10:e0137133 pubmed publisher
  7. Choi E, Byeon S, Kim S, Lee H, Kwon H, Ahn H, et al. Implication of Leptin-Signaling Proteins and Epstein-Barr Virus in Gastric Carcinomas. PLoS ONE. 2015;10:e0130839 pubmed publisher
  8. de Lartigue G, Ronveaux C, Raybould H. Deletion of leptin signaling in vagal afferent neurons results in hyperphagia and obesity. Mol Metab. 2014;3:595-607 pubmed publisher
  9. Tsai P, Davis J, Bryant Greenwood G. Systemic and placental leptin and its receptors in pregnancies associated with obesity. Reprod Sci. 2015;22:189-97 pubmed publisher