This is a Validated Antibody Database (VAD) review about rat Lats1, based on 32 published articles (read how Labome selects the articles), using Lats1 antibody in all methods. It is aimed to help Labome visitors find the most suited Lats1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Lats1 synonym: RGD1564085

Cell Signaling Technology
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 1s2a, 1s3a
Cell Signaling Technology Lats1 antibody (Cell Signaling, 9157) was used in western blot on human samples (fig 1s2a, 1s3a). elife (2020) ncbi
domestic rabbit monoclonal (D57D3)
  • western blot; human; loading ...; fig 1s2a
Cell Signaling Technology Lats1 antibody (Cell Signaling, 8654) was used in western blot on human samples (fig 1s2a). elife (2020) ncbi
domestic rabbit monoclonal (D57D3)
  • western blot; mouse; 1:1000; loading ...; fig 7b
Cell Signaling Technology Lats1 antibody (CST, 8654) was used in western blot on mouse samples at 1:1000 (fig 7b). elife (2020) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; human; 1:1000; loading ...; fig s9a
Cell Signaling Technology Lats1 antibody (Cell Signaling, 9157) was used in immunohistochemistry - paraffin section on human samples at 1:1000 (fig s9a). Nat Commun (2020) ncbi
domestic rabbit monoclonal (D57D3)
  • western blot; human; loading ...; fig 2b
Cell Signaling Technology Lats1 antibody (Cell Signaling, 8654) was used in western blot on human samples (fig 2b). Redox Biol (2020) ncbi
domestic rabbit monoclonal (D57D3)
  • western blot; human; loading ...; fig 7c
Cell Signaling Technology Lats1 antibody (Cell Signaling Technology, 8654S) was used in western blot on human samples (fig 7c). elife (2020) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 3b
Cell Signaling Technology Lats1 antibody (Cell Signaling, 9157) was used in western blot on human samples (fig 3b). Biomolecules (2019) ncbi
domestic rabbit monoclonal (D57D3)
  • western blot; human; 1:1000; loading ...; fig 3b, 3j
Cell Signaling Technology Lats1 antibody (CST, 8654) was used in western blot on human samples at 1:1000 (fig 3b, 3j). elife (2019) ncbi
domestic rabbit monoclonal (D57D3)
  • western blot; human; 1:500; loading ...; fig 3a
Cell Signaling Technology Lats1 antibody (Cell Signaling Technology, 8654) was used in western blot on human samples at 1:500 (fig 3a). Cancer Manag Res (2019) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig 5c
Cell Signaling Technology Lats1 antibody (Cell Signaling, 9157) was used in western blot on human samples at 1:1000 (fig 5c). J Cell Sci (2018) ncbi
domestic rabbit monoclonal (D57D3)
  • western blot; human; 1:1000; loading ...; fig 7b
Cell Signaling Technology Lats1 antibody (Cell Signaling, 8654) was used in western blot on human samples at 1:1000 (fig 7b). J Cell Sci (2018) ncbi
domestic rabbit monoclonal (D57D3)
  • western blot; rat; 1:500; loading ...; fig 2a
Cell Signaling Technology Lats1 antibody (Cell Signaling, 8654) was used in western blot on rat samples at 1:500 (fig 2a). Mol Med Rep (2018) ncbi
domestic rabbit polyclonal
  • immunoprecipitation; rat; 1:5000; loading ...; fig 7c
Cell Signaling Technology Lats1 antibody (Cell Signaling Technologies, 9157) was used in immunoprecipitation on rat samples at 1:5000 (fig 7c). J Cell Biol (2018) ncbi
domestic rabbit monoclonal (D57D3)
  • western blot; human; 1:500; fig 3b
Cell Signaling Technology Lats1 antibody (Cell Signaling, 8654S) was used in western blot on human samples at 1:500 (fig 3b). Oncotarget (2017) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 1c
Cell Signaling Technology Lats1 antibody (Cell Signaling, 9157) was used in western blot on human samples (fig 1c). Mol Cell (2017) ncbi
domestic rabbit monoclonal (D57D3)
  • western blot; human; loading ...; fig 8c
Cell Signaling Technology Lats1 antibody (Cell Signaling, 8654) was used in western blot on human samples (fig 8c). J Clin Invest (2017) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; mouse; 1:100; loading ...; fig 1b
  • western blot; mouse; 1:5000; loading ...; fig 1a
  • immunohistochemistry - paraffin section; human; 1:100; loading ...; fig 3a
In order to assess structural and biochemical phenotypes of neuronal transcriptional repression-induced atypical cell death in patient brains with Huntington's disease, Cell Signaling Technology Lats1 antibody (Cell Signaling, 9157) was used in immunohistochemistry - paraffin section on mouse samples at 1:100 (fig 1b), in western blot on mouse samples at 1:5000 (fig 1a) and in immunohistochemistry - paraffin section on human samples at 1:100 (fig 3a). Acta Neuropathol Commun (2017) ncbi
domestic rabbit monoclonal (D57D3)
  • western blot; human; loading ...; fig 2g
Cell Signaling Technology Lats1 antibody (Cell Signaling, 8654) was used in western blot on human samples (fig 2g). EMBO Rep (2017) ncbi
domestic rabbit monoclonal (D57D3)
  • western blot; human; loading ...; fig s4a
In order to report that DUB3 family deubiquitylating enzymes regulate Hippo pathway activity, Cell Signaling Technology Lats1 antibody (Cell Signaling, 8654) was used in western blot on human samples (fig s4a). PLoS ONE (2017) ncbi
domestic rabbit monoclonal (D57D3)
  • western blot; mouse; 1:1000; loading ...; fig 3a
Cell Signaling Technology Lats1 antibody (Cell Signaling Technology, 8654) was used in western blot on mouse samples at 1:1000 (fig 3a). Nat Commun (2016) ncbi
domestic rabbit monoclonal (D57D3)
  • western blot; human; fig 6
  • western blot; mouse; fig 1
Cell Signaling Technology Lats1 antibody (Cell Signaling, 8654) was used in western blot on human samples (fig 6) and in western blot on mouse samples (fig 1). Sci Rep (2016) ncbi
domestic rabbit monoclonal (D57D3)
  • western blot; human; loading ...; fig s2f
In order to demonstrate that the Hippo, Wnt/beta-catenin, and Notch pathways interact to regulate liver size and inhibit hepatocellular carcinoma, Cell Signaling Technology Lats1 antibody (Cell Signaling, 8654) was used in western blot on human samples (fig s2f). J Clin Invest (2017) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig s5
Cell Signaling Technology Lats1 antibody (cell signalling, 9157) was used in western blot on human samples (fig s5). J Clin Invest (2016) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:500; fig s3
In order to investigate the roles of NF2, LATS1/2, and YAP in the branching morphogenesis of the mouse kidney, Cell Signaling Technology Lats1 antibody (Cell Signaling, 9157) was used in western blot on mouse samples at 1:500 (fig s3). Nat Commun (2016) ncbi
domestic rabbit monoclonal (D57D3)
  • western blot; human; loading ...; fig 4a
  • western blot; mouse; loading ...; fig 4b
Cell Signaling Technology Lats1 antibody (Cell Signaling, 8654) was used in western blot on human samples (fig 4a) and in western blot on mouse samples (fig 4b). J Biol Chem (2016) ncbi
domestic rabbit monoclonal (D57D3)
  • western blot; human; loading ...; fig 4b
Cell Signaling Technology Lats1 antibody (Cell Signaling, 8654) was used in western blot on human samples (fig 4b). J Biol Chem (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; fig 5
Cell Signaling Technology Lats1 antibody (Cell signaling, 9157) was used in western blot on human samples (fig 5). J Biol Chem (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; fig 2f
In order to study GSK3 inhibitor BIS I, YAP-dependent EMT signature in PDAC cell lines, and SMADs expression level, Cell Signaling Technology Lats1 antibody (Cell Signaling, 9157) was used in western blot on human samples (fig 2f). Oncotarget (2016) ncbi
domestic rabbit polyclonal
  • western blot; mouse; fig 5
  • western blot; human; fig 4
Cell Signaling Technology Lats1 antibody (Cell Signaling, 9157) was used in western blot on mouse samples (fig 5) and in western blot on human samples (fig 4). J Biol Chem (2016) ncbi
domestic rabbit monoclonal (D57D3)
  • western blot; human; fig 5
Cell Signaling Technology Lats1 antibody (Cell Signaling, 8654) was used in western blot on human samples (fig 5). Oncotarget (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; fig 4
In order to study the activation mechanisms of core Hippo pathway components, Cell Signaling Technology Lats1 antibody (Cell Signaling Technology, 9157) was used in western blot on human samples (fig 4). EMBO Rep (2016) ncbi
domestic rabbit monoclonal (D57D3)
  • western blot; human; 1:1000; fig 4
Cell Signaling Technology Lats1 antibody (Cell signaling, 8654) was used in western blot on human samples at 1:1000 (fig 4). Nat Commun (2015) ncbi
domestic rabbit monoclonal (D57D3)
  • western blot; human; 1:500
In order to study CDC26 phosphorylation and its effect on the tetratricopeptide repeat subcomplex of APC/C, Cell Signaling Technology Lats1 antibody (Cell Signaling Technology, 8654) was used in western blot on human samples at 1:500. PLoS ONE (2015) ncbi
domestic rabbit monoclonal (D57D3)
  • western blot; mouse; fig 6j
  • western blot; human; fig 6i
Cell Signaling Technology Lats1 antibody (Cell signaling, 8654) was used in western blot on mouse samples (fig 6j) and in western blot on human samples (fig 6i). Dev Cell (2014) ncbi
Articles Reviewed
  1. Bae S, Ni L, Luo X. STK25 suppresses Hippo signaling by regulating SAV1-STRIPAK antagonism. elife. 2020;9: pubmed publisher
  2. Zhou T, Gao B, Fan Y, Liu Y, Feng S, Cong Q, et al. Piezo1/2 mediate mechanotransduction essential for bone formation through concerted activation of NFAT-YAP1-ß-catenin. elife. 2020;9: pubmed publisher
  3. Tanaka H, Homma H, Fujita K, Kondo K, Yamada S, Jin X, et al. YAP-dependent necrosis occurs in early stages of Alzheimer's disease and regulates mouse model pathology. Nat Commun. 2020;11:507 pubmed publisher
  4. Escoll M, Lastra D, Pajares M, Robledinos Antón N, Rojo A, Fernández Ginés R, et al. Transcription factor NRF2 uses the Hippo pathway effector TAZ to induce tumorigenesis in glioblastomas. Redox Biol. 2020;30:101425 pubmed publisher
  5. Kim J, Berrios C, Kim M, SCHADE A, Adelmant G, Yeerna H, et al. STRIPAK directs PP2A activity toward MAP4K4 to promote oncogenic transformation of human cells. elife. 2020;9: pubmed publisher
  6. Zhou L, Wang Q, Zhang H, Li Y, Xie S, Xu M. YAP Inhibition by Nuciferine via AMPK-Mediated Downregulation of HMGCR Sensitizes Pancreatic Cancer Cells to Gemcitabine. Biomolecules. 2019;9: pubmed publisher
  7. Park M, Kim A, Manandhar S, Oh S, Jang G, Kang L, et al. CCN1 interlinks integrin and hippo pathway to autoregulate tip cell activity. elife. 2019;8: pubmed publisher
  8. Rong X, Han Q, Lin X, Kremerskothen J, Wang E. FRMPD1 activates the Hippo pathway via interaction with WWC3 to suppress the proliferation and invasiveness of lung cancer cells. Cancer Manag Res. 2019;11:3395-3410 pubmed publisher
  9. Ibar C, Kirichenko E, Keepers B, Enners E, Fleisch K, Irvine K. Tension-dependent regulation of mammalian Hippo signaling through LIMD1. J Cell Sci. 2018;131: pubmed publisher
  10. Chen B, Liu G. WWC3 inhibits intimal proliferation following vascular injury via the Hippo signaling pathway. Mol Med Rep. 2018;17:5175-5183 pubmed publisher
  11. Wigerius M, Quinn D, Diab A, Clattenburg L, Kolar A, Qi J, et al. The polarity protein Angiomotin p130 controls dendritic spine maturation. J Cell Biol. 2018;217:715-730 pubmed publisher
  12. Zheng X, Dong Q, Zhang X, Han Q, Han X, Han Y, et al. The coiled-coil domain of oncogene RASSF 7 inhibits hippo signaling and promotes non-small cell lung cancer. Oncotarget. 2017;8:78734-78748 pubmed publisher
  13. Peng C, Zhu Y, Zhang W, Liao Q, Chen Y, Zhao X, et al. Regulation of the Hippo-YAP Pathway by Glucose Sensor O-GlcNAcylation. Mol Cell. 2017;68:591-604.e5 pubmed publisher
  14. Kim J, Kim Y, Kim J, Park D, Bae H, Lee D, et al. YAP/TAZ regulates sprouting angiogenesis and vascular barrier maturation. J Clin Invest. 2017;127:3441-3461 pubmed publisher
  15. Yamanishi E, Hasegawa K, Fujita K, Ichinose S, Yagishita S, Murata M, et al. A novel form of necrosis, TRIAD, occurs in human Huntington's disease. Acta Neuropathol Commun. 2017;5:19 pubmed publisher
  16. Heidary Arash E, Shiban A, Song S, Attisano L. MARK4 inhibits Hippo signaling to promote proliferation and migration of breast cancer cells. EMBO Rep. 2017;18:420-436 pubmed publisher
  17. Nguyen H, Kugler J, Cohen S. DUB3 Deubiquitylating Enzymes Regulate Hippo Pathway Activity by Regulating the Stability of ITCH, LATS and AMOT Proteins. PLoS ONE. 2017;12:e0169587 pubmed publisher
  18. Jerić I, Maurer G, Cavallo A, Raguz J, Desideri E, Tarkowski B, et al. A cell-autonomous tumour suppressor role of RAF1 in hepatocarcinogenesis. Nat Commun. 2016;7:13781 pubmed publisher
  19. Boro M, Singh V, Balaji K. Mycobacterium tuberculosis-triggered Hippo pathway orchestrates CXCL1/2 expression to modulate host immune responses. Sci Rep. 2016;6:37695 pubmed publisher
  20. Kim W, Khan S, Gvozdenovic Jeremic J, Kim Y, Dahlman J, Kim H, et al. Hippo signaling interactions with Wnt/?-catenin and Notch signaling repress liver tumorigenesis. J Clin Invest. 2017;127:137-152 pubmed publisher
  21. Matsumoto Y, La Rose J, Kent O, Wagner M, Narimatsu M, Levy A, et al. Reciprocal stabilization of ABL and TAZ regulates osteoblastogenesis through transcription factor RUNX2. J Clin Invest. 2016;126:4482-4496 pubmed publisher
  22. Reginensi A, Enderle L, Gregorieff A, Johnson R, Wrana J, McNeill H. A critical role for NF2 and the Hippo pathway in branching morphogenesis. Nat Commun. 2016;7:12309 pubmed publisher
  23. Sayedyahossein S, Li Z, Hedman A, Morgan C, Sacks D. IQGAP1 Binds to Yes-associated Protein (YAP) and Modulates Its Transcriptional Activity. J Biol Chem. 2016;291:19261-73 pubmed publisher
  24. Feng X, Liu P, Zhou X, Li M, Li F, Wang Z, et al. Thromboxane A2 Activates YAP/TAZ Protein to Induce Vascular Smooth Muscle Cell Proliferation and Migration. J Biol Chem. 2016;291:18947-58 pubmed publisher
  25. Chen X, Stauffer S, Chen Y, Dong J. Ajuba Phosphorylation by CDK1 Promotes Cell Proliferation and Tumorigenesis. J Biol Chem. 2016;291:14761-72 pubmed publisher
  26. Thongon N, Castiglioni I, Zucal C, Latorre E, D Agostino V, Bauer I, et al. The GSK3β inhibitor BIS I reverts YAP-dependent EMT signature in PDAC cell lines by decreasing SMADs expression level. Oncotarget. 2016;7:26551-66 pubmed publisher
  27. Keyvani Chahi A, Martin C, Jones N. Nephrin Suppresses Hippo Signaling through the Adaptor Proteins Nck and WTIP. J Biol Chem. 2016;291:12799-808 pubmed publisher
  28. Dai X, Zhuang L, Wang D, Zhou T, Chang L, Gai R, et al. Nuclear translocation and activation of YAP by hypoxia contributes to the chemoresistance of SN38 in hepatocellular carcinoma cells. Oncotarget. 2016;7:6933-47 pubmed publisher
  29. Kim M, Kim M, Park S, Lee C, Lim D. Role of Angiomotin-like 2 mono-ubiquitination on YAP inhibition. EMBO Rep. 2016;17:64-78 pubmed publisher
  30. Meng Z, Moroishi T, Mottier Pavie V, Plouffe S, Hansen C, Hong A, et al. MAP4K family kinases act in parallel to MST1/2 to activate LATS1/2 in the Hippo pathway. Nat Commun. 2015;6:8357 pubmed publisher
  31. Masuda K, Chiyoda T, Sugiyama N, Segura Cabrera A, Kabe Y, Ueki A, et al. LATS1 and LATS2 phosphorylate CDC26 to modulate assembly of the tetratricopeptide repeat subcomplex of APC/C. PLoS ONE. 2015;10:e0118662 pubmed publisher
  32. Li Q, Li S, Mana Capelli S, Roth Flach R, Danai L, Amcheslavsky A, et al. The conserved misshapen-warts-Yorkie pathway acts in enteroblasts to regulate intestinal stem cells in Drosophila. Dev Cell. 2014;31:291-304 pubmed publisher