This is a Validated Antibody Database (VAD) review about rat Lamp2, based on 36 published articles (read how Labome selects the articles), using Lamp2 antibody in all methods. It is aimed to help Labome visitors find the most suited Lamp2 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Knockout validation
Santa Cruz Biotechnology
rat monoclonal (M3/84)
  • western blot knockout validation; human; fig 3
  • western blot; mouse; fig 1
In order to mediate direct uptake of RNA by lysosomes by lysosomal putative RNA transporter SIDT2, Santa Cruz Biotechnology Lamp2 antibody (Santa Cruz Biotechnology, sc-19991) was used in western blot knockout validation on human samples (fig 3) and in western blot on mouse samples (fig 1). Autophagy (2016) ncbi
Novus Biologicals
mouse monoclonal (H4B4)
  • western blot knockout validation; human; loading ...; fig 1d
  • immunocytochemistry; human; 1:200; fig 5b
Novus Biologicals Lamp2 antibody (Novus Biologicals, NBP2-22217) was used in western blot knockout validation on human samples (fig 1d) and in immunocytochemistry on human samples at 1:200 (fig 5b). Sci Rep (2018) ncbi
Santa Cruz Biotechnology
rat monoclonal (6A430)
  • immunohistochemistry; mouse; loading ...; fig 7h
Santa Cruz Biotechnology Lamp2 antibody (Santa Cruz Biotechnology, 6A430) was used in immunohistochemistry on mouse samples (fig 7h). Cell Mol Gastroenterol Hepatol (2022) ncbi
rat monoclonal (M3/84)
  • immunohistochemistry; mouse; loading ...; fig 4a
Santa Cruz Biotechnology Lamp2 antibody (Santa Cruz Biotechnology, sc-19991) was used in immunohistochemistry on mouse samples (fig 4a). Antioxidants (Basel) (2021) ncbi
rat monoclonal (6A430)
  • western blot; mouse; loading ...; fig 6a
Santa Cruz Biotechnology Lamp2 antibody (Santa Cruz Biotechnology, sc-71492) was used in western blot on mouse samples (fig 6a). Oxid Med Cell Longev (2019) ncbi
rat monoclonal (ABL-93)
  • immunohistochemistry; mouse; 1:100; loading ...; fig 2e
Santa Cruz Biotechnology Lamp2 antibody (Santa Cruz Biotechnology, sc-20004) was used in immunohistochemistry on mouse samples at 1:100 (fig 2e). J Clin Invest (2019) ncbi
rat monoclonal (M3/84)
  • immunohistochemistry; mouse; loading ...; fig 2a
Santa Cruz Biotechnology Lamp2 antibody (Santa, sc-19991) was used in immunohistochemistry on mouse samples (fig 2a). Nat Commun (2018) ncbi
rat monoclonal (M3/84)
  • immunohistochemistry - paraffin section; mouse; 1:1000; loading ...; fig st10
In order to outline the protocols for antibodies used for immunohistochemical studies, Santa Cruz Biotechnology Lamp2 antibody (Santa Cruz, sc-19991) was used in immunohistochemistry - paraffin section on mouse samples at 1:1000 (fig st10). J Toxicol Pathol (2017) ncbi
rat monoclonal (M3/84)
  • immunohistochemistry; mouse; loading ...; fig s6c
Santa Cruz Biotechnology Lamp2 antibody (Santa Cruz, M3/84) was used in immunohistochemistry on mouse samples (fig s6c). Science (2017) ncbi
rat monoclonal (ABL-93)
  • immunocytochemistry; human; 1:50; loading ...; fig 4d
Santa Cruz Biotechnology Lamp2 antibody (Santa Cruz, sc-20004) was used in immunocytochemistry on human samples at 1:50 (fig 4d). Sci Rep (2016) ncbi
rat monoclonal (M3/84)
  • western blot knockout validation; human; fig 3
  • western blot; mouse; fig 1
In order to mediate direct uptake of RNA by lysosomes by lysosomal putative RNA transporter SIDT2, Santa Cruz Biotechnology Lamp2 antibody (Santa Cruz Biotechnology, sc-19991) was used in western blot knockout validation on human samples (fig 3) and in western blot on mouse samples (fig 1). Autophagy (2016) ncbi
rat monoclonal (M3/84)
  • immunohistochemistry - paraffin section; human; 1:250; fig 4
Santa Cruz Biotechnology Lamp2 antibody (Santa Cruz, sc-19991) was used in immunohistochemistry - paraffin section on human samples at 1:250 (fig 4). Dis Model Mech (2016) ncbi
rat monoclonal (M3/84)
  • immunohistochemistry - paraffin section; mouse
Santa Cruz Biotechnology Lamp2 antibody (Santa Cruz, sc 19991) was used in immunohistochemistry - paraffin section on mouse samples . Cell Tissue Res (2016) ncbi
rat monoclonal (M3/84)
  • immunocytochemistry; mouse; 1:100; loading ...; fig 1f
  • immunohistochemistry; mouse; 1:200; loading ...; fig 2c
  • immunohistochemistry - paraffin section; human; 1:100; loading ...; fig 8a
Santa Cruz Biotechnology Lamp2 antibody (Santa Cruz, SC-19991) was used in immunocytochemistry on mouse samples at 1:100 (fig 1f), in immunohistochemistry on mouse samples at 1:200 (fig 2c) and in immunohistochemistry - paraffin section on human samples at 1:100 (fig 8a). Nat Commun (2015) ncbi
rat monoclonal (M3/84)
  • western blot; mouse; 1:200; fig 6
In order to test the effects of statins in decreasing thrombus burden and decreasing vein wall injury in established murine stasis and non-stasis chemical-induced venous thrombosis, Santa Cruz Biotechnology Lamp2 antibody (Santa Cruz Biotechnology Inc, sc-19991) was used in western blot on mouse samples at 1:200 (fig 6). PLoS ONE (2015) ncbi
rat monoclonal (ABL-93)
  • immunocytochemistry; human; fig s5
Santa Cruz Biotechnology Lamp2 antibody (Santa Cruz, sc-20004) was used in immunocytochemistry on human samples (fig s5). Cell Death Dis (2015) ncbi
rat monoclonal (6A430)
  • immunohistochemistry; mouse; loading ...; fig 6c
Santa Cruz Biotechnology Lamp2 antibody (Santa Cruz, 6A430) was used in immunohistochemistry on mouse samples (fig 6c). PLoS ONE (2014) ncbi
Invitrogen
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig 3g
Invitrogen Lamp2 antibody (Thermo/Invitrogen, PA1-655) was used in western blot on mouse samples (fig 3g). Cell Rep (2021) ncbi
domestic rabbit polyclonal (AMC2)
  • western blot; rat; 1:500; fig 1d
Invitrogen Lamp2 antibody (Invitrogen, 51-2,200) was used in western blot on rat samples at 1:500 (fig 1d). Life Sci Alliance (2021) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 1b
Invitrogen Lamp2 antibody (Thermo, PA1-655) was used in western blot on human samples (fig 1b). Curr Biol (2020) ncbi
domestic rabbit polyclonal (AMC2)
  • immunohistochemistry - paraffin section; rat; 1:100; loading ...; fig st10
  • immunohistochemistry - paraffin section; mouse; 1:1000; loading ...; fig st10
In order to outline the protocols for antibodies used for immunohistochemical studies, Invitrogen Lamp2 antibody (Invitrogen, 51-2200) was used in immunohistochemistry - paraffin section on rat samples at 1:100 (fig st10) and in immunohistochemistry - paraffin section on mouse samples at 1:1000 (fig st10). J Toxicol Pathol (2017) ncbi
domestic rabbit polyclonal
  • immunocytochemistry; domestic rabbit; 1:100; loading ...; fig 6a
In order to present structural evidence indicating the formation of microdomains between the acidic and sarcoplasmic reticulum calcium stores in cardiac myocytes, Invitrogen Lamp2 antibody (Thermofisher, PA1-655) was used in immunocytochemistry on domestic rabbit samples at 1:100 (fig 6a). Sci Rep (2017) ncbi
domestic rabbit polyclonal
  • western blot; mouse; fig 1a
In order to test if BAG3 protects the heart from reperfusion injury, Invitrogen Lamp2 antibody (ThermoFisher, PA1-655) was used in western blot on mouse samples (fig 1a). JCI Insight (2016) ncbi
domestic rabbit polyclonal (AMC2)
  • western blot; mouse; 1:4000; loading ...; fig 3a
In order to discuss regulation of mutant huntingtin by transcription factor EB, Invitrogen Lamp2 antibody (Invitrogen, 512200) was used in western blot on mouse samples at 1:4000 (fig 3a). J Huntingtons Dis (2016) ncbi
domestic rabbit polyclonal (AMC2)
  • western blot; mouse; 1:1000; fig 6
In order to research mitochondrial-targeted catalase good for the old mouse proteome but not the young which may function as a reverse antagonistic pleiotropy, Invitrogen Lamp2 antibody (Invitrogen, 51-2200) was used in western blot on mouse samples at 1:1000 (fig 6). Aging Cell (2016) ncbi
domestic rabbit polyclonal (AMC2)
  • immunohistochemistry - paraffin section; mouse; 1:200; fig s6
In order to report that BACE2 and BACE1 inhibition in mice affects melanosome maturation and induces hair depigmentation, Invitrogen Lamp2 antibody (ThermoFisher Scientific, 51-2200) was used in immunohistochemistry - paraffin section on mouse samples at 1:200 (fig s6). Sci Rep (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:10,000; fig 3
In order to discuss how mutations in superoxide dismutase-1 affect the motor system, Invitrogen Lamp2 antibody (Thermo Scientific, PA1-655) was used in western blot on human samples at 1:10,000 (fig 3). Acta Neuropathol Commun (2016) ncbi
domestic rabbit polyclonal (AMC2)
In order to examine the role of lysosome associated membrane proteins in pancreatitis, Invitrogen Lamp2 antibody (Invitrogen, 51-2200) was used . Cell Mol Gastroenterol Hepatol (2015) ncbi
domestic rabbit polyclonal (AMC2)
In order to use of chaperone-mediated autophagy to facilitate lipolysis by degradation of lipid droplet-associated proteins, Invitrogen Lamp2 antibody (Life Technologies, 512200) was used . Nat Cell Biol (2015) ncbi
domestic rabbit polyclonal (AMC2)
In order to examine how chaperone-mediated autophagy and the ubiquitin-proteasomal system are regulated after traumatic brain injury, Invitrogen Lamp2 antibody (Invitrogen, 51-2200) was used . J Neurotrauma (2015) ncbi
domestic rabbit polyclonal (AMC2)
In order to investigate how endolysosomal dysfunction causes Parkinson's disease-related neurodegeneration, Invitrogen Lamp2 antibody (Invitrogen, 51-2200) was used . J Neurosci (2015) ncbi
domestic rabbit polyclonal
In order to investigate gp120 internalization and axonal transport in peripheral nervous system neurons, Invitrogen Lamp2 antibody (Thermo Scientific, PA1-655) was used . ASN Neuro (2015) ncbi
Abcam
domestic rabbit monoclonal (EPR4207(2))
  • immunocytochemistry; human; 1:200; loading ...; fig s2d
Abcam Lamp2 antibody (Abcam, 125,068) was used in immunocytochemistry on human samples at 1:200 (fig s2d). Cell Rep (2022) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig 5g
Abcam Lamp2 antibody (Abcam, 203224) was used in western blot on mouse samples at 1:1000 (fig 5g). J Neuroinflammation (2021) ncbi
domestic rabbit monoclonal (EPR4207(2))
  • western blot; human; 1:1000; loading ...; fig 2d, 2e, s5a
Abcam Lamp2 antibody (Abcam, ab125068) was used in western blot on human samples at 1:1000 (fig 2d, 2e, s5a). Signal Transduct Target Ther (2021) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:800; loading ...; fig 4d
Abcam Lamp2 antibody (Abcam, ab203224) was used in western blot on mouse samples at 1:800 (fig 4d). Front Pharmacol (2020) ncbi
domestic rabbit monoclonal (EPR4207(2))
  • immunohistochemistry; rat; loading ...; fig 5d
  • western blot; rat; loading ...; fig 5a
Abcam Lamp2 antibody (Abcam, ab125068) was used in immunohistochemistry on rat samples (fig 5d) and in western blot on rat samples (fig 5a). Front Mol Neurosci (2018) ncbi
Novus Biologicals
mouse monoclonal (H4B4)
  • immunocytochemistry; human; 1:500; loading ...; fig s2c
Novus Biologicals Lamp2 antibody (Novus, NBP2-22217) was used in immunocytochemistry on human samples at 1:500 (fig s2c). Cell Rep (2022) ncbi
mouse monoclonal (H4B4)
  • western blot knockout validation; human; loading ...; fig 1d
  • immunocytochemistry; human; 1:200; fig 5b
Novus Biologicals Lamp2 antibody (Novus Biologicals, NBP2-22217) was used in western blot knockout validation on human samples (fig 1d) and in immunocytochemistry on human samples at 1:200 (fig 5b). Sci Rep (2018) ncbi
BioVision
  • immunocytochemistry; rat; fig 8
  • immunohistochemistry; rat; fig 6
In order to study the effect of exendin-4 on autophagy clearance in beta cells by utilizing rats with tacrolimus-induced diabetes mellitus, BioVision Lamp2 antibody (BioVision, 3900-100) was used in immunocytochemistry on rat samples (fig 8) and in immunohistochemistry on rat samples (fig 6). Sci Rep (2016) ncbi
Articles Reviewed
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  2. Pillai S, Mahmud I, Mahar R, Griffith C, Langsen M, Nguyen J, et al. Lipogenesis mediated by OGR1 regulates metabolic adaptation to acid stress in cancer cells via autophagy. Cell Rep. 2022;39:110796 pubmed publisher
  3. Zeng H, Chen H, Li M, Zhuang J, Peng Y, Zhou H, et al. Autophagy protein NRBF2 attenuates endoplasmic reticulum stress-associated neuroinflammation and oxidative stress via promoting autophagosome maturation by interacting with Rab7 after SAH. J Neuroinflammation. 2021;18:210 pubmed publisher
  4. Luo R, Fan Y, Yang J, Ye M, Zhang D, Guo K, et al. A novel missense variant in ACAA1 contributes to early-onset Alzheimer's disease, impairs lysosomal function, and facilitates amyloid-β pathology and cognitive decline. Signal Transduct Target Ther. 2021;6:325 pubmed publisher
  5. Wani A, Zhu J, ULRICH J, Eteleeb A, Sauerbeck A, Reitz S, et al. Neuronal VCP loss of function recapitulates FTLD-TDP pathology. Cell Rep. 2021;36:109399 pubmed publisher
  6. Guix F, Capitán A, Casadomé Perales Á, Palomares Perez I, López Del Castillo I, Miguel V, et al. Increased exosome secretion in neurons aging in vitro by NPC1-mediated endosomal cholesterol buildup. Life Sci Alliance. 2021;4: pubmed publisher
  7. Varona S, Puertas L, Galán M, Orriols M, Cañes L, Aguiló S, et al. Rolipram Prevents the Formation of Abdominal Aortic Aneurysm (AAA) in Mice: PDE4B as a Target in AAA. Antioxidants (Basel). 2021;10: pubmed publisher
  8. Shen S, Li B, Dai J, Wu Z, He Y, Wen L, et al. BRD4 Inhibition Protects Against Acute Pancreatitis Through Restoring Impaired Autophagic Flux. Front Pharmacol. 2020;11:618 pubmed publisher
  9. Sundararaman A, Fukushima Y, Norman J, Uemura A, Mellor H. RhoJ Regulates α5β1 Integrin Trafficking to Control Fibronectin Remodeling during Angiogenesis. Curr Biol. 2020;30:2146-2155.e5 pubmed publisher
  10. Zuo Z, Ji M, Zhao K, Su Z, Li P, Hou D, et al. CD47 Deficiency Attenuates Isoproterenol-Induced Cardiac Remodeling in Mice. Oxid Med Cell Longev. 2019;2019:7121763 pubmed publisher
  11. Li B, He J, Lv H, Liu Y, Lv X, Zhang C, et al. c-Abl regulates YAPY357 phosphorylation to activate endothelial atherogenic responses to disturbed flow. J Clin Invest. 2019;129:1167-1179 pubmed publisher
  12. Liu L, An D, Xu J, Shao B, Li X, Shi J. Ac2-26 Induces IKKβ Degradation Through Chaperone-Mediated Autophagy Via HSPB1 in NCM-Treated Microglia. Front Mol Neurosci. 2018;11:76 pubmed publisher
  13. Clemente C, Rius C, Alonso Herranz L, Martín Alonso M, Pollán A, Camafeita E, et al. MT4-MMP deficiency increases patrolling monocyte recruitment to early lesions and accelerates atherosclerosis. Nat Commun. 2018;9:910 pubmed publisher
  14. Nguyen H, Noguchi S, Sugie K, Matsuo Y, Nguyen C, Koito H, et al. Small-Vessel Vasculopathy Due to Aberrant Autophagy in LAMP-2 Deficiency. Sci Rep. 2018;8:3326 pubmed publisher
  15. Furukawa S, Nagaike M, Ozaki K. Databases for technical aspects of immunohistochemistry. J Toxicol Pathol. 2017;30:79-107 pubmed publisher
  16. Fuster J, MacLauchlan S, Zuriaga M, Polackal M, Ostriker A, Chakraborty R, et al. Clonal hematopoiesis associated with TET2 deficiency accelerates atherosclerosis development in mice. Science. 2017;355:842-847 pubmed publisher
  17. Aston D, Capel R, Ford K, Christian H, Mirams G, Rog Zielinska E, et al. High resolution structural evidence suggests the Sarcoplasmic Reticulum forms microdomains with Acidic Stores (lysosomes) in the heart. Sci Rep. 2017;7:40620 pubmed publisher
  18. Su F, Myers V, Knezevic T, Wang J, Gao E, Madesh M, et al. Bcl-2-associated athanogene 3 protects the heart from ischemia/reperfusion injury. JCI Insight. 2016;1:e90931 pubmed publisher
  19. Moosavi M, Sharifi M, Ghafary S, Mohammadalipour Z, Khataee A, Rahmati M, et al. Photodynamic N-TiO2 Nanoparticle Treatment Induces Controlled ROS-mediated Autophagy and Terminal Differentiation of Leukemia Cells. Sci Rep. 2016;6:34413 pubmed publisher
  20. Vodicka P, Chase K, Iuliano M, Tousley A, Valentine D, Sapp E, et al. Autophagy Activation by Transcription Factor EB (TFEB) in Striatum of HDQ175/Q7 Mice. J Huntingtons Dis. 2016;5:249-260 pubmed
  21. Lim S, Jin L, Jin J, Yang C. Effect of Exendin-4 on Autophagy Clearance in Beta Cell of Rats with Tacrolimus-induced Diabetes Mellitus. Sci Rep. 2016;6:29921 pubmed publisher
  22. Basisty N, Dai D, Gagnidze A, Gitari L, Fredrickson J, Maina Y, et al. Mitochondrial-targeted catalase is good for the old mouse proteome, but not for the young: 'reverse' antagonistic pleiotropy?. Aging Cell. 2016;15:634-45 pubmed publisher
  23. Aizawa S, Fujiwara Y, Contu V, Hase K, Takahashi M, Kikuchi H, et al. Lysosomal putative RNA transporter SIDT2 mediates direct uptake of RNA by lysosomes. Autophagy. 2016;12:565-78 pubmed publisher
  24. Galán M, Varona S, Orriols M, Rodríguez J, Aguiló S, Dilmé J, et al. Induction of histone deacetylases (HDACs) in human abdominal aortic aneurysm: therapeutic potential of HDAC inhibitors. Dis Model Mech. 2016;9:541-52 pubmed publisher
  25. Shimshek D, Jacobson L, Kolly C, Zamurovic N, Balavenkatraman K, Morawiec L, et al. Pharmacological BACE1 and BACE2 inhibition induces hair depigmentation by inhibiting PMEL17 processing in mice. Sci Rep. 2016;6:21917 pubmed publisher
  26. Tokuda E, Brännström T, Andersen P, Marklund S. Low autophagy capacity implicated in motor system vulnerability to mutant superoxide dismutase. Acta Neuropathol Commun. 2016;4:6 pubmed publisher
  27. Mareninova O, Sendler M, Malla S, Yakubov I, French S, Tokhtaeva E, et al. Lysosome associated membrane proteins maintain pancreatic acinar cell homeostasis: LAMP-2 deficient mice develop pancreatitis. Cell Mol Gastroenterol Hepatol. 2015;1:678-694 pubmed
  28. Ampem G, Azegrouz H, Bacsadi Ã, Balogh L, Schmidt S, Thuróczy J, et al. Adipose tissue macrophages in non-rodent mammals: a comparative study. Cell Tissue Res. 2016;363:461-78 pubmed publisher
  29. Singh N, Kotla S, Dyukova E, Traylor J, Orr A, Chernoff J, et al. Disruption of p21-activated kinase 1 gene diminishes atherosclerosis in apolipoprotein E-deficient mice. Nat Commun. 2015;6:7450 pubmed publisher
  30. Kaushik S, Cuervo A. Degradation of lipid droplet-associated proteins by chaperone-mediated autophagy facilitates lipolysis. Nat Cell Biol. 2015;17:759-70 pubmed publisher
  31. Park Y, Liu C, Luo T, Dietrich W, Bramlett H, Hu B. Chaperone-Mediated Autophagy after Traumatic Brain Injury. J Neurotrauma. 2015;32:1449-57 pubmed publisher
  32. Kett L, Stiller B, Bernath M, Tasset I, Blesa J, Jackson Lewis V, et al. α-Synuclein-independent histopathological and motor deficits in mice lacking the endolysosomal Parkinsonism protein Atp13a2. J Neurosci. 2015;35:5724-42 pubmed publisher
  33. Kessinger C, Kim J, Henke P, Thompson B, McCarthy J, Hara T, et al. Statins improve the resolution of established murine venous thrombosis: reductions in thrombus burden and vein wall scarring. PLoS ONE. 2015;10:e0116621 pubmed publisher
  34. Berth S, Caicedo H, Sarma T, Morfini G, Brady S. Internalization and axonal transport of the HIV glycoprotein gp120. ASN Neuro. 2015;7: pubmed publisher
  35. Guan J, Zhang X, Sun W, Qi L, Wu J, Qin Z. DRAM1 regulates apoptosis through increasing protein levels and lysosomal localization of BAX. Cell Death Dis. 2015;6:e1624 pubmed publisher
  36. Reibring C, El Shahawy M, Hallberg K, Kannius Janson M, Nilsson J, Parkkila S, et al. Expression patterns and subcellular localization of carbonic anhydrases are developmentally regulated during tooth formation. PLoS ONE. 2014;9:e96007 pubmed publisher