This is a Validated Antibody Database (VAD) review about rat LOC689130, based on 12 published articles (read how Labome selects the articles), using LOC689130 antibody in all methods. It is aimed to help Labome visitors find the most suited LOC689130 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
LOC689130 synonym: ferritin heavy chain

Abcam
rabbit monoclonal (EPR3004Y)
  • western blot; human; 1:1000; loading ...; fig 8b
In order to find the specific gene signature related to iron metabolism consisting of genes regulating iron uptake, mitochondrial FeS cluster biogenesis and hypoxic response, Abcam LOC689130 antibody (Abcam, ab75973) was used in western blot on human samples at 1:1000 (fig 8b). Oncotarget (2017) ncbi
Cell Signaling Technology
rabbit monoclonal (D1D4)
  • immunohistochemistry - paraffin section; mouse; 1:500; loading ...; fig 2c
  • western blot; mouse; loading ...; fig 1b
Cell Signaling Technology LOC689130 antibody (Cell Signaling, 4393) was used in immunohistochemistry - paraffin section on mouse samples at 1:500 (fig 2c) and in western blot on mouse samples (fig 1b). Haematologica (2019) ncbi
rabbit monoclonal (D1D4)
  • western blot; human; 1:1000; loading ...; fig 1g
Cell Signaling Technology LOC689130 antibody (Cell Signaling, 4393) was used in western blot on human samples at 1:1000 (fig 1g). Cell Rep (2017) ncbi
rabbit monoclonal (D1D4)
  • western blot; human; 1:500; loading ...; fig 3c
In order to started the linkage of HFE genotype and exosome phenotype in cancer, Cell Signaling Technology LOC689130 antibody (Cell Signaling, D1D4) was used in western blot on human samples at 1:500 (fig 3c). Biochim Biophys Acta Gen Subj (2017) ncbi
rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig 7B
In order to identify cellular processes that regulate HIF1alpha, Cell Signaling Technology LOC689130 antibody (Cell signaling, 3998) was used in western blot on human samples at 1:1000 (fig 7B). elife (2017) ncbi
rabbit polyclonal
  • western blot; human; fig 4
Cell Signaling Technology LOC689130 antibody (Cell Signaling, 3998) was used in western blot on human samples (fig 4). Sci Rep (2015) ncbi
rabbit polyclonal
  • western blot; human; 1:1000; fig 2
Cell Signaling Technology LOC689130 antibody (Cell Signaling Technology, 3998S) was used in western blot on human samples at 1:1000 (fig 2). Biochem J (2015) ncbi
rabbit monoclonal (D1D4)
  • immunocytochemistry; human; 1:100; fig 5
  • western blot; human; 1:1000; fig 7
Cell Signaling Technology LOC689130 antibody (Cell Signaling, 4393) was used in immunocytochemistry on human samples at 1:100 (fig 5) and in western blot on human samples at 1:1000 (fig 7). Nat Cell Biol (2014) ncbi
rabbit polyclonal
  • western blot; human; 1:1000
Cell Signaling Technology LOC689130 antibody (Cell Signaling, 3998) was used in western blot on human samples at 1:1000. Nature (2014) ncbi
rabbit polyclonal
  • western blot; human; 1:1000
Cell Signaling Technology LOC689130 antibody (Cell Signaling, 3998) was used in western blot on human samples at 1:1000. Cell Death Dis (2013) ncbi
rabbit polyclonal
  • western blot; human
In order to study the role of nucleocytoplasmic trafficing in DNA replication origin checkpoint activation as revealed by quantitative SILAC analysis, Cell Signaling Technology LOC689130 antibody (New England Biolabs Ltd., 3998) was used in western blot on human samples . J Proteome Res (2013) ncbi
rabbit polyclonal
  • western blot; human; 1:1000
Cell Signaling Technology LOC689130 antibody (Cell Signaling Technology, 3998) was used in western blot on human samples at 1:1000. PLoS ONE (2010) ncbi
Articles Reviewed
  1. Santana Codina N, Gableske S, Quiles Del Rey M, Małachowska B, Jedrychowski M, Biancur D, et al. NCOA4 maintains murine erythropoiesis via cell autonomous and non-autonomous mechanisms. Haematologica. 2019;: pubmed publisher
  2. Goodwin J, Dowdle W, Dejesus R, Wang Z, Bergman P, Kobylarz M, et al. Autophagy-Independent Lysosomal Targeting Regulated by ULK1/2-FIP200 and ATG9. Cell Rep. 2017;20:2341-2356 pubmed publisher
  3. Mrowczynski O, Madhankumar A, Slagle Webb B, Lee S, Zacharia B, Connor J. HFE genotype affects exosome phenotype in cancer. Biochim Biophys Acta Gen Subj. 2017;1861:1921-1928 pubmed publisher
  4. Miles A, Burr S, Grice G, Nathan J. The vacuolar-ATPase complex and assembly factors, TMEM199 and CCDC115, control HIF1? prolyl hydroxylation by regulating cellular iron levels. elife. 2017;6: pubmed publisher
  5. Rychtarčíková Z, Lettlova S, Tomkova V, Korenkova V, Langerova L, Simonova E, et al. Tumor-initiating cells of breast and prostate origin show alterations in the expression of genes related to iron metabolism. Oncotarget. 2017;8:6376-6398 pubmed publisher
  6. Funauchi Y, Tanikawa C, Yi Lo P, Mori J, Daigo Y, Takano A, et al. Regulation of iron homeostasis by the p53-ISCU pathway. Sci Rep. 2015;5:16497 pubmed publisher
  7. Bauckman K, Haller E, Taran N, Rockfield S, Ruiz Rivera A, Nanjundan M. Iron alters cell survival in a mitochondria-dependent pathway in ovarian cancer cells. Biochem J. 2015;466:401-13 pubmed publisher
  8. Dowdle W, Nyfeler B, Nagel J, Elling R, Liu S, Triantafellow E, et al. Selective VPS34 inhibitor blocks autophagy and uncovers a role for NCOA4 in ferritin degradation and iron homeostasis in vivo. Nat Cell Biol. 2014;16:1069-79 pubmed publisher
  9. Mancias J, Wang X, Gygi S, Harper J, Kimmelman A. Quantitative proteomics identifies NCOA4 as the cargo receptor mediating ferritinophagy. Nature. 2014;509:105-9 pubmed publisher
  10. Bauckman K, Haller E, Flores I, Nanjundan M. Iron modulates cell survival in a Ras- and MAPK-dependent manner in ovarian cells. Cell Death Dis. 2013;4:e592 pubmed publisher
  11. Mulvey C, Tudzarova S, Crawford M, Williams G, Stoeber K, Godovac Zimmermann J. Subcellular proteomics reveals a role for nucleo-cytoplasmic trafficking at the DNA replication origin activation checkpoint. J Proteome Res. 2013;12:1436-53 pubmed publisher
  12. Straud S, Zubovych I, De Brabander J, Roth M. Inhibition of iron uptake is responsible for differential sensitivity to V-ATPase inhibitors in several cancer cell lines. PLoS ONE. 2010;5:e11629 pubmed publisher