This is a Validated Antibody Database (VAD) review about rat LOC100911485, based on 60 published articles (read how Labome selects the articles), using LOC100911485 antibody in all methods. It is aimed to help Labome visitors find the most suited LOC100911485 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
LOC100911485 synonym: mitofusin-2
Knockout validation
Abcam mouse monoclonal |
| In order to investigate PINK1-Mfn2-Parkin-mediated mitophagy in mouse hearts, Abcam LOC100911485 antibody (Abcam, ab56889) was used in western blot knockout validation on human samples at 1:500 (fig s1b). Science (2015) ncbi |
Abcam mouse monoclonal |
| Abcam LOC100911485 antibody (Abcam, ab56889) was used in western blot knockout validation on mouse samples at 1:1000 (fig s4). J Cell Biol (2015) ncbi |
Abcam mouse monoclonal |
| Abcam LOC100911485 antibody (Abcam, ab56889) was used in western blot knockout validation on mouse samples at 1:1000 (fig 1). Cell Metab (2015) ncbi |
Abcam
mouse monoclonal |
| Abcam LOC100911485 antibody (Abcam, ab56889) was used in western blot on mouse samples (fig 4a). Cell Rep (2018) ncbi |
mouse monoclonal |
| Abcam LOC100911485 antibody (Abcam, ab56889) was used in western blot on mouse samples (fig s1c). Cell Rep (2018) ncbi |
mouse monoclonal |
| Abcam LOC100911485 antibody (abcam, ab56889) was used in western blot on mouse samples (fig 3c). J Mol Histol (2018) ncbi |
rabbit monoclonal (NIAR164) |
| Abcam LOC100911485 antibody (Abcam, ab124773) was used in western blot on mouse samples (fig 5d). Cell Death Dis (2018) ncbi |
mouse monoclonal |
| Abcam LOC100911485 antibody (Abcam, ab56889) was used in western blot on mouse samples at 1:1000 (fig 2a). Endocrinology (2018) ncbi |
rabbit monoclonal (NIAR164) |
| Abcam LOC100911485 antibody (Abcam, ab124773) was used in western blot on rat samples at 1:1000 (fig 5a). PLoS ONE (2017) ncbi |
mouse monoclonal |
| Abcam LOC100911485 antibody (Abcam, 56889) was used in immunohistochemistry on mouse samples (fig 5e), in western blot on mouse samples (fig 2a) and in western blot on human samples (fig 5c). Autophagy (2017) ncbi |
mouse monoclonal |
| Abcam LOC100911485 antibody (Abcam, ab56889) was used in western blot on human samples at 1:5000 (fig 2a). Brain (2017) ncbi |
mouse monoclonal |
| In order to evaluate an approach for correcting mitochondrial fusion, Abcam LOC100911485 antibody (Abcam, ab56889) was used in western blot on mouse samples (fig 4b). Nature (2016) ncbi |
mouse monoclonal |
| In order to study affects of acute minimization of brown adipose tissue function by increased reliance on muscle based thermogenesis, Abcam LOC100911485 antibody (Abcam, ab56889) was used in western blot on mouse samples at 1:2000 (fig 6). J Biol Chem (2016) ncbi |
mouse monoclonal |
| In order to study inhibition of mitochondrial fragmentation and attenuation of kainic acid-induced hippocampal cell death by a mitochondrial division inhibitor, Mdivi-1, Abcam LOC100911485 antibody (Abcam, 56889) was used in western blot on mouse samples (fig s4). BMC Neurosci (2016) ncbi |
mouse monoclonal |
| Abcam LOC100911485 antibody (Abcam, 56889) was used in western blot on human samples (fig s1). J Immunol (2016) ncbi |
rabbit monoclonal (NIAR164) |
| In order to study protection against acute myocardial infaction via hearts lacking Mfn1 and Mfn2, Abcam LOC100911485 antibody (Abcam, ab124773) was used in western blot on mouse samples (fig 1). Cell Death Dis (2016) ncbi |
rabbit polyclonal |
| In order to elucidate how inhibition of vascular smooth muscle cell dedifferentiation through mitochondrial dynamics regulation occurs by glucagon-like peptide 1, Abcam LOC100911485 antibody (Abcam, ab50838) was used in western blot on rat samples at 1:1000 (fig 2). Biochem Pharmacol (2016) ncbi |
mouse monoclonal |
| Abcam LOC100911485 antibody (Abcam, ab56889) was used in immunocytochemistry on mouse samples (fig 2) and in western blot on mouse samples (fig 4). Nature (2016) ncbi |
mouse monoclonal |
| In order to investigate PINK1-Mfn2-Parkin-mediated mitophagy in mouse hearts, Abcam LOC100911485 antibody (Abcam, ab56889) was used in western blot knockout validation on human samples at 1:500 (fig s1b). Science (2015) ncbi |
rabbit polyclonal |
| In order to analyze delay of neurodegeneration by preventing stress-induced OPA1 processing in mitochondria by loss of OMA1, Abcam LOC100911485 antibody (Abcam, ab50838) was used in western blot on mouse samples (fig s2). J Cell Biol (2016) ncbi |
rabbit monoclonal (NIAR164) |
| In order to determine how mitochondrial homeostasis is affected by ubiquitin-mediated regulation of E3 ligase GP78 by MGRN1 in trans, Abcam LOC100911485 antibody (Abcam, ab124773) was used in western blot on human samples at 1:1000 (fig 3). J Cell Sci (2016) ncbi |
mouse monoclonal |
| In order to develop the MitoTimer protein to study individual mitochondria, Abcam LOC100911485 antibody (Abcam, ab56889) was used in flow cytometry on mouse samples (fig 1h). J Mol Cell Cardiol (2016) ncbi |
mouse monoclonal |
| Abcam LOC100911485 antibody (Abcam, ab56889) was used in other on mouse samples at 1:500 (fig s4). Nat Commun (2015) ncbi |
mouse monoclonal |
| Abcam LOC100911485 antibody (Abcam, ab56889) was used in western blot on rat samples (fig 6d). Cell Res (2015) ncbi |
mouse monoclonal |
| Abcam LOC100911485 antibody (Abcam, ab56889) was used in western blot on human samples (fig s1). Nat Neurosci (2015) ncbi |
mouse monoclonal |
| Abcam LOC100911485 antibody (Abcam, ab56889) was used in western blot knockout validation on mouse samples at 1:1000 (fig s4). J Cell Biol (2015) ncbi |
mouse monoclonal |
| Abcam LOC100911485 antibody (Abcam, ab56889) was used in western blot knockout validation on mouse samples at 1:1000 (fig 1). Cell Metab (2015) ncbi |
rabbit polyclonal |
| Abcam LOC100911485 antibody (Abcam, ab50838) was used in western blot on human samples and in western blot on mouse samples . J Mol Cell Cardiol (2015) ncbi |
mouse monoclonal |
| In order to study how obesity alters mitochondria-associated ER membranes, Abcam LOC100911485 antibody (Abcam, ab56889) was used in western blot on mouse samples (fig 3). Nat Med (2014) ncbi |
mouse monoclonal |
| In order to report and characterize the interaction between BECN1 and PARK2, Abcam LOC100911485 antibody (Abcam, ab56889) was used in western blot on human samples at 1:500. Autophagy (2014) ncbi |
rabbit polyclonal |
| Abcam LOC100911485 antibody (Abcam, ab50838) was used in western blot on human samples at 1:1000. CNS Neurosci Ther (2014) ncbi |
rabbit polyclonal |
| Abcam LOC100911485 antibody (Abcam, ab50838) was used in western blot on scFv samples at 1:250. Am J Physiol Regul Integr Comp Physiol (2013) ncbi |
rabbit polyclonal |
| Abcam LOC100911485 antibody (Abcam, ab50838) was used in western blot on human samples and in western blot on rat samples . Cell Death Dis (2013) ncbi |
rabbit polyclonal |
| Abcam LOC100911485 antibody (Abcam, ab50838) was used in western blot on human samples (fig s5). Biosci Rep (2013) ncbi |
rabbit polyclonal |
| Abcam LOC100911485 antibody (Abcam, ab50838) was used in western blot on rat samples at 1:1000. Exp Physiol (2013) ncbi |
Abnova
mouse monoclonal (6A8) |
| Abnova LOC100911485 antibody (Abnova, H00009927-M01) was used in western blot on human samples (fig 2c). J Cell Biol (2018) ncbi |
mouse monoclonal (4H8) |
| Abnova LOC100911485 antibody (Abnova, H00009927-M03) was used in western blot on human samples (fig 2c). J Cell Biol (2018) ncbi |
mouse monoclonal (4H8) |
| Abnova LOC100911485 antibody (Abnova, H00009927-M03) was used in western blot on mouse samples (fig 5j). Mol Cell (2017) ncbi |
mouse monoclonal (6A8) |
| Abnova LOC100911485 antibody (Abnova, H00009927-M01) was used in western blot on mouse samples at 1:1000 (fig 1a). Biochim Biophys Acta Mol Basis Dis (2017) ncbi |
mouse monoclonal (4H8) |
| In order to study the independent occurrence of BAK, BAX, and APAF1 from DRP-1 dependent apoptotic mitochondrial fission to amplify cell death by BID and oxidative stress, Abnova LOC100911485 antibody (Abnova, H0009927-(MO3)) was used in western blot on mouse samples (fig 6). Biochim Biophys Acta (2016) ncbi |
mouse monoclonal (4H8) |
| Abnova LOC100911485 antibody (Abnova, H00009927-M03) was used in western blot on human samples . J Physiol (2016) ncbi |
mouse monoclonal (4H8) |
| Abnova LOC100911485 antibody (Abnova, H00009927-M03) was used in western blot on human samples . Hum Mol Genet (2015) ncbi |
mouse monoclonal (6A8) |
| Abnova LOC100911485 antibody (Abnova, H00009927-M01) was used in immunohistochemistry on mouse samples at 1:600. PLoS ONE (2014) ncbi |
Santa Cruz Biotechnology
mouse monoclonal (XX-1) |
| Santa Cruz Biotechnology LOC100911485 antibody (Santa Cruz, sc-100560) was used in immunohistochemistry on mouse samples at 1:500 (fig 1f). Cell Death Dis (2018) ncbi |
mouse monoclonal (XX-1) |
| In order to research the role of mTOR in mitochondrial dynamics and cell survival, Santa Cruz Biotechnology LOC100911485 antibody (Santa Cruz, sc-100560) was used in western blot on mouse samples (fig 2e). Mol Cell (2017) ncbi |
mouse monoclonal (XX-1) |
| In order to research the protective effect of Mfn2 on dopaminergic neurons, Santa Cruz Biotechnology LOC100911485 antibody (SantaCruz, sc-100560) was used in western blot on human samples (fig 1a) and in western blot on mouse samples (fig 4a). Biochim Biophys Acta Mol Basis Dis (2017) ncbi |
mouse monoclonal (XX-1) |
| In order to propose that Mfn2 contributes to cachexia-induced muscle loss, Santa Cruz Biotechnology LOC100911485 antibody (Santa Cruz, sc-100560) was used in western blot on mouse samples (fig 2g) and in western blot on human samples at 1:100 (fig 1b). Oncol Lett (2016) ncbi |
mouse monoclonal (XX-1) |
| Santa Cruz Biotechnology LOC100911485 antibody (Santa Cruz Biotechnology, sc-100560) was used in western blot on human samples (fig 2a). EMBO Mol Med (2016) ncbi |
mouse monoclonal (XX-1) |
| Santa Cruz Biotechnology LOC100911485 antibody (santa cruz, sc-100560) was used in western blot on human samples at 1:1000 (fig 4a). PLoS ONE (2016) ncbi |
mouse monoclonal (XX-1) |
| Santa Cruz Biotechnology LOC100911485 antibody (Santa Cruz Biotechnology, XX-1) was used in western blot on human samples (fig 1a). J Cell Biol (2016) ncbi |
mouse monoclonal (XX-1) |
| In order to characterize how dengue virus cleaves mitofusins and impairs mitochondrial fusion, Santa Cruz Biotechnology LOC100911485 antibody (Santa Cruz, sc-100560) was used in western blot on human samples (fig 1). PLoS Pathog (2015) ncbi |
mouse monoclonal (XX-1) |
| Santa Cruz Biotechnology LOC100911485 antibody (Santa Cruz, sc-100560) was used in western blot on mouse samples . Mol Neurobiol (2014) ncbi |
Proteintech Group
rabbit polyclonal |
| Proteintech Group LOC100911485 antibody (Proteintech, 12186-1-AB) was used in western blot on mouse samples (fig 3c). Physiol Rep (2017) ncbi |
rabbit polyclonal |
| Proteintech Group LOC100911485 antibody (Proteintech, 12186-1-AP) was used in western blot on mouse samples (fig 4). Mol Psychiatry (2016) ncbi |
Sigma-Aldrich
mouse monoclonal (4H8) |
| In order to research the mechanisms of mitochondrial division, Sigma-Aldrich LOC100911485 antibody (Sigma, WH0009927M3) was used in western blot on human samples (fig sf1). Nature (2016) ncbi |
rabbit polyclonal |
| In order to investigate how the interaction between desmin with the alpha beta crystallin contributes to cardiac health, Sigma-Aldrich LOC100911485 antibody (Sigma, M6444) was used in western blot on mouse samples at 1:1000 (fig 6Aa). J Cell Sci (2016) ncbi |
mouse monoclonal (4H8) |
| In order to study mitochondrial development, neurogenesis, and synapse formation in human induced pluripotent stem cell-derived cortical neurons, Sigma-Aldrich LOC100911485 antibody (Sigma, WH0009927M3) was used in immunocytochemistry on human samples at 1:1000 (fig 4) and in western blot on human samples at 1:1000 (fig 3). Sci Rep (2016) ncbi |
rabbit polyclonal |
| Sigma-Aldrich LOC100911485 antibody (Sigma, M6319) was used in western blot on human samples at 1:1000 (fig 4). Oncotarget (2016) ncbi |
rabbit polyclonal |
| Sigma-Aldrich LOC100911485 antibody (Sigma, M6444) was used in western blot on human samples at 1:1000 (fig 4). Oncotarget (2016) ncbi |
mouse monoclonal (4H8) |
| In order to investigate the contribution of PINK1 and PARKIN to cell death, Sigma-Aldrich LOC100911485 antibody (Sigma-Aldrich, 4H8) was used in immunohistochemistry - paraffin section on human samples (fig 3b). J Biol Chem (2016) ncbi |
rabbit polyclonal |
| Sigma-Aldrich LOC100911485 antibody (Sigma-Aldrich, AV42420) was used in western blot on mouse samples at 1:1000 (fig 5b). Nat Commun (2016) ncbi |
rabbit polyclonal |
| In order to study atrophied skeletal muscle of aged mice and alteration of mitochondrial morphology, Sigma-Aldrich LOC100911485 antibody (Sigma, M6319) was used in western blot on mouse samples at 1:1000 (fig 6). Oncotarget (2015) ncbi |
rabbit polyclonal |
| In order to report how the depletion of distinct plectin isoforms differentially affects mitochondrial network organization and function, Sigma-Aldrich LOC100911485 antibody (Sigma, M6444) was used in western blot on mouse samples (fig 7). Hum Mol Genet (2015) ncbi |
rabbit polyclonal |
| In order to study the effect of diaphragm contractile inactivity on mitochondrial function, Sigma-Aldrich LOC100911485 antibody (Sigma, M6319) was used in western blot on mouse samples . J Appl Physiol (1985) (2015) ncbi |
rabbit polyclonal |
| In order to study how obesity alters mitochondria-associated ER membranes, Sigma-Aldrich LOC100911485 antibody (Sigma, M6319) was used in western blot on mouse samples (fig 3). Nat Med (2014) ncbi |
rabbit polyclonal |
| Sigma-Aldrich LOC100911485 antibody (Sigma, M6319) was used in western blot on mouse samples (fig s7). Circ Res (2015) ncbi |
Articles Reviewed
- Xi Q, Zhang B, Jiang Y, Zhang H, Meng Q, Chen Y, et al. Mitofusin-2 prevents skeletal muscle wasting in cancer cachexia. Oncol Lett. 2016;12:4013-4020 pubmed
- Diokmetzidou A, Soumaka E, Kloukina I, Tsikitis M, Makridakis M, Varela A, et al. Desmin and ?B-crystallin interplay in the maintenance of mitochondrial homeostasis and cardiomyocyte survival. J Cell Sci. 2016;129:3705-3720 pubmed
- Leduc Gaudet J, Picard M, St Jean Pelletier F, Sgarioto N, Auger M, Vallée J, et al. Mitochondrial morphology is altered in atrophied skeletal muscle of aged mice. Oncotarget. 2015;6:17923-37 pubmed
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