This is a Validated Antibody Database (VAD) review about rat Kdm1a, based on 26 published articles (read how Labome selects the articles), using Kdm1a antibody in all methods. It is aimed to help Labome visitors find the most suited Kdm1a antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Kdm1a synonym: Aof2; Kdm1; RGD1562975

Knockout validation
Cell Signaling Technology
domestic rabbit polyclonal
  • immunoprecipitation; human; fig 2
  • western blot; human; 1:1000; fig 2
  • western blot knockout validation; mouse; 1:1000; fig 2
Cell Signaling Technology Kdm1a antibody (Cell Signaling Technology, 2139) was used in immunoprecipitation on human samples (fig 2), in western blot on human samples at 1:1000 (fig 2) and in western blot knockout validation on mouse samples at 1:1000 (fig 2). Nat Commun (2016) ncbi
Santa Cruz Biotechnology
mouse monoclonal (1B2E5)
  • western blot; human; loading ...; fig 1c
Santa Cruz Biotechnology Kdm1a antibody (Santa Cruz Biotechnology Inc, sc-53875) was used in western blot on human samples (fig 1c). Nat Immunol (2019) ncbi
mouse monoclonal (B-9)
  • RNA immunoprecipitation; human; fig 3
Santa Cruz Biotechnology Kdm1a antibody (santa Cruz, sc-271720) was used in RNA immunoprecipitation on human samples (fig 3). Sci Rep (2016) ncbi
mouse monoclonal (B-9)
  • western blot; mouse
In order to study the role of Runx1 and PU.1 in corepressor-coactivator exchange and the potential role of PU.1-recruited corepressors as targets for leukemia differentiation therapy, Santa Cruz Biotechnology Kdm1a antibody (Santa Cruz Biotechnology, sc-271720) was used in western blot on mouse samples . J Biol Chem (2014) ncbi
Abcam
domestic rabbit monoclonal (EPR6825)
  • immunohistochemistry - frozen section; mouse; loading ...; fig 4a
  • immunoprecipitation; mouse; loading ...; fig 5i
  • western blot; mouse; loading ...; fig 5h
In order to investigate the role of lysine specific demethylase 1 in neuronal maturation in the olfactory system, Abcam Kdm1a antibody (Abcam, ab129195) was used in immunohistochemistry - frozen section on mouse samples (fig 4a), in immunoprecipitation on mouse samples (fig 5i) and in western blot on mouse samples (fig 5h). J Comp Neurol (2017) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig S8c
Abcam Kdm1a antibody (Abcam, ab37165) was used in western blot on human samples (fig S8c). Nat Commun (2017) ncbi
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig 4c
In order to identify PEG3 as a KRAB-containing zinc finger protein that interacts with KAP1, Abcam Kdm1a antibody (Abcam, ab37165) was used in western blot on mouse samples (fig 4c). PLoS ONE (2016) ncbi
Invitrogen
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 5c
In order to analyze activity-based probes for the LSD1 enzyme., Invitrogen Kdm1a antibody (ThermoFischer, PA5-17361) was used in western blot on human samples (fig 5c). Bioorg Med Chem (2017) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (C69G12)
  • western blot; human; loading ...; fig 3b
Cell Signaling Technology Kdm1a antibody (Cell Signaling, 2184S) was used in western blot on human samples (fig 3b). elife (2019) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig ex5f
Cell Signaling Technology Kdm1a antibody (Cell Signaling, 2139S) was used in western blot on human samples (fig ex5f). Nature (2019) ncbi
domestic rabbit monoclonal (C69G12)
  • western blot; human; 1:1000; loading ...; fig 5d
Cell Signaling Technology Kdm1a antibody (Cell Signaling, C69G12) was used in western blot on human samples at 1:1000 (fig 5d). J Hematol Oncol (2019) ncbi
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig 2a
Cell Signaling Technology Kdm1a antibody (Cell Signaling, 2139) was used in western blot on mouse samples (fig 2a). elife (2019) ncbi
domestic rabbit monoclonal (C69G12)
  • western blot; mouse; loading ...; fig 1b
Cell Signaling Technology Kdm1a antibody (Cell Signaling, 2184) was used in western blot on mouse samples (fig 1b). J Clin Invest (2018) ncbi
domestic rabbit monoclonal (C69G12)
  • western blot; mouse; loading ...; fig 5b
  • western blot; human; loading ...; fig 1c
In order to find that MKRN2 is a novel p65 ubiquitin E3 ligase, Cell Signaling Technology Kdm1a antibody (Cell Signaling, 2184) was used in western blot on mouse samples (fig 5b) and in western blot on human samples (fig 1c). Sci Rep (2017) ncbi
domestic rabbit polyclonal
  • chromatin immunoprecipitation; human; loading ...; fig s3
Cell Signaling Technology Kdm1a antibody (Cell Signaling, 2139S) was used in chromatin immunoprecipitation on human samples (fig s3). MBio (2017) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:3000; loading ...; fig 3c
  • western blot; human; 1:3000; loading ...; fig 3b
In order to study the interaction between Hap1 and Dcaf7, Cell Signaling Technology Kdm1a antibody (Cell Signaling, 2139) was used in western blot on mouse samples at 1:3000 (fig 3c) and in western blot on human samples at 1:3000 (fig 3b). Proc Natl Acad Sci U S A (2017) ncbi
domestic rabbit monoclonal (C69G12)
  • western blot; mouse; 1:1000; fig 11
Cell Signaling Technology Kdm1a antibody (Cell Signaling, 2184) was used in western blot on mouse samples at 1:1000 (fig 11). J Biol Chem (2016) ncbi
domestic rabbit monoclonal (C69G12)
  • western blot; mouse; 1:1000; fig 5
In order to study how alphav integrins regulate Toll-like receptor signaling and intracellular trafficking, Cell Signaling Technology Kdm1a antibody (Cell Signaling Technology, C69G12) was used in western blot on mouse samples at 1:1000 (fig 5). Nat Commun (2016) ncbi
domestic rabbit polyclonal
  • immunoprecipitation; human; fig 2
  • western blot; human; 1:1000; fig 2
  • western blot knockout validation; mouse; 1:1000; fig 2
Cell Signaling Technology Kdm1a antibody (Cell Signaling Technology, 2139) was used in immunoprecipitation on human samples (fig 2), in western blot on human samples at 1:1000 (fig 2) and in western blot knockout validation on mouse samples at 1:1000 (fig 2). Nat Commun (2016) ncbi
domestic rabbit monoclonal (C69G12)
  • western blot; mouse; fig 6
In order to study how PDLIM1 suppresses NF-kappaB activation, Cell Signaling Technology Kdm1a antibody (Cell Signaling Technology, 2184) was used in western blot on mouse samples (fig 6). Sci Rep (2015) ncbi
domestic rabbit monoclonal (C69G12)
  • immunohistochemistry - paraffin section; human; 1:400; loading ...; fig 5
  • western blot; human; 1:2000; loading ...; fig 3d
Cell Signaling Technology Kdm1a antibody (Cell Signaling, 2184) was used in immunohistochemistry - paraffin section on human samples at 1:400 (fig 5) and in western blot on human samples at 1:2000 (fig 3d). J Cancer Res Clin Oncol (2015) ncbi
domestic rabbit monoclonal (C69G12)
  • immunocytochemistry; human; 1:400
Cell Signaling Technology Kdm1a antibody (Cell Signaling Technology, 2184) was used in immunocytochemistry on human samples at 1:400. Clin Cancer Res (2014) ncbi
domestic rabbit monoclonal (C69G12)
  • western blot; human
Cell Signaling Technology Kdm1a antibody (Cell Signaling, C69G12) was used in western blot on human samples . Oncogene (2013) ncbi
domestic rabbit monoclonal (C69G12)
  • immunocytochemistry; mouse; 1:100
  • western blot; mouse; 1:2000
Cell Signaling Technology Kdm1a antibody (Cell Signaling, 2184) was used in immunocytochemistry on mouse samples at 1:100 and in western blot on mouse samples at 1:2000. Proc Natl Acad Sci U S A (2012) ncbi
EMD Millipore
domestic rabbit polyclonal
  • chromatin immunoprecipitation; human; loading ...; fig 8c
EMD Millipore Kdm1a antibody (EMD Millipore, 17-1053) was used in chromatin immunoprecipitation on human samples (fig 8c). J Hematol Oncol (2017) ncbi
domestic rabbit polyclonal
  • chromatin immunoprecipitation; human; loading ...; fig 5d
EMD Millipore Kdm1a antibody (Millipore, 17-1053) was used in chromatin immunoprecipitation on human samples (fig 5d). Biomed Pharmacother (2017) ncbi
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig 5a
EMD Millipore Kdm1a antibody (Millipore, 17-10531) was used in western blot on mouse samples (fig 5a). J Steroid Biochem Mol Biol (2017) ncbi
Articles Reviewed
  1. Volkman H, Cambier S, Gray E, Stetson D. Tight nuclear tethering of cGAS is essential for preventing autoreactivity. elife. 2019;8: pubmed publisher
  2. Parolia A, Cieslik M, Chu S, Xiao L, Ouchi T, Zhang Y, et al. Distinct structural classes of activating FOXA1 alterations in advanced prostate cancer. Nature. 2019;: pubmed publisher
  3. Wobser M, Weber A, Glunz A, Tauch S, Seitz K, Butelmann T, et al. Elucidating the mechanism of action of domatinostat (4SC-202) in cutaneous T cell lymphoma cells. J Hematol Oncol. 2019;12:30 pubmed publisher
  4. Jo Y, Hamilton J, Hwang S, Garland K, Smith G, Su S, et al. Schnyder corneal dystrophy-associated UBIAD1 inhibits ER-associated degradation of HMG CoA reductase in mice. elife. 2019;8: pubmed publisher
  5. Hatzi K, Geng H, Doane A, Meydan C, LaRiviere R, Cárdenas M, et al. Histone demethylase LSD1 is required for germinal center formation and BCL6-driven lymphomagenesis. Nat Immunol. 2019;20:86-96 pubmed publisher
  6. Raso F, Sagadiev S, Du S, Gage E, Arkatkar T, Metzler G, et al. αv Integrins regulate germinal center B cell responses through noncanonical autophagy. J Clin Invest. 2018;128:4163-4178 pubmed publisher
  7. Coleman J, Lin B, Schwob J. Dissecting LSD1-Dependent Neuronal Maturation in the Olfactory Epithelium. J Comp Neurol. 2017;525:3391-3413 pubmed publisher
  8. Xue M, Liu H, Zhang L, Chang H, Liu Y, Du S, et al. Computational identification of mutually exclusive transcriptional drivers dysregulating metastatic microRNAs in prostate cancer. Nat Commun. 2017;8:14917 pubmed publisher
  9. Shin C, Ito Y, Ichikawa S, Tokunaga M, Sakata Sogawa K, Tanaka T. MKRN2 is a novel ubiquitin E3 ligase for the p65 subunit of NF-κB and negatively regulates inflammatory responses. Sci Rep. 2017;7:46097 pubmed publisher
  10. Nguyen K, Das B, Dobrowolski C, Karn J. Multiple Histone Lysine Methyltransferases Are Required for the Establishment and Maintenance of HIV-1 Latency. MBio. 2017;8: pubmed publisher
  11. Qi F, Liu X, Wu H, Yu X, Wei C, Huang X, et al. Long noncoding AGAP2-AS1 is activated by SP1 and promotes cell proliferation and invasion in gastric cancer. J Hematol Oncol. 2017;10:48 pubmed publisher
  12. Jin Y, Huo B, Fu X, Hao T, Zhang Y, Guo Y, et al. LSD1 collaborates with EZH2 to regulate expression of interferon-stimulated genes. Biomed Pharmacother. 2017;88:728-737 pubmed publisher
  13. Xiang J, Yang S, Xin N, Gaertig M, Reeves R, Li S, et al. DYRK1A regulates Hap1-Dcaf7/WDR68 binding with implication for delayed growth in Down syndrome. Proc Natl Acad Sci U S A. 2017;114:E1224-E1233 pubmed publisher
  14. Ourailidou M, Lenoci A, Zwergel C, Rotili D, Mai A, Dekker F. Towards the development of activity-based probes for detection of lysine-specific demethylase-1 activity. Bioorg Med Chem. 2017;25:847-856 pubmed publisher
  15. He H, Ye A, Kim H, Kim J. PEG3 Interacts with KAP1 through KRAB-A. PLoS ONE. 2016;11:e0167541 pubmed publisher
  16. Patrick N, Griggs C, Icenogle A, Gilpatrick M, Kadiyala V, Jaime Frias R, et al. Class I lysine deacetylases promote glucocorticoid-induced transcriptional repression through functional interaction with LSD1. J Steroid Biochem Mol Biol. 2017;167:1-13 pubmed publisher
  17. Jeong O, Chae Y, Jung H, Park S, Cho S, Kook H, et al. Long noncoding RNA linc00598 regulates CCND2 transcription and modulates the G1 checkpoint. Sci Rep. 2016;6:32172 pubmed publisher
  18. Smagris E, Gilyard S, BasuRay S, Cohen J, Hobbs H. Inactivation of Tm6sf2, a Gene Defective in Fatty Liver Disease, Impairs Lipidation but Not Secretion of Very Low Density Lipoproteins. J Biol Chem. 2016;291:10659-76 pubmed publisher
  19. Acharya M, Sokolovska A, Tam J, Conway K, Stefani C, Raso F, et al. αv Integrins combine with LC3 and atg5 to regulate Toll-like receptor signalling in B cells. Nat Commun. 2016;7:10917 pubmed publisher
  20. Kim Y, Nam H, Lee J, Park D, Kim C, Yu Y, et al. Methylation-dependent regulation of HIF-1α stability restricts retinal and tumour angiogenesis. Nat Commun. 2016;7:10347 pubmed publisher
  21. Ono R, Kaisho T, Tanaka T. PDLIM1 inhibits NF-κB-mediated inflammatory signaling by sequestering the p65 subunit of NF-κB in the cytoplasm. Sci Rep. 2015;5:18327 pubmed publisher
  22. Hsu H, Liu Y, Tseng K, Yang T, Yeh C, You J, et al. CBB1003, a lysine-specific demethylase 1 inhibitor, suppresses colorectal cancer cells growth through down-regulation of leucine-rich repeat-containing G-protein-coupled receptor 5 expression. J Cancer Res Clin Oncol. 2015;141:11-21 pubmed publisher
  23. Sankar S, Theisen E, Bearss J, Mulvihill T, Hoffman L, Sorna V, et al. Reversible LSD1 inhibition interferes with global EWS/ETS transcriptional activity and impedes Ewing sarcoma tumor growth. Clin Cancer Res. 2014;20:4584-97 pubmed publisher
  24. Gu X, Hu Z, Ebrahem Q, Crabb J, Mahfouz R, Radivoyevitch T, et al. Runx1 regulation of Pu.1 corepressor/coactivator exchange identifies specific molecular targets for leukemia differentiation therapy. J Biol Chem. 2014;289:14881-95 pubmed publisher
  25. Sankar S, Bell R, Stephens B, Zhuo R, Sharma S, Bearss D, et al. Mechanism and relevance of EWS/FLI-mediated transcriptional repression in Ewing sarcoma. Oncogene. 2013;32:5089-100 pubmed publisher
  26. Ma P, Pan H, Montgomery R, Olson E, Schultz R. Compensatory functions of histone deacetylase 1 (HDAC1) and HDAC2 regulate transcription and apoptosis during mouse oocyte development. Proc Natl Acad Sci U S A. 2012;109:E481-9 pubmed publisher