This is a Validated Antibody Database (VAD) review about rat Kcnn1, based on 2 published articles (read how Labome selects the articles), using Kcnn1 antibody in all methods. It is aimed to help Labome visitors find the most suited Kcnn1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Kcnn1 synonym: KCa2.1; small conductance calcium-activated potassium channel protein 1; SK1; SKCa 1; SKCa1; potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1; potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1; potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1-like

Alomone Labs
rabbit polyclonal
  • western blot; rat; loading ...; fig 3a
In order to ask if SK channels in the mitochondria inner membrane play an important role in regulating mitochondrial function in chronic cardiac diseases, Alomone Labs Kcnn1 antibody (Alomone, APC-039) was used in western blot on rat samples (fig 3a). Cardiovasc Res (2017) ncbi
rabbit polyclonal
  • immunohistochemistry - frozen section; mouse; 1:200; fig 5
  • immunocytochemistry; mouse; 1:100; fig 3
  • western blot; mouse; 1:1000; fig 1
In order to utilize the mechanosensitive TRPV4 channel in the collecting duct system of kidney that is coupled to expression of a diverse array of Ca2+-activated K+ channels (SK1/3, IK1, BK), Alomone Labs Kcnn1 antibody (Alomone, APC-039) was used in immunohistochemistry - frozen section on mouse samples at 1:200 (fig 5), in immunocytochemistry on mouse samples at 1:100 (fig 3) and in western blot on mouse samples at 1:1000 (fig 1). PLoS ONE (2016) ncbi
Articles Reviewed
  1. Kim T, Terentyeva R, Roder K, Li W, Liu M, Greener I, et al. SK channel enhancers attenuate Ca2+-dependent arrhythmia in hypertrophic hearts by regulating mito-ROS-dependent oxidation and activity of RyR. Cardiovasc Res. 2017;113:343-353 pubmed publisher
  2. Li Y, Hu H, Butterworth M, Tian J, Zhu M, O Neil R. Expression of a Diverse Array of Ca2+-Activated K+ Channels (SK1/3, IK1, BK) that Functionally Couple to the Mechanosensitive TRPV4 Channel in the Collecting Duct System of Kidney. PLoS ONE. 2016;11:e0155006 pubmed publisher