This is a Validated Antibody Database (VAD) review about rat Kcnmb1, based on 6 published articles (read how Labome selects the articles), using Kcnmb1 antibody in all methods. It is aimed to help Labome visitors find the most suited Kcnmb1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Kcnmb1 synonym: BKbeta; BKbeta1; k(VCA)beta-1; slo-beta; slo-beta-1; calcium-activated potassium channel subunit beta-1; BK channel subunit beta-1; calcium-activated potassium channel beta subunit; calcium-activated potassium channel subunit beta; calcium-activated potassium channel, subfamily M subunit beta-1; charybdotoxin receptor subunit beta-1; maxi K channel subunit beta-1; potassium channel subfamily M regulatory beta subunit 1; potassium large conductance calcium-activated channel, subfamily M, beta member 1; slowpoke-beta

Abcam
rabbit polyclonal
  • western blot; rat; 1:1000; fig 4
Abcam Kcnmb1 antibody (Abcam, ab3587) was used in western blot on rat samples at 1:1000 (fig 4). Chin Med J (Engl) (2016) ncbi
rabbit polyclonal
  • western blot; mouse; 1:100
In order to assess the specificity and sensitivity of six commercially available antibodies to BK beta1 using tissues from wild type and KO mice, Abcam Kcnmb1 antibody (Abcam, Ab3587) was used in western blot on mouse samples at 1:100. Physiol Rep (2014) ncbi
rabbit polyclonal
  • western blot; mouse; 1:200; loading ...; fig 3c
In order to test if AKAP150 mediates BKCa channel suppression during hyperglycemia and diabetes mellitus, Abcam Kcnmb1 antibody (Abcam, Ab 3587) was used in western blot on mouse samples at 1:200 (fig 3c). Circ Res (2014) ncbi
Santa Cruz Biotechnology
mouse monoclonal (A-5)
  • immunohistochemistry; rabbit; fig 3a
  • western blot; rabbit; fig 3b
Santa Cruz Biotechnology Kcnmb1 antibody (Santa Cruz, sc-377023) was used in immunohistochemistry on rabbit samples (fig 3a) and in western blot on rabbit samples (fig 3b). Channels (Austin) (2017) ncbi
Alomone Labs
rabbit polyclonal
  • western blot; human; 1:200; loading ...; fig 7b
In order to discover a large-conductance calcium-regulated potassium channel in the inner mitochondrial membrane of human dermal fibroblasts, Alomone Labs Kcnmb1 antibody (Alomone Labs, APC-036) was used in western blot on human samples at 1:200 (fig 7b). Biochem J (2016) ncbi
rabbit polyclonal
  • western blot; mouse; 1:100
In order to assess the specificity and sensitivity of six commercially available antibodies to BK beta1 using tissues from wild type and KO mice, Alomone Labs Kcnmb1 antibody (Alomone, APC-036) was used in western blot on mouse samples at 1:100. Physiol Rep (2014) ncbi
Invitrogen
rabbit polyclonal
  • western blot; human; 1:1000; fig 6b
In order to study the effects of hypertension and aging on the functional changes of large-conductance calcium- and voltage-activated potassium channels, Invitrogen Kcnmb1 antibody (Pierce, PA1-924) was used in western blot on human samples at 1:1000 (fig 6b). J Am Heart Assoc (2016) ncbi
rabbit polyclonal
  • western blot; mouse; 1:100
In order to assess the specificity and sensitivity of six commercially available antibodies to BK beta1 using tissues from wild type and KO mice, Invitrogen Kcnmb1 antibody (Pierce, PA1-924) was used in western blot on mouse samples at 1:100. Physiol Rep (2014) ncbi
Articles Reviewed
  1. Feng D, Nan H, Wang W, Yan L, Du P, Zuo L, et al. Expression and alteration of BKCa channels in the sphincter of Oddi's from rabbits with hypercholesterolemia. Channels (Austin). 2017;11:236-244 pubmed publisher
  2. Kicinska A, Augustynek B, Kulawiak B, Jarmuszkiewicz W, Szewczyk A, Bednarczyk P. A large-conductance calcium-regulated K+ channel in human dermal fibroblast mitochondria. Biochem J. 2016;473:4457-4471 pubmed
  3. Cheng J, Mao L, Wen J, Li P, Wang N, Tan X, et al. Different Effects of Hypertension and Age on the Function of Large Conductance Calcium- and Voltage-Activated Potassium Channels in Human Mesentery Artery Smooth Muscle Cells. J Am Heart Assoc. 2016;5: pubmed publisher
  4. Wang Y, Li J, Ji G, Zhai K, Wang H, Liu X. The Involvement of Ca(2+) Signal Pathways in Distal Colonic Myocytes in a Rat Model of Dextran Sulfate Sodium-induced Colitis. Chin Med J (Engl). 2016;129:1185-92 pubmed publisher
  5. Bhattarai Y, Fernandes R, Kadrofske M, Lockwood L, Galligan J, Xu H. Western blot analysis of BK channel β1-subunit expression should be interpreted cautiously when using commercially available antibodies. Physiol Rep. 2014;2: pubmed publisher
  6. Nystoriak M, Nieves Cintrón M, Nygren P, Hinke S, Nichols C, Chen C, et al. AKAP150 contributes to enhanced vascular tone by facilitating large-conductance Ca2+-activated K+ channel remodeling in hyperglycemia and diabetes mellitus. Circ Res. 2014;114:607-15 pubmed publisher