This is a Validated Antibody Database (VAD) review about rat Kat2b, based on 12 published articles (read how Labome selects the articles), using Kat2b antibody in all methods. It is aimed to help Labome visitors find the most suited Kat2b antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Kat2b synonym: Pcaf; histone acetyltransferase KAT2B; K(lysine) acetyltransferase 2B; p300/CBP-associated factor

Santa Cruz Biotechnology
mouse monoclonal (E-8)
  • western blot; human; loading ...; fig 5b
  • western blot; mouse; loading ...; fig s8e
In order to explore transcriptional regulation mediated by p27, Pax5, and PCAF, Santa Cruz Biotechnology Kat2b antibody (Santa Cruz, sc-13124) was used in western blot on human samples (fig 5b) and in western blot on mouse samples (fig s8e). Nucleic Acids Res (2017) ncbi
mouse monoclonal (E-8)
  • immunocytochemistry; human; 1:500; loading ...; fig 3a
In order to characterize the human lysine acetyltransferases KAT2A and KAT2B, Santa Cruz Biotechnology Kat2b antibody (Santa Cruz, sc-13124) was used in immunocytochemistry on human samples at 1:500 (fig 3a). Nat Commun (2016) ncbi
mouse monoclonal (E-8)
  • immunoprecipitation; human; loading ...; fig 5i
  • western blot; human; 1:200; loading ...; fig 1b, 4c
Santa Cruz Biotechnology Kat2b antibody (Santa Cruz, sc-13124) was used in immunoprecipitation on human samples (fig 5i) and in western blot on human samples at 1:200 (fig 1b, 4c). J Pathol (2016) ncbi
mouse monoclonal (E-8)
  • chromatin immunoprecipitation; human; fig 6
  • western blot; human; fig 3
In order to analyze tamoxifen-resistance in ERalpha-positive breast cancer by degradation of NCoR due to COPS5 amplification and overexpression, Santa Cruz Biotechnology Kat2b antibody (Santa Cruz, sc-13124) was used in chromatin immunoprecipitation on human samples (fig 6) and in western blot on human samples (fig 3). Nat Commun (2016) ncbi
mouse monoclonal (E-8)
  • western blot; mouse; 1:1000
Santa Cruz Biotechnology Kat2b antibody (Santa Cruz, sc-13124) was used in western blot on mouse samples at 1:1000. Toxicol Appl Pharmacol (2015) ncbi
mouse monoclonal (E-8)
  • chromatin immunoprecipitation; mouse; fig 6
Santa Cruz Biotechnology Kat2b antibody (Santa Cruz, sc13124) was used in chromatin immunoprecipitation on mouse samples (fig 6). BMC Biol (2015) ncbi
mouse monoclonal (E-8)
  • western blot; human
Santa Cruz Biotechnology Kat2b antibody (Santa Cruz Biotechnology, sc-13124) was used in western blot on human samples . Arthritis Rheumatol (2015) ncbi
mouse monoclonal (E-8)
  • immunoprecipitation; human; fig s1
  • western blot; human; 1:500; fig s1
Santa Cruz Biotechnology Kat2b antibody (Santa Cruz Biotechnology, sc-13124) was used in immunoprecipitation on human samples (fig s1) and in western blot on human samples at 1:500 (fig s1). Mol Autism (2014) ncbi
mouse monoclonal (E-8)
  • western blot; mouse; fig 6a
Santa Cruz Biotechnology Kat2b antibody (Santa, 13124) was used in western blot on mouse samples (fig 6a). elife (2014) ncbi
mouse monoclonal (E-8)
  • western blot; human
  • chromatin immunoprecipitation; mouse
Santa Cruz Biotechnology Kat2b antibody (Santa, sc13124) was used in western blot on human samples and in chromatin immunoprecipitation on mouse samples . PLoS Genet (2014) ncbi
mouse monoclonal (E-8)
  • chromatin immunoprecipitation; human; 3 ug/time
Santa Cruz Biotechnology Kat2b antibody (Santa Cruz, sc-13124) was used in chromatin immunoprecipitation on human samples at 3 ug/time. Cell Cycle (2010) ncbi
MilliporeSigma
mouse monoclonal (NM11)
  • chromatin immunoprecipitation; mouse; fig 6
MilliporeSigma Kat2b antibody (sigma, P2859) was used in chromatin immunoprecipitation on mouse samples (fig 6). Nucleic Acids Res (2016) ncbi
Articles Reviewed
  1. Perearnau A, Orlando S, Islam A, Gallastegui E, Martinez J, Jordan A, et al. p27Kip1, PCAF and PAX5 cooperate in the transcriptional regulation of specific target genes. Nucleic Acids Res. 2017;45:5086-5099 pubmed publisher
  2. Fournier M, Orpinell M, Grauffel C, Scheer E, Garnier J, Ye T, et al. KAT2A/KAT2B-targeted acetylome reveals a role for PLK4 acetylation in preventing centrosome amplification. Nat Commun. 2016;7:13227 pubmed publisher
  3. Bharathy N, Suriyamurthy S, Rao V, Ow J, Lim H, Chakraborty P, et al. P/CAF mediates PAX3-FOXO1-dependent oncogenesis in alveolar rhabdomyosarcoma. J Pathol. 2016;240:269-281 pubmed publisher
  4. Lu R, Hu X, Zhou J, Sun J, Zhu A, Xu X, et al. COPS5 amplification and overexpression confers tamoxifen-resistance in ER?-positive breast cancer by degradation of NCoR. Nat Commun. 2016;7:12044 pubmed publisher
  5. Akhade V, Dighe S, Kataruka S, Rao M. Mechanism of Wnt signaling induced down regulation of mrhl long non-coding RNA in mouse spermatogonial cells. Nucleic Acids Res. 2016;44:387-401 pubmed publisher
  6. Tyler C, Hafez A, Solomon E, Allan A. Developmental exposure to 50 parts-per-billion arsenic influences histone modifications and associated epigenetic machinery in a region- and sex-specific manner in the adult mouse brain. Toxicol Appl Pharmacol. 2015;288:40-51 pubmed publisher
  7. Almuzzaini B, Sarshad A, Farrants A, Percipalle P. Nuclear myosin 1 contributes to a chromatin landscape compatible with RNA polymerase II transcription activation. BMC Biol. 2015;13:35 pubmed publisher
  8. Zhang Z, Shi L, Song L, Ephrem E, Petri M, Sullivan K. Interferon regulatory factor 1 marks activated genes and can induce target gene expression in systemic lupus erythematosus. Arthritis Rheumatol. 2015;67:785-96 pubmed publisher
  9. Crider A, Thakkar R, Ahmed A, Pillai A. Dysregulation of estrogen receptor beta (ERβ), aromatase (CYP19A1), and ER co-activators in the middle frontal gyrus of autism spectrum disorder subjects. Mol Autism. 2014;5:46 pubmed publisher
  10. Herrera F, Yamaguchi T, Roelink H, Tjian R. Core promoter factor TAF9B regulates neuronal gene expression. elife. 2014;3:e02559 pubmed publisher
  11. Sarshad A, Corcoran M, Al Muzzaini B, Borgonovo Brandter L, von Euler A, Lamont D, et al. Glycogen synthase kinase (GSK) 3? phosphorylates and protects nuclear myosin 1c from proteasome-mediated degradation to activate rDNA transcription in early G1 cells. PLoS Genet. 2014;10:e1004390 pubmed publisher
  12. Gatta R, Mantovani R. Single nucleosome ChIPs identify an extensive switch of acetyl marks on cell cycle promoters. Cell Cycle. 2010;9:2149-59 pubmed