This is a Validated Antibody Database (VAD) review about rat Jag1, based on 23 published articles (read how Labome selects the articles), using Jag1 antibody in all methods. It is aimed to help Labome visitors find the most suited Jag1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Santa Cruz Biotechnology
mouse monoclonal (E-12)
  • immunohistochemistry; mouse; loading ...; fig s4c
Santa Cruz Biotechnology Jag1 antibody (Santa Cruz Biotechnology, sc-390177) was used in immunohistochemistry on mouse samples (fig s4c). Cell Rep (2021) ncbi
mouse monoclonal (E-12)
  • immunohistochemistry; mouse; 1:100; loading ...; fig 4c
Santa Cruz Biotechnology Jag1 antibody (Santa Cruz, sc-390177) was used in immunohistochemistry on mouse samples at 1:100 (fig 4c). Life Sci Alliance (2021) ncbi
mouse monoclonal (1C8)
  • western blot; mouse; 1:500; loading ...; fig 1c, 3d
Santa Cruz Biotechnology Jag1 antibody (Santa Cruz, sc-81515) was used in western blot on mouse samples at 1:500 (fig 1c, 3d). EMBO Mol Med (2020) ncbi
mouse monoclonal (1C8)
Santa Cruz Biotechnology Jag1 antibody (Santa Cruz, sc-81515) was used . Front Pharmacol (2016) ncbi
mouse monoclonal (E-12)
  • western blot; mouse; 1:1000; fig 7b
  • western blot; human; 1:1000; loading ...; fig 3b
Santa Cruz Biotechnology Jag1 antibody (Santa Cruz, sc-390177) was used in western blot on mouse samples at 1:1000 (fig 7b) and in western blot on human samples at 1:1000 (fig 3b). Oncol Lett (2016) ncbi
mouse monoclonal (1C8)
  • immunoprecipitation; rat; 1:200; loading ...; fig 4d
  • western blot; rat; 1:200; loading ...; fig 4f
In order to propose that claudin-4 is required for mAChR-modulated paracellular permeability of epithelial cells and investigate the mechanism, Santa Cruz Biotechnology Jag1 antibody (Santa Cruz, sc-81515) was used in immunoprecipitation on rat samples at 1:200 (fig 4d) and in western blot on rat samples at 1:200 (fig 4f). J Cell Sci (2015) ncbi
Invitrogen
hamsters monoclonal (HMJ1-29)
  • flow cytometry; mouse; 1:1000; loading ...; fig s2
Invitrogen Jag1 antibody (eBioscience, HMJ1-29) was used in flow cytometry on mouse samples at 1:1000 (fig s2). J Immunol (2018) ncbi
hamsters monoclonal (HMJ1-29)
  • flow cytometry; mouse; fig 2a
Invitrogen Jag1 antibody (eBioscience, HMJ1-29) was used in flow cytometry on mouse samples (fig 2a). Nat Immunol (2014) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (28H8)
  • immunohistochemistry - paraffin section; mouse; 1:100; loading ...; fig 1a
Cell Signaling Technology Jag1 antibody (Cell Signaling, 2620) was used in immunohistochemistry - paraffin section on mouse samples at 1:100 (fig 1a). elife (2019) ncbi
domestic rabbit monoclonal (28H8)
  • immunohistochemistry; mouse; loading ...; fig 6a
Cell Signaling Technology Jag1 antibody (Cell Signalling, 2620) was used in immunohistochemistry on mouse samples (fig 6a). elife (2019) ncbi
domestic rabbit monoclonal (28H8)
  • western blot; mouse; 1:1000; loading ...; fig f1s3b
Cell Signaling Technology Jag1 antibody (Cell Signaling, 2620) was used in western blot on mouse samples at 1:1000 (fig f1s3b). elife (2019) ncbi
domestic rabbit monoclonal (28H8)
  • immunohistochemistry - paraffin section; human; 1:150; loading ...; fig 5c
Cell Signaling Technology Jag1 antibody (Cell Signalling Technology, 2620) was used in immunohistochemistry - paraffin section on human samples at 1:150 (fig 5c). elife (2018) ncbi
domestic rabbit monoclonal (28H8)
  • western blot; human; loading ...; fig 3e, 5b
Cell Signaling Technology Jag1 antibody (Cell Signaling Technology, 2620) was used in western blot on human samples (fig 3e, 5b). Cancer Res (2017) ncbi
domestic rabbit monoclonal (28H8)
  • immunoprecipitation; human; fig s2a
  • western blot; human; fig s2a
  • western blot; mouse; loading ...; fig 1c
In order to research the role of vimentin in Notch signaling during angiogenesis, Cell Signaling Technology Jag1 antibody (Cell Signaling, 28H8) was used in immunoprecipitation on human samples (fig s2a), in western blot on human samples (fig s2a) and in western blot on mouse samples (fig 1c). Proc Natl Acad Sci U S A (2017) ncbi
domestic rabbit monoclonal (28H8)
  • immunohistochemistry; mouse; loading ...; fig s9a
  • western blot; mouse; loading ...; fig 1a
In order to demonstrate that the Hippo, Wnt/beta-catenin, and Notch pathways interact to regulate liver size and inhibit hepatocellular carcinoma, Cell Signaling Technology Jag1 antibody (Cell Signaling, 2620) was used in immunohistochemistry on mouse samples (fig s9a) and in western blot on mouse samples (fig 1a). J Clin Invest (2017) ncbi
domestic rabbit monoclonal (28H8)
  • immunohistochemistry - paraffin section; mouse; 1:50; loading ...; fig 5e
  • western blot; mouse; fig 5c
In order to report the phenotypic and genetic changes within the pre-neoplastic mammary epithelium of mice with and without stromal PTEN expression, Cell Signaling Technology Jag1 antibody (Cell Signaling, 2620) was used in immunohistochemistry - paraffin section on mouse samples at 1:50 (fig 5e) and in western blot on mouse samples (fig 5c). Oncogene (2017) ncbi
domestic rabbit monoclonal (28H8)
  • immunocytochemistry; human; fig 1e
  • western blot; human; fig 4e
In order to investigate the role of the RTA-JAG1-Notch pathway in Kaposi's sarcoma-associated herpesvirus reactivation, Cell Signaling Technology Jag1 antibody (Cell Signaling, 2620P) was used in immunocytochemistry on human samples (fig 1e) and in western blot on human samples (fig 4e). PLoS Pathog (2016) ncbi
domestic rabbit monoclonal (28H8)
  • immunohistochemistry - frozen section; mouse; 1:1000; loading ...
Cell Signaling Technology Jag1 antibody (Cell Signaling, 28H8) was used in immunohistochemistry - frozen section on mouse samples at 1:1000. Proc Natl Acad Sci U S A (2016) ncbi
domestic rabbit monoclonal (28H8)
  • western blot; human; fig 6d
Cell Signaling Technology Jag1 antibody (Cell Signaling, 2620) was used in western blot on human samples (fig 6d). Biochem Pharmacol (2016) ncbi
domestic rabbit monoclonal (28H8)
  • western blot; human; loading ...; fig 6a
In order to determine the role of actin-like 6A in hepatocellular carcinoma, Cell Signaling Technology Jag1 antibody (Cell signaling, 2620) was used in western blot on human samples (fig 6a). Hepatology (2016) ncbi
domestic rabbit monoclonal (28H8)
  • western blot; human; fig 1
Cell Signaling Technology Jag1 antibody (Cell Signaling, 2620) was used in western blot on human samples (fig 1). Oncotarget (2015) ncbi
domestic rabbit monoclonal (28H8)
  • western blot; mouse; 1:800; fig 4
Cell Signaling Technology Jag1 antibody (Cell Signaling Technology, 2620) was used in western blot on mouse samples at 1:800 (fig 4). elife (2014) ncbi
domestic rabbit monoclonal (28H8)
  • immunohistochemistry - paraffin section; mouse; fig 4
Cell Signaling Technology Jag1 antibody (Cell Signaling Technology, 2620) was used in immunohistochemistry - paraffin section on mouse samples (fig 4). PLoS Genet (2013) ncbi
Articles Reviewed
  1. Molina L, Zhu J, Li Q, Pradhan Sundd T, Krutsenko Y, Sayed K, et al. Compensatory hepatic adaptation accompanies permanent absence of intrahepatic biliary network due to YAP1 loss in liver progenitors. Cell Rep. 2021;36:109310 pubmed publisher
  2. Chung W, Challagundla L, Zhou Y, Li M, Atfi A, Xu K. Loss of Jag1 cooperates with oncogenic Kras to induce pancreatic cystic neoplasms. Life Sci Alliance. 2021;4: pubmed publisher
  3. Bella P, Farini A, Banfi S, Parolini D, Tonna N, Meregalli M, et al. Blockade of IGF2R improves muscle regeneration and ameliorates Duchenne muscular dystrophy. EMBO Mol Med. 2020;12:e11019 pubmed publisher
  4. Travisano S, Oliveira V, Prados B, Grego Bessa J, Piñeiro Sabarís R, Bou V, et al. Coronary arterial development is regulated by a Dll4-Jag1-EphrinB2 signaling cascade. elife. 2019;8: pubmed publisher
  5. Lawlor K, Zappia L, Lefevre J, Park J, Hamilton N, Oshlack A, et al. Nephron progenitor commitment is a stochastic process influenced by cell migration. elife. 2019;8: pubmed publisher
  6. Nandagopal N, Santat L, Elowitz M. Cis-activation in the Notch signaling pathway. elife. 2019;8: pubmed publisher
  7. Eley L, Alqahtani A, MacGrogan D, Richardson R, Murphy L, Salguero Jimenez A, et al. A novel source of arterial valve cells linked to bicuspid aortic valve without raphe in mice. elife. 2018;7: pubmed publisher
  8. Steinbuck M, Arakcheeva K, Winandy S. Novel TCR-Mediated Mechanisms of Notch Activation and Signaling. J Immunol. 2018;200:997-1007 pubmed publisher
  9. Jin L, Vu T, Yuan G, Datta P. STRAP Promotes Stemness of Human Colorectal Cancer via Epigenetic Regulation of the NOTCH Pathway. Cancer Res. 2017;77:5464-5478 pubmed publisher
  10. Antfolk D, Sjöqvist M, Cheng F, Isoniemi K, Duran C, Rivero Muller A, et al. Selective regulation of Notch ligands during angiogenesis is mediated by vimentin. Proc Natl Acad Sci U S A. 2017;114:E4574-E4581 pubmed publisher
  11. Lin C, Lin W, Cho R, Wang C, Hsiao L, Yang C. TNF-?-Induced cPLA2 Expression via NADPH Oxidase/Reactive Oxygen Species-Dependent NF-?B Cascade on Human Pulmonary Alveolar Epithelial Cells. Front Pharmacol. 2016;7:447 pubmed
  12. Xiao Y, Yang X, Miao Y, He X, Wang M, Sha W. Inhibition of cell proliferation and tumor growth of colorectal cancer by inhibitors of Wnt and Notch signaling pathways. Oncol Lett. 2016;12:3695-3700 pubmed
  13. Kim W, Khan S, Gvozdenovic Jeremic J, Kim Y, Dahlman J, Kim H, et al. Hippo signaling interactions with Wnt/?-catenin and Notch signaling repress liver tumorigenesis. J Clin Invest. 2017;127:137-152 pubmed publisher
  14. Sizemore G, Balakrishnan S, Hammer A, Thies K, Trimboli A, Wallace J, et al. Stromal PTEN inhibits the expansion of mammary epithelial stem cells through Jagged-1. Oncogene. 2017;36:2297-2308 pubmed publisher
  15. Li S, Hu H, He Z, Liang D, Sun R, Lan K. Fine-Tuning of the Kaposi's Sarcoma-Associated Herpesvirus Life Cycle in Neighboring Cells through the RTA-JAG1-Notch Pathway. PLoS Pathog. 2016;12:e1005900 pubmed publisher
  16. Kuzmanov U, Guo H, Buchsbaum D, Cosme J, Abbasi C, Isserlin R, et al. Global phosphoproteomic profiling reveals perturbed signaling in a mouse model of dilated cardiomyopathy. Proc Natl Acad Sci U S A. 2016;113:12592-12597 pubmed
  17. Zhang P, He D, Chen Z, Pan Q, Du F, Zang X, et al. Chemotherapy enhances tumor vascularization via Notch signaling-mediated formation of tumor-derived endothelium in breast cancer. Biochem Pharmacol. 2016;118:18-30 pubmed publisher
  18. Xiao S, Chang R, Yang M, Lei X, Liu X, Gao W, et al. Actin-like 6A predicts poor prognosis of hepatocellular carcinoma and promotes metastasis and epithelial-mesenchymal transition. Hepatology. 2016;63:1256-71 pubmed publisher
  19. Cong X, Zhang Y, Li J, Mei M, Ding C, Xiang R, et al. Claudin-4 is required for modulation of paracellular permeability by muscarinic acetylcholine receptor in epithelial cells. J Cell Sci. 2015;128:2271-86 pubmed publisher
  20. Dong X, Lin Q, Aihara A, Li Y, Huang C, Chung W, et al. Aspartate β-Hydroxylase expression promotes a malignant pancreatic cellular phenotype. Oncotarget. 2015;6:1231-48 pubmed
  21. Katz Y, Li F, Lambert N, Sokol E, Tam W, Cheng A, et al. Musashi proteins are post-transcriptional regulators of the epithelial-luminal cell state. elife. 2014;3:e03915 pubmed publisher
  22. Backer R, Helbig C, Gentek R, Kent A, Laidlaw B, Dominguez C, et al. A central role for Notch in effector CD8(+) T cell differentiation. Nat Immunol. 2014;15:1143-51 pubmed publisher
  23. Reginensi A, Scott R, Gregorieff A, Bagherie Lachidan M, Chung C, Lim D, et al. Yap- and Cdc42-dependent nephrogenesis and morphogenesis during mouse kidney development. PLoS Genet. 2013;9:e1003380 pubmed publisher